Region | Title | System | Version | Edition | Languages | Serial | Status |
| Singularity | PC | | Press Kit | | | |
| Star Trek: Starfleet Command | PC | 1.01.00 | Rerelease | | CD-C95-637-2 | |
| Star Trek: Starfleet Command (Bonus CD) | PC | | Original | | CD-C95-637-1 | |
| Star Wars: Episode I: The Phantom Menace: Naboo Missions | PC | 1.0 | Bundle Version OEM | | 3151830, CD-W581950-MLE | |
| Star Wars: X-Wing Alliance: Imperial Entanglements | PC | 1.0 | Bundle Version OEM | | 2091831, CD-C951918-VOE | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Electronic Press Kit) | PC | | Press Kit | | | |
| Sonic 3D Blast | PC | 1.0 | Twin Pack | | 6822 01 | |
| Sonic & Knuckles Collection | PC | | Expert Software | | 6820 01 | |
| Sports Illustrated Kids: Basketball | PC | | Wendy's Kids' Meal | | | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sierra Press Kit | PC | | Press Kit | | | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sam & Max Hit the Road | PC | | The LucasArts Archives Vol. I | | | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| Star Wars: Rebel Assault: Special Edition | PC | | The LucasArts Archives Vol. I | | 636130 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | 798707 | |
| Star Control 3 | PC | | Original | | Part #:5000-00419 | |
| Spellcasting: Party Pak | PC | 1.0 | Original | | | |
| Super Solvers: Midnight Rescue! | PC | 1.1 | Rerelease | | CSM744AE-CD | |
| Super Solvers: OutNumbered! | PC | 1.1 | Rerelease | | CSO744AE-CD | |
| Shrek 2 (Final Press Kit) | PC | | Press Kit | | | |
| Shadow Company: Left for Dead (Digital Press Kit) | PC | | Press Kit | | 5051895 | |
| Shannara | PC | 1.0 | Original | | | |
| Star Wars: Episode I: Cover Disk 4 | PC | | Press Kit | | | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-A | |
| Street Fighter II | PC | | Original | | 9108 | |
| Street Fighter Alpha: Warriors' Dreams | PC | | Original | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| SNK Playmore E3 2006 Games | PC | | Press Kit | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| School Tycoon | PC | v1 | Original | | | |
| Snap! 400 Word Searches | PC | | Original | | CS-296 | |
| The Ship | PC | | Original | | | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| Star Trek: Starship Creator Deluxe | PC | | Original | | 0-671-31776-8 | |
| Super Street Fighter II Turbo HD Remix (Asset Disc) | PC | | Super Turbo Hyper Champion Special Edition Pack | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Strong Bad's Cool Game for Attractive People | PC | 1.5.0.0 | Original | | | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | | | | 1462607 | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | PC | | | | 1462617 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Star Trek: Armada | PC | 1.1 | Original | | 1000913.101.US | |
| Star Wars: Fall Force Gaming Preview | PC | 1.0 | Original | | 8330330 | |
| Sniper Elite | PC | | Original | | 40009 | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Sniper: Path of Vengeance | PC | | Original | | | |
| Soldiers of Anarchy | PC | | Original | | S5280010 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Rerelease, The LucasArts Archives Vol. III | | 8041834 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Demo: Special Limited Edition | | 647230 | |
| Star Wars: Rogue Squadron 3D | PC | 1.3 | Rerelease, CompUSA Exclusive | | 6521830R2 | |
| Stronghold 2 (Disc 1) (Install) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| Stronghold 2 (Disc 2) (Play) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| Snow Storm | PC | | Original | | 9099 | |
| Spec Ops: Ranger Assault | PC | | Covermount | | CDE30_CDA | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| SAS: Secure Tomorrow | PC | 1.0 | Original | | | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Sacred 2: Fallen Angel (Disc 1) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 2) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 3) | PC | | Beta | | | |
| Sacred 2: Fallen Angel (Disc 4) | PC | | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| StarCraft | PC | | BestSeller Series | | 334854216691 /1 | |
| StarCraft: Brood War (Expansion Set) | PC | | BestSeller Series | | 334854216691 /2 | |
| StarCraft (PDF Manual) | PC | | BestSeller Series | | 334854216691 /3 | |
| Super Collapse! 3 | PC | | Original | | | |
| South Park: The Fractured But Whole (Disc 1) | PC | | Gold Edition | | UBP60802045-DISC1 | |
| South Park: The Fractured But Whole (Disc 2) | PC | | Gold Edition | | UBP60802045-DISC2 | |
| South Park: The Fractured But Whole (Disc 3) | PC | | Gold Edition | | UBP60802045-DISC3 | |
| Space Engineers | PC | | Limited Edition | | | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| Scratches | PC | | Original | | | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | | | 1526317 | |
| Star Wars: X-Wing vs. TIE Fighter (Multiplayer Disc) | PC | 1.00 | Original | | 2081831 | |
| Slingo Deluxe | PC | | Original | | | |
| Sudoku Crunch for Kids! | PC | | Original | | P/N 61081-CD | |
| SimAnt SimAnt: The Electronic Ant Colony | PC | | CD-ROM Classics, 10 Sims for $20 | | 1111407 | |
| Super Solvers Mission: T.H.I.N.K. | PC | 1.01 | Original | | MEM744CE-CD | |
| Sid Meier's Civilization VI | PC | | Original | | 41829-1 | |
| Sinbad: Legend of the Seven Seas | PC | 1.0 | Original | | Part # 24755CD | |
| SimCity (Preview Disc) | PC | | Target | | 7298103301 | |
| Score 4 | PC | | Original | | | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | | Original | | 1640617 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| The Sims Carnival: BumperBlast | PC | 1.0.10 | Original | | 1586907 | |
| Sorting Adventures: Interactive Activities | PC | | Original | | AAP899, PP463 | |
| The Software Toolworks CD Deluxe Pack 4 | PC | | Bundle Version OEM | | 2192610-590001/1034100, CDRM1170920 | |
| Score International Baja 1000: The Official Game | PC | | Original | | 35619./101.US | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| SimClassics: 3 in 1 Pack | PC | | Original | | 0543-000-0601-A | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| Stories: The Path of Destinies (Installation Disc) | PC | 0.0.18092 | Collector's Edition, GameTrust Collection | | | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | MXB08803894CD1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | MXB08803894CD2 | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| StarCraft II: Heart of the Swarm | PC | | Original | | | |
| StarCraft II: Wings of Liberty | PC | | Original | | | |
| The Sims 4 (Disc 1) | PC | 1.0 | Limited Edition | | 7303703301, 7303703303 | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Stonekeep | PC | 1.2 | Rerelease | | CD-ICD-045-1 | |
| SimCity Enhanced CD-ROM | PC | | Original | | CD-ICD-041-0 | |
| StarCraft II: Legacy of the Void (Disc 1) | PC | | Original | | | |
| StarCraft II: Legacy of the Void (Disc 2) | PC | | Original | | | |
| Spider-Man (Disc 2) | PC | 1.0 | Original | | 32249.102.US | |
| Spider-Man (Disc 1) | PC | 1.0 | Original | | 32249.101.US | |
| Spider-Man 3 | PC | | Original | | 33121.101.US | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | | | 7101830 | |
| SpellForce: Universe (Disc 1) | PC | 1.52 | Original | | DVD564CD | |
| SpellForce: Universe (Disc 2) | PC | 2.00 | Original | | DVD563CD | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sonic Riders (Disc 1) | PC | 1.0 | Original | | | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Spider-Man: Friend or Foe | PC | | Original | | 33167.101.US | |
| Spider-Man: Shattered Dimensions | PC | | Original | | 33355101US | |
| Spider-Man: Web of Shadows | PC | 1.0 | Original | | 33211.101.EF, 33211.101.US | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| The Silver Case | PC | 1.01 | Limited Run Games Limited Edition | | | |
| Starship Tycoon | PC | Build 2.24 | Original | | | |
| Spore | PC | 1.0 | Galactic Edition | | 1908007 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Mysteries of the Sith: Companion Missions | PC | 1.0 | Star Wars: Jedi Knight: Dark Forces II | | 7101830 | |
| Sengoku Rance 戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| Sacred Gold (Disc 1) | PC | 2.24 | Original | | 10130-CD1 | |
| Sacred Gold (Disc 2) | PC | 1.0 | Original | | 10130-CD2 | |
| Sacred Gold (Disc 3) | PC | 1.0 | Original | | 10130-CD3 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
| SpellForce: The Order of Dawn (Disc 2) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD2 v1.0 E, 28017-SM2 v1.0 F | |
| Star Wars: X-Wing vs. TIE Fighter: Flight School | PC | 1.00 | Original | | 2085830 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 2.00.424 | Original | | 3261830R1 v2.1.0.0 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | | Rerelease | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | | Rerelease | | 9521831 | |
| Software JukeBox: Home & Entertainment Edition: Vol. 1 No. 1 | PC | | Original | | CDRM1006830 | |
| Superhero League of Hoboken | PC | 1.1 | Original | | | |
| Simon the Sorcerer | PC | 1.00 | Original | | | |
| Sudoku Master | PC | | Rerelease | | 03659 | |
| Shadowrun Chronicles: Boston Lockdown | PC | 12.0.10093 | Cosmi | | DVDC6251 | |
| Star Wars Trilogy CD-ROM: Limited Edition Entertainment Utility | PC | | Original | | | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.01a | Rerelease | | 1-124-40-101 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| Storybook Weaver Deluxe | PC | 2.1 | Rerelease | | SBW744EE-CD | |
| Sinistar: Unleashed | PC | | Original | | | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.0 | Original | | PCO519CD | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Rerelease | | | |
| Soulbringer (Disc 1) | PC | | Original | | CD-C95-1077-0 | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | 1536607 | |
| The Sims 2: Happy Holiday Stuff | PC | | Original | | 1527707 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | 1578007 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| Sid Meier's Civilization II | PC | 2.42a | Risk: Gold Edition | | Product # 99227 | |
| Schizm: Mysterious Journey (Playable Demo) | PC | 0.99 | Demo | | | |
| SimTown | PC | | The Kids Collection | | 1258607 | |
| Super Collapse! II | PC | 1.33 | Original | | | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | 1457637 | |
| ShadowCaster | PC | | CD-ROM Classics | | 5393 | |
| Steel Panthers | PC | 1.0 | Original | | | |
| Steel Panthers II: Modern Battles | PC | 1.0 | Original | | 2209310-590002 | |
| Su-27 Flanker | PC | 1.1 | Rerelease | | | |
| Su-27 Flanker Mission Disk | PC | | Original | | 2212510-590001 | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| SimCity 3000 | PC | | Linux | | | |
| SiN | PC | | Linux | | | |
| Star Wars: Dark Forces | PC | 1.0L Build 1 | Star Wars Masterpieces | | 8031831 | |
| Star Wars: Empire at War | PC | 1.00.35517 | Demo | | 8330730 | |
| Star Wars: Jedi Knight: Dark Forces II | PC | 1.0 | Star Wars Masterpieces | | 9991130 | |
| Star Wars: Making Magic | PC | QA1.03 | Star Wars Masterpieces | | 8031835 | |
| Star Wars: Rebel Assault II: Encounter on Dreighton | PC | WD1.09 | Star Wars Masterpieces, Bundle Version OEM | | 644030 | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sam & Max Hit the Road | PC | | Original | | 634430 | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original, Rerelease | | | |
| Spy Kids 3-D: Game Over | PC | | Original | | I6100 | |
| Star Reach | PC | | Original | | CD-ICD-050-0 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051832 | |
| Supercow | PC | | Original | | P/N 61261-CD | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Soccer | PC | | Wendy's Kids' Meal | | | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| Shopmania | PC | | Original | | P/N 61227-CD | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Silent Hunter III | PC | 1.4 | Encore | | | |
| Sniper: Art of Victory | PC | | Original | | | |
| Snowmobile Racing | PC | | Original | | 04-17527CD | |
| Supreme Commander 2 | PC | | Original | | | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.11 | Rerelease | | GAG744BE-CD | |
| Super Solvers: Spellbound! | PC | 1.11 | Rerelease | | SBO744BE-CD | |
| Street Sports: Jammit | PC | | Super 16 CD Pak Volume 2 | | MQ 13-004-166 | |
| The Sims 2: Insider Preview CD | PC | | Original | | 1625207 | |
| The Sims 2: Double Deluxe (Bonus DVD) | PC | | Original | | 1597027 | |
| Strange Cases: The Tarot Card Mystery / Strange Cases: The Lighthouse Mystery | PC | | The Best of Big Fish Games | | 33364101US | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Samantha Swift and the Golden Touch Samantha Swift Bundle | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Scrabble Complete | PC | | Original, Monopoly & Scrabble Complete, Scrabble Complete/Jeopardy 2003 | | 11290-CD, Part # 23970CD | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Still Life 2 | PC | 1.0 | Original | | 16740-DVD | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims Castaway Stories | PC | 1.0 | Original | | 1575007 | |
| Sacra Terra: Angelic Night | PC | | Original | | | |
| Surface: Mystery of Another World | PC | | Collector's Edition | | 33418010US | |
| Stray Souls: Dollhouse Story | PC | | Original | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 1) | PC | 1.13.0.135 | Original, Slim Case | | 1537107 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 2) | PC | 1.13.0.135 | Original, Slim Case | | 1537117 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.286 | Rerelease | | 1491727 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.286 | Rerelease | | 1491737 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| Slingo | PC | | Original | | 99310 | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Stronghold | PC | 1.00 | Slash Corporation | | | |
| Stanley's Sticker Stories | PC | 1.04 | Original | | 381428-CD4/I083ha | |
| Sudoku Master | PC | 1.0 | Original | | 02-0950-10 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims Medieval | PC | 1.0.286.00001 | Limited Edition | | 1945407 | |
| The Sims Medieval: Pirates & Nobles | PC | 2.0.109.00001 | Original | | 1962507 | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Super Solvers Reading Ages 9-12 | PC | | Original | | SMR744AE-CD | |
| Slingo 2-Pack | PC | | Original | | | |
| Slingo Quest | PC | 0.0.0.104 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Collector's Edition | | 33369101US | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| SWAT: Career Pack (Disc 4) (Police Quest: SWAT) | PC | | Original | | | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Starsiege | PC | 1.02 | Rerelease | | | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Star Wars: X-Wing vs. TIE Fighter (Master Game Disc) | PC | 1.00 | Original | | 2081830 | |
| The Sci-Fi Collection | PC | | Original | | | |
| The Sims | PC | | Bundle Version Gateway OEM | | 1500827 | |
| Star Wars: X-Wing vs. TIE Fighter (Master Game Disc) | PC | 1.00 | Star Wars: X-Wing vs. TIE Fighter + Balance of Power | | 2088130R1 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 2.0A | Star Wars: X-Wing vs. TIE Fighter + Balance of Power | | 2088131R1 | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Original | | CD-ICD-016-0 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.932 | Original | | 1472607, 1472610 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.932 | Original | | 1472610, 1472617 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | 1472627 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.932 | Original | | 1472637 | |
| Snap! Subtraction: Ages 5-8 | PC | | Original | | | |
| Star Wars: Galactic Battlegrounds (Disc 1) (Install) | PC | 1.0 | Original | | 8531830 | |
| Star Wars: Galactic Battlegrounds (Disc 2) (Play) | PC | 1.0 | Original | | 8531831 | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| Syberia (Disc 1) | PC | 1.0 | Game of the Year Edition | | PC37820JC | |
| Syberia (Disc 2) | PC | 1.0 | Game of the Year Edition | | PC37920JC | |
| Syberia (Bonus CD) | PC | 1.0 | Game of the Year Edition | | PCO379CDB | |
| Senha N. 1 | PC | | | | | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| Starflight 2: Trade Routes of the Cloud Nebula | PC | | Top Ten Pak II | | 7588 | |
| Sabrina the Teenage Witch: Brat Attack | PC | | Original | | S02560 | |
| Snoopy's Campfire Stories | PC | | Original | | | |
| Syberia II (Disc 1) | PC | 1.0 | Viva Media Adventure Anthology | | | |
| S²: Silent Storm (Disc 1) | PC | 1.0 | Original | | 28015-CD1 | |
| S²: Silent Storm (Disc 2) | PC | 1.0 | Original | | 28015-CD2 | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | Gold Edition | | | |
| S³: Silent Storm: Sentinels | PC | 1.1 | Gold Edition | | | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | 1015007 | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shape Shifter | PC | | Original | | | |
| Switchball | PC | | Original | | S7275110 | |
| Sid Meier's Civilization: Beyond Earth | PC | | Original | | 41403-1 | |
| SimCity 2000 Special Edition | PC | | Original | | 0126-000-0601-A | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Science Blaster Jr. | PC | | Original | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| Sid Meier's SimGolf | PC | | Rerelease | | 1641547 | |
| Sierra's School House: Math (Disc 1) | PC | | Original | | | |
| Sierra's School House: Math (Disc 2) | PC | | Original | | | |
| SimCoaster | PC | | Rerelease | | 14257?7 | |
| Smart Games: Challenge 1 | PC | | Original | | P/N:DSGC1CD0001 | |
| Spell It Deluxe | PC | | Original | | | |
| Spy Fox in "Dry Cereal" | PC | 2.00 | Original | | Part #04-00000H1407 | |
| StarFlyers: Royal Jewel Rescue | PC | 1.0 | Original | | 381547A-CD | |
| Storybook Weaver Deluxe | PC | 1.1 | Original | | Product #HCD642 | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | #SBW744BE-CD | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Super Solvers: Spellbound! | PC | 1.1 | Rerelease | | | |
| Street Legal | PC | | Original | | 30975.101.US | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Sudoku Ball: Detective | PC | 1.1 | Original | | | |
| Snap! Pool Perfect Pool | PC | 1.1 | Original | | | |
| Survivor Ultimate | PC | 1.00.28 | Original | | Part # 23411CD | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Original | | GAG744AE-CD | |
| The Starfire Soccer Challenge | PC | | Original | | 109-10-2000 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Sorority House: An Interactive Game of Hide and Peek | PC | 1.0 | Original | | | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Storybook Weaver Deluxe | PC | 1.0 | Original | | | |
| Storybook Weaver Deluxe 2004 | PC | 3.0 | Original | | 483050-CD | |
| Super Solvers: Midnight Rescue! | PC | 1.12 | Rerelease | | CSM744BE-CD | |
| A Steven Spielberg Film: Minority Report: Bonus CD-ROM! | PC | | Original | | | |
| Solitaire Master 2 | PC | 2.1 | Original | | 02-6306-10 | |
| Swift Classics Card Games for Windows | PC | | Cosmi | | CDR 720 OD1, SJ 041001 G | |
| Snap Dragon | PC | 1.0 | Original | | | |
| The Sims 4: Island Living | PC | | Original, Rerelease | | 3765703401, 3765703402 | |
| Solitaire Antics Ultimate | PC | 1.0.3L | Original | | | |
| Stonekeep (Interactive Preview) | PC | 1.0 | Demo | | CD-ICD-190-0 | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Rerelease | | | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Strike Commander / Wing Commander: Privateer | PC | | Special CD-ROM Edition | | 1009121 | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Stronghold | PC | 1.1 | Original | | | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Smilingüido em: Desafio na Floresta | PC | | Original | | | |
| Soccer Kid Soccer Kid: Feets of Fury!! | PC | | Original | | D134 | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Original | | GAG744AE-CD | |
| Spy Fox in "Dry Cereal" | PC | | Rerelease | | Part # 0001407 | |
| Stellar 7 | PC | | Original | | | |
| Strategy Games of the World | PC | 1.2 | Bundle Version IBM OEM | | P/N 75H9348 | |
| Save Planet Polluto | PC | 1.0 | Original | | | |
| Scholastic's The Magic School Bus Explores Inside the Earth | PC | | Original | | 0396 Part No. 66556 | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Super Bubble Pop | PC | 1.0 | Original | | 14-9009-10 | |
| Sesame Street: Numbers | PC | | Original | | | |
| Super Solvers: Spellbound! | PC | 1.12 | Rerelease | | SBO744CE-CD | |
| Storybook Weaver Deluxe | PC | 1.2 | Rerelease | | HCD642-CD | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | SBW744DE-CD | |
| Spore | PC | | Original | | 1535207 | |
| Slingo | PC | | Oregon Lottery | | | |
| Slingo: Wild 7's | PC | | Oregon Lottery | | | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Saddle Up with Pippa Funnell: Equestrian Champion | PC | | Original | | 782650-CF | |
| Switchball | PC | 1.0 | Demo | | V536 15G091171100 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | Original | | 25766CD2 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | Original | | 25766CD3 | |
| Silent Hunter | PC | 1.0.324 | Original | | | |
| Star Trek: Starship Creator Warp II | PC | 1.0 | Original | | | |
| Sony E3 2004: Press Information | PC | | Press Kit | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Sanitarium (Disc 1) | PC | 1.00 RC15 / Build 836 | Original | | | |
| The Stronghold Collection | PC | | Original | | 31684-1 | |
| Sins of a Solar Empire | PC | | Rerelease | | | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Snoopy vs. the Red Baron | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 1) (Daria's Inferno / Who Wants to Beat Up a Millionaire) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 2) (I See Sue... the T. Rex / Amazons & Aliens / Cheerios: Playtime) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 3) (How Many Bugs in a Box? / More Bugs in Boxes / Jim Henson's Muppet Babies: Toyland Train / Miss Spider's Tea Party) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 4) (Forbes: Corporate Warrior / Starwebs: Web Shop / Writing Tutor / Complete Idiots Guide: Marketing Materials Maker) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 5) (S&S Encyclopedia / Typing Tutor 12) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 6) (Women's Fitness / Christina Aguilera: Follow Your Dreams) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 8) (Garfield: Mad About Cats / Money Town) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 9) (Darkened Skye: Disc 1 / Zoboomafoo with the Kratt Brothers Animal Kids) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 10) (Deer Avenger / Ski-Doo X-Team Racing) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 11) (Pearl Harbor: Zero Hour / Real War) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 12) (S&S Encyclopedia of Science / Curious George: Reads, Writes and Spells) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 13) (Multimedia Billiards / Astrology Starscopes / Music Match Juke Box Deluxe 6.1 / Extreme Chess / Typing Tutor Jr. / Bumper Wars) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 14) (Darkened Skye: Disc 2) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 18) (M&M's: The Lost Formulas) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 21) (Mob Rule) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 22) (Richard Scarry's: Busy Town) | PC | 2.0 | Original | | | |
| Systemax Ultimate Software Collection (Disc 26) (Sabrina, the Teenage Witch: Brat Attack) | PC | | Original | | | |
| Systemax Ultimate Software Collection (Disc 27) (Star Trek: Deep Space Nine - The Fallen) | PC | | Original | | | |
| SkyMaze X3D SkyMaze | PC | | X3D | | | |
| Supreme Commander | PC | | Original | | P/N: 120904-B | |
| Star Wars: Battlefront | PC | 1.2 | Cosmi | | DVD282D1; SJ032011 | |
| Star Wars: Empire at War: Forces of Corruption | PC | 1.00.55911 | Original | | 7131930 | |
| Spy Kids Learning Adventures: The Candy Conspiracy | PC | | Original | | 03962 | |
| Spy Kids Learning Adventures: The Nightmare Machine | PC | | Original | | 03963 | |
| Silent Hunter 4: Wolves of the Pacific Silent Hunter 4: Wolves of the Pacific: U-Boat Missions | PC | 1.5 | Gold Edition | | 684589-DVD1 | |
| Strategic Command: European Theater | PC | 1.0 | Original | | | |
| Sacred (Disc 1) | PC | 1.8 | Rerelease | | 10153-CD1 | |
| Sacred (Disc 2) | PC | 1.8 | Rerelease | | 10153-CD2 | |
| Silent Hunter | PC | 1.0 | Rerelease | | WWD144AE-CD | |
| Steel Panthers III: Brigade Command: 1939-1999 | PC | 1.0 | Original | | 2218010-590001 | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| Steel Panthers III: Campaign Disk | PC | | Original | | 2220210-590001 | |
| Sid Meier's Pirates! (Disc 1) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 2) | PC | | Rerelease | | | |
| Sanctum: Oppositions / Cybertown | PC | | Original | | | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Sacred Rings (Disc 1) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 2) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 3) | PC | 1.0 | Original | | PCO466CD | |
| The Sacred Rings (Disc 4) | PC | 1.0 | Original | | PCO466CD | |
| SimFarm SimFarm: SimCity's Country Cousin | PC | | Original | | 0003-000-0612-A | |
| Saints Row 2 | PC | | Original | | | |
| Smart Steps: Kindergarten | PC | | Rerelease | | P/N: LDSMASTKIJ | |
| Sweet Tooth To Go Sweet Tooth Deluxe | PC | 1.1R | Original | | 1586807 | |
| The Secret of Margrave Manor | PC | | Original | | | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Star Miner: Battle for Supremacy Asteroid Miner | PC | 1.30 FULL | Pocketware | | #9 | |
| Smashing Reversi Reversi | PC | | Pocketware | | #11 | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Super Lucky's Tale (Disc 1) | PC | | Original | | | |
| Super Lucky's Tale (Disc 2) | PC | | Original | | | |
| SuperBike Racing SuperMoto Racing | PC | | Covermount | | | |
| Soultrap | PC | | Original | | | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| Super Trailer City Trailer Park Tycoon | PC | 1.0.0.1 | Covermount | | | |
| Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |
| Star Wars: Shadows of the Empire | PC | 1.0 | Rerelease | | 646130 | |
| The Sims 2: Double Deluxe The Sims 2: Store Edition | PC | 2.0 | Rerelease | | 1597037 | |
| The Sims 2: Best of Business Collection | PC | 2.0 | Original | | 1685507 | |
| The Sims 2: Fun with Pets Collection | PC | 2.1 | Original | | 1685607 | |
| The Sims 2: University Life Collection | PC | 2.0 | Original | | 1685207 | |
| Sammy's Science House | PC | 1.1 | Original | | | |
| Stellar 7 | PC | | 5 Ft 10 Pak In A Box Volume One | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | 10049 | |
| Sport Image: World Cup 1994 | PC | 2.0 | SoftKey | | WCF344AE-CD | |
| Super Puzzle Fighter II Turbo | PC | | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Sherlock Holmes: Consulting Detective: Vol. I Sherlock Holmes: Consulting Detective: Vol. 1 | PC | | 5 ft. 10 PAK Vol. 2 | | | |
| Star Wars: Pit Droids | PC | | Scholastic | | P/N 9401321C | |
| SSI Strategy Collection: Critic's Choice Ultimate Domain / Serf City / Archon Ultra / Dark Legions / Chessmaster 3000 | PC | 1.0 | Original | | | |
| Starship Troopers | PC | 0.3.2.69 | Original | | P/N 21121-5 | |
| Space Colony | PC | | Original | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Stardew Valley | PC | 1.4.5 | Fangamer | | | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| SpaceChem | PC | 1011 | Original | | | |
| Survival: The Ultimate Challenge | PC | 1.0 | Original | | 31209.101.US | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: Holiday Edition (Disc 2) | PC | 1.0.0.1048 | Original | | 1518917 | |
| The Sims 2: Holiday Edition (Disc 3) | PC | 1.0.0.1048 | Original | | 1518927 | |
| The Sims 2: Holiday Edition (Disc 4) | PC | 1.0.0.1048 | Original | | 1518937 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | Original | | 1672907 | |
| Suncom Technologies Presents: 10 Hit Games by Apogee | PC | | Original | | 63-0647 | |
| Super Solvers: Spellbound! | PC | 1.1 | Rerelease | | SBO744AE-CD | |
| State of Decay: Year-One Survival Edition | PC | | Original | | | |
| Space Jam | PC | 1.00 | Original | | | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Super GameHouse Collection Super Collapse! / Super Glinx! / Super Nisqually | PC | | MacPlay | | | |
| Star Wars Galaxies: The Complete Online Adventures (Disc 1) | PC | | Original | | 8131830 | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Spacebound Space Bound | PC | | Original | | | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 Rev.1 | |
| Shadow Man | PC | | Demo | | | |
| Sierra's Sneak Peeks 2 | PC | | Demo | | | |
| Star Wars Galaxies: 10-Day Trial | PC | | Original | | 8330530 | |
| Street Fighter IV | PC | 1.0.0.1 | Original | | SYX26084GM | |
| So Who's Dr. Rabbit? | PC | | Original | | | |
| Sacred (Disc 1) | PC | 1.2.0.10 | Original | | 28302-CD1 v1.0 | |
| Sacred (Disc 2) | PC | 1.2.0.10 | Original | | 28302-CD2 v1.0 | |
| Space Colony (Interactive Demo) | PC | | Demo | | | |
| Star Trek: Deep Space Nine: The Fallen (Demo and Trailer) | PC | 11-2000-a | Demo | | | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |