Region | Title | System | Version | Edition | Languages | Serial | Status |
| U-Move Super Sports | PS2 | 1.02 | Original | | SLES-52594 | |
| UEFA Challenge | PSX | | Original | | SLES-02806 | |
| UEFA Challenge | PS2 | 1.00 | Original | | SLES-50195 | |
| UEFA Champions League 2004-2005 | PS2 | 1.00 | Original | | SLES-52910 … | |
| UEFA Champions League: Season 2001/2002 | PS2 | 1.01 | Original | | SLES-50398 | |
| UFC: Ultimate Fighting Championship: Tapout | XBOX | | Original | | US-013 | |
| Ultima VIII: Pagan | PC | | CD-ROM Classics | | ORX05101284D | |
| Ultimate Mind Games | PS2 | 1.01 | Original | | SLES-51625 | |
| Ultimate Spider-Man | PS2 | 1.00 | Original | | SLES-53391 | |
| Ultimate Strategy Archives: Classic Strategy (Disc 1) | PC | | Original | | CD-ICD-825-E1 | |
| Ultimate Strategy Archives: Classic Strategy (Disc 2) Jagged Alliance: Deadly Games | PC | | Original | | CD-ICD-825-E2 | |
| Ultimate Strategy Archives: Classic Strategy (Disc 3) M.A.X.: Mechanized Assault & Exploration | PC | | Original | | CD-ICD-825-E3 | |
| Ultimate Strategy Archives: Classic Strategy (Disc 4) Dark Colony | PC | 1.0 | Original | | CD-ICD-825-E4 | |
| The Ultimate Wizardry Archives | PC | | Original | | CD-W95-895-E | |
| The Ultimate World Cup Quiz | PS2 | 1.01 | Original | | SLES-53600 | |
| Under a Killing Moon (Disc 2) | PC | | Original | | USG 001 - 2 | |
| Under a Killing Moon (Disc 3) | PC | | Original | | USG001 - 3 | |
| Under a Killing Moon (Disc 4) | PC | | Original | | USG001 - 4 | |
| Under the Skin | PS2 | 1.01 | Original | | SLES-52719 | |
| Universe at War: Earth Assault | PC | 1.0 (86418) | Original, Covermount | | SEGA-PC058 | |
| Unreal | PC | May 17 1998 | Original | | | |
| Unreal Mission Pack I: Return to Na Pali | PC | 100 | Original | | | |
| Unreal Tournament III | PC | 3487 | Original, Collector's Edition | | DVD-UT3-EU | |
| Urban Freestyle Soccer | XBOX | | Original | | AC-012 | |
| US Racer | PC | 1.0.0.21 | Original | | USRAC, USRACDE, USRACUK | |
| US Racer | PS2 | 1.02 | Original | | SLES-50939 | |
| Uncharted: Drake's Fortune | PS3 | 01.00 | Original, Essentials, Platinum: The Best of PlayStation 3 | | BCES-00065 … | |
| UEFA Euro 2004: Portugal | XBOX | | Original | | EA-074 | |
| Uli Stein Vol. 2: 3D Mahjongg | PC | | Original | | | |
| Ultima Online: Renaissance | PC | | Play the Games Vol. 3 | | | |
| Die Ungelösten Fälle von Sherlock Holmes: Das Geheimnis der Tätowierten Rose | PC | | Original, CD ROM Classics | | EAG05100305D | |
| Die Unglaublichen: The Incredibles: Der Angriff des Tunnelgräbers (Disc 1) Disney präsentiert einen Pixarfilm: Die Unglaublichen: The Incredibles: Der Angriff des Tunnelgräbers | PC | | Original | | 4005209066969 | |
| Unreal | PC | Jul 18 1998 | Bundle Version OEM | | P/N: 1713320718 | |
| Unreal II: The Awakening (Disc 1) (Install Disc) | PC | | Original | | U2APCD/DISC1 | |
| Unreal II: The Awakening (Disc 2) (Play Disc) | PC | | Original | | U2APCD/DISC2 | |
| Unreal Tournament 2004 (Play Disc) | PC | 3186 | Original | | 10183730A | |
| Uprising: Join or Die | PC | | Original | | | |
| Urlaubs Raser | PC | 1.00 | Jewel Case Budget | | URLAUBDE | |
| The Ultimate Doom | PC | 1.9 | Original | | 04-10333CD | |
| Unreal Tournament 2003 (Disc 1) | PC | 2107 | Original | | 1004250, Part# 23956CD1 | |
| Unreal Tournament 2003 (Disc 2) | PC | 2107 | Original | | 1007457, Part# 23956CD2 | |
| Unreal Tournament 2003 (Disc 3) | PC | 2107 | Original | | 1007459, Part# 23956CD3 | |
| Uru: Ages Beyond Myst | PC | 1.0 | Original | | 651093-CD | |
| Ultra Street Fighter IV ウルトラストリートファイターIV | XBOX360 | | Original | | CC-2044 | |