Region | Title | System | Version | Edition | Languages | Serial | Status |
| Reader Rabbit 2 Deluxe! | PC | 1.1 | Original | | 59390-CD | |
| Reader Rabbit Personalized 2nd Grade: 2nd Grade Learning Adventure | PC | 2.0 | | | RSG744CE-CD | |
| Reader Rabbit: 2nd Grade | PC | 1.1 | Rerelease | | 381490-CD | |
| Reader Rabbit: Thinking Adventures: Ages 4-6 | PC | 1.1 | Original | | 381425-CD | |
| Realms of Arkania III: Shadows over Riva | PC | 1.01 | Realms of Arkania Trilogy | | | |
| Rescue Heroes: Meteor Madness | PC | 1.0c | Original | | S7127310 | |
| Resident Evil 4 | PC | 1.0 | Original | | 683117-DVD | |
| Richard Scarry's Busytown: Best Reading Program Ever | PC | | Rerelease | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0 | Original | | | |
| Riven: The Sequel to Myst (Disc 2) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-2 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-4 | |
| Road & Track Presents: The Need for Speed SE | PC | | CD-ROM Classics, Rerelease | | 5936, 1162107 | |
| Road Rash | PC | 1.0A | CD-ROM Classics | | 5995 | |
| RollerCoaster Tycoon 2 | PC | | Rerelease, RollerCoaster Tycoon 2 Pack | | BIPRLRCT2CDRV1 | |
| RollerCoaster Tycoon 2: Triple Thrill Pack | PC | | Original | | Part # 25803CD | |