Region | Title | System | Version | Edition | Languages | Serial | Status |
| Serial Experiments Lain (Disc 1) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01603 | |
| Serial Experiments Lain (Disc 2) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01604 | |
| Scooby-Doo! Unmasked | PS2 | 1.01 | Original | | SLES-53100 | |
| Soulcalibur III | PS2 | 2.00 | Original, Platinum, Platinum: The Best of PlayStation 2 | | SCES-53312 … | |
| Siren: Blood Curse | PS3 | 01.00 | Original | | BCES-00294 | |
| The Sly Collection | PS3 | 01.00 | Original | | BCUS-98246 | |
| Sly Cooper: Thieves in Time | PS3 | 01.02 | Original | | BCUS-98247 | |
| SOCOM: Special Forces | PS3 | 01.00 | Original | | BCES-00939 | |
| SOCOM: U.S. Navy SEALs: Confrontation | PS3 | 01.00 | Original | | BCUS-98183 | |
| Supercar Challenge | PS3 | 01.05 | Original | | BLES-00581 | |
| Star Wars: Battlefront II | PSP | 1.01 | Original, PSP Essentials, Platinum: The Best of PSP | | ULES-00183 … | |
| Scooby-Doo! Priklyucheniya v gorode prizrakov Скуби-Ду! Приключения в городе призраков | PC | | 1C: Igroteka | | | |
| Serious Sam: The First Encounter Крутой Сэм: Первая Кровь | PC | 1.00b | 1C: Kollekciya igrushek | | | |
| Serious Sam: The Second Encounter Крутой Сэм: Второе пришествие | PC | 1.05 | 1C: Kollekciya igrushek | | | |
| Shrek 2 Шрек 2 | PC | | 1C: Kollekciya igrushek | | | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.4 | Original | | MXX088003645D | |
| Soldat udachi II (Disc 1) Солдат удачи II | PC | 1.03 | Original | | | |
| Soldier of Fortune II: Double Helix (Disc 2) Солдат удачи II | PC | 1.03 | Gold Edition, Gold Edition (Best of Activision), 1C: Kollekciya igrushek | | 32313.102.UK, 32313.102.US | |
| Spider-Man 2 Человек-паук 2 | PC | | 1C: Kollekciya igrushek | | | |
| SpyHunter | PC | | Original | | 103201CDA, RUSSOBIT-M 2003/414 | |
| SRS: Street Racing Syndicate (Disc 1) | PC | | Original | | | |
| SRS: Street Racing Syndicate (Disc 2) | PC | | Original | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0000 | Original | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | 1.0001 | Original | | | |
| Saints Row: The Third (Disc 2) | PC | | Original | | P_40065_06A_PL | |
| Sanitary Podzemelij Санитары Подземелий | PC | | Original, 1C: Kollekciya igrushek | | | |
| Sid Meier's Civilization IV | PC | | 1C: Kollekciya igrushek | | | |
| Sid Meier's Civilization V: Brave New World Sid Meier's Civilization V: Дивный новый мир | PC | | Original | | 5061834/DVD | |
| The Sims 2: Seasons (Expansion Pack) The Sims 2: Времена года | PC | 1.7.0.145 | Original | | MXX07705518D, MXX07705518D/GER | |
| Sacred 2: Fallen Angel (Disc 1) Sacred 2: Падший ангел | PC | 2.0.2 build 1371 | Original | | | |
| Sacred 2: Fallen Angel (Disc 2) Sacred 2: Падший ангел | PC | | Original | | | |
| Saints Row: The Third (Disc 1) | PC | | Original | | P_40065_06A_PL | |
| The Sims 3: World Adventures The Sims 3: Мир Приключений | PC | | Original | | MXX09207028D | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Saints Row 2 | XBOX360 | | Original, Classics, Platinum Hits, Promo, Saints Row Double Pack | | TQ-2044 | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Soulcalibur IV ソウルキャリバーⅣ | XBOX360 | | Original, Classics, Promo, SoulCalibur IV / Tekken 6 | | NM-2016 | |
| Star Wars: The Force Unleashed II | XBOX360 | | Original, Platinum Hits | | LA-2034 | |
| Super Street Fighter IV スーパーストリートファイターIV | XBOX360 | | Original, Capcom Essentials, Collector's Package | | CC-2044 | |
| Shock Wave | 3DO | RE2 | Original, Not for Resale | | | |
| Starblade | 3DO | | Original, Not for Resale | | FZ-SE5351, FZ-SG5351 | |