| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Earthworm Jim: Special Edition | MCD | | Original |  | T-125045-50 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Earthworm Jim: Special Edition | MCD | | Original | | T-125045 | |
| Ecco the Dolphin | MCD | | Original, Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4408 | |
| Ecco: The Tides of Time | MCD | | Original |    | 4441-50 | |
| Eternal Champions: Challenge from the Dark Side | MCD | | Original | | 4427 | |
| Eternal Champions: Challenge from the Dark Side | MCD | | Original | | 4427 | |
 | Eberouge (Disc 1)
エーベルージュ | SS | 1.005 | Original |  | T-10309G | |
| Eberouge (Disc 2)
エーベルージュ | SS | 1.005 | Original | | T-10309G | |
| Eberouge Special: Koi to Mahou no Gakuen Seikatsu
エーベルージュ・スペシャル ～恋と魔法の学園生活～ | SS | 1.003 | Original | | T-10315G | |
| Enemy Zero (Disc 0) (Opening Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Enemy Zero (Disc 1) (Game Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Enemy Zero (Disc 1) (Game Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Enemy Zero (Disc 2) (Game Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Enemy Zero (Disc 3) (Game Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Enemy Zero (Disc 3) (Game Disc)
エネミー・ゼロ | SS | 1.000 | Original | | T-30001G | |
| Eternal Melody
エターナル・メロディ | SS | 1.002 | Original | | T-27802G | |
| Eve: The Lost One
イヴ・ザ・ロストワン | SS | 1.000 | Taikenban (Premium Pack, Eve: Burst Error & Desire Value Pack, Bundled with Book) | | 610-6837, T-15036G, T-15037G | |
| Eve: The Lost One (Disc 1) (Kyoko Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G, T-15041G | |
| Eve: The Lost One (Disc 2) (Snake Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G, T-15041G | |
| Eve: The Lost One (Disc 3) (Lost One Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G | |
| Eve: The Lost One (Disc 3) (Lost One Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G, T-15041G | |
| Eve: The Lost One (Disc 4) (Extra Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G | |
| Eve: The Lost One (Disc 4) (Extra Disc)
イヴ・ザ・ロストワン | SS | 1.000 | Original | | T-15035G, T-15041G | |
| EarthSiege 2
EarthSiege II | PC | 1.11 | Gold Games 2 (CD 2), Rerelease | | S4510210Z12Z1, S4510510Z12ZZ, S4520520Z12ZZ, SPI 046 | |
| EarthSiege 2 | PC | 1.1 | 3 Free | | W0735220 | |
| Earthworm Jim 2 | PC | | Earthworm Jim 1 & 2: The Whole Can O'Worms, Ubisoft Classique Collection | | | |
| Earthworm Jim: Special Edition | PC | 1.0 | Original, The Essential Collection |  | 1000142.101.UK, CDD-3114-101-3L | |
| Ecco the Dolphin | PC | | Original, Family Pack | | MK 85013-50, MK 85086-50 | |
| Ecco the Dolphin | PC | 1.1 | Original, Jack in the Box | | 85013 | |
| The Elder Scrolls Adventures: Redguard (Disc 2) (Play Disc) | PC | | Original | | | |
| Embrace
エンブレイス | PC | | Original | | | |
| Entomorph: Plague of the Darkfall
World of Aden: Entomorph: Plague of the Darkfall | PC | 1.0 | Awesome 4 Pak | | | |
| Eradicator | PC | 1.0 | Original | | | |
| Eradicator | PC | 1.0 | Original | | 5000-00445 | |
| The Even More! Incredible Machine | PC | 1.11 | Original | | 836354000 | |
| Exhumed | PC | 1.0 | Original | | 76896-421322 | |
| The Experiment (Disc 1) | PC | 1.0 | Original | | PCO548CD1 | |
| Extreme Assault | PC | | Original | | | |
 | Extreme Assault | PC | | Tanie Granie, eXtra Klasyka |  | | |
| Extreme-G 2 | PC | | Original | | | |
| Emerald Mines | CD32 | | Original | | | |
| Emit Vol. 1: Toki no Maigo
エミット Ｖｏｌ．１ 「時の迷子」 | FMT | | Demo | | HMF-904 | |
| Exciting CD (Disc 1)
エキサイティングＣＤ | FMT | | Hibaihin | | HMF-901 | |
| Exciting CD (Disc 2)
エキサイティングＣＤ | FMT | | Hibaihin | | HMF-902 | |
| eScape | CDI | | Original, Head Crash: Limited Edition Triple Pack | | 810 0117 | |
