| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | S!Zone for SimCity 2000 | PC | | Original |  | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | S.C.A.R.S. | PC | 1.1 | Original |     | | |
 | S.C.A.R.S. | PC | 1.1 | Original | | | |
| S.T.A.L.K.E.R.: Call of Pripyat | PC | 1.6.02 | Original | | | |
| S.T.A.L.K.E.R.: Call of Pripyat | PC | 1.6.02 | Collector's Edition | | | |
| S.T.A.L.K.E.R.: Clear Sky
BGamer 168 | PC | 1.5.10 | Covermount | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | | Original, Radiation Edition | | | |
 | S.W.I.N.E. (PlayDisk)
猪兔大战 | PC | 1.2 | Original | | | |
 | S.W.I.N.E. (Disc 1)
猪兔大战 | PC | 1.2 | Original | | | |
 | S.W.I.N.E. (Disc 2)
Ś.W.I.N.I.A. | PC | | Original | | | |
 | Saban's Power Rangers: Time Force | PC | | Original | | | |
| The Saboteur | PC | 1.0 | Original | | | |
| Sabre Team | CD32 | | Original | | | |
| Sacred Plus (Disc 1) | PC | 1.8.30 | Original |   | | |
| Sacred Plus (Disc 2) | PC | 1.8.30 | Original | | | |
| Sacred: Underworld (Disc 1) | PC | 2.21 | Original | | | |
| Sacred: Underworld (Disc 2) | PC | 2.21 | Original | | | |
| Safecracker | PC | | Original |   | | |
 | Safecracker | PC | | Original, Gamez Classic / PC Zone Benelux Klassieker | | | |
| Sam & Max: Beyond Time and Space | PC | | Original | | | |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: The Devil's Playhouse
Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Samantha Swift and the Golden Touch
Samantha Swift Bundle | PC | | Original | | | |
| Samurai Shodown | 3DO | | Original | | | |
| The San Diego Zoo Presents... The Animals! | 3DO | | Original | | | |
| Sandwarriors: The Battle for the Sun Throne | PC | 1.0 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | 1.00.000 | Rerelease | | | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| SAS: Anti-Terror Force | PC | | | | | |
 | Satazius Next
サタゼウスネクスト | DC | 1.000 | Unlicensed | | | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
 | SBK 08: Superbike World Championship | PC | | Covermount | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| School Tycoon | PC | v1 | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorcher | PC | | Original | | | |
 | Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scratches | PC | | Original | | | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | Original, White Label | | | |
| Screamer | PC | | Screamer Injection | | | |
| Screamer | PC | | White Label | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer 4x4 | PC | | Covermount | | | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
 | Screamer Rally | PC | | Sold Out Software | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
| Search & Rescue 2 | PC | | Original | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Semper Fi | PC | | Original | | | |
| Sensible Golf | PC | | Original | | | |
| Sensible Soccer | MCD | | Bundled with Magazine (Playable Demo - Mega Power Disc 5, Demo) | | | |
| Sensible Soccer '98 | PC | | Original | | | |
| Sensible Soccer: European Club Edition | PC | | Original | | | |
| Sensible World of Soccer '96/'97 | PC | 2.0 | Original | | | |
| Serious Sam II | PC | | Sold Out Software | | | |
| Serious Sam II | PC | | Original | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | Covermount |  | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam: The First Encounter
英雄萨姆 | PC | 1.00 | Original, Zhima Kai Men | | | |
| Serious Sam: The First Encounter | PC | 1.00a | Original, TakeAdvantage |  | | |
| Serious Sam: The First Encounter | PC | 1.05 | Gold Edition | | | |
| Serious Sam: The First Encounter | PC | 1.00a | Software Pyramide | | | |
 | Serious Sam: The First Encounter
Крутой Сэм: Первая Кровь | PC | 1.00b | 1C: Kollekciya igrushek | | | |
 | Serious Sam: The First Encounter | PC | 1.00 | Original, Pack 5 Action Games | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original, TakeAdvantage | | | |
| Serious Sam: The Second Encounter | PC | 1.07 | Gold Edition, Covermount | | | |
| Serious Sam: The Second Encounter | PC | | Original, Rerelease | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
