Region | Title | System | Version | Edition | Languages | Serial | Status |
| SBK 09: Superbike World Championship | PC | 1.0 | Just For Gamers | | JFG10-SSWC-OBL | |
| SBK X: Superbike World Championship | PC | 1.0 | Original | | | |
| Scacchi 3D | PC | | Microforum | | | |
| Scania Truck Driving Simulator: The Game | PC | 1.0.0 | Green Pepper | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Big Bytes | | 50004PCG | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| SCAR: Squadra Corse Alfa Romeo SCAR: Спортивная команда Альфа Ромео | PC | | Original | | | |
| Scarab S.C.A.R.A.B. | PC | | Original | | EAE08801181D | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | S1004042 | |
| Scarface: The World Is Yours | PC | 1.00.1 | Rerelease | | S1004045 | |
| Scarface: The World Is Yours | PC | 1.00.1 | BestSeller Series | | S1004050 | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | S1004053 | |
| Scarface: The World Is Yours Scarface: Człowiek z blizną | PC | 1.00.1 | eXtra Klasyka XK HIT | | S1180601 | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Scarlett Scarlett ~スカーレット~ | PC | 1.00 | Shokai Genteiban | | TPB-0060 | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 1) | PC | | Press Kit | | | |
| SCEE Media Assets: Games Convention / Leipzig: August 20th 2008 (Disc 2) | PC | | Press Kit | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| Scenariomania Scenariomania Vol. 1 | PC | | Original | | | |
| Scene It? Twilight | PC | 1.29.1.1 | Original | | SIT-DVD-EUR | |
| Schach & Matt | PC | | Original | | | |
| Schach & Matt 2 | PC | | Original | | | |
| Der Schatz der Versunkenen Brigantine | PC | | Original | | | |
| Der Schatz von El Dorado | PC | | Original | | | |
| Schiene & Strasse: Der 3D-Transport-Manager: 1820-2020 | PC | | Original | | | |
| Schiff-Simulator 2005 Virtual Sailor 6.8 | PC | | Original | | 31059 | |
| Schiff-Simulator 2008 Ship Simulator 2008 | PC | | Original | | | |
| Schiff-Simulator 2008 | PC | | Original | | Artikelnummer 31114 | |
| Schizm II: Kameleon (Disc 2) | PC | | Original | | | |
| Schizm II: Kameleon (Disc 3) | PC | | Original | | | |
| Schizm: Mysterious Journey (Seite A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Seite B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | | Original | | | |
| Schizm: Mysterious Journey (Side A) スキズム ~謎めく旅路~ | PC | Build: 744 | DVD-ROM Edition | | TSYC-W1012E1-1 | |
| Schizm: Mysterious Journey (Side B) スキズム ~謎めく旅路~ | PC | Build: 744 | DVD-ROM Edition | | TSYC-W1012E1-2 | |
| Schizm: Mysterious Journey (Side A) | PC | | Rerelease | | | |
| Schizm: Mysterious Journey (Side B) | PC | | Rerelease | | | |
| Schizm: Mysterious Journey (Side A) | PC | Build 744 | Original | | | |
| Schizm: Mysterious Journey (Side B) | PC | Build 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | Build: 744 | Original | | | |
| Schizm: Mysterious Journey (Side A) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey (Side B) | PC | | DVD-ROM Edition | | | |
| Schizm: Mysterious Journey | PC | 0.99 | Playable Demo | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | SZM844AB-CD1 | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | SZM844AB-CD2 | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | SZM844AB-CD3 | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | SZM844AB-CD4 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | SZM844AB-CD5 | |
| Schizm: Prawdziwe Wyzwanie (Strona B) | PC | | Original | | AMDVD001 | |
| Schizm: Prawdziwe Wyzwanie (Strona A) | PC | Build: 744 | Original | | AMDVD001 | |
| Die Schlaue Bande: 5. Klasse Lernsystem | PC | | Original | | | |
| Die Schlaue Bande: 6. Klasse Lernsystem | PC | | Original | | | |
| Schleichfahrt | PC | | Original, Classics | | | |
| Schleichfahrt | PC | | Hemming | | | |
| Schleichfahrt | PC | | Original | | | |
| Schleichfahrt | PC | | | | | |
| Die Schlümpfe: Farben und Formen | PC | | Original | | | |
| Schmidt Interaktivspaß: Brettspiele | PC | | Original | | S0022616 | |
| Schmidt Interaktivspass: Doppelkopf | PC | 1.0.0.0 | Original | | S0022421 | |
| Schmidt Interaktivspass: Kartenspiele | PC | 1.0.0.0 | Original | | S0022612 | |
| Schmidt Interaktivspaß: Mahjong | PC | | Original | | S0023095 | |
| Schmidt Interaktivspaß: Skat | PC | | Original | | S0022595 | |
| Schmidt Interaktivspaß: Solitaire | PC | 1.0.0.0 | Original | | S0023093 | |
| Schmidt Interaktivspaß: Spiele für Kids | PC | | Original | | S0022620 | |
| Scholastic's The Magic School Bus Discovers Flight: Activity Center | PC | 1.0.0.2 | Original | | 0201 Part No. X06-16068 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Scholastic's The Magic School Bus Explores in the Age of Dinosaurs | PC | 1.0.0.0 | Scholastic | | 0796 Part No. 91354 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | 1.0.0.1528 | Handi-Snacks Promotional | | 0396 Part No. X03-27325, Disc Assy. 452-052-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Rainforest | PC | 1.0 | Original | | 1001 Part No. X08-50154, CD SET 420-056-001 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus Explores the World of Animals | PC | | Original, The Magic School Bus: Bonus Pack | | 0299 Part No. X03-94114, 1001 Part No. X08-51052 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus: Jungle no Fushigi マジック スクール バス ジャングルのふしぎ | PC | | Original | | PRIR-01005 | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| School Days スクールデイズ | PC | 1.1.1.0 | Renewal Package | | | |
| School Rumble: Neru Musume wa Sodatsu.: DTA Daisuki Tenma Accessory スクールランブル ねる娘は育つ。 DTA<大好き 天満アクセサリー> | PC | | DX Pack | | MII-012 | |
| School Tycoon | PC | | Scholastic | | P/N: CDR 21661-1R | |
| School Tycoon | PC | | Original | | | |
| School Tycoon | PC | v1 | Original | | | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Phonics: Grades 2-3 | PC | v.5 | Original | | 08064 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! Grammar Rock | PC | | SmartSaver | | SGR744AE-CD | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | PC | 1.0 | Scholastic | | P/N CDR9835984 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Math Rock | PC | | Smart Saver | | SHR744AE-CD | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolmates: The Mystery of the Magical Bracelet | PC | | Original | | | |
| Schrei-Ten SCHREI・TEN シュライテン | PC | | Shokai Genteiban | | PISCKISS-01 | |
| Schrottplatz-Simulator 2011 | PC | | Original | | | |
| Les Schtroumpfs: Le Téléportaschtroumpf | PC | | Original | | SCHTRFR5011 | |
| Der Schuh des Manitu Der Schuh des Manitu: Das Computerspiel zum Film | PC | | Original | | | |
| Das Schwarze Auge: Blackguards | PC | | Original | | 502153 | |
| Das Schwarze Auge: Die Schicksalsklinge | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Die Schicksalsklinge | PC | 3.02 | Gold Games (CD 2) | | SPI 035 | |
| Das Schwarze Auge: Die Schicksalsklinge | PC | 3.02 | TopWare | | SPI 030 | |
| Das Schwarze Auge: Drakensang | PC | | Original, Limited Collector's Edition | | | |
| Das Schwarze Auge: Drakensang | PC | 1.11 | Software Pyramide | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Phileassons Geheimnis | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Platinum Edition | PC | | Original | | | |
| Das Schwarze Auge: Satinavs Ketten | PC | | Limitierte Erstauflage | | ECD008798M ECD008799M ECD008907K ECD900830D 23032012-00 | |
| Das Schwarze Auge: Schatten über Riva | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Schatten über Riva | PC | | Gold Games 2 (CD 4) | | | |
| Das Schwarze Auge: Schatten über Riva | PC | | Gold Games 2 (CD 4) | | SPI 046 | |
| Das Schwarze Auge: Schatten über Riva | PC | | All You Can Play: Adventure & Fantasy | | | |
| Das Schwarze Auge: Schatten über Riva | PC | 1.00 | Original | | SPI 032 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | Gold Games (CD 3) | | SPI 035 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | TopWare | | SPI 031 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Das Schwarze Auge: Die Nordlandtrilogie | | SPI042 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | | Original | | | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | Gold Games (CD 4) | | SPI 035 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | TopWare | | SPI 031 | |
| Schwarzschild GXR: Toki no Tsukaibito シュヴァルツシルトGXR 時現の遣人 | PC | | Original | | ID NO.9674-68-01 | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| SCI Media Kit: Version: 2 | PC | | Press Kit | | | |
| SCI Media Kit: Version: 4 SCI Media Kit: Version: 4.0 | PC | | Press Kit | | | |
| The Sci-Fi Collection | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Scissors 'n' Stones | PC | | Original | | | |
| Scooby Doo: Strachy na Lachy | PC | | | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Scooby-Doo 2: Monsters Unleashed | PC | | PC Fun Club | | PFC028/D | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | | GSP | | 1063A | |
| Scooby-Doo! First Frights + Scooby-Doo! The Mystery Begins (Asset Disc) | PC | | Press Kit | | | |
| Scooby-Doo! Jinx at the Sphinx | PC | | GSP | | 1065A | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.0 | | | SCA844AB | |
| Scooby-Doo! Jinx at the Sphinx | PC | | Scholastic | | 380849-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Scooby-Doo! Le Mystere du Parc Fantome | PC | | Original | | | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Phantom of the Knight | PC | | SoftKey | | SPK854BB-CD | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooby-Doo! Phantom of the Knight | PC | | GSP | | 1064A | |
| Scooby-Doo! Pierwsze Strachy | PC | | Demo | | | |
| Scooby-Doo! Piramidalna Zagadka | PC | 1.0 | Original | | SCA844AB-CD | |
| Scooby-Doo! Priklyucheniya v gorode prizrakov Скуби-Ду! Приключения в городе призраков | PC | | 1C: Igroteka | | | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0 | Original | | SGW844AB-CD | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0.1.8 | SoftKey | | SGW854BB, SGW854BB-CD | |
| Scooby-Doo! Showdown in Ghost Town | PC | | GSP | | 1066A | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooter Pro | PC | | Original | | APWCDR1001 | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooter's Magic Castle & Kid Pix | PC | | Bundle Version Creative Labs OEM | | | |
| SCOP | PC | | Original | | SPR-1405 | |
| Scorched 3D | PC | | Original | | | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorcher | PC | | Original | | | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Score 4 | PC | | Original | | | |
| Score International Baja 1000: The Official Game | PC | | Original | | 35619./101.US | |
| Scotland Yard | PC | | Original | | | |
| Scotland Yard | PC | | Original | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| The Scottish Open: Virtual Golf | PC | | Euro Power Pack | | | |
| Scrabble | PC | | General Mills | | | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble CD-ROM | PC | | Original | | 23713-0726 Rev a | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble Interactive: 2003 Edition | PC | | Original | | | |
| Scrabble Interactive: 2003 Edition | PC | | Focus Essential | | ESS493 | |
| Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scrabble Interactive: 2007 Edition | PC | 1.1.0 | Ubisoft eXclusive / Focus Essential | | ESS760 | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scratches | PC | | Original | | | |
| Scratches | PC | | Original | | | |
| Scratches: Dans l'Antre de la Peur | PC | 0.92 Build 109 | Original | | 7816 | |
| Scratches: Director's Cut (Disc 1) | PC | | Original | | | |
| Scratches: Director's Cut (Disc 2) | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Scratches: Graffi Mortali | PC | | Original | | | |
| Screamball: The Ultimate Pinball Experience | PC | | Original | | | |
| Screamer | PC | | Award Winners No. 1 | | EI-1041 | |
| Screamer | PC | | Sold Out Software | | | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | Original, White Label | | | |
| Screamer | PC | | Screamer Injection | | | |
| Screamer | PC | | Sold Out Extreme | | | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | White Label | | | |
| Screamer | PC | | White Label | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer 2 | PC | | Sold Out Software | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer 2 | PC | | Original | | | |
| Screamer 2 | PC | | eXtra Klasyka | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screamer 4x4 | PC | | Sold Out Software | | | |
| Screamer 4x4 | PC | | Original | | CD-W95-V008-M24 | |
| Screamer 4x4 | PC | 1.0 | Original | | CHA-004 | |
| Screamer 4x4 | PC | | Covermount | | | |
| Screamer Rally | PC | | Sold Out Software | | | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
| Screamer Rally | PC | sov 2.1 | Sold Out Software | | sov. 2.1 | |
| Screamer Rally | PC | | Covermount | | G02 | |
| Screaming Skies | PC | | Tewi | | Bestell-Nr. 27669 | |
| Screen Club: Pocket Monsters スクリーンクラブ ポケットモンスター | PC | | Original | | | |
| Screen Fighter Screen Saver スクリーンファイター スクリーンセーバー | PC | | Original | | SRC-00001 | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited (Asset Disc) | PC | | Press Kit | | | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| The Scroll | PC | | | | | |
| The Scroll Daughter of Serpents | PC | | Original | | | |
| Scubeginners: I Misteri di Dive Island | PC | 1.1 | Original | | | |
| Scudetto 2 | PC | 1.48 | CD-ROM Classic Collection 3 | | | |
| Scudetto 4: Championship Manager: Stagione 2002-2003 | PC | 4.0.4 | Original | | MCHM4PIT81 | |
| SD Gundam: GGeneration SD 건담: G-제네레이션 | PC | 1.0.0.1 | Original | | | |
| SD Gundam: GGeneration DA SDガンダム GジェネレーションDA | PC | 1.00 | DigiCube PC Series | | DWRMS-00158 | |
| SD Gundam: GGeneration DA SDガンダム GジェネレーションDA | PC | 1.1.0.29 | Original | | BSE-2002 | |
| SD Qlympics Olympic Challenge | PC | | Grabit | | GDL031 | |
| SDevTC: Version 2 | PC | 2 | Original | | | |
| SDevTC: Version 2.4 | PC | 2.4 | Original | | DTL-S2200 | |
| SDS Star Divers スターダイバーズ | PC | | Original | | CS001 | |
| Sea Adventures | PC | | Microforum | | | |
| Sea Battle | PC | | Original | | | |
| Sea Dogs | PC | 1.06 | Green Pepper | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Sold Out Software | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Dogs: Piraci | PC | 1.06 | Nowa eXtra Klasyka | | | |
| Sea Dogs: Piraci | PC | 1.06 | Original | | | |
| Sea Plane Adventures Sea Plane Adventures for FS2002/2004 | PC | | Original | | | |
| Sea Rescue | PC | | Nestlé Corn Flakes | | | |
| Sea War Sea War: Entscheidungsschlacht im Pazifik | PC | | Original | | SPI 023 | |
| Seafight II | PC | | Original | | | |
| Seal of Evil | PC | | Original | | 904066DVD | |
| Seal: Travelers of Destiny SEAL~運命の旅人~ | PC | | Original | | MKD-1390 | |
| SeaMail: Baby Gillman-hen: Ningen Kankei Shuufuku Hozen Pet シーメール 〈ベビーギルマン編〉 人間関係修復保全ペット | PC | 1.0 | Original | | VPC-0100 | |
| Search & Rescue 3 | PC | 1.0.0.0 | Original | | | |
| Search & Rescue 3 | PC | | Original | | ASS256A181-0001-0001-02 | |
| Search and Rescue Air Rescue | PC | | Grabit | | GDL024 | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| The Second Guest | PC | | Original | | | |
| Second Sight | PC | | Bundle Version ASUS OEM | | V468 | |
| Second Sight | PC | | Original | | | |
| Second Sight | PC | | 1C: Kollekciya igrushek | | | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Agent Clank (Media Information) | PC | | Press Kit | | | |
| Secret Files 2: Puritas Cordis | PC | | Original | | ECD900341D | |
| Secret Files: Il Mistero di Tunguska | PC | 1.00 | Covermount | | | |
| Secret Files: Tunguska | PC | 1.03 | Original, Xplosiv | | ECD008099M 00060722-01, XP-2221 3026412 | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Game: Code:Revise: Trial Version シークレットゲーム CODE:Revise 体験版 | PC | | Demo | | | |
| The Secret Island of Dr. Quandary | PC | | Softkey | | PDQ944AB-CD | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| The Secret of Googol 1: Reshaping Googol: Submarine / Tower | PC | 2.0 | Original | | | |
| The Secret of Googol 2: Reshaping Googol: Castle / Ocean | PC | 2.0 | Original | | | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PC | 2.0 | Original | | | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PC | 2.0 | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island | PC | | Collezione CD-Rom by C.T.O. | | | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island | PC | 2.3 | Original, Bundle Version OEM | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | | White Label: Doubles | | | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge The Monkey Island Bounty Pack: The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | 1.0 | LucasArts Classics: The Monkey Island Bounty Pack | | 3000012.101.UK | |
| The Secret of Monkey Island: Special Edition (International Trailer) | PC | | Press Kit | | | |
| The Secret of the Nautilus | PC | | Original | | JVEENCD1 | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| Secret Safari シークレットサファリ | PC | | Original | | VIRL-8 | |
| Secret Service | PC | 1.0 | Original | | 35635.101.UK, 35635.101.US | |
| Secret Service CD 36 | PC | | | | | |
| Secret Service CD 37 | PC | | | | | |
| Secret Service CD 38 | PC | | | | | |
| Secret Service CD 39 | PC | | | | | |
| Secret Service CD 40 | PC | | | | | |
| Secret Service CD 41 | PC | | | | | |
| Secret Service CD 43 | PC | | | | | |
| Secret Service CD 44 (Strona A) | PC | | | | | |
| Secret Service CD 44 (Strona B) | PC | | | | | |
| Secret Service CD 45 | PC | | | | | |
| Secret Service CD 46 | PC | | | | | |
| Secret Service CD 47 (Strona A) | PC | | | | | |
| Secret Service CD 47 (Strona B) | PC | | | | | |
| Secret Service CD 48 (Strona A) | PC | | | | | |
| Secret Service CD 48 (Strona B) | PC | | | | | |
| Secret Service CD 49 (Strona A) | PC | | | | | |
| Secret Service CD 49 (Strona B) | PC | | | | | |
| Secret Service CD 50 (Strona A) | PC | | | | | |
| Secret Service CD 50 (Strona B) | PC | | | | | |
| Secret Service CD 51 (Strona B) | PC | | | | | |
| Secret Service CD 51 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona A) | PC | | | | | |
| Secret Service CD 52 (Strona B) | PC | | | | | |
| Secret Service CD 53 (Strona A) | PC | | | | | |
| Secret Service CD 53 (Strona B) | PC | | | | | |
| Secret Service CD 54 (Strona A) | PC | | | | | |
| Secret Service CD 54 (Strona B) | PC | | | | | |
| Secret Service CD 55 (Strona A) | PC | | | | | |
| Secret Service CD 55 (Strona B) | PC | | | | | |
| Secret Service CD 56 (Strona A) | PC | | | | | |
| Secret Service CD 56 (Strona B) | PC | | | | | |
| Secret Service CD 57 (Strona A) | PC | | | | | |
| Secret Service CD 57 (Strona B) | PC | | | | | |
| Secret Service CD 58 (Strona A) | PC | | | | | |
| Secret Service CD 58 (Strona B) | PC | | | | | |
| Secret Service CD 59 (Strona A) | PC | | | | | |
| Secret Service CD 59 (Strona B) | PC | | | | | |
| Secret Service CD 60 | PC | | | | | |
| Secret Service CD 61 | PC | | | | | |
| Secret Service CD 64 | PC | | | | | |
| Secret Service CD 87 | PC | | | | | |
| Secret Service CD 88 | PC | | | | | |
| Secret Service CD 89 | PC | | | | | |
| Secret Service CD 90 | PC | | | | | |
| Secret Service CD 91 | PC | | | | | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Service: Wydanie Specjalne Alone in the Dark | PC | | | | | |
| Secret Weapons of the Luftwaffe | PC | | Collezione CD-Rom by C.T.O. | | | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 32609.101.UK | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 32609.102.UK | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 32609.103.UK | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 32609.104.UK | |
| Secret Weapons over Normandy (Disc 1) | PC | | Original | | 32609.101.GM | |
| Secret Weapons over Normandy (Disc 2) | PC | | Original | | 32609.102.GM | |
| Secret Weapons over Normandy (Disc 3) | PC | | Original | | 32609.103.GM | |
| Secret Weapons over Normandy (Disc 4) (Spiel-CD) | PC | | Original | | 32609.104.GM | |
| Secret Weapons over Normandy (Disco 1) | PC | 1.0 | Original | | 32609.101.IT | |
| Secret Weapons over Normandy (Disco 2) | PC | 1.0 | Original | | 32609.102.IT | |
| Secret Weapons over Normandy (Disco 3) | PC | 1.0 | Original | | 32609.103.IT | |
| Secret Weapons over Normandy (Disco 4) (Disco di Gioco) | PC | 1.0 | Original | | 32609.104.IT | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secret World (Disc 1) | PC | | Original | | EAX07709446D | |
| The Secret World (Disc 2) | PC | | Original | | EAX07709446D2 | |
| Les Secrets d'Alamut (Disc 1) | PC | | Original | | ALAFR1P | |
| Les Secrets d'Alamut (Disc 2) | PC | | Original | | ALAFR2P | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| The Secrets of Da Vinci: Il Manoscritto Proibito (Disc 1) | PC | 1.02 | Original | | | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 2) | PC | 1.02 | Original | | | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 1) Sekrety Leonarda Da Vinci: Zakazany Manuskrypt | PC | | | | | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Dark: Der finstere Berg | PC | | Original | | | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | 1.0 | Original | | 74311-LBL | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| SeeIn Ao SeeIn青 | PC | 1.00 | Original | | ALS-0040 | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy | PC | | Original | | CDR3015 | |
| Seek and Destroy Seek & Destroy | PC | | Original | | EPSAD01 | |
| Seek and Destroy Seek & Destroy | PC | 1.0 | Original | | J230D | |
| Sega Bass Fishing 钓鱼高手 | PC | 1.0 | Original | | | |
| Sega Bass Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1607 | |
| Sega Bass Fishing | PC | | Original | | EI-1269 | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega E3 2002 Art Disc | PC | | Press Kit | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Game Honpo: Puyo Puyo セガゲーム本舗 ぷよぷよ | PC | | Original | | | |
| Sega Game Honpo: Wonder Boy V, Monster World III セガゲーム本舗 ワンダーボーイⅤ モンスターワールドⅢ | PC | | Original | | SGH-013 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original, Xplosiv | | EI-1266-1, EI-1266-1 ENGLISH | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original | | EI-1266-1 | |
| Sega GT (Disc 2) (Play Disc) | PC | | Original | | EI-1266-2 | |
| Sega Hard Historia セガハードヒストリーア | PC | | Book Bundle | | | |
| Sega Marine Fishing | PC | | Sega Bass Fishing & Sega Marine Fishing: Xplosiv | | EI-1606 | |
| Sega Mega Drive Classic Collection Volume 1 | PC | | Original | | SEGA-PC118 | |
| Sega Mega Drive Classic Collection Volume 2 | PC | | Original | | SEGA-PC119 | |
| Sega Mega Drive Classic Collection Volume 3 | PC | | Original | | SEGA-PC120 | |
| Sega Mega Drive Classic Collection Volume 4 | PC | | Original | | SEGA-PC121 | |
| Sega Mega Drive Classic Collection: Złota Edycja | PC | 1.0.019 | Platynowa Kolekcja | | P_37010_04A_PL | |
| Sega Memorial Selection: Dear 80's Videogame Best 3 | PC | | Ultra 2000/Ultra Series | | MKW-183 | |
| Sega PC Collection Vol. 1 | PC | | PC Game Bundle | | 673-04569 | |
| Sega PC Collection Vol. 2 | PC | | PC Game Bundle | | 673-04572 | |
| Sega PC Greatest Hits Series Vol. 2 | PC | | Taikenban, PC Game Bundle | | 670-10528 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | PC Game Bundle | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11877 | |
| Sega PC Special Trydisc Vol. 1 Sega PC すべしゃる トライディスク Vol.1 | PC | | PC Game Bundle | | 670-9986 | |
| Sega Press Materials | PC | | Press Kit | | | |
| Sega Puzzle Pack | PC | | Original | | 673-01815 | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally | PC | 1.0 | Original | | SEGA-PC056 | |
| Sega Rally (Uaktualnienie Wersji Polskiej) | PC | | Original, TopSeller | | | |
| Sega Rally | PC | 3.2.0.3 | Original, TopSeller | | | |
| Sega Rally 2 (Install Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Play Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Disc 1) (Install Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-1 | |
| Sega Rally 2 (Disc 2) (Play Disc) Sega Rally 2: Sega Rally Championship | PC | | Original, Xplosiv | | EI-1183-2 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally 2: Sega Rally Championship (Install Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally 2: Sega Rally Championship (Play Disc) セガラリー2 | PC | | DigiCube PC | | DWRPD-00081 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Rally Championship PC | PC | 1.0 | Original | | MK 85048-50 | |
| Sega Rally Championship PC | PC | 1.0 | Expert Software | | XP 202022 01 | |
| Sega Rally Championship PC | PC | 2.11 | Original | | MK 85048MX-50 | |
| Sega Rally Championship PC | PC | 2.11 | Fair Game, Grabit | | FG-1282, GDL016 | |
| Sega Rally Championship PC | PC | | Green Pepper | | | |