| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Seek and Destroy
Seek & Destroy | PC | 1.0 | Original |  | J230D | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Seek and Destroy
Seek & Destroy | PC | | Original | | EPSAD01 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
 | The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge
The Monkey Island Bounty Pack: The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | 1.0 | LucasArts Classics: The Monkey Island Bounty Pack | | 3000012.101.UK | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| The Secret of Monkey Island | PC | 2.3 | Original, Bundle Version OEM |     | 2147010-590001 / I 042 | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| SeaWorld Adventure Parks Tycoon 2
SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| Search & Rescue 2 | PC | | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
 | Screamer Rally | PC | | Sold Out Software | | | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
 | Screamer 4x4 | PC | | Covermount | | | |
| Screamer 2
Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screamer 2 | PC | | Original | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer | PC | | White Label | | | |
| Screamer | PC | | Original, White Label | | | |
| Screamer | PC | | Screamer Injection | | | |
| Screamer | PC | | Original | | | |
| Scratches | PC | | Original | | | |
 | Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scrabble Interactive: 2003 Edition | PC | | Ubisoft eXclusive / Focus Essential |  | ESS493 | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble
Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble
Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble
Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scorcher | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0.1.8 | SoftKey | | SGW854BB, SGW854BB-CD | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0 | Original | | SGW844AB-CD | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
 | Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| Sci-Fi Pinball | PC | | Original | | | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| School Tycoon | PC | v1 | Original | | | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original, Bundle Version OEM | | 0297 Part No. 91323, 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage Warriors | PC | 1.0 | Megapak 4 | | 2205110-590001/1055SA | |
| SAS: Anti-Terror Force | PC | | | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 011143 | |
 | Santa Claus: Gold Edition | PC | | Original |   | PF5025 | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
 | Sanitarium (Disc 3) | PC | 1.01 | Original | | CS090738 | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | CD090736 | |
| Sanitarium (Disc 3) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 2) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.00.000 | Rerelease | | | |
| Sanitarium (Disc 2) | PC | 1.0 | Original | | CS090737 | |
| Sandwarriors: The Battle for the Sun Throne | PC | 1.0 | Original | | | |
| Sandwarriors | PC | 1.11 | Original | | CD-ICD-297-0 | |
| Samantha Swift and the Golden Touch
Samantha Swift Bundle | PC | | Original | | | |
| Sam & Max Hit the Road | PC | | Rerelease, The LucasArts Archives Vol. I | | 634430 | |
| Sam & Max Hit the Road | PC | 2.0 | LucasArts Classic | | 41117.101.UK | |
| Salt Lake 2002 | PC | 1.0 | Original | | MSALTPEN81 | |
| Safecracker | PC | | Original, Gamez Classic / PC Zone Benelux Klassieker | | | |
| Safecracker | PC | | Original |  | | |
 | The Saddle Club: Willowbrook Stables (Disc 2) (Play) | PC | | Original | | IRG-SCWB | |
| Sacrifice | PC | 0492.10.25 | Original | | CD-C95-1041-0, CD-C95-1041-E | |
| Sacrifice | PC | | Bundle Version MSI OEM | | CD-C951041-MSY4E | |
| Sacrifice | PC | | Bundle Version ASUS OEM | | CD-C951041-AS2E | |
| Sacred: Underworld (Disc 2) | PC | 2.21 | Original | | | |
| Sacred: Underworld (Disc 1) | PC | 2.21 | Original | | | |
| The Sacred Rings (Disc 4) | PC | 1.0 | Original | | PCO466CD | |
