Region | Title | System | Version | Edition | Languages | Serial | Status |
| Saints Row: The Third (Disc 1) | PC | | Original | | | |
| Saints Row: The Third (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| The Settlers: Heritage of Kings | PC | 1.01.0163 | Original | | 682011-DVD | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| Sid Meier's Civilization IV (Disc 1) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.6 | |
| Sid Meier's SimGolf | PC | | Rerelease | | 1641547 | |
| The Sims 3: Diesel Stuff The Sims 3: Diesel for Successful Living Stuff | PC | 14.0.48.017001 | Original | | 1968807 | |
| The Sims 3: Fast Lane Stuff | PC | 5.0.44.008001 | Original | | 1950207 | |
| The Sims 3: Katy Perry Sweet Treats | PC | | Original | | 1979807 | |
| The Sims 3: Master Suite Stuff | PC | 11.0.84.014001 | Original | | 1962307 | |
| The Sims 3: Outdoor Living Stuff | PC | 7.0.55.010001 | Original | | 1950307 | |
| The Sims 3: Pets (Expansion Pack) | PC | | Original, Limited Edition | | 1962207 | |
| The Sims 3: Seasons (Expansion Pack) | PC | | Original, Limited Edition | | 1978303301 | |
| Ski Park Manager 2003: Gold Edition Val d'Isère Ski Park Manager 2003: Gold Edition | PC | | | | 71102221 | |
| Sniper: Ghost Warrior 3 (Disc 1) | PC | | Season Pass Edition | | TCIU01221UND | |
| Sniper: Ghost Warrior 3 (Disc 2) | PC | | Season Pass Edition | | TCIU01221UND2 | |
| Sniper: Ghost Warrior 3 (Disc 3) | PC | | Season Pass Edition | | TCIU01221UND3 | |
| Sniper: Ghost Warrior 3 (Disc 4) | PC | | Season Pass Edition | | TCIU01221UND4 | |
| Soldiers of Anarchy | PC | | Original | | S5280010 | |
| Star Defender III | PC | | Original | | CD001697 | |
| StarCraft II: Heart of the Swarm | PC | | Original | | | |
| StarCraft II: Legacy of the Void (Disc 1) | PC | | Original | | | |
| StarCraft II: Legacy of the Void (Disc 2) | PC | | Original | | | |
| StarCraft II: Wings of Liberty | PC | | Original | | | |
| StarCraft II: Wings of Liberty | PC | | Original, Collector's Edition | | | |
| Stolen (Disc 1) (Game Disc) Stolen: Infiltrate · Steal · Vanish | PC | | Original | | | |
| Stronghold 2 (Disc 2) (Play) Firefly Studios' Stronghold 2 | PC | | Original | | | |
| Stronghold 3 | PC | | Original | | 50070-LBL | |
| The Sudoku Challenge! Collection | PC | | Original | | | |
| Superbike 2000 EA Sports: Superbike 2000 | PC | | CD-ROM Classics | | 1215007 | |
| SWAT 3: Close Quarters Battle | PC | 1.4 | Elite Edition | | | |
| Space Engineers | PC | | Limited Edition | | | |
| Super Lucky's Tale (Disc 1) | PC | | Original | | | |
| Super Lucky's Tale (Disc 2) | PC | | Original | | | |
| Sid Meier's Civilization V | PC | | Original, Special Edition | | 31817-1 | |
| SimCity | PC | 1.0 | Original, Limited Edition | | 1971403401 | |
| The Sims 4 (Disc 1) | PC | 1.0 | Limited Edition | | 7303703301, 7303703303 | |
| The Sims 4 (Disc 2) | PC | 1.0 | Limited Edition | | 7303703302, 7303703401 | |
| The Sims 4: Discover University (Expansion Pack) | PC | | Original | | 3765903401 | |
| The Sims 3 | PC | 1.42.130.019037 | The Sims 3 Starter Pack | | 1539003301 | |
| Spy Kids 3-D: Game Over | PC | | Original | | I6100 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| Sid Meier's Civilization VI | PC | | Original | | 41829-1 | |
| Sid Meier's Civilization V: Gold Edition | PC | | Original | | 41252-1 | |
| Sid Meier's Civilization: Beyond Earth | PC | | Original | | 41403-1 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | | |
| Spintires Spintires: Offroad Truck Simulator | PC | | Original | | | |
| SimCity Societies Destinations | PC | 1.0 | SimCity Box | | 1907307 | |
| Spore | PC | 1.0 | Galactic Edition | | 1908007 | |
| Spore: Galactic Adventures | PC | 1.0 | Original | | 1535407 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | MXB08803894CD1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | MXB08803894CD2 | |
| Skylanders: Spyro's Adventure | PC | 1.0 | Starter Pack | | 33366010US | |
| Saints Row 2 | PC | | Original | | | |
| Los Sims: Superstar (Disc 1) | PC | 1.80 | EA Classics | | MXS08004759D1 | |
| The Sims Medieval | PC | 1.0.286.00001 | Limited Edition | | 1945407 | |
| The Sims Medieval: Pirates & Nobles | PC | 2.0.109.00001 | Original | | 1962507 | |
| S²: Silent Storm (Disc 1) | PC | 1.0 | Original | | 28015-CD1 | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | Gold Edition | | | |
| S³: Silent Storm: Sentinels | PC | 1.1 | Gold Edition | | | |
| Sabrina the Teenage Witch: Brat Attack | PC | | Original | | S02560 | |
| Sacred (Disc 1) | PC | 1.8 | Rerelease | | 10153-CD1 | |
| Sacred 2 (Disc 1) | PC | | Original | | | |
| Sacred Gold (Disc 1) | PC | 2.24 | Original | | 10130-CD1 | |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Sammy Soza Softball Slam | PC | | Original | | PCD-5048-001 | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Scarface: The World Is Yours | PC | 1.00.1 | Original | | | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shadow Man | PC | | Original | | | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Sheep | PC | 1.00.000 | Original | | | |
| ShellShock: Nam '67 | PC | 1.00 | Original | | MSHOCPUS01 | |
| Sherlock Holmes Chronicles | PC | 1.0 | Original | | DVD732CD | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Sherlock Holmes: Nemesis (Disc 1) | PC | 1.00.0777 | Original | | PCO589CD1, SNY 1.0 | |
| Sherlock Holmes: The Awakened | PC | 3.0 | Original | | Art. Number PF0903/US2 | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| The Ship | PC | | Original | | | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | 798727 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | 798707 | |
| Shogun: Total War: The Mongol Invasion Shōgun: Total War: The Mongol Invasion | PC | 1.00 | Original | | 1430907 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition | | Part # 24356CD1 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.3 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III: Play the World | PC | 1.01f | Original | | Part # 24115CD | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD2 | |
| Sid Meier's SimGolf | PC | 1.01 | EA Classics | | CD 796 | |
| Sid Meier's SimGolf | PC | 1.0 | Sim Mania 2 | | 1277387 | |
| Sid Meier's SimGolf | PC | 1.01 | Rerelease | | 1434917 | |
| Silent Hill 2 (Disc 1) | PC | 1.0 | Original | | Part Number 23429/23435-1 | |
| Silent Hunter III | PC | 1.0 | Original | | 681953-DVD | |
| Silent Hunter: Wolves of the Pacific | PC | 1.2.0.0 | Original | | 683438-DVD1 | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| SimCity 3000 Unlimited | PC | | Rerelease | | 1446307, 1641507 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Scholastic | | 1500907 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | 1457307 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | 1457317 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | | SimCity Box | | 1907327 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | SimCity Box | | 1907327 | |
| SimCity 4: Rush Hour | PC | 1.0 | Original | | 1472207 | |
| SimCoaster | PC | | Original | | 1425707 | |
| SimCoaster | PC | | Scholastic | | 14257?7 | |
| SimCoaster | PC | | Sim Mania 2, The Kids Collection, Rerelease | | 1242617, 1246307 | |
| SimCoaster | PC | | Rerelease | | 14257?7 | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | Original | | S7213210 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1005 | Rerelease | | 1472647 | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | 1536607 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.312 | Original | | 1497007 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.377 | Rerelease | | 1497027 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 3: Generations (Expansion Pack) | PC | 1.0.0.1 | Original, The Sims 3 Expansion Bundle | | 1957307 | |
| The Sims 3: Hidden Springs | PC | | Original, The Sims 3: Worlds Bundle | | 1979707 | |
| The Sims 3: High-End Loft Stuff | PC | 0.2.0.84 | The Sims 10th Anniversary | | 1941507 | |
| The Sims 3: Into the Future (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7308903401 | |
| The Sims 3: Island Paradise (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7301203301 | |
| The Sims 3: Late Night (Expansion Pack) | PC | 0.2.0.125 | Original, The Sims 3 Starter Pack | | 1915003301 | |
| The Sims 3: Town Life Stuff | PC | | Original | | 1957907 | |
| The Sims 3: University Life (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 1980803301 | |
| The Sims 3: World Adventures (Expansion Pack) | PC | 0.2.0.56 | Original, The Sims 3 Expansion Bundle | | 1539307 | |
| The Sims Carnival: SnapCity | PC | 0.029 | SimCity Box | | 1907347 | |
| The Sims Mandrake Linux Gaming Edition (The Sims for Linux) | PC | | Linux (Mandrake Linux Gaming Edition) | | | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457647 | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.1 | Original, Expansion Collection Volume Two, Mega Deluxe | | 1439827 | |
| The Sims: House Party (Expansion Pack) | PC | | Double Deluxe, Expansion Collection Volume One, Mega Deluxe | | 1446107 | |
| The Sims: House Party (Expansion Pack) | PC | 1.0 | Original | | 1431307, 1431317 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | | Expansion Collection Volume Two | | 1472007 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1472007 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | | | | 1462607 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462607 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459507 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| The Sims: Vacation (Expansion Pack) | PC | | Original | | 1448807 | |
| The Sims: Vacation (Expansion Pack) | PC | | Expansion Collection Volume Three | | 1448807 | |
| SimTheme Park Sim Theme Park | PC | | Gold Edition, Scholastic | | 1403357 | |
| SimTheme Park Sim Theme Park | PC | | Scholastic | | 1403307 | |
| SimTheme Park Sim Theme Park | PC | | Original | | 1403307 | |
| SimTheme Park Sim Theme Park | PC | | Sim Mania 2, The Kids Collection | | 1229827, 1641517 | |
| SimTheme Park Sim Theme Park | PC | | Gold Edition | | 1403337 | |
| SiN Episodes: Emergence | PC | | Original | | 984707 | |
| Sins of a Solar Empire | PC | 1.00 | Original | | | |
| Sniper Elite | PC | | Original | | 40009 | |
| Sniper: Ghost Warrior | PC | | Original | | L0001US | |
| Snoopy vs. the Red Baron | PC | | Original | | | |
| Space Colony | PC | | Original | | | |
| Space Siege | PC | 1.0 | Original | | | |
| Spacebound Space Bound | PC | | Original | | | |
| Spear of Destiny | PC | | Ultimate Game Collection | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Spear of Destiny: Super CD Pack | PC | | Super CD Pack | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| SpellForce | PC | 1.52.64763 | Platinum Edition | | 11121-1DDA | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
| SpellForce: Universe (Disc 1) | PC | 1.52 | Original | | DVD564CD | |
| Spider-Man 3 | PC | | Original | | 33121.101.US | |
| Spider-Man: Friend or Foe | PC | | Original | | 33167.101.US | |
| The Spiderwick Chronicles | PC | 1.0 | Original | | S7270810 | |
| Spore | PC | | Original | | 1535207 | |
| Spore | PC | 1.00.000 | Original | | 1535207 | |
| Spore: Creature Creator | PC | | Original | | 1586407 | |
| Spy Kids: Mega Mission Zone | PC | 3.6.27 | Original | | H3343 | |
| Star Trek: Klingon Academy (Disc 1) | PC | | Original | | CD-C95-856-0 | |
| Star Trek: Klingon Academy (Disc 2) | PC | | Original | | CD-C95-856-1 | |
| Star Trek: Klingon Academy (Disc 3) | PC | | Original | | CD-C95-856-2 | |
| Star Trek: Klingon Academy (Disc 4) | PC | | Original | | CD-C95-856-3 | |
| Star Trek: Klingon Academy (Disc 5) | PC | | Original | | CD-C95-856-4 | |
| Star Trek: Klingon Academy (Disc 6) | PC | | Original | | CD-C95-856-5 | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3241830 | |
| Star Wars: Battlefront II | PC | 1.0 | DVD-ROM | | 3282030 | |
| Star Wars: Battlefront II (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3281830 | |
| Star Wars: Empire at War (Bonus Disc) | PC | | Original, Collector's Edition | | 8541832 | |
| Star Wars: Empire at War | PC | 1.00.35517 | Demo | | 8330730 | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Rerelease | | 8541830R | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Original, Collector's Edition | | 8541830 | |
| Star Wars: Empire at War: Forces of Corruption (Disc 1) | PC | 1.00.55911 | Original | | 7131830 | |
| Star Wars: Empire at War: Gold Pack | PC | 1.0.5.0 | Rerelease | | DVD284D1, SJ102010 | |
| Star Wars: Empire at War: Gold Pack | PC | 1.05.48824 | Original | | 9999830 | |
| Star Wars: Jedi Knight: Jedi Academy (Disc 1) | PC | 1.0 | Original | | 9551830 | |
| Star Wars: Knights of the Old Republic | PC | 1.3.1.0 | Star Wars: Knights of the Old Republic Collection (DVD-ROM) | | 9982530 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.0.0.0 | Original | | 3191830 | |
| Star Wars: Knights of the Old Republic (Disc 1) (Play Disc) | PC | 1.0.0.0 | Original | | 3191830 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords | PC | 2.2.0.0 | Star Wars: Knights of the Old Republic Collection (DVD-ROM) | | 9982531 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Rerelease | | 3261830R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3261830 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 2.00.424 | Original | | 3261830R1 v2.1.0.0 | |
| Star Wars: Republic Commando | PC | | Original | | 3258130, 3258130R | |
| Star Wars: Republic Commando | PC | 1.0 | Star Wars: Fan Favorites I | | 9982132 V1.01.0.1 | |
| Star Wars: Republic Commando (Disc 1) (Play Disc) | PC | | Original | | 3251830 | |
| Star Wars: The Best of PC (Star Wars: Empire at War & Star Wars: Knights of the Old Republic) | PC | 1.0 | Original | | 8101830 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67021 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67021 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | | Original | | 0200 Part Number X05-67023 | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67023 | |
| Starship Troopers | PC | 0.3.2.69 | Original | | P/N 21121-5 | |
| Startopia | PC | 1.00 | Original | | MSTARPUS01 | |
| Steel Soldiers | PC | | Original | | | |
| Still Life (Disc 2) (Play) | PC | 1.0 | Original | | PCO461CD | |
| The Sting! | PC | v2.0e | Original | | ROTHESTING0004USLAB | |
| Strong Bad's Cool Game for Attractive People | PC | 1.5.0.0 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.0 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.1 | Original | | | |
| Stronghold Crusader FireFly Studios' Stronghold Crusader | PC | 1.0 | Original | | | |
| Stubbs the Zombie in Rebel Without a Pulse (Disc 1) | PC | 1.0 | Original | | 11001-1CDA | |
| Sudden Strike | PC | 1.0.0.1 | Original | | 04-22099CD1 | |
| Sudden Strike II | PC | 2.0 | Original | | CDR8000/US2 | |
| The Suffering (Disc 1) | PC | 1.0 | Original | | 28424 CD1 v1.0 | |
| The Suffering: Ties That Bind (Disc 1) | PC | | Original | | | |
| The Sum of All Fears | PC | 1.0.12.0 | Original | | 650362-CD | |
| Super Meat Boy: Ultra Edition | PC | | Original | | | |
| Superbike 2001 | PC | | Original | | 1421707 | |
| SuperPower | PC | 1.0 | | | PC35320JC | |
| SuperPower | PC | 1.1 | Original | | | |
| Supreme Commander | PC | | Original | | P/N: 120904-B | |
| Supreme Commander | PC | 1.0.3189 | Original, Gold Edition | | part # 109050 | |
| Supreme Commander: Forged Alliance | PC | 1.5.0.1 | Original, Gold Edition | | 111603 | |
| SWAT 3: Close Quarters Battle | PC | 1.0 | Original | | | |
| SWAT 3: Close Quarters Battle (Play CD) | PC | 2.0 | Tactical Game of the Year Edition | | | |
| SWAT 3: Close Quarters Battle (Disc 1) (Play Disc) | PC | 2.0 | Tactical Game of the Year Edition: SWAT 4 | | | |
| SWAT 4 (Disc 1) | PC | 1.0 | Original | | | |
| SWAT 4 (Disc 1) | PC | 31973 | Original | | | |
| SWAT 4: The Stetchkov Syndicate | PC | | Original | | | |
| Sweet Tooth To Go Sweet Tooth Deluxe | PC | 1.1R | Original | | 1586807 | |
| Switchball | PC | | Original | | S7275110 | |
| Sword of the Stars | PC | 1.0.12 | Original | | P/N 21133-5 | |
| Syberia (Disc 1) | PC | 1.0 | Original | | | |
| Syberia (Disc 1) | PC | 1.0 | Original | | PC37920JC | |
| Syberia (Disc 1) | PC | 1.0.0.8 | Press Review Copy | | | |
| Syberia (Disc 2) | PC | 1.0 | Original | | PC37920JC | |
| Syberia II (Disc 1) | PC | 1.0 | Original | | 71702221 | |
| Syberia II (Disc 1) | PC | 1.0 | Viva Media Adventure Anthology | | | |
| System Shock 2 | PC | 1.15 | Original | | 796907 | |
| System Shock 2 | PC | 2.3 | Classics | | 1203807 | |
| System Shock 2 시스템 쇼크 2 | PC | 2.3 | Rerelease, EA Classix, Gagyeok Pagoe! | | 796917 | |
| S.T.A.L.K.E.R.: Clear Sky | PC | 1.0 | Original | | ECD950001D | |
| The Saboteur | PC | 1.0 | Original | | | |
| Spider-Man: Web of Shadows | PC | 1.0 | Original | | 33211.101.EF, 33211.101.US | |
| Star Wars: The Force Unleashed II | PC | 1.0 | Original | | 3411830 | |
| Star Wars: The Force Unleashed II | PC | 1.1 | Cosmi | | DVD248D1 v 1.1.0.1 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | PC | 0.0.0.0 | Original | | 12241-1DDA2 | |
| The Sims Carnival: BumperBlast | PC | 1.0.10 | Original | | 1586907 | |
| Star Trek: Voyager: Elite Force | PC | 0.28 | Original, Collector's Edition | | 1000912.101.US | |
| Star Wars: The Old Republic (Disc 1) | PC | 1.0.0.0 | Original | | 1957807 | |
| Sam & Max: Beyond Time and Space | PC | | Original | | 27898CD | |
| Street Fighter IV | PC | 1.0.0.1 | Original | | SYX26084GM | |
| Street Fighter IV | PC | 1.00.3013 | Original, Limited Edition | | | |
| Sonic Riders (Disc 1) | PC | 1.0 | Scholastic | | P/N CDR5047633 | |
| Sonic Riders (Disc 1) | PC | 1.0 | Original | | | |
| South Park: The Fractured But Whole (Disc 1) | PC | | Gold Edition | | UBP60802045-DISC1 | |
| South Park: The Fractured But Whole (Disc 2) | PC | | Gold Edition | | UBP60802045-DISC2 | |
| South Park: The Fractured But Whole (Disc 3) | PC | | Gold Edition | | UBP60802045-DISC3 | |
| South Park: The Stick of Truth | PC | | Original | | 689058-DVD | |
| Shift 2: Unleashed | PC | | Limited Edition | | 1948307 | |
| Syndicate | PC | | Original | | 1922907 | |
| S.T.A.L.K.E.R.: Call of Pripyat | PC | 1.6.02 | Collector's Edition | | | |
| ShellShock 2: Blood Trails | PC | 1.0 | Original | | 5000026211 | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV: Beyond the Sword (Disc 1) | PC | 3.0.3.1 (77541) | Rerelease | | 31173-1.1 | |
| Sid Meier's Civilization IV: Colonization | PC | | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 1) | PC | 1.7.4.0 | Original | | 31183-1.1 | |
| Sid Meier's Civilization IV: Warlords | PC | 2.0 | Original | | 21966-1 | |
| Slave Zero | PC | 1.0 | Original | | 46031-301SZR | |
| Sonic Heroes (Disc 2) | PC | 1.0 | Original | | | |
| Spider-Man: Shattered Dimensions | PC | | Original | | 33355101US | |
| Star Trek: D-A-C | PC | | Cosmi | | CDR164D1 | |
| Star Wars: The Clone Wars: Republic Heroes | PC | 1.0 | Cosmi | | DVD288D1 | |
| Star Wars: The Clone Wars: Republic Heroes | PC | 1.0 | Original | | 3381830 | |
| State of Decay: Year-One Survival Edition | PC | | Original | | | |
| Supreme Commander 2 | PC | | Original | | | |
| South Park | PC | | Original | | | |
| Shogun: Total War: Gold Edition | PC | 1.00 | Total War: Eras | | SYX26218GM1 | |
| Singularity | PC | 1.0 | Original | | 33309101US | |
| State of Emergency | PC | 1.00.0008 | Original | | | |
| Stronghold 3 Gold Stronghold 3: Gold | PC | | Original | | 50080-LBL | |
| Section 8 | PC | | Original | | 50027-LBL | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.0.4140.0 | Scholastic | | P/N DVD5107350 | |
| Sid Meier's Civilization IV (Disc 1) | PC | 1.61 | Game of the Year Edition | | 77875-1.1REA | |
| The Sims 3 | PC | 1.0.631.00001, 0.0.0.11195 | Original, The Sims 3: Deluxe | | 1539007 | |
| Spec Ops: The Line | PC | | Premium Edition | | 41152-1 | |
| Star Wars: Episode III: Revenge of the Sith: Activity Center (Disc 1) | PC | 1.0 | Original | | 682967-CD1 | |
| Star Wars: Episode III: Revenge of the Sith: Activity Center (Disc 2) | PC | 1.0 | Original | | 682967-CD2 | |
| Syberia Collectors Edition: I & II | PC | | Original | | 16660-DVD | |
| Silent Hill 4: The Room | PC | 1.0 | Original | | | |
| SimCity Societies | PC | 1.0 | Original | | 1574507 | |
| The Sims 2 (Game Disk) | PC | 1.0.0.932 | Special DVD Edition | | 1488307 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1022 | Rerelease | | 1472626, 1472666, 1472687 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.932 | Original | | 1472607, 1472610 | |
| The Sims 2: Apartment Life (Expansion Pack) | PC | 1.16.0.179 | Original, Slim Case | | 1907807 | |
| The Sims 2: Best of Business Collection | PC | 2.0 | Original | | 1685507 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 1) | PC | 1.10.0.111 | Original, Slim Case | | 1536707 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original, Slim Case | | 1536717 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original | | 1536717 | |
| The Sims 2: Celebration! Stuff | PC | 1.8.0.64 | Original | | 1564707 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | Original | | 1672907 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | | | 1672927 | |
| The Sims 2: Double Deluxe | PC | | Original | | 1597007 | |
| The Sims 2: Double Deluxe The Sims 2: Store Edition | PC | 2.0 | Rerelease | | 1597037 | |
| The Sims 2: Family Fun Stuff | PC | | Original | | 1515807 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 1) | PC | 1.13.0.135 | Original, Slim Case | | 1537107 | |
| The Sims 2: Fun with Pets Collection | PC | 2.1 | Original | | 1685607 | |
| The Sims 2: Glamour Life Stuff | PC | 1.5.0.121 | Original | | 1520807 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1022 | 2006 Edition | | 1527607 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | 1578207 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | 1578007 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | 1.14.0.72 | Original | | 1578007 | |
| The Sims 2: Mansion & Garden Stuff | PC | 1.17.0.66 | Original | | 1918007 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 1) | PC | 1.7.0.145 | Original, Slim Case | | 1562107 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.286 | Rerelease | | 1491727 | |
| The Sims 2: University Life Collection | PC | 2.0 | Original | | 1685207 | |
| The Sims 4: Island Living | PC | | Original, Rerelease | | 3765703401, 3765703402 | |
| The Sims Castaway Stories | PC | 1.0 | Original | | 1575007 | |
| The Sims Life Stories | PC | 1.0.22.17622 | Original | | 1528207 | |
| The Sims | PC | | Bundle Version Gateway OEM | | 1500827 | |
| The Sims | PC | 1.0 | Original | | 1500807 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims: Pet Stories | PC | | Original | | 1536507 | |
| Star Wars: Battlefront II | PC | 1.0 | Original | | 3281930 | |
| Star Wars: Empire at War: Forces of Corruption | PC | 1.00.55911 | Original | | 7131930 | |
| Stronghold | PC | 1.1 | Original | | | |