Region | Title | System | Version | Edition | Languages | Serial | Status |
| S³: Silent Storm: Sentinels | PC | | Gold Edition | | ROSILENTST0004lab, ROSILENTST0006lab3 | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| The Settlers II: 10th Anniversary | PC | | Original | | 5004880 | |
| Shadow Man | PC | | Original | | CD194141.00-EUR | |
| Shadow of Memories | PC | | Original | | | |
| Sid Meier's Alpha Centauri | PC | | Original | | ORG08901524D | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.3 | |
| Sid Meier's Civilization IV: Colonization | PC | | Original | | 31491-1 | |
| Silver (Disc 1) | PC | | Original | | SILVCDR1DE | |
| The Sims 2: Fashion Stuff | PC | | Original | | MXX08005576D/ANZ | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | 1536607 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | MXX08006087D2 | |
| SnowCross | PC | | Original | | SNC001-CD | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | | Original | | SEGA-PC002-EU | |
| Soulbringer (Disc 1) | PC | | Original | | SOULBPCD/A1 | |
| Soulbringer (Disc 2) | PC | | Original | | SOULBPCD/A2 | |
| South Park | PC | | Original | | | |
| South Park | PC | | Original | | | |
| South Park Rally | PC | | Original | | CD194197.01-ENG | |
| Spore: Creature Creator | PC | | Original | | 1586407 | |
| Spy Kids 3-D: Game Over | PC | | Original | | I6100 | |
| Star Trek: Deep Space Nine: The Fallen | PC | | Original | | | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) | PC | | Original | | 3251830 | |
| Stirb Langsam: Nakatomi Plaza | PC | | Original | | S0025708 | |
| Streetwars: Constructor Underworld | PC | | Original | | strwapc52mult/a | |
| Stronghold 2 (Disc 2) (Play) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| Superbike World Championship | PC | | Original | | EAX08801929D | |
| SWAT 4 (Disc 1) | PC | | Gold Edition | | S1002638 | |
| SWAT 4: The Stetchkov Syndicate | PC | | Original | | S1003595 | |
| SWAT 4: The Stetchkov Syndicate | PC | | Original | | | |
| The Sims Carnival: SnapCity | PC | 0.029 | SimCity Box | | 1907347 | |
| Sub Command (Disc 1) Sub Command: Akula Seawolf 688(I) / 潛艇指揮官 | PC | 0.1.0.0 | Original | | 1430807 | |
| Sub Command (Disc 2) Sub Command: Akula Seawolf 688(I) / 潛艇指揮官 | PC | 0.1.0.0 | Original | | 1430817 | |
| Salt Lake 2002 | PC | 1.0 | Original | | MSALTPEN81 | |
| Severance: Blade of Darkness | PC | 1.0 | Original | | MSEVCDEU00, MSEVCDUK00 | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0 | Original | | 1015406 | |
| Silent Hill 2 (Disc 1) | PC | 1.0 | Original | | Part Number 23429/23435-1 | |
| Silent Hill 2: Director's Cut (Disc 1) | PC | 1.0 | Original | | F, G, I, S, SH2/CD/E | |
| Silent Hill 2: Director's Cut (Disc 2) | PC | 1.0 | Original | | F, G, I, S, SH2/CD/E | |
| Silent Hill 2: Director's Cut (Disc 3) | PC | 1.0 | Original | | F, G, I, S, SH2/CD/E | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | BestSeller Series | | S1001615 | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | Original | | S7213210 | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | 1.0 | Original | | 41121.101.GM | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3241830 | |
| Star Wars: Battlefront II (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3281830 | |
| Star Wars: Episodio I: Racer | PC | 1.0 | Original | | | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | PC | 1.0 | Original | | 9551830 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Spiel-CD) | PC | 1.0 | Original | | 41118.101.GM | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Spiel-CD) | PC | 1.0 | Original | | 41127.101.GM | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Rerelease | | 3261830R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3261830 | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) | PC | 1.0 | Original, LucasArts Classic | | 41123.101.IT, 41123.101.UK | |
| Star Wars: Republic Commando (Disc 1) (Spiel-CD) | PC | 1.0 | Original | | 41123.101.GM | |
| Stronghold 2 (Disc 2) (Play) FireFly Studios' Stronghold 2 | PC | 1.0 | Original | | | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 1) | PC | 1.0 | Original | | 11001-1CDA | |
| Schmidt Interaktivspass: Doppelkopf | PC | 1.0.0.0 | Original | | S0022421 | |
| Schmidt Interaktivspaß: Solitaire | PC | 1.0.0.0 | Original | | S0023093 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.0.0.0 | Original | | 3191830 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.0.0.0 | Original | | 3191830 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD2 | |
| Sid Meier's Railroads! | PC | 1.0.0.0 (58113) | Original | | | |
| Sword of the Stars | PC | 1.0.12 | Original | | P/N 21133-5 | |
| SWAT 4 (Disc 1) | PC | 1.0.31973.0 | Covermount | | | |
| SimCity 3000 | PC | 1.0.557.0 | Original | | MXX08801496D | |
| Severance: Blade of Darkness | PC | 1.00 | Original | | PSEVCDGE00 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.00 | Original | | 41118.101.UK | |
| Sensible Soccer 2006 | PC | 1.00.0000 | Original | | MSS1CDEU00 | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Original | | | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Rerelease | | 8541830R | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Original, Collector's Edition | | 8541830 | |
| Star Wars: Empire at War: Forces of Corruption (Disc 1) | PC | 1.00.55911 | Original | | 7131830 | |
| Sid Meier's Civilization III: Play the World | PC | 1.01f | Original | | Part # 24115CD | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | ORE08901524D | |
| Submarine Titans | PC | 1.1.0 | Original | | | |
| Submarine Titans | PC | 1.1.0 | Original | | | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 1) | PC | 1.10.0.111 | Original, Slim Case | | 1536707 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original, Slim Case | | 1536717 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | MXX08005156D, MXX08005156D/ANZ | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 1) | PC | 1.13.0.135 | Original, Slim Case | | 1537107 | |
| Sid Meier's Civilization III: Play the World | PC | 1.14f | Rerelease | | 1007417/2 | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | MXD08006831D, MXX08006256D | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | 1578207 | |
| SpellForce: The Order of Dawn (Disc 1) (Installa/Esegui CD) | PC | 1.52.61407 | Original | | ROSPELLFOR0027LAB1 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 2.00 | Original | | 41127.101.UK | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) สตาร์ วอร์ส: ไนท์ส ออฟ ดิ โอลด์ รีพับลิค II: เดอะ ซิทห์ ลอร์ด | PC | 2.00.424 | Original | | | |
| Spy Kids: Mega Mission Zone | PC | 3.6.27 | Original | | H3343 | |
| Söldner: Secret Wars: Reloaded | PC | 30600 | Rerelease | | ROSOELDNER0008LAB | |
| SWAT 4 (Disc 1) | PC | 31973 2005/02/23 | Gold Edition | | S2164601 | |
| SWAT 4 (Disc 2) | PC | 31973 2005/02/23 | Gold Edition | | S2164602 | |
| SWAT 4: Sindikat Stechkina SWAT 4: Синдикат Стечкина | PC | 82610 2005/11/22 | Gold Edition | | S2164603 | |
| The Sting! | PC | v2.0e | Original | | ROTHESTING0004USLAB | |