Region | Title | System | Version | Edition | Languages | Serial | Status |
| Agon: The Mysterious Codex | PC | 1.0 | Original | | | |
| Amazing Hidden Object Games 3 Pack: Paranormal Mysteries | PC | | Original | | | |
| Ankh: The Tales of Mystery | ARCH | 1.0 | Original | | | |
| The Beast Within: A Gabriel Knight Mystery (Disc 1) | PC | 1.1 | Original, Game of the Year | | S238410, S4600220Z12ZZ | |
| The Beast Within: A Gabriel Knight Mystery (Disc 2) | PC | 1.1 | Original, Game of the Year | | S238420, S4600220Z1201 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 3) | PC | 1.1 | Original, Game of the Year | | S238430, S4600220Z1202 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 4) | PC | 1.1 | Original, Game of the Year | | S238440, S4600220Z1203 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 5) | PC | 1.1 | Original, Game of the Year | | S238450, S4600220Z1204 | |
| The Beast Within: A Gabriel Knight Mystery (Disc 6) | PC | 1.1 | Original, Game of the Year | | S238460, S4600220Z1205 | |
| Bionicle: Mysteries of Metru Nui | PC | 1.0 | Bundled with LEGO Toa Metru: Whenua | | 4225395 | |
| Castle: Never Judge a Book by Its Cover Castle: Hidden Object Mystery Game | PC | 1.0 | | | 41890-DVD, 41890-DVD v1.0 | |
| Cluedo: The Mystery Continues | CDI | 1.04 | Original | | 819 1038 | |
| The ClueFinders: Mystery Mansion Arcade | PC | 1.1 | Deluxe 2CD Set | | ARCADESS-CD2 | |
| Detective Barbie: Mystery of the Carnival Caper | PC | 1.0 | Original | | 20461-0919 | |
| Detective Barbie: The Mystery Cruise | PSX | | Original | | SLES-03803 | |
| Detective Barbie: The Mystery Cruise | PSX | | Original | | SLUS-01221 | |
| Disney Guilty Party: Mystery Fun for Everyone! | WII | | Original | | RVL-SGUE-USA-B0 | |
| Dungeons & Dragons: Mystara Eiyuu Senki ダンジョンズ&ドラゴンズ -ミスタラ英雄戦記- | PS3 | 01.01 | Original, Limited Edition | | BLJM 61055 | |
| Fear for Sale: Mystery of Melnroy Manor | PC | | Collector's Edition | | 33381010US | |
| Freddi Fish 2: Het Mysterie van de Spoken op School | PC | | Original | | | |
| The Game Series 48: Adventure Game: Mysterious House ザ・ゲームシリーズ48 アドベンチャーゲーム ミステリアスハウス | PC | | Original | | DGS-48 | |
| Hidden Mysteries: The Fateful Voyage: Titanic / Hollywood: The Director's Cut Hidden Mysteries: Titanic / Lost Secrets: Hollywood Mysteries | PC | | Original | | | |
| Hidden Mysteries: Titanic | WII | | Original | | RVL-STTE-USA-B0, RVL-STTE-USA-B1 | |
| Hidden Mysteries: Vampire Secrets / Lost Secrets: A Vampire's Tale: Paris Stories | PC | | Original | | | |
| I Spy Mystery | PC | | Scholastic | | P/N: CDR 9-90060-3 | |
| Inspector Parker Mystery Bundle | PC | 1.0.2.2624 | Original | | 1030-10292 | |
| Jewel Quest Mysteries: Curse of the Emerald Tear | PC | | Original | | | |
| JumpStart Adventures 3rd Grade: Mystery Mountain | PC | 1.2.0 | Rerelease | | S0378011 | |
| Lost Secrets: Vatican Mysteries / Lost Secrets: Bermuda Triangle | PC | | Original | | | |
| Macabre Mysteries: Curse of the Nightingale | PC | | Collector's Edition | | 33400010US | |
| Mary-Kate and Ashley: Magical Mystery Mall | PSX | | Original | | SLUS-01121 | |
| Matikka Raketti Mysteerio | PC | 1.0.0.1 | Original, Rerelease | | | |
| Midnight Mysteries: Devil on the Mississippi | PC | | Collector's Edition | | | |
| Midnight Mysteries: Salem Witch Trials | PC | | Original | | | |
| Myst | PSX | | Original, Help Charity Compilation | | SLES-00218 | |
| Myst | PC | 1.0.3 | Original | | RBB0176CDE | |
| Myst | PSP | 1.02 | Original | | ULES-00412 | |
| Myst | CDI | 1.10 | Original | | 810 0308 | |
| Myst | SS | 1.100 | Original | | MK81081-50 | |
| Myst | ACD | | Original | | | |
| Myst | 3DO | | Original | | FZ-SG0204 | |
| Myst | PC | 1.0.3 | Original | | RBB0176CDG | |
| Myst ミスト | 3DO | | Original | | FZ-SJ0204 | |
| Myst ミスト | SS | 1.050 | Original | | T-1501G | |
| Myst ミスト | MAC | 1.0J | Original | | IP-026 | |
| Myst ミスト | PC | 1.3 | Rerelease | | IP-12201 | |
| Myst ミスト | PSX | Rev 2 | Winter Campaign, PlayStation the Best, PlayStation the Best Reprint, Value 1500 | | SLPS 00024 … | |
| Myst | AJCD | | Original | | J9069E | |
| Myst | AJCD | | Bundled with Atari Jaguar CD (Demo) | | | |
| Myst | AJCD | | Bundled with Atari Jaguar CD (Demo) | | | |
| Myst | 3DO | | Original | | FZ-SM0204 | |
| Myst | PSX | | Original | | SCUS-94602 | |
| Myst | PC | 1.0 | Original | | | |
| Myst | SS | 1.001 | Original | | T-8101H | |
| Myst | PC | 1.1 | Original | | | |
| Myst | PC | 1.3 | Ages of Myst: Fifth Anniversary Commemorative Edition | | 1820211B | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3 | Rerelease | | | |
| Myst | PC | 1.3.1 | Original, Ages of Myst, Bundle, Rerelease | | 1820220I | |
| Myst | MAC | | Original | | RBB0175CDE | |
| Myst | PC | 1.0.1 | Original | | B5845CXD | |
| Myst Antologia | PC | | Kolekcja Klasyki | | CENEGA 407/PCDVD-ROM/2006 | |
| Myst III: Exile | PC | | Myst: The Collection, Covermount | | 5005053 | |
| Myst III: Exile | XBOX | | Original | | US-017 | |
| Myst III: Exile | PS2 | 1.02 | Original | | SLES-50726 | |
| Myst III: Exile (Disc 1) | PC | 1.2 | Original, Collector's Edition | | | |
| Myst III: Exile (Disc 2) | PC | 1.2 | Original, Collector's Edition, The Games Collection, Xtreme | | | |
| Myst III: Exile (Disc 3) | PC | 1.2 | Original, Collector's Edition, Xtreme | | | |
| Myst III: Exile (Disc 4) | PC | 1.2 | Original, Collector's Edition, Xtreme | | | |
| Myst III: Exile (Disc 1) | PC | 1.2 | Original, Myst: Die Trilogie | | | |
| Myst III: Exile (Disc 2) | PC | 1.2 | Original, Myst: Die Trilogie | | | |
| Myst III: Exile (Disc 3) | PC | 1.2 | Original, Myst: Die Trilogie | | | |
| Myst III: Exile (Disc 4) | PC | 1.2 | Original, Myst: Die Trilogie | | | |
| Myst III: Exile ミストⅢ エグザイル | XBOX | | Original, Premium Box | | MP-001 | |
| Myst III: Exile (Disc 1) ミストⅢ エグザイル | PC | 1.24J (174) | Rerelease | | KUD-0008 | |
| Myst III: Exile (Disc 2) ミストⅢ エグザイル | PC | 1.24J (174) | Rerelease | | KUD-0008 | |
| Myst III: Exile (Disc 3) ミストⅢ エグザイル | PC | 1.24J (174) | Rerelease | | KUD-0008 | |
| Myst III: Exile (Disc 4) ミストⅢ エグザイル | PC | 1.24J (174) | Rerelease | | KUD-0008 | |
| Myst III: Exile | PS2 | 1.01 | Original | | SLUS 20434 | |
| Myst III: Exile | PC | 1.27 | Limited Edition, 10th Anniversary DVD Edition, Myst IV: Revelation Limited Edition | | 651116-DVD3 | |
| Myst III: Exile (Disc 1) | PC | 1.0 | Original | | 610427-CD1 | |
| Myst III: Exile (Disc 1) | PC | 1.2 | Original, Rerelease | | 610427-CD1A, 650331-CD1 | |
| Myst III: Exile (Disc 2) | PC | 1.2 | Original, Rerelease | | 610427-CD2A, 650331-CD2 | |
| Myst III: Exile (Disc 3) | PC | 1.2 | Original, Rerelease | | 610427-CD3A, 650331-CD3 | |
| Myst III: Exile (Disc 4) | PC | 1.2 | Original, Rerelease | | 610427-CD4A, 650331-CD4 | |
| Myst III: Exile (Disc 2) 神秘岛III:放逐 | PC | 1.0 | Original | | 610427-CD2 | |
| Myst III: Exile (Disc 3) 神秘岛III:放逐 | PC | 1.0 | Original | | 610427-CD3 | |
| Myst III: Exile (Disc 4) 神秘岛III:放逐 | PC | 1.0 | Original | | 610427-CD4 | |
| Myst III: Exile: Making of | PC | | Original | | | |
| Myst IV: Revelation (Disc 1) | PC | | Original, Limited Edition, Myst: The Collection, Ubisoft eXclusive | | 5004445-1, 681632-DVD1 | |
| Myst IV: Revelation (Disc 2) | PC | | Original, Limited Edition, Myst: The Collection, Ubisoft eXclusive | | 5004445-2, 681632-DVD2 | |
| Myst V: End of Ages (Disc 1) | PC | | Original | | 682523-CD1 | |
| Myst V: End of Ages (Disc 2) | PC | | Original | | 682523-CD2 | |
| Myst V: End of Ages (Disc 3) | PC | | Original | | 682523-CD3 | |
| Myst: Masterpiece Edition | PC | | Rerelease, Covermount, Myst: The Collection | | 2234818 | |
| Myst: Masterpiece Edition | PC | 1.0 | Myst: Die Trilogie | | 40682-CD | |
| Myst: Masterpiece Edition | MAC | 1.0 | Myst: Die Trilogie | | 40682-CD | |
| Myst: Masterpiece Edition | PC | 1.0 | Rerelease | | | |
| Myst: Masterpiece Edition | PC | 1.0 | Original | | 054761-CD | |
| Myst: Masterpiece Edition | PC | 1.0 | Original | | 054761-CD | |
| Myst: Masterpiece Edition | PC | 1.0 | 10th Anniversary DVD Edition | | 651116-DVD1 | |
| Mystaria: The Realms of Lore | SS | 1.000 | Original | | MK81300-50 | |
| Mystereet Portable: Yasogami Kaoru no Chousen! ミステリート ポータブル ~八十神かおるの挑戦!~ | PSP | 1.01 | Original | | ULJM 05328 | |
| Mysterious Adventures: 6-Pack Mysterious Adventures: 6 Complete Games! | PC | | Original | | P/N: 127507 | |
| Mysterious Journey II (Disc 1) | PC | DPV 1.1 | Original | | PCO399CD | |
| Mysterious Journey II (Disc 2) | PC | DPV 1.1 | Original | | PCO339CD | |
| Mysterious Journey II (Disc 3) | PC | DPV 1.1 | Original | | PCO399CD | |
| Mysterious Song | PCE | | Unlicensed (Rerelease) | | FCD0001 | |
| Mysterious Song | PCE | | Unlicensed | | FCD0001 | |
| Mystery 4 Pack | PC | | Original | | | |
| Mystery 5 Collection (Disc 1) | PC | ARV 1.0 | Original | | DVD769CD | |
| Mystery 5 Collection (Disc 2) | PC | ARV 1.0 | Original | | | |
| Mystery Adventure Pack (Disc 2) | PC | | Original | | 1000-10805_CD2 | |
| The Mystery at Greveholm 2: Journey to Planutus Mysteriet på Greveholm 2: Resan till Planutus | PC | 1.01 | Original, Världens Bästa Julkalendrar | | 904065C | |
| The Mystery at Greveholm | PC | 1.12 | Världens Bästa Julkalendrar, Marshall Media | | 902000C | |
| Mystery Case Files: 13th Skull | PC | | Collector's Edition | | 33363101US | |
| Mystery Case Files: Dire Grove | PC | | Collector's Edition | | 35789.101.US | |
| Mystery Case Files: Ravenhearst | PC | | Rerelease | | 35419.101.US | |
| Mystery Case Files: Return to Ravenhearst | PC | 1.0.0.0 | Original | | 35743.101.US | |
| Mystery Case Files: The Malgrave Incident | WII | | Original | | RVL-SFIP-EUR-B0 | |
| Mystery Legends: Sleepy Hollow | PC | 1.01 | Original | | 02-5602-10 | |
| Mystery Legends: The Phantom of the Opera | PC | | Collector's Edition | | 33383010US | |
| Mystery Masters Volume 2 | PC | | Original | | | |
| Mystery of Mortlake Mansion: 3 Game Pack | PC | | Cosmi | | CDR176D1, SJ032011 | |
| The Mystery of the Druids (Disc 1) (Installation CD) | PC | 1.0.2.26 | Original | | CDR7045/UK2 | |
| The Mystery of the Druids (Disc 2) (The Present) | PC | 1.0.2.26 | Original | | CDR7045/UK2 | |
| The Mystery of the Druids (Disc 3) (The Past) | PC | 1.0.2.26 | Original | | CDR7045/UK2 | |
| The Mystery of the Druids (The Present) | PC | 1.0.2.26 | Original | | CDR7045/US2 | |
| The Mystery of the Mummy | PC | 1.0 | Original | | PC39020CD DPV1.0 | |
| Mystery P.I.: The Lottery Ticket | PC | 1.0.0.5 | Rerelease | | 0227 12/08 08-00124 | |
| Mystery P.I.: The New York Fortune | PC | | Original | | MPNY-09-00167 8/09 09-00256 | |
| Mystery P.I.: The Vegas Heist | PC | 1.0.0.3 | Original | | 0136 12/08 08-00143 | |
| Mystery Solitaire: Secret Island Mystery Quest: Secret Island | PC | 1.0.0.9 | Original | | | |
| The Mystery Team | PSP | 1.00 | Original | | UCES-01536 … | |
| Mystic Ark: Maboroshi Gekijou ミスティック・アーク ~まぼろし劇場~ | PSX | | Original | | SLPM 86147 | |
| The Mystic Dragoons ミスティックドラグーン | PSX | | Original, Shokai Genteiban, Xing Maruan Series 6 | | SLPS 02072 … | |
| Mystic Formula ミスティック・フォーミュラ | PCE | | Original | | MCCD 3004 | |
| Mystic Heroes | GC | | Original | | DL-DOL-GBHD-NOE | |
| Mystic House | PC | 1.0 | Game-Pack | | 80101 | |
| Mystic Midway: Phantom Express | CDI | | Original | | 810 0056, 810 0178 | |
| Mystic Midway: Phantom Express | CDI | | Original, Demonstration Disc | | 310-690-247-2, 310690247-2 | |
| Mystic Midway: Rest in Pieces | CDI | | Original, Demonstration Disc | | 310-690-152-2, 310690152-2, 690 152-2, 810 0021 | |
| Nancy Drew: Curse of Blackmoor Manor The 3D Adventures of Nancy Drew: Mystery 11: Curse of Blackmoor Manor | PC | 1.0 | Original | | 26051CD | |
| Nancy Drew: Last Train to Blue Moon Canyon (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #13: Last Train to Blue Moon Canyon | PC | 1.0 | Nancy Drew: Ultimate Dare | | 26742CD1, 26742CD1A | |
| Nancy Drew: Last Train to Blue Moon Canyon (Disc 2) (Data CD) Nancy Drew: Mystery #13: Last Train to Blue Moon Canyon | PC | 1.0 | Nancy Drew: Ultimate Dare | | 26742CD2, 26742CD2A | |
| Nancy Drew: Legend of the Crystal Skull (Disc 2) (Data CD) Nancy Drew: Mystery #17: Legend of the Crystal Skull | PC | 1.1 | Original | | HER00065-1.2 | |
| Nancy Drew: Secret of the Scarlet Hand Nancy Drew: Mystery 6: Secret of the Scarlet Hand | PC | 1.0a | Original | | 24451CD1A | |
| Nancy Drew: The Creature of Kapu Cave (Disc 1) (Install/Play Game CD) Nancy Drew: Mystery #15: The Creature of Kapu Cave | PC | 1.0 | Original, Nancy Drew: Double Dare 5 | | HER00062-1.1 | |
| Nancy Drew: The Creature of Kapu Cave (Disc 2) (Data CD) Nancy Drew: Mystery #15: The Creature of Kapu Cave | PC | 1.0 | Original, Nancy Drew: Double Dare 5 | | HER00062-1.2 | |
| Nancy Drew: The Final Scene Nancy Drew: Mystery #5: The Final Scene | PC | 1.0 | Original | | PCO337CD | |
| Nancy Drew: The White Wolf of Icicle Creek (Disc 2) (Data CD) Nancy Drew: Mystery #16: The White Wolf of Icicle Creek | PC | 1.0 | Original | | HER00063-1.2 | |
| Nightfall Mysteries: Fright Pack | PC | 1.0 | Original | | 02-1658-10 | |
| Nishimura Kyoutarou Mystery: Hokutosei no Onna 西村京太郎ミステリー 北斗星の女 | PCE | | Original | | NXCD9001 | |
| Nishimura Kyoutarou Travel Mystery: Akugyaku no Kisetsu: Tokyo Nanki Shirahama Renzoku Satsujin Jiken (Disc 1) 西村京太郎トラベル・ミステリー 悪逆の季節 東京~南紀白浜連続殺人事件 | 3DO | | Original | | FZ-SJ0403-A | |
| Nishimura Kyoutarou Travel Mystery: Akugyaku no Kisetsu: Tokyo Nanki Shirahama Renzoku Satsujin Jiken (Disc 2) 西村京太郎トラベル・ミステリー 悪逆の季節 東京~南紀白浜連続殺人事件 | 3DO | | Original | | FZ-SJ0403-B | |
| Paris 1313: The Mystery of Notre Dame Cathedral | PC | 0.1.2.1 | Original | | PRS003-CD | |
| ProSieben Mystery: Der vergessene Gott (Disc 1) | PC | | Original | | | |
| ProSieben Mystery: Der vergessene Gott (Disc 2) | PC | | Original | | | |
| ProSieben Mystery: Der vergessene Gott (Disc 3) | PC | | Original | | | |
| The Quaddle Family Mysteries 1: The Case of the Scarce Scarab: Lobby / Kitchen | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 3: The Case of the Scarce Scarab: Parlor / Family Room | PC | 2.0 | Original | | | |
| The Quaddle Family Mysteries 1: The Case of the Scarce Scarab: Lobby / Kitchen | PSX | | Original | | LSP-060101 … | |
| The Quaddle Family Mysteries 2: The Case of the Scarce Scarab: Garden | PSX | | Original | | LSP-060102 … | |
| The Quaddle Family Mysteries 3: The Case of the Scarce Scarab: Parlor / Family Room | PSX | | Original | | LSP-060103 … | |
| R?MJ: The Mystery Hospital エムジェイ。 -THE MYSTERY HOSPITAL- | SS | 1.000 | Original | | T-13322G | |
| R?MJ: The Mystery Hospital (Disc 1) (What's Going On) R?エムジェイ The Mystery Hospital | PSX | | Original, PlayStation the Best | | SLPS 01087 … | |
| R?MJ: The Mystery Hospital (Disc 2) (Fears Behind) R?エムジェイ The Mystery Hospital | PSX | | Original, PlayStation the Best | | SLPS 01088 … | |
| R?MJ: The Mystery Hospital: Second Attack Sample CD-ROM | PSX | | Taikenban | | SLPM 80172 | |
| realMyst | PC | 1.0 | Original | | 380711-CD | |
| Return to Mysterious Island (Disc 1) | PC | 1.0 | Original | | PCO422CD | |
| Return to Mysterious Island (Disc 2) | PC | 1.0 | Original | | PCO422CD | |
| Rise of the Dragon: A Blade Hunter Mystery ライズ・オブ・ザ・ドラゴン ~ブレイド・ハンター・ミステリー~ | MCD | | Original | | G-6002 | |
| Riven: A Sequência de Myst (Disc 1) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 2) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 3) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: A Sequência de Myst (Disc 4) | SS | 1.000 | Original | | 191546, MK-81801-45 | |
| Riven: The Sequel to Myst (Disc 1) | PC | | Original | | | |
| Riven: The Sequel to Myst (Disc 1) | PSX | | Original | | SLES-00963 | |
| Riven: The Sequel to Myst (Disc 1) | SS | 1.003 | Original | | MK81801-50 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.02 | Ubisoft eXclusive | | 2235208 | |
| Riven: The Sequel to Myst (Disc 2) | PSX | | Original | | SLES-10963 | |
| Riven: The Sequel to Myst (Disc 2) | SS | 1.003 | Original | | MK81801-50 | |
| Riven: The Sequel to Myst (Disc 3) | PSX | | Original | | SLES-20963 | |
| Riven: The Sequel to Myst (Disc 3) | SS | 1.003 | Original | | MK81801-50 | |
| Riven: The Sequel to Myst (Disc 4) | PSX | | Original | | SLES-30963 | |
| Riven: The Sequel to Myst (Disc 4) | SS | 1.003 | Original | | MK81801-50 | |
| Riven: The Sequel to Myst (Disc 5) | PSX | | Original | | SLES-40963 | |
| Riven: The Sequel to Myst (Disc 1) | PSX | | Original | | SLES-01100 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0GE | Myst: Die Trilogie | | | |
| Riven: The Sequel to Myst (Disc 2) | PC | 1.0GE | Original, Myst: Die Trilogie | | RBB7017CDG[2] | |
| Riven: The Sequel to Myst (Disc 3) | PSX | | Original | | SLES-21100 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.0GE | Original, Myst: Die Trilogie | | RBB7017CDG[3] | |
| Riven: The Sequel to Myst (Disc 4) | PSX | | Original | | SLES-31100 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.0GE | Original, Myst: Die Trilogie | | RBB7017CDG[4] | |
| Riven: The Sequel to Myst (Disc 5) | PSX | | Original | | SLES-41100 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.0GE | Original, Myst: Die Trilogie | | RBB7017CDG[5] | |
| Riven: The Sequel to Myst (Disc 1) リヴン ザ シークェル トゥー ミスト | PSX | | Original | | SLPS 01180 | |
| Riven: The Sequel to Myst (Disc 1) リヴン ザ シークェル トゥー ミスト | PC | 1.0J | Original | | CH7KA0200-1 | |
| Riven: The Sequel to Myst (Disc 2) リヴン ザ シークェル トゥー ミスト | PSX | | Original | | SLPS 01181 | |
| Riven: The Sequel to Myst (Disc 2) リヴン ザ シークェル トゥー ミスト | PC | 1.0J | Original | | CH7KA0200-2 | |
| Riven: The Sequel to Myst (Disc 3) リヴン ザ シークェル トゥー ミスト | PSX | | Original | | SLPS 01182 | |
| Riven: The Sequel to Myst (Disc 3) リヴン ザ シークェル トゥー ミスト | PC | 1.0J | Original | | CH7KA0200-3 | |
| Riven: The Sequel to Myst (Disc 4) リヴン ザ シークェル トゥー ミスト | PSX | | Original | | SLPS 01183 | |
| Riven: The Sequel to Myst (Disc 4) リヴン ザ シークェル トゥー ミスト | PC | 1.0J | Original | | CH7KA0200-4 | |
| Riven: The Sequel to Myst (Disc 5) リヴン ザ シークェル トゥー ミスト | PSX | | Original | | SLPS 01184 | |
| Riven: The Sequel to Myst (Disc 5) リヴン ザ シークェル トゥー ミスト | PC | 1.0J | Original | | CH7KA0200-5 | |
| Riven: The Sequel to Myst | PC | | Original | | | |
| Riven: The Sequel to Myst | PC | 1.2 | 10th Anniversary DVD Edition | | 651116-DVD2 | |
| Riven: The Sequel to Myst (Disc 1) | PSX | | Original | | SLUS-00535 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.0 | Original | | | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD1 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Original | | 1822115 | |
| Riven: The Sequel to Myst (Disc 2) | PSX | | Original | | SLUS-00563 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Rerelease, Ages of Myst | | 650324-CD2 | |
| Riven: The Sequel to Myst (Disc 3) | PSX | | Original | | SLUS-00564 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD3 | |
| Riven: The Sequel to Myst (Disc 4) | PC | | Original | | 1822117 | |
| Riven: The Sequel to Myst (Disc 4) | PSX | | Original | | SLUS-00565 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD4 | |
| Riven: The Sequel to Myst (Disc 5) | PC | | Original | | 1822118 | |
| Riven: The Sequel to Myst (Disc 5) | PSX | | Original | | SLUS-00580 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.0 | Original | | 1822118 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD5 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Original, Rerelease | | RBB7017CDE[2] | |
| Riven: The Sequel to Myst (Disc 2) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-2 | |
| Riven: The Sequel to Myst (Disc 3) | PC | | Original, Rerelease | | RBB7017CDE[3] | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-3 | |
| Riven: The Sequel to Myst (Disc 4) | PC | | Original, Rerelease | | RBB7017CDE[4] | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-4 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.02 | Original, The Games Collection, Myst: The Collection, Ubisoft eXclusive | | 2235208, 5005052-5 | |
| Sakura Taisen Monogatari: Mysterious Paris サクラ大戦物語 ~ミステリアス巴里~ | PS2 | 1.00 | Original | | SLPM 65515 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Scooby-Doo! Mystery Mayhem | PS2 | 1.01 | Original, Platinum: The Best of PlayStation 2 | | SLES-51883 … | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3E-USA | |
| Scooby-Doo! Mystery Mayhem | XBOX | | Original | | TQ-014 | |
| Simple 1500 Series Vol. 74: The Horror Mystery: Sangeki-kan: Kevin Hakushaku no Fukkatsu SIMPLE1500シリーズ Vol.74 THE ホラーミステリー 惨劇館 ~ケビン伯爵の復活~ | PSX | | Original | | SLPM 86901 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | | Original | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | | Original | | | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Dark Forces II: Ambush at Altyr 5 | PC | 1.0 | Demo: Bundle Version OEM | | 647030, CD-C95-990-E | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Original | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061833 | |
| Starshine Legacy: Episode 1: Mystery of the Soulriders | PC | | Original | | US-61-0603 04 | |
| Strange Cases: The Tarot Card Mystery / Strange Cases: The Lighthouse Mystery | PC | | The Best of Big Fish Games | | 33364101US | |
| Titanic Mystery | WII | | Original | | RVL-STME-USA-B0 | |
| Titanic: Ontrafel Het Mysterie | PC | 3.00 | Original | | | |
| Tokobot Plus: Mysteries of the Karakuri | PS2 | 1.01 | Original | | SLUS-21471 | |
| The Treasures of Mystery Island 2: The Gates of Fate | PC | | Original | | | |
| The Truth is Out There: Mystery Adventure Pack | PC | | Original | | UI-00743-01 | |
| Uru: Ages Beyond Myst | PC | | Original, OEM Bundle | | G71-URGA001 | |
| Uru: Ages Beyond Myst | PC | 1.0 | Original | | 651093-CD | |
| Vampire Mansion: A Linda Hyde Mystery | PC | | Collector's Edition | | | |
| Who Stole Hanukkah?! The Great Interactive Mystery Game מי גנב את חנוכה?! משחק הרפתקאות אינסראקסיבי | PC | | Original | | | |
| Yumemi Mystery Mansion | MCD | | Original | | 4430 | |