| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Sengoku Bishoujo Emaki: Kuu o Kiru!!
戦国美少女絵巻 空を斬る！！ | PC | | Original |  | TGL-98 0220 |  |
| Sengoku Bishoujo Emaki: Kuu o Kiru!! Harukaze no Shou
戦国美少女絵巻 空を斬る！！ ～春風の章～ | PC | | Original | | | |
| Sengoku Hime: Hana: Shinroku Tenka wo Kirisaku Hikari to Kage
戦極姫・華 ~真録・天下を切り裂く光と影~ | PC | | Original | | | |
| Sengoku Hime: Senran no Yo ni Homura Tatsu: Shinsouban
戦極姫 ~戦乱の世に焔立つ~【新装版】 | PC | | Unicorn-a Selection 6 | | | |
| Sengoku Shougi
戦国将棋 | PC | | Power Game 1800 Series | | GA-0001 | |
 | Senha N. 1 | PC | | |  | | |
| Senjou de Shoujo wa Karada o Kakeru: Briefing Disc
戦場デ少女ハ躰ヲカケル ブリーフィングDISC | PC | | Demo | | | |
| Senkaku Mondai o Yatchimasu 2
尖閣問題を殺っちます２ | PC | | Original | | | |
 | Sensei 2
Запретное влечение | PC | | Original |  | | |
 | Sensei 2 | PC | | Original | | GC-007 | |
 | Sensible Golf | PC | | Original | | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Sensible Soccer '98 | PC | | Original |      | | |
| Sensible Soccer: European Club Edition | PC | | Original | | | |
| Sensible World of Soccer '96/'97 (Upgrade PC CD-ROM Disc) | PC | | Original | | | |
| Sentient | PC | | Original | | | |
| Sentimental Graffiti (Disc 1)
センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01A | |
| Sentimental Graffiti (Disc 2)
センチメンタルグラフティ | PC | | Original | | ID NO.9718-X8-01B | |
| Sentinel Returns | PC | | Dice | | DMM 005448 | |
| Sentinel Returns | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | SENTENCD1 | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
 | Sentinel: Descendants in Time (Disc 2) | PC | | Original | | SENTENCD2 | |
| Sento Monogatari: Sono I
「占都物語」 そのＩ | PC | | Original | | | |
| Sentou Kokka: Improved
戦闘国家 ＩＭＰＲＯＶＥＤ | PC | | Original | | YP-1001 | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 1) (Installation CD-ROM)
戦闘妖精雪風～妖精の舞う空～ | PC | | Original | | SYYi-V1.00 | |
| Sentou Yousei Yukikaze: Yousei no Mau Sora (Disc 2) (Game CD-ROM)
戦闘妖精雪風～妖精の舞う空～ | PC | | Original | | SYYg-V1.00 | |
 | Separate Hearts
散碎的原色 | PC | | Original |  | CV022 | |
| Septerra Core: Legacy of the Creator | PC | | Original | | | |
 | Septerra Core: Legacy of the Creator | PC | | Covermount | | ADB 0103 | |
| Septerra Core: Legacy of the Creator | PC | | Original | | 1CSP OR03 0020 IR | |
| Sequence Palladium
シークエンス パラディウム | PC | | Original | | KGDP004 | |
| Sequence Palladium
シークエンス パラディウム | PC | | DigiCube, Media Kite Great Series | | DWRPM-00089, MKW-182 | |
| Sequence Palladium 2 Mania Kit | PC | | Original | | KGD-0060 | |
| Sequence Palladium 2: Yami no Shousei
シークエンス・パラディウム２ ～闇の笑声～ | PC | | Rerelease | | KGD-04080 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 1)
シークエンス・パラディウム３ ～泡沫の天地～ | PC | | Original | | KGD-04060 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 2)
シークエンス・パラディウム３ ～泡沫の天地～ | PC | | Original | | KGD-04061 | |
| Sequence Palladium Aizouban
シークエンス パラディウム 愛蔵版 | PC | | Original | | KGDP075 | |
| Sequence Palladium Mania Kit: Desktop Accessory
シークエンス・パラディウム マニアキット デスクトップアクセサリ | PC | | Original | | WIC-6346 | |
| Sequence Palladium Premium Digital Novel | PC | | PC Game Bundle | | KGD-06021 | |
| Seraphim: Saigo no Tenshi
セラフィム 最後の天使 | PC | | Original | | SCR-003 | |
 | Serial Cleaner | PC | | Polska Kolekcja Gier Indie / Edycja Premium | | | |
| Serious Sam 3: BFE | PC | | Original | | MTC000692-D | |
| Serious Sam HD: The First Encounter | PC | | Original | | | |
| Serious Sam HD: The First Encounter
Крутой Сэм HD: Первая кровь | PC | | Original | | | |
| Serious Sam HD: The Second Encounter
Serious Sam HD: Второе Пришествие | PC | | Original | | | |
| Serious Sam II | PC | | Sold Out Software | | | |
 | Serious Sam II | PC | | Original | | | |
| Serious Sam II | PC | | Demo | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | | Original, Rerelease | | | |
| Serious Sam: Złota Edycja (Disc 1) | PC | | Kolekcja Klasyki |  | CENEGA 395a/PCCD-ROM/2006 | |
| Serious Sam: Złota Edycja (Disc 2) | PC | | Kolekcja Klasyki | | CENEGA 395b/PCCD-ROM/2006 | |
| Serp i Molot
Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 1)
Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 2)
Серп и Молот | PC | | 1C: Igroteka | | | |
| Serp i Molot (Disc 3)
Серп и Молот | PC | | 1C: Igroteka | | | |
| The Serpent of Isis: The First 2 Chapters
The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Serve & Volley | PC | | Telstar Fun & Games | | TFGD 2178/4 | |
| Sesame Street Search & Learn Adventures | PC | | software for the fun of it! | | | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the Fun of It! | | EOA844AE-CD, KES005 | |
| Sesame Street Toddler | PC | | Adventure Workshop Tots | | 32180-CD1 v1.0 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's Art Workshop | PC | | Software for the Fun of It! | | KES186 | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
 | Sesame Street: Elmo's World | PC | | Original | | 2231A | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: Let's Make a Word! | PC | | Original | | 7418 | |
| Sesame Street: Let's Make a Word! | PC | | Software for the Fun of It! | | HT99200 | |
| Sesame Street: Let's Make a Word! | PC | | Software for the Fun of It! | | KES006 | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Let's Make a Word! | PC | | Original | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Music Maker | PC | | Original | | | |
| Sesame Street: Numbers
Улица Сезам: Учись считать | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: Preschool
Улица Сезам: Элмо готовит в школу | PC | | Original | | | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: The Adventures of Elmo in Grouchland | PC | | Original | | 24138-0919 | |
| Sesamstrasse: Auf die Krümel, fertig, los! | PC | | Rerelease | | GSL854AG-CD | |
| Sethi und das Geheimnis der Neandertaler | PC | | Rerelease | | | |
| Sethi: Abenteuer im Mittelalter
National Geographic: Sethi: Abenteuer im Mittelalter | PC | | Original | | | |
| The Settlers 7: Paths to a Kingdom | PC | | Original, Ubisoft Exclusive Think | | 300028951, 300028952, BLG604/D | |
| The Settlers II | PC | | Demo | | | |
| The Settlers II: 10-lecie
The Settlers II: 10th Anniversary | PC | | Original | | | |
