Region | Title | System | Version | Edition | Languages | Serial | Status |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Dark: Der finstere Berg | PC | | Original | | | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy | PC | | Original | | CDR3015 | |
| Seek and Destroy Seek & Destroy | CD32 | | Original | | | |
| Sega Bass Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1607 | |
| Sega CD Demo | MCD | | Prototype | | | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Game Honpo: Puyo Puyo セガゲーム本舗 ぷよぷよ | PC | | Original | | | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original | | EI-1266-1 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega Marine Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1606 | |
| Sega Mega Drive Classic Collection Volume 3 | PC | | Original | | SEGA-PC120 | |
| Sega Memorial Selection: Dear 80's Videogame Best 3 | PC | | Ultra 2000/Ultra Series | | MKW-183 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | PC Game Bundle | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally 2: Sega Rally Championship (Install Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally 2: Sega Rally Championship (Play Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Original | | 670-9827 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Mihon-hin | | 670-10314 | |
| Sega Saturn Development Tool Kit | PC | | Original | | 610-5750 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Smash Pack | PC | | Original | | 673-01668 | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack II | PC | | Bundle Version Tiny OEM | | KDGT44 | |
| Sega Touring Car Championship 世嘉巡回车大赛 | PC | | Original | | | |
| Sega Touring Car Championship | PC | | Fair Game: Quality Value | | FG-1306 EUROPEAN | |
| Sega Worldwide Soccer PC | PC | | 3D Power Pack | | 500-0009-50 | |
| Sega Worldwide Soccer PC | PC | | Fair Game | | FG-1281 | |
| SegaSaturn: Graphic & Sound Tools for Macintosh | SS | | Original | | N16-1000 | |
| SegaSaturn: Movie Tools: Cinepak for Sega Saturn | SS | | Hybrid Version | | L17-1000 | |
| Sei Shirasagi Jogakuen Vol. 2: Tsukahara Shiho-hen 聖シラサギ女学園 Vol.2 塚原 シホ編 | PC | | Original | | SCR-1997-02 | |
| Sei Shirasagi Jogakuen Vol. 3: Sunada Misaki-hen 聖シラサギ女学園 Vol.3 砂田 ミサキ編 | PC | | Original | | SCR-1997-03 | |
| Seijo Vampire 聖女ヴァンパイア | PC | | Original | | MMM-7881 | |
| Seikai no Monshou 星界の紋章 | PSX | | Original | | SLPS 02323 | |
| Seikai Risshiden: Kimi wa Nihon no Leader ni Nareru ka! 政界立志伝~君は日本のリーダーになれるか!~ | PC | | | | MSDJ-99094 | |
| Seikaku Shindan Game: Ukiyo-e Sumo-hen 性格診断ゲーム 浮世絵相撲編 | PHOTO-CD | | Original | | NPCD-1005 | |
| Seikimatsu Taimaden Tsumugi-chan SOS 世紀末退魔伝つむぎちゃんSOS | PC | | Original | | EXC-0011 | |
| Seimei Handan 姓名判断 | 3DO | | Original | | FZ-SJ4053 | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Original | | SLPS 01271 | |
| Seirei Shoukan: Princess of Darkness 精霊召喚 ~プリンセス オブ ダークネス~ | PSX | | Taikenban Special Disc | | SLPM 80271 | |
| Seireiki Rayblade 聖霊機ライブレード | PSX | | Original | | SLPS 02652 | |
| Seisenshi Denshou: Jantaku no Kishi 聖戦士伝承 ~雀卓の騎士~ | PCE | | Original | | NBCD4005 | |
| Seishoujo Kantai Virgin Fleet 聖少女艦隊・バージン・フリート | PSX | | Original | | SLPM 86191 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 1) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Seiyuu Kantoku Simulation: Standby Say You! (Disc 2) 声優監督シミュレーション スタンバイSay You! | PC | | | | HMW-1 | |
| Sekai Saikyou Ginsei Igo 世界最強銀星囲碁 | PSX | | Original | | SLPS 03325 | |
| Sekai Saikyou Ginsei Igo 2 世界最強銀星囲碁2 | PSX | | Original | | SLPS 03480 | |
| Sekai Saikyou Ginsei Igo 3 世界最強 銀星囲碁3 | PSX | | Original | | SLPS 03563 | |
| Sell It to Me! Part One: Preparing The Way | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Handling Telephone Sales Enquiries and Making Appraisals Pay | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Paperwork, Bloody Paperwork and Selling to Women | CDI | | Original | | | |
| Selling for Real: Interactive Video Sales Training: Selling You to You and Taking Personal Control | CDI | | Original | | | |
| Sem' Samuraev (Disc 1) Семь Самураев | PC | | Original | | | |
| Sem' Samuraev (Disc 2) Семь Самураев | PC | | Original | | | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! 戦国美少女絵巻 空を斬る!! | PC | | Original | | TGL-98 0220 | |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! Harukaze no Shou 戦国美少女絵巻 空を斬る!! ~春風の章~ | PC | | Original | | | |
| Sengoku Denshou 2 ~ Sengoku 2 戦国伝承2 | NGCD | | Original | | NGCD-040 | |
| Sengoku Mugen 戦国夢幻 | PSX | | Original | | SLPS 03151 | |
| Sengoku Shougi 戦国将棋 | PC | | Power Game 1800 Series | | GA-0001 | |
| Senha N. 1 | PC | | | | | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc 戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senkai Taisen: TV Animation Senkaiden Houshin Engi yori 仙界大戦 ~TVアニメーション仙界伝封神演義より~ | PSX | | Original | | SLPS 02736 | |
| Senkai Tsuuroku Seishi: TV Animation Senkaiden Houshin Engi yori 仙界通録正史 ~TVアニメーション仙界伝封神演義より~ | PSX | | Original | | SLPS 03176 | |
| Senkaku Mondai o Yatchimasu 2 尖閣問題を殺っちます2 | PC | | Original | | | |
| Senran 戦乱 | PSX | | Original | | SLPS 00427 | |
| Senryaku Shidan: Tora! Tora! Tora! Rikusen-hen 戦略師団 トラ!トラ!トラ!陸戦編 | PSX | | PSone Books | | SLPS 91422 | |
| Senryaku Shougi 戦略将棋 | PSX | | Original | | SLPS 00142 | |
| Sensei 2 Запретное влечение | PC | | Original | | | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Sensible Soccer | MCD | | Original | | T-93185-50 | |
| Sensible World of Soccer '96/'97 (Upgrade PC CD-ROM Disc) | PC | | Original | | | |
| Sentient | PC | | Original | | | |
| Sentimental Graffiti センチメンタルグラフティ | PSX | | Original | | SLPS 03184 | |
| Sentimental Graffiti (Disc 1) センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01A | |
| Sentimental Graffiti (Disc 2) センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01B | |
| Sentimental Graffiti: Yakusoku センチメンタルグラフティ~約束~ | PSX | | Original | | SLPS 03183 | |
| Sentimental Journey センチメンタル・ジャーニー | PSX | | Original | | SLPS 01473 | |
| Sentinel Returns | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Sento Monogatari: Sono I 占都物語 そのI | PSX | | Original | | SLPS 00124 | |
| Sento Monogatari: Sono I 「占都物語」 そのI | PC | | Original | | | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 1) (Installation CD-ROM) 戦闘妖精雪風~妖精の舞う空~ | PC | | Original | | SYYi-V1.00 | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 2) (Game CD-ROM) 戦闘妖精雪風~妖精の舞う空~ | PC | | Original | | SYYg-V1.00 | |
| Septentrion: Out of the Blue セプテントリオン ~Out of the Blue~ | PSX | | Original | | SLPS 01940 | |
| Septentrion: Out of the Blue セプテントリオン ~Out of the Blue~ | PSX | | Major Wave | | SLPM 86612 | |
| Septerra Core: Legacy of the Creator | PC | | Covermount | | ADB 0103 | |
| Sequence Palladium シークエンス パラディウム | PC | | Original | | KGDP004 | |
| Sequence Palladium 2 Mania Kit | PC | | Original | | KGD-0060 | |
| Sequence Palladium Mania Kit: Desktop Accessory シークエンス・パラディウム マニアキット デスクトップアクセサリ | PC | | Original | | WIC-6346 | |
| Sequence Palladium Premium Digital Novel | PC | | PC Game Bundle | | KGD-06021 | |
| Seraphim: Saigo no Tenshi セラフィム 最後の天使 | PC | | Original | | SCR-003 | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | | Rerelease | | | |
| Serp i Molot (Disc 1) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 2) Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 3) Серп и Молот | PC | | 1C: Igroteka | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Serum-Werk Bernburg AG: Veterinärpharmaka: Vol. 1 | CDI | | Original | | | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Sesame Street Kazu Asobi: A Visit to Sesame Street: Numbers セサミストリート かずあそび | CDI | | Original | | PCIM-00013 | |
| Sesame Street Moji Asobi: A Visit to Sesame Street: Letters セサミストリート もじあそび | CDI | | Original | | PCIM-00012 | |
| Sesame Street Sports | PSX | | Original | | SLES-03180 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original | | SLES-02510 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Let's Make A Word! | MAC | | Original | | 9281 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Numbers セサミ・ストリート ~ナンバーズ~ | 3DO | | Original | | FZ-SJ1664 | |
| Sesame Street: Numbers Улица Сезам: Учись считать | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Preschool Улица Сезам: Элмо готовит в школу | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesamstrasse: Auf die Krümel, fertig, los! | PC | | Rerelease | | GSL854AG-CD | |
| Session Power Up Kit for DrumMania 2nd Mix / PercussionFreaks 2nd Mix | KS573 | | Original | | 912 *Z A01 | |
| Sethi und das Geheimnis der Neandertaler | PC | | Rerelease | | | |
| Sethi: Abenteuer im Mittelalter National Geographic: Sethi: Abenteuer im Mittelalter | PC | | Original | | | |
| The Settlers II | PC | | Demo | | | |
| The Settlers II: 10-lecie The Settlers II: 10th Anniversary | PC | | eXtra Klasyka Next | | | |
| The Settlers II: 10th Anniversary Die Siedler II: Die nächste Generation | PC | | Gold Edition (Software Pyramide) | | 300025385 | |
| The Settlers II: 10th Anniversary: Vikings Die Siedler II: Die nächste Generation: Wikinger | PC | | Gold Edition (Software Pyramide) | | 300025389 | |
| Settlers II, The: Veni, Vidi, Vici | PC | | Budget | | MMICDR 5803 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 1) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III (Disc 2) | PC | | Revival | | REV036 | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers III: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| The Settlers IV | PC | | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Original | | | |
| The Settlers IV: Gold Edition (Disc 1) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Gold Edition | | | |
| The Settlers IV: Gold Edition (Disc 2) | PC | | Focus Essential | | ESS565 | |
| The Settlers IV: Złota Edycja | PC | | Nowa eXtra Klasyka | | | |
| The Settlers | PC | | Rerelease | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | Strefa Niskich Cen | | | |
| The Settlers | PC | | PC Best Buy Pocket | | 900813 | |
| The Settlers: Heritage of Kings: Gold Edition (Legends Expansion Disc) | PC | | That's Hot! | | 5004531 | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Original | | | |
| Seven Kingdoms II: The Fryhtan Wars | PC | | Cool Games | | | |
| Seven Kingdoms: Ancient Adversaries | PC | | | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
| Seven Years War 2 + Joseonui Bangyeok 임진록 2 + 조선의 반격 | PC | | Hapbon | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 1) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 2) 第七封印:魔神甦醒 | PC | | Original | | | |
| The Seventh Seal: The Resurrection of the Dark Lord (Anzhuang Cidie 3) 第七封印:魔神甦醒 | PC | | Original | | | |
| Sewer Shark | MCD | | Original | | T-93015-50 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Original | | T-6201 | |
| Sex Sensou: Aiaru H wa Kinshi desu! H-na Hiyakeato Patch SEX戦争~愛あるHは禁止ですっ!~Hな日焼け跡パッチ | PC | | Original | | | |
| Sexy Bytes: Housewives 2 | PHOTO-CD | | Original | | | |
| Sexy Bytes: Lacquer & Leather | PHOTO-CD | | Original | | | |
| Sexy Bytes: Office Sex | PHOTO-CD | | Original | | | |
| Sexy Bytes: Outside Dreams | PHOTO-CD | | Original | | | |
| Sexy Bytes: Rolling Mountains | PHOTO-CD | | Original | | | |
| Sexy Bytes: Studio Girls 1 | PHOTO-CD | | Original | | | |
| Sexy in the Hawaii: Nice Gal Hawaii-hen Sexy in The Hawaii ~ナイス・ギャル ハワイ編~ | FMT | | Original | | | |
| Sexy PK: World Cup-ban セクシー・ピーケー ワールドカップ版 | MAC | | Original | | MMC-4065 | |
| Sfera Сфера | PC | | | | | |
| Sfera II: Arena Сфера II: Арена | PC | | Original | | | |
| Sfera: Materik Vlasti Сфера: Материк Власти | PC | | 1C: Kollekciya igrushek | | | |
| Sfera: Prokljatie Giperiona Сфера: Проклятие Гипериона | PC | | 1C: Kollekciya igrushek | | | |
| Sfida nella Piramide! | PC | | Evviva! Software | | | |
| Shade: Wrath of Angels (Press Disc) | PC | | Press Kit | | | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-UK1 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-UK2 | |
| Shadoan | PC | | Interactive Preview | | | |
| Les Shadoks: Le Jeu: La Promenade | PC | | Original | | PCMCSHAD97FCD1 | |
| Shadow Company: Left for Dead | PC | | Back to Games | | | |
| Shadow Company: Left for Dead (Digital Press Kit) | PC | | Press Kit | | 5051895 | |
| Shadow Fight (Disc 1) Бой с тенью | PC | | Original | | | |
| Shadow Fight (Disc 2) Бой с тенью | PC | | Original | | | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Shadow Force: Razor Unit | PC | | Special Forces Pack | | SFRU-0414 | |
| Shadow Hearts: Special Disc SHADOW HEARTS スペシャルディスク | PC | | Hibaihin | | | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02100 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12100 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02101 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12101 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02102 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12102 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02103 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12103 | |
| Shadow Man | PC | | Rerelease | | CD196141.01-ENG | |
| Shadow Man | PC | | Back to Games | | CD 60600 | |
| Shadow Man | PC | | Original | | CD194141.05-ITA | |
| Shadow Man | PC | | Wanted Games | | CD194141.00-EUR | |
| Shadow Man シャドウマン | PC | | Original | | ACLC-W1007E1 | |
| Shadow Man | PC | | Demo | | | |
| Shadow Man | PC | | Original | | | |
| Shadow Man: Rette deine Seele | PC | | Original | | CD194141.03-GER | |
| Shadow Master | PC | | Dice | | DCG 005141, DMM 005424 | |
| Shadow of the Beast | PCE | | Original | | TGXCD1018 | |
| Shadow of the Beast II | MCD | | Original | | T-113045 | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadow Vault Bonus CD Extra 1/2008 | PC | | | | | |
| Shadow Vault: Demos and Materials | PC | | Original | | | |
| Shadow Warrior: Digital Press Kit | PC | | Press Kit | | | |
| Shadow Watch | PC | | Original | | | |
| Shadowbane | PC | | Taikenban | | | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| Shadowgrounds (Disc 1) (Installation) | PC | | Original | | Art.-Nr. 9702270 | |
| Shadowgrounds (Disc 2) (Spiel) | PC | | Original | | Art.-Nr. 9702270 | |
| Shadowlands | PC | | Megapak 2 | | | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shakii il Lupo Shakii the Wolf | PC | | Microforum | | | |
| Shakii the Wolf | PC | | Original | | | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shane Warne Cricket | PSX | | Original | | SLES-01576 | |
| Shanggu Juanzhou III: Chenfeng (Disc B) 上古卷轴Ⅲ:晨风 | PC | | Zhima Kai Men | | | |
| Shanghai 上海 | FMT | | Original | | HMB-192 | |
| Shanghai Dafuweng 1940 上海大富翁1940 | PC | | Fengyun Dafuweng Bundle | | | |
| Shanghai Double Pack | PC | | Original | | | |
| Shanghai Dragon | PC | | Covermount | | | |
| Shanghai Gensoutan: Teito Kitan Gaiden (Disc Kou) 上海幻想譚 ~帝都奇譚外伝~ | PC | | Original | | | |
| Shanghai Gensoutan: Teito Kitan Gaiden (Disc Otsu) 上海幻想譚 ~帝都奇譚外伝~ | PC | | Original | | | |
| Shanghai Ubi Quanxin Youxi Zhanshipan 上海育碧全新游戏展示盘 | PC | | PC Game Bundle | | | |
| Shanghai: Banri no Choujou 上海 万里の長城 | PSX | | Mouse Set Tsuki Gentei Box | | SCPS 10005 | |
| Shanghai: Banri no Choujou 上海 ~万里の長城~ | PC-FX | | Original | | FXNHE507 | |
| Shanghai: Banri no Choujou: The Great Wall 上海 ~万里の長城~ | 3DO | | Original | | FZ-SJ1660 | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Shanghai: Great Moments 上海 グレートモーメンツ | PSX | | Original | | SLPS 00266 | |
| Shanghai: Second Dynasty | PC | | Xplosiv | | EI-1588 ENGLISH | |
| Shanghai: True Valor | PSX | | Original | | SLES-01618 | |
| Shangrlia 2 シャングリラ2 | FMT | | Original | | HME-220 | |
| Shaolin | PSX | | Preview | | | |
| Shaolin Shiba Tongren 少林十八銅人 | PC | | Original | | | |
| Shape Shifter | PCE | | Original | | TGXCD1021 | |
| Shape Shifter | PC | | Original | | | |
| Shareware CD Compilation n.40: Doom 1800 Niveaux | PC | | | | 1634 | |
| Shareware Games: The Best of 1996: Luglio/Agosto 1996 | PC | | | | | |
| Shareware Gold: PC Software | PC | | Original | | SGCD-01 | |
| Shareware-Hits zum Superpreis: Top 100 Spiele | PC | | Original | | | |
| Shari Lewis Lamb Chop's Play-Along! Action Songs | CDI | | Original | | 310690289-2 | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| Shediao Yingxiongzhuan 射鵰英雄傳 | PSX | | Original | | SCPS 45510 | |
| Sheep | PC | | | | EI-1246 | |
| Sheep | PC | | Megapak 10 | | EI-1420 GERMAN | |
| Sheep | PC | | Original | | EI-1247 | |
| Sheep シープ | PSX | | Pokkiri 1400 | | SLPM 87020 | |
| Sheep | PC | | | | | |
| Sheep, Dog 'n' Wolf | PC | | Original | | SHEDOPCD | |
| Sheep, Dog 'n' Wolf | PC | | | | 1008993 | |
| Sheep, Dog 'n' Wolf: Interactive Demo | PSX | | Demo | | SLED-03631 | |
| Shellshock | PC | | Kixx | | | |
| Shellshock | PC | | Original | | | |
| Shellshock | PSX | | Original | | SLES-00215 | |
| Shellshock | PSX | | Original | | SLES-00216 | |
| Shellshock | PC | | Original | | | |
| Shellshock: Jus' Keepin' da Peace シェルショック | PSX | | Original | | SLPS 00486 | |
| Shen Hua 神話 | PC | | Original | | | |
| Shendiao Xialü 神鵰俠侶 | PC | | Original | | | |
| Shendiao Xialü 神鵰俠侶 | PC | | Original | | | |
| Shendiao Xialü 神鵰俠侶 | PC | | Original | | | |
| Sheng-Hua Weiji 生化危机 | PC | | Original | | | |
| Sheng-Hua Weiji 生化危机 | PC | | Sheng-Hua Weiji Xilie Daheji | | | |
| Sheng-Hua Weiji: Qiangxia Youhun 生化危机:枪下游魂 | PC | | Original | | | |
| Shengjie Zhi Qiji 圣界之奇迹 | PC | | Rerelease | | | |
| Shenlong Shaonian 神龙少年 | PC | | Original | | | |
| Shenmue III | PC | | Backer Exclusive Edition | | | |
| Shenshui Yugang 深水鱼缸 | PC | | Original | | | |
| Shentan Jack 神探杰克 | PC | | Original | | | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Original | | MTC000653-D | |
| Sherlock Holmes: Consulting Detective | MCD | | Original | | 4650 | |
| Sherlock Holmes: Consulting Detective: Vol. I | VIS | | Original | | 25-6183 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Rerelease | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 2) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II | VIS | | Original | | 25-6184 | |
| Sherlock Holmes: Consulting Detective: Vol. II | PCE | | Original | | TGXCD1039 | |
| Sherlock Holmes: Das Geheimnis des persischen Teppichs | PC | | Original | | Artikel Nummer 31173 | |
| Sherlock Holmes: The Case of the Silver Earring (Disc 1) | PC | | Reload / White Label | | 1480A1 | |
| Sherlock Holmes: The Case of the Silver Earring (Disc 2) | PC | | Reload / White Label | | 1480A2 | |
| Sherlok Xolms: Pyat' egipetskix statue'tok Шерлок Холмс: Пять египетских статуэток | PC | | 1C: Igroteka | | | |
| Sherlok Xolms: Vozvrashhenie Moriarti Шерлок Холмс: Возвращение Мориарти | PC | | Original | | | |
| Sherman M4 | PC | | Action Sixteen | | | |
| Shewang: Baozhu Chuanshuo 蛇王:宝珠传说 | PC | | Original | | | |
| Shi Naki Shijin no Gogo 詩なき詩人の午後 | PC | | Original | | | |
| Shiawase Usagi II: Toraware Usagi Sailor Z しあわせうさぎⅡ とらわれうさぎセーラーZ | PCE | | Unlicensed | | | |
| Shiawase Usagi: Nureta Bishoujo: Hajimete Nanoni... しあわせうさぎ ~濡れた美少女‐初めてなのに…~ | PCE | | Unlicensed | | | |
| Shichida-shiki Unou de Asobenture Vol. 1: Kotoba ABC: 0-2-sai Muke 七田式 右脳でアソベンチャー① 【ことばABC 0歳~2歳向け】 | PSX | | Original | | SLPM 86527 | |
| Shichida-shiki Unou de Asobenture Vol. 2: Katachi 123: 0-2-sai Muke 七田式 右脳でアソベンチャー② 【かたち123 0歳~2歳向け】 | PSX | | Original | | SLPM 86528 | |
| Shichida-shiki Unou de Asobenture Vol. 3: Kotoba ABC: 2-4sai Muke 七田式 右脳で遊勉チャー③ 【ことばABC 2歳~4歳向け】 | PSX | | Original | | SLPM 86529 | |
| Shichida-shiki Unou de Asobenture Vol. 4: Katachi 123: 2-4-sai Muke 七田式 右脳でアソベンチャー④ 【かたち123 2歳~4歳向け】 | PSX | | Original | | SLPM 86530 | |
| Shichida-shiki Unou de Asobenture Vol. 5: Kotoba ABC: 4-6-sai Muke 七田式 右脳でアソベンチャー⑤ 【ことばABC 4歳~6歳向け】 | PSX | | Original | | SLPM 86531 | |
| Shichida-shiki Unou de Asobenture Vol. 6: Katachi 123: 4-6-sai Muke 七田式 右脳でアソベンチャー⑥ 【かたち123 4歳~6歳向け】 | PSX | | Original | | SLPM 86532 | |
| Shichisei Toushin Guyferd: Crown Kaimetsu Sakusen 七星闘神ガイファード ~クラウン壊滅作戦~ | PSX | | Original | | SLPS 01619 | |
| Shichuu Suimei Pitagraph 四柱推命 ~PITAGRAPH~ | PSX | | Original | | SLPS 00082 | |
| Shiho Shashin-shuu SHIHO写真集 | PHOTO-CD | | Original | | FZ-JJ1YP0401 | |
| Shijie Qiangwang 世界枪王 | PC | | Original | | | |
| Shijou Saikyou no Video Bible: The Greatest Video Bible in the World 史上最強のビデオバイブル | FMT | | Original | | HMA-251 | |
| Shiken ni Deru!? Haruno-chan 試験に出る!?はるのちゃん | PC | | Original | | MAY-20112 | |
| Shiki no Kyouken 四季の狂剣 | PC | | Original | | | |
| Shiki o Irodoru: Nihon no Shouka: Aki 四季を彩る 日本の唱歌 秋 | FMT | | Original | | HMC-103 | |
| Shiki o Irodoru: Nihon no Shouka: Fuyu 四季を彩る 日本の唱歌 冬 | FMT | | Original | | HMC-104 | |
| Shiki o Irodoru: Nihon no Shouka: Haru 四季を彩る 日本の唱歌 春 | FMT | | Original | | HMC-101 | |
| Shiki o Irodoru: Nihon no Shouka: Natsu 四季を彩る 日本の唱歌 夏 | FMT | | Original | | HMC-102 | |
| Shiki Oriori no Bass Tsuri 四季おりおりのバス釣り | PSX | | Original | | SLPS 02810 | |
| Shikigami no Shiro Evolution (Tokuten Data CD-ROM: Complete) 式神の城 EVOLUTION | PC | | Kurenai | | Q68-00001 KI001E01 | |
| Shikigami no Shiro EX 式神の城EX | PC | | Original | | MQD-3790 | |
| Shikigami No Shiro: Game Illustrations Art Book | PC | | Bundled with Book | | | |
| Shikyokusei (Alpha Disc) 指極星 | PC | | Original | | KGD-0130 | |
| Shikyokusei (Beta Disc) 指極星 | PC | | Original | | KGD-0131 | |
| Shimada Youko: Quatre 島田陽・子カトル | PHOTO-CD | | Original | | FZ-JJ1YP0501 | |
| Shin Jidaigeki Action: Rasetsu no Ken 新時代劇アクション ~羅刹の剣~ | PSX | | Original | | SLPM 86177 | |
| Shin Masou Kishin: Panzer Warfare 真・魔装機神 -PANZER WARFARE- | PSX | | Original | | SLPS 02319 | |
| Shin Master of Monsters Final 真・マスターオブモンスターズ Final | PC | | SystemSoft Selection 2000 | | SSA0028 | |
| Shin Megami Tensei 真・女神転生 | PCE | | Original | | ATCD3006 | |
| Shin Megami Tensei If... 真・女神転生if… | PSX | | Karukozaka Koukou 50th Anniversary Pack | | SLPM 87153 | |
| A Shin Megami Tensei: Devil Children: Kuro no Shoka no Sho 真・女神転生デビルチルドレン 黒の書・赤の書 | PSX | | Original | | SLPM 87040 | |
| Shin Onryou Senki 真怨霊戦記 | PCE | | Original | | FCCD5003 | |
| Shin Onryou Senki (Disc 1) 真怨霊戦記 | PC | | Original | | | |
| Shin Onryou Senki (Disc 2) 真怨霊戦記 | PC | | Original | | | |
| Shin Samurai Spirits: Haoumaru Jigokuhen 真サムライ・スピリッツ ~覇王丸地獄変~ | PC | | Ultra 2000/Ultra Series | | MKW-266 | |
| Shin Sangoku Musou 3: Fan Disc 「真・三國無双3」ファンディスク | PC | | Hibaihin | | GCITY-65248 | |
| Shin Seiki Evangelion: Ayanami Ikusei Keikaku (Disc 1) 新世紀エヴァンゲリオン 綾波育成計画 | PC | | Original | | | |
| Shin Seiki Evangelion: Ayanami Ikusei Keikaku (Disc 1) 新世紀エヴァンゲリオン 綾波育成計画 | PC | | Rerelease | | | |
| Shin Seiki Evangelion: Ayanami Ikusei Keikaku (Disc 2) 新世紀エヴァンゲリオン 綾波育成計画 | PC | | Original | | | |
| Shin Seiki Evangelion: Ayanami Ikusei Keikaku (Disc 2) 新世紀エヴァンゲリオン 綾波育成計画 | PC | | Rerelease | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc A) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc B) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc C) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc D) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PC | | Original | | | |
| Shin Senki Van-Gale: The War of Neo-Century 新戦記ヴァンゲイル | PSX | | Original | | SLPS 00873 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWB-7007 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | Original | | EMW-4034 | |
| Shin Theme Park: Yuuenchi o Tsukurou 新テーマパーク 遊園地をつくろう | PC | | EA Best Selections | | EMWD-711 | |
| Shinc | FMT | | Original | | HME-131 | |
| Shine Memories シャインメモリーズ | PC | | Original | | | |
| Shine: Die Angst hat einen Namen (Disc 1) | PC | | Original | | 768964 24472 | |
| Shine: Die Angst hat einen Namen (Disc 2) | PC | | Original | | 768964 24472 | |
| Shingaku Banchou Kanzenban Fullvoice 神学番長 完全版 ―FULLVOICE― | PC | | PIL/SLASH Maker Tsuuhan Tokuten | | PIL-B007-D1 | |
| Shingata Kururin Pa! 新型くるりんPA! | PSX | | Original | | SLPS 00414 | |
| Shining Force CD | MCD | | Original | | 4656-50 | |
| Shining Soul II + Shining Force Assets Shining Soul 2 + Shining Force Assets | PC | | Press Kit | | | |
| Shinji to Yukai na Nakama-tachi: Second Hanafuda Impact シンジと愉快な仲間たち セカンド・花札いんぱくと | PC | | Original | | V-990070J | |
| Shinjuwan Kougeki Taiheiyou Sensen 3: For Combat Flight Simulator 真珠湾攻撃 太平洋戦線3 For Combat Flight Simulator | PC | | Original | | | |
| Shinkyoku Soukai Polyphonica Episode 1 & 2-wa 神曲奏界ポリフォニカ 1&2話 | PC | | Box Edition | | | |
| Shinma Kourin 神魔降臨 | PC | | Original | | ICCD-005 | |
| Shinobi no Roku 忍ノ六 | PSX | | Original | | SLPS 02877 | |
| Shinpi no Sekai: El Hazard 神秘の世界 エルハザード | PHOTO-CD | | Original | | PIRW-1010 | |
| The Shinri Game 10 ザ・心理ゲーム10 | PSX | | Original | | SLPS 03174 | |
| The Shinri Game 5 ザ・心理ゲーム5 | PSX | | Original | | SLPS 02518 | |
| The Shinri Game 6 ザ・心理ゲーム6 | PSX | | Original | | SLPS 02668 | |
| The Shinri Game 9 ザ・心理ゲーム9 | PSX | | Original | | SLPS 03109 | |
| The Shinri Game ザ・心理ゲーム | PSX | | Original, Renkaban | | SLPS 00169 … | |
| Shinseiden Megaseed: Fukkatsu-hen 神聖伝メガシード ~復活編~ | PSX | | Original | | SLPS 00925 | |
| Shinseiki Kouboushi: Dead Force 新世紀興亡史 デッド・フォース | FMT | | Original | | | |
| Shinsetsu Kamiya Ukyo 3: Missing Link 真説 神谷右京3 ~Missing Link~ | PC | | Original | | | |
| Shinsetsu Shiawase Usagi 真説しあわせうさぎ | PCE | | Unlicensed | | | |
| Shinsetsu Shiawase Usagi 2: Kairaku e no Invitation 真説しあわせうさぎ2 ~快楽へのインビテーション~ | PCE | | Unlicensed | | | |
| Shinsetsu Shiawase Usagi f: Yuujou yorimo Aiyoku 真説しあわせうさぎf ~友情より愛欲~ | PCE | | Unlicensed | | | |
| Shinsou Kaiten!! Wan Wan Umi Monogatari: Sanyo Pachinko Paradise DX 新装開店!! わんわん海物語 ~三洋パチンコパラダイス DX~ | PSX | | Original | | SLPS 03312 | |
| The Ship | PC | | Press Kit | | | |
| Shippuu Dotou!! 疾風怒濤!! | PC | | Original | | ZP-0002 | |
| Shirotsumesouwa: Episode of the Clovers (Disc 1) 白詰草話 -Episode of the Clovers- | PC | | Shokai Genteiban | | | |
| Shirotsumesouwa: Episode of the Clovers (Disc 2) 白詰草話 -Episode of the Clovers- | PC | | Shokai Genteiban | | | |
| Shirotsumesouwa: Episode of the Clovers: Extra Compact Disc 『白詰草話 -Episode of the Clovers-』エクストラCD | PC | | Original | | | |
| Shisenfuu Gekikara Mahjong 四川風激辛麻雀 | PSX | | Original | | SLPS 01648 | |
| Shissou, Yankee Tamashii. 疾走、ヤンキー魂。 | PC | | BB Games Online Game Fantasista | | disc_02 | |
| Shitai o Arau 肢体を洗う | PC | | Demo | | SLKC027 | |
| Shitsuren しつれん | PC | | Original | | | |
| Shivers | PC | | Original | | | |
| Shivers | PC | | SierraOriginals | | S6480120Z12ZZ | |
| Shivers | PC | | Original | | S4430210Z12ZZ | |
| Shivers | PC | | Demo | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |
| Shizuku 雫 ~しずく~ | PC | | Leaf Visual Novel Series Vol. 1 | | | |
| Shkol'noe priklyuchenie: Ostrov sokrovishh i znanij Школьное приключение: Остров сокровищ и знаний | PC | | Original | | | |
| Shkola dressirovki Школа дрессировки | PC | | Original | | | |
| Sho-Ki (Game Disc) 將姫 | PC | | Original | | | |
| Sho-Ki (Animation Disc) 將姫 | PC | | Original | | | |
| Shock Price 500 Game Series: Cankeri: Kick Kick Kick SHOCK PRICE 500 GAME SERIES 缶蹴り~KICKKICKKICK~ | PC | | Original | | SRRW 69 | |
| Shock Price 500 Game Series: Chu-Chu Tataki SHOCK PRICE 500 GAME SERIES チュウチュウたたき | PC | | Original | | SSRX 3016 | |
| Shock Price 500 Game Series: Dasshutsu! SHOCK PRICE 500 GAME SERIES 脱出! | PC | | Rerelease | | SSRX 3029 | |
| Shock Price 500 Game Series: Dasshutsu! SHOCK PRICE 500 GAME SERIES 脱出! | PC | | Original | | SSRX 3029 | |
| Shock Price 500 Game Series: Digital Puzzle Street: Blue SHOCK PRICE 500 GAME SERIES デジタル・パズル・ストリート Blue | PC | | Original | | SSRX 3078 | |
| Shock Price 500 Game Series: Doki-Doki Mouse SHOCK PRICE 500 GAME SERIES ドキドキマウス | PC | | Original | | SSRX 3011 | |
| Shock Price 500 Game Series: Doki-Doki Mouse SHOCK PRICE 500 GAME SERIES ドキドキマウス | PC | | Original | | SSRX 3011 | |
| Shock Price 500 Game Series: Go Fish SHOCK PRICE 500 GAME SERIES ゴーフィッシュ | PC | | Original | | SSRX 3005 | |
| Shock Price 500 Game Series: Golf: Challenge at Mauna Lani Resort SHOCK PRICE 500 GAME SERIES ゴルフ チャレンジ アット マウナラニリゾート | PC | | Rerelease | | SSRX 3072 | |
| Shock Price 500 Game Series: Gomoku Narabe SHOCK PRICE 500 GAME SERIES 五目ならべ | PC | | Original | | SSRX 3012 | |
| Shock Price 500 Game Series: Hit the Block SHOCK PRICE 500 GAME SERIES ヒット・ザ・ブロック | PC | | Rerelease | | SSRX 3018 | |
| Shock Price 500 Game Series: Mahjong II SHOCK PRICE 500 GAME SERIES 麻雀Ⅱ | PC | | Original | | SSRX 3026 | |
| Shock Price 500 Game Series: Reversi SHOCK PRICE 500 GAME SERIES リバーシ | PC | | Original | | SSRX 3004 | |
| Shock Price 500 Game Series: Shooting Machine SHOCK PRICE 500 GAME SERIES シューティングマシーン | PC | | Original | | SSRX 3010 | |
| Shock Price 500 Game Series: Shougi SHOCK PRICE 500 GAME SERIES 将棋 | PC | | Original | | SSRX 3027 | |
| Shock Price 500 Game Series: Slot Machine SHOCK PRICE 500 GAME SERIES スロットマシーン | PC | | Original | | SSRX 3007 | |
| Shock Price 500 Game Series: Smash Hockey SHOCK PRICE 500 GAME SERIES スマッシュホッケー | PC | | Original | | SSRX 3084 | |
| Shock Price 500 Game Series: Space Hockey SHOCK PRICE 500 GAME SERIES スペースホッケー | PC | | Original | | SSRX 3019 | |
| Shock Price 500 Game Series: The Room SHOCK PRICE 500 GAME SERIES ザ・ルーム | PC | | Original | | SSRX 3050 | |
| Shock Price 500 Game Series: Volleyball SHOCK PRICE 500 GAME SERIES バレーボール | PC | | Original | | SSRW 30032 | |
| Shock Price Advance Series: Othello SHOCK PRICE ADVANCE SERIES オセロ | PC | | Original | | SSRW 30054 | |
| Shock Wave 지구공습 2019 | 3DO | | Original | | GDT-GA 101 | |
| Shock Wave: Operation JumpGate ショック・ウェーブ ~オペレーション・ジャンプゲート~ | 3DO | | Demo-CD | | FZ-JJ9DSV-5D | |
| Shock Wave: Operation JumpGate ショック・ウェーブ ~オペレーション・ジャンプゲート~ | PSX | | Original | | SLPS 00516 | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Shockwave Assault | PC | | Original | | E354WCED | |
| Shodai Xbox Game Gokansei Update Disc: 2007-nen 7-gatsuban 初代 Xbox ゲーム互換性アップデート ディスク (2007 年 7 月版) | XBOX360 | | Bundled with Halo History Pack | | | |
| Shogo: Mobile Armor Division | PC | | TF1 Video Multimedia | | | |
| Shogun: Total War (Sneak Preview) | PC | | | | EAX08901965DD | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | EAE088019651D | |
| Shogun: Total War (Disc 2) | PC | | Rerelease | | EAE088019651D2 | |
| Shogun: Total War (Disc 1) | PC | | Original | | EAG08801965D1 | |
| Shogun: Total War (Disc 2) | PC | | Original | | EAG08801965D2 | |
| Shogun: Total War (Manuale in formato PDF) | PC | | | | ZMAECA471SA | |
| Shogun: Total War (Disc 1) ショーグン トータル ウォー | PC | | Original | | EMW-4070 | |
| Shogun: Total War (Disc 2) ショーグン トータル ウォー | PC | | Original | | EMW-4070 | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | 798727 | |
| Shogun: Total War: The Mongol Invasion | PC | | Original | | EAD08803486D | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | | Original | | EAD08803525D | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | | Original | | EAD08803525D1 | |
| Shoot the Bullet for Busy Person. Tengu Without Increased Scarlet Devil Mansion 忙しい人のための文花帖 ~紅魔館マシマシ天狗ヌキ~ | PC | | Original | | KSG-0005 | |
| Shooting Gallery | PALM | | Original | | | |
| Shooting Towns シューティング・タウンズ | FMT | | Original | | HMB-118 | |
| Shorelines | CDI | | | | | |
| Shougi Database Kiyuu 将棋データベース 棋友 | PCE | | Original | | STCD5001 | |
| Shougi Joryuu Meijin'isen 将棋 女流名人位戦 | PSX | | Original | | SLPS 00139 | |
| Shougi Saikyou 2 将棋最強2 | PSX | | Original | | SLPM 86069 | |
| Shougi Saikyou: Pro ni Manabu 将棋最強 プロに学ぶ | PSX | | Original | | SLPS 01976 | |
| Shouhin Catalog CD-ROM 2002 Shoka Version: Illusion 商品カタログCD-ROM 2002初夏バージョン Illusion | PC | | | | | |
| Shoujo Kakumei Utena: La Maison de Chu Chu 少女革命ウテナ メゾン・ド・チュチュ | PC | | Original | | KIRA 19 | |
| Shoukansha 召喚者 | PC | | Original | | | |
| Shouryuu Senki Tenmu (Taikenban and Yokoku Movie) 昇竜戦姫 天夢 体験版&予告ムービー | PC | | Demo | | | |
| Showcase Pool: UK Style | PC | | | | | |
| Showcase Snooker | PC | | Original | | | |
| Shrek 2 | PC | | Original | | 32585.101.GM | |
| Shrek 2 | PC | | Original | | 32585.101.SW | |
| Shrek 2 | MAC | | Original | | 10700-1CDA | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shrek 2 (Final Press Kit) | PC | | Press Kit | | | |
| Shrek 2 | PC | | | | 32585.101.US | |
| Shrek 2 Activity Centre: Twisted Fairy Tale Fun | PC | | Original | | 31917.101.UK | |
| Shrek 2: Team Action | PC | | Original | | 32789.101.GM | |
| Shrek der Dritte: Die Suche nach Arthus | VFLASH | | Original | | 093144(GER) | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek Le Troisième: En quête d'Artur | VFLASH | | Original | | 093145(FR) | |
| Shrek Swamp Fun with Early Math | PC | | | | 30993.101.AU | |
| Shrek Tercero: ¿Dónde Está Arturo? | VFLASH | | Original | | 093147(SP) | |
| Shrek the Third: The Search for Arthur | VFLASH | | Original | | 093143(UK) | |
| Shrek: Centr razvlechenij Шрэк: Центр развлечений | PC | | Original | | | |
| Shrine Circus Tycoon | PC | | | | 31933.101.US | |
| Shtyrlic Штырлиц | PC | | Original | | | |
| Shtyrlic 2: Tango v pampasah Штырлиц 2: Танго в пампасах | PC | | Original | | | |
| Shtyrlitc: Otkrytie Ameriki (Disc 1) Штырлитц: Открытие Америки | PC | | 1C: Kollekciya igrushek | | | |
| Shtyrlitc: Otkrytie Ameriki (Disc 2) Штырлитц: Открытие Америки | PC | | 1C: Kollekciya igrushek | | | |
| Shuffle15 | PC | | Covermount | | | |
| Shuihu Yingxiong Zhuan: Huo Zhi Hun 水滸英雄传:火之魂 | PC | | Original | | | |
| Shuppoppo II しゅっぽっぽ Ⅱ | PC | | | | WIC-5343 | |
| Shura no Mon 修羅の門 | PSX | | Original | | SLPS 01202 | |
| Shusse Mahjong Daisettai 出世麻雀 大接待 | PSX | | Original | | SLPS 00276 | |
| Shutter Island Shutter Island: The Adventure Game | PC | | Original | | | |