Region | Title | System | Version | Edition | Languages | Serial | Status |
| Rune | PC | 1.00 | Original | | | |
| Return to Mysterious Island (Disc 2) | PC | 1.0 | Original | | PCO422CD | |
| Return to Mysterious Island (Disc 1) | PC | 1.0 | Original | | PCO422CD | |
| Red Baron II | PC | 1.0.0.0 | X:Treme Flight Pack | | | |
| Red Baron II | PC | 1.0.0.0 | Original | | | |
| RPG Game Pack: Dungeon Lords / Gothic 3 RPG Double Pack | PC | 2.0 | Original | | DVD559CDM | |
| Red Faction (Disc 1) | PC | 1.0 | Original | | | |
| Riddle of the Sphinx: An Egyptian Adventure (Disc 3) | PC | 1.0, 1.1 | Original, Rerelease | | | |
| Riddle of the Sphinx: An Egyptian Adventure (Disc 2) | PC | 1.0 | Original | | | |
| Riddle of the Sphinx: An Egyptian Adventure (Disc 1) | PC | 1.0 | Original | | | |
| Railroad Tycoon II | PC | 1.02 | Original | | | |
| Rama (Disc 3) | PC | 001.000.000 | Original | | 836924330/S692145 | |
| Rama (Disc 2) | PC | 001.000.000 | Original | | 836924330/S692145 | |
| Rama (Disc 1) | PC | 001.000.000 | Original | | 836924330/S692145 | |
| The Roberta Williams Anthology (Disc 4) | PC | | Original | | | |
| The Roberta Williams Anthology (Disc 3) | PC | | Original | | | |
| The Roberta Williams Anthology (Disc 2) | PC | | Original | | | |
| The Roberta Williams Anthology (Disc 1) | PC | | Original | | | |
| Reel Deal Slots: Ghost Town (Disc 2) | PC | 1.3 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 2) | PC | 1.3 | Original | | | |
| Reel Deal Slots: Mystic Forest (Disc 1) | PC | 1.3 | Original | | | |
| Reel Deal Slots: Ghost Town (Disc 1) | PC | 1.3 | Original | | | |
| Ring (Disc 4) | PC | | Original | | 378217-CD4 | |
| Ring (Disc 3) | PC | 1.0 | Original | | 378217-CD3 | |
| Ring (Disc 2) | PC | 1.0 | Original | | 378217-CD2 | |
| Ring (Disc 1) | PC | 1.0 | Original | | 378217-CD1 | |
| Reel Deal Casino: Gold Rush (Disc 2) | PC | 1.4 | Original | | | |
| Reel Deal Casino: Gold Rush (Disc 1) | PC | 1.4 | Original | | | |
| Reel Deal Slots: Nickels & More! | PC | 1.4 | Original | | | |
| Reel Deal Slots: 2nd Vol. | PC | 1.4 | Original | | | |
| Reel Deal Slots: Nickel Alley | PC | 1.1 | Original | | | |
| Red Baron | PC | | SierraOriginals | | #S648431 | |
| Redneck Rampage | PC | | Original | | CD-ICD-474-0 | |
| Riven: The Sequel to Myst (Disc 5) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD5 | |
| Riven: The Sequel to Myst (Disc 4) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD4 | |
| Riven: The Sequel to Myst (Disc 3) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD3 | |
| Riven: The Sequel to Myst (Disc 2) | PC | | Rerelease, Ages of Myst | | 650324-CD2 | |
| Riven: The Sequel to Myst (Disc 1) | PC | 1.03 | Rerelease, Ages of Myst | | 650324-CD1 | |
| Roberta Williams' Laura Bow: The Dagger of Amon Ra The Dagger of Amon Ra | PC | 1.1 | Original | | | |
| Runaway: The Dream of the Turtle | PC | 1.3 | Rerelease | | | |
| Ringworld: Revenge of the Patriarch | PC | 1.00 | Original | | | |
| Resident Evil 5 | PC | | Original | | | |
| Resident Evil 4 | PC | 1.0 | Original | | 683117-DVD | |
| Resident Evil 3: Nemesis | PC | | Original | | | |
| Resident Evil 2 (Disc 2) | PC | | Platinum | | | |
| Resident Evil 2 (Disc 1) | PC | | Platinum | | | |
| Resident Evil | PC | | Original | | DSK# 83123 | |
| Red Baron: Ace of the Sky | PC | | Red Baron Promo | | | |
| Riven: The Sequel to Myst | PC | 1.2 | 10th Anniversary DVD Edition | | 651116-DVD2 | |
| Realms of the Haunting (Disc 4) | PC | 3.983 | Original, Limited Edition Director's Cut | | CD-ICD-196-3 | |
| Realms of the Haunting (Disc 3) | PC | 3.983 | Original, Limited Edition Director's Cut | | CD-ICD-196-2 | |
| Realms of the Haunting (Disc 2) | PC | 3.983 | Original, Limited Edition Director's Cut | | CD-ICD-196-1 | |
| Realms of the Haunting (Disc 1) | PC | 3.983 | Original, Limited Edition Director's Cut | | CD-ICD-196-0 | |
| Risk: The Game of Global Domination | PC | | Original, Risk: Gold Edition | | 99003 | |
| Rocket Jockey | PC | | Original | | 11009 | |
| Rollcage | PC | | Original | | 24421.101.US | |
| Relentless: Twinsen's Adventure | PC | 1.0 | CD-ROM Classics: Gold Edition | | 5695 | |
| Realms of Arkania Trilogy: Blade of Destiny + Star Trail | PC | 3.09 / C2.00 | Original | | | |
| Redneck Rampage: The Early Years | PC | | SoftKey (Special Edition) | | RED144AE-CD | |
| Road Rash | PC | 1.0A | CD-ROM Classics | | 5995 | |
| Return to Krondor (Disc 1) Raymond E. Feist's Return to Krondor | PC | 1.00.5 | Original | | | |
| Return to Krondor (Disc 2) Raymond E. Feist's Return to Krondor | PC | 1.00.5 | Original | | | |
| Ripper (Disc 2) | PC | | | | | |
| Ripper (Disc 1) | PC | | | | | |
| Road & Track Presents: The Need for Speed SE | PC | | CD-ROM Classics, Rerelease | | 5936, 1162107 | |