Region | Title | System | Version | Edition | Languages | Serial | Status |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | PC | | Rerelease | | | |
| Solid State Pinball: Crystal Caliburn | PC | | Rerelease | | 517-05-232 | |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | PC | | Rerelease | | 517-05-232 | |
| Soldiers of Anarchy | PC | | Original | | S5280010 | |
| Soldiers at War | PC | | Preview | | | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| The Software Toolworks' Star Wars Chess | PC | 1.00 | Bundle Version OEM | | 13-004-060 | |
| The Software Toolworks CD Game Pack | PC | | Original | | | |
| The Software Toolworks CD Deluxe Pack: Version 2 | PC | | Bundle Version Packard Bell OEM | | 2192611-590001 170122 | |
| Software & Document: Master CD for Video Family | PC | 1.20 | Bundle Version Jaton OEM | | | |
| Soft Kill | PC | | Original | | | |
| Sócrates en la Casa del Terror Sócrates en la Casa Embrujada | PC | | Covermount | | | |
| Soccer Score Soccer | PC | | Original | | | |
| Soccer Kid Soccer Kid: Feets of Fury!! | PC | | Original | | D134 | |
| So You Wanna Be a Redneck | PC | | Original | | | |
| So Who's Dr. Rabbit? | PC | | Original | | | |
| Snowboard Park Tycoon | PC | | | | 30983.101.US | |
| Snow Storm | PC | | Original | | 9099 | |
| Snow Sakura | PC | | Original | | GC030 | |
| Snow Drop | PC | | Original | | P-002 | |
| Snoopy's Campfire Stories | PC | | Original | | | |
| Snoopy vs. the Red Baron | PC | | Original | | | |
| SNK Playmore E3 2006 Games | PC | | Press Kit | | | |
| SNK NeoGeo USA Consumer Corporation: E3 2004 Games | PC | | Press Kit | | | |
| Sniper: Path of Vengeance | PC | | Original | | | |
| Sniper: Ghost Warrior 3 (Disc 4) | PC | | Season Pass Edition | | TCIU01221UND4 | |
| Sniper: Ghost Warrior 3 (Disc 3) | PC | | Season Pass Edition | | TCIU01221UND3 | |
| Sniper: Ghost Warrior 3 (Disc 2) | PC | | Season Pass Edition | | TCIU01221UND2 | |
| Sniper: Ghost Warrior 3 (Disc 1) | PC | | Season Pass Edition | | TCIU01221UND | |
| Sniper: Ghost Warrior | PC | | Original | | L0001US | |
| Sniper: Art of Victory | PC | | Original | | | |
| Sniper Elite | PC | | Original | | 40009 | |
| Snap! Subtraction: Ages 5-8 | PC | | Original | | | |
| Snap! Pool Perfect Pool | PC | 1.1 | Original | | | |
| Snap! Pinball | PC | | Original | | | |
| Snap! 400 Word Searches | PC | | Original | | CS-296 | |
| Snap! 3D Bowling | PC | | Original | | | |
| Snap Dragon | PC | 1.0 | Original | | | |
| Smoking Guns Smoking Guns: Shooting Gallery! | PC | 1.0 | Cosmi | | 02-2503-10 | |
| Smilingüido em: Desafio na Floresta | PC | | Original | | | |
| The Smelly Mystery | PC | 1.0 | Original | | 04-12328CD | |
| SMBX + Tak 2 Art | PC | | Press Kit | | | |
| Smart Steps: Kindergarten | PC | 1.0 | Original | | | |
| Smart Steps: Kindergarten | PC | | Rerelease | | P/N: LDSMASTKIJ | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Smart Games: Challenge 1 | PC | | Original | | P/N:DSGC1CD0001 | |
| Small Soldiers: Squad Commander | PC | | | | Product# 99264 | |
| Small Soldiers: Globaltech Design Lab | PC | | | | Product# 99144 | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots from Bally Gaming Masque Slots 3 | PC | 1.0.0 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.2 | Original | | | |
| Slots Featuring WMS Gaming II Masque Slots 8 | PC | 1.0.1 | Original | | | |
| Slots Featuring WMS Gaming | PC | 1.0.3 | Original | | | |
| Slots Dual Pack Best of Slots from Bally Gaming / Best of Slots II | PC | | Original | | | |
| Slots Adventure: War for Olympus | PC | 1.0 | Original | | | |
| Slots 100 | PC | | Cosmi | | CDR712D1, SJ 062001 | |
| Slot City 2 Plus Video Poker | PC | 1.0 | Original | | 7200-CD1 | |
| Slot City Jackpot Games (120 Slot Machines) | PC | | Jackpot Games | | CD-4700 | |
| Slipstream 5000 | PC | | Original | | CN000500028 | |
| Slingo: Wild 7's | PC | | Oregon Lottery | | | |
| Slingo: 15th Anniversary Edition | PC | | Original | | | |
| Slingo Quest | PC | 0.0.0.104 | Original | | | |
| Slingo Mystery: Who's Gold | PC | | Big Fish Games Backup CD | | | |
| Slingo Deluxe Slingo Deluxe Bundle | PC | | Original | | | |
| Slingo 2-Pack | PC | | Original | | | |
| Slingo | PC | | Oregon Lottery | | | |
| Slingo | PC | | Original | | 99310 | |
| Sleepwalker | PC | | Megapak 2 | | 42631-911SWC | |
| Slave Zero | PC | 1.1.6.5I | Premier Action | | 50010-304B02 | |
| Slave Pageant (Game Disc) | PC | | Original | | GC-020 | |
| Slave Pageant (Install Disc) | PC | | Original | | GC-020 | |
| Slater & Charlie Go Camping | PC | 1.000 | SierraOriginals | | | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | 1.01 | Rerelease | | TYN744BE-CD | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | | Original | | WTY744AE-CD | |
| Slam City with Scottie Pippen (Disc 3) (Mad Dog) | PC | | Original | | | |
| SkyTrip America SkyTrip America: An Incredible Ride Through U.S. History! | PC | 1.0 | | | | |
| SkyMaze X3D SkyMaze | PC | | X3D | | | |
| Skylanders: Spyro's Adventure | PC | 1.0 | Starter Pack | | 33366010US | |
| Skylanders: Spyro's Adventure | PC | | Press Kit | | | |
| Skunny Kart Combo | PC | | Original | | | |
| Skunny | PC | 1.0 | Original | | P/N 7149 | |
| The Skins Game at Bighorn | PC | | Original | | CD-MPC-126-0 | |
| Ski Park Manager 2003: Gold Edition Val d'Isère Ski Park Manager 2003: Gold Edition | PC | | | | 71102221 | |
| Sitting Ducks | PC | 1.0 | Rerelease | | | |
| Sitting Ducks | PC | 1.0 | | | | |
| Sins of a Solar Empire: Trinity | PC | | | | | |
| Sins of a Solar Empire: Trinity | PC | | Rerelease | | | |
| Sins of a Solar Empire | PC | 1.165 | Game of the Year Edition | | | |
| Sins of a Solar Empire | PC | | Rerelease | | | |
| Sinkha | PC | | Original | | | |
| Sinistar: Unleashed | PC | | Original | | | |
| Singularity | PC | | Press Kit | | | |
| Sing-Along Kids: Vol. 2 | PC | | | | | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| Sinbad: Legend of the Seven Seas | PC | 1.0 | Original | | Part # 24755CD | |
| SiN Mission Pack: Wages of SiN | PC | 1.03 | Original | | 1000384.101.US | |
| SiN | PC | 1.01 | Rerelease | | 6236 01 | |
| SiN | PC | 1.01 | Original | | 1000076.101.US | |
| SiN | PC | 1.01 | Rerelease | | 6236-01 | |
| SiN | PC | | Linux | | | |
| SiN | PC | | Demo | | DMO-1000076.101.US | |
| SimTunes | PC | | Original | | 0135-000-0601-A | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-A | |
| SimTown | PC | | The Kids Collection | | 1258607 | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-B | |
| SimTheme Park Sim Theme Park | PC | | Scholastic | | 1403307 | |
| SimTheme Park Sim Theme Park | PC | | Original | | 1403307 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Scholastic | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | | Original | | 1640617 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Scholastic | | 1459507 | |
| The Sims: Pet Stories | PC | | Original | | 1536507 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | 1457637 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | 1457627 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 4) | PC | 1.0 | Original | | 1647437 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 3) | PC | 1.0 | Original | | 1647427 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 2) | PC | 1.0 | Original | | 1647417 | |
| The Sims: Complete Collection (Disc 1) | PC | 1.0 | Original | | 1647407 | |
| The Sims Mandrake Linux Gaming Edition (The Sims for Linux) | PC | | Linux (Mandrake Linux Gaming Edition) | | | |
| Los Sims: Superstar (Disc 2) | PC | 1.80 | EA Classics | | MXS08004759D2 | |
| Los Sims: Superstar (Disc 1) | PC | 1.80 | EA Classics | | MXS08004759D1 | |
| The Sims Strategy Guide and SimFan Pack | PC | | Pre-Order Bonus | | 1414407 | |
| The Sims Online: Sampler Disc | PC | | Original | | 4025407 | |
| The Sims Online (Disc 2) | PC | 1.0 | Charter Edition | | 1461527 | |
| The Sims Online (Disc 1) | PC | 1.0 | Charter Edition | | 1461517 | |
| The Sims Castaway Stories | PC | 1.0 | Original | | 1575007 | |
| The Sims Carnival: BumperBlast | PC | 1.0.10 | Original | | 1586907 | |
| The Sims 4: Discover University (Expansion Pack) | PC | | Original | | 3765903401 | |
| The Sims 3: University Life (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 1980803301 | |
| The Sims 3: Outdoor Living Stuff | PC | 7.0.55.010001 | Original | | 1950307 | |
| The Sims 3: Master Suite Stuff | PC | 11.0.84.014001 | Original | | 1962307 | |
| The Sims 3: Katy Perry Sweet Treats | PC | | Original | | 1979807 | |
| The Sims 3: Fast Lane Stuff | PC | 5.0.44.008001 | Original | | 1950207 | |
| The Sims 3: Diesel Stuff The Sims 3: Diesel for Successful Living Stuff | PC | 14.0.48.017001 | Original | | 1968807 | |
| The Sims 3 | PC | | Original | | | |
| The Sims 2: University Life Collection | PC | 2.0 | Original | | 1685207 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | | | | 1497037 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | 1.14.0.72 | Original | | 1578007 | |
| The Sims 2: Kitchen & Bath Interior Design Stuff | PC | | Original | | 1578007 | |
| The Sims 2: Insider Preview CD | PC | | Original | | 1625207 | |
| The Sims 2: Holiday Edition (Disc 4) | PC | 1.0.0.1048 | Original | | 1518937 | |
| The Sims 2: Holiday Edition (Disc 3) | PC | 1.0.0.1048 | Original | | 1518927 | |
| The Sims 2: Holiday Edition (Disc 2) | PC | 1.0.0.1048 | Original | | 1518917 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1048 | Original | | 1518907 | |
| The Sims 2: Holiday Edition (Disc 1) | PC | 1.0.0.1022 | 2006 Edition | | 1527607 | |
| The Sims 2: Happy Holiday Stuff | PC | | Original | | 1527707 | |
| The Sims 2: Double Deluxe The Sims 2: Store Edition | PC | 2.0 | Rerelease | | 1597037 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | Original | | 1672907 | |
| The Sims 2: Deluxe (Bonus DVD) | PC | | The Sims 2: Double Deluxe | | 1597017 | |
| The Sims 2: Celebration! Stuff | PC | 1.8.0.64 | Original | | 1564707 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original | | 1536717 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.1005 | Rerelease | | 1472677 | |
| The Sims 2 (Disc 4) | PC | 1.0 | Original | | 1472637 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.932 | Original | | 1472627 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.1005 | Rerelease | | 1472667 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.1005 | Rerelease | | 1472657 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1005 | Rerelease | | 1472647 | |
| The Sims 2 (Disc 1) | PC | 1.0 | Original | | 1472607 | |
| The Sims 2 | PC | | Press Kit | | | |
| Simon the Sorcerer | PC | 1.00 | Original | | | |
| SimLife SimLife: The Genetic Playground | PC | | Rerelease | | | |
| SimIsle: Missions in the Rainforest | PC | 1.0 | Original | | 0058-030-0901 | |
| SimGolf | PC | 1.0 | Original | | 0093-000-0601-A | |
| SimCoaster: Bonus Disk SimCoaster Extra Value Pack | PC | | | | 4002307 | |
| SimCoaster | PC | | Scholastic | | 14257?7 | |
| SimCoaster | PC | | Rerelease | | 14257?7 | |
| SimClassics: Maxis Collections 2 | PC | | Original | | 0092-000-0601-A | |
| SimClassics: 3 in 1 Pack | PC | | Original | | 0543-000-0601-A | |
| SimCity Enhanced CD-ROM | PC | 1.0 | Rerelease | | CD-ICD-508-0 | |
| SimCity Enhanced CD-ROM | PC | | Rerelease | | CD-ICD-204-0 | |
| SimCity Enhanced CD-ROM | PC | | Original | | CD-ICD-041-0 | |
| SimCity Classic | PC | | Collector's Series | | 0002-000-0612-A | |
| SimCity 4: Rush Hour | PC | 1.0 | Original | | 1472207 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | SimCity Box | | 1907327 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | | SimCity Box | | 1907327 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.0 | Scholastic | | CDR5034957 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | | Original | | 1474007 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Cosmi | | 1474017, CDR123D2 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Cosmi | | 1474007, CDR123D1 | |
| SimCity 4 (Disc 2) | PC | 1.0 | Original | | MXB08803894CD2 | |
| SimCity 4 (Disc 1) | PC | 1.0 | Original | | MXB08803894CD1 | |
| SimCity 3000 Unlimited | PC | 2.0.949 | Scholastic | | 1500907 | |
| SimCity 3000 Unlimited | PC | | Bundle Version Compaq OEM | | 1500907, 239478-001 | |
| SimCity 3000 | PC | 1.2.673.0 | Rerelease | | 1500117 | |
| SimCity 3000 | PC | | Domino's Pizza / Easter Seals | | | |
| SimCity 3000 | PC | | Linux | | | |
| SimCity 3000 | PC | | Pre-Order Bonus | | 4083407 | |
| SimCity 3000 | PC | | Scholastic | | 1500107 | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.0 | Original | | | |
| SimCity 2000 Special Edition | PC | 1.0 | CD-ROM Classics | | 1131107 | |
| SimCity 2000 Network Edition | PC | 1.0.42.0 | Megapak 8 | | 01130-059-0601 | |
| SimCity (Preview Disc) | PC | | Target | | 7298103301 | |
| SimAnt | PC | | Scholastic | | 5710346C SP2 | |
| The Silver Case | PC | 1.01 | Limited Run Games Limited Edition | | | |
| Silver (Disc 2) | PC | 1.08C | | | | |
| Silver (Disc 1) | PC | 1.08C | | | | |
| Silkolene Honda Motocross GP | PC | 1.0 | Original | | 13030 | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.00 | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel | PC | 1.82.42.100 | DVD-ROM | | | |
| Silent Hunter: Wolves of the Pacific | PC | 1.2.0.0 | Original | | 683438-DVD1 | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Original | | 2211110-590004 | |
| Silent Hunter: Commander's Edition | PC | 1.31 | Ultimate Wargame Collection Volume 2: World War II | | 379280-CD2 | |
| Silent Hunter 4: Wolves of the Pacific Silent Hunter 4: Wolves of the Pacific: U-Boat Missions | PC | 1.5 | Gold Edition | | 684589-DVD1 | |
| Silent Hunter | PC | 1.0 | Rerelease | | WWD144AE-CD | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | | |
| Silent Heroes: Elite Troops of WWII | PC | 1.0.29.0 | Original | | | |
| Sierra's Sneak Peeks 2 | PC | | Demo | | | |
| Sierra's School House: Science (Disc 2) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Science (Disc 1) | PC | | Original | | 831614230/S161155 | |
| Sierra's School House: Math (Disc 2) | PC | | Original | | | |
| Sierra's School House: Math (Disc 1) | PC | | Original | | | |
| Sierra's School House: English (Disc 2) | PC | | | | | |
| Sierra's School House: English (Disc 1) | PC | | Original | | | |
| Sierra Super Sampler Sierra On-Line Demos | PC | | | | | |
| Sierra Products Demo America Online featuring Sierra Online | PC | | | | R00482 | |
| Sierra Pro Pilot (Disc 2) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot (Disc 1) | PC | 1.0 | Original | | | |
| Sierra Press Kit | PC | | Press Kit | | | |
| Sierra Holiday Software Sampler | PC | | | | | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| Siege | PC | 1.2 | | | | |
| Sid Meier's SimGolf | PC | | Rerelease | | 1641547 | |
| Sid Meier's SimGolf | PC | 1.01 | EA Classics | | CD 796 | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Sid Meier's Pirates! (Disc 2) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 1) | PC | | Rerelease | | | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Sid Meier's Civilization: Beyond Earth | PC | | Original | | 41403-1 | |
| Sid Meier's Civilization VI | PC | | Original | | 41829-1 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | Original | | 25766CD3 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | Original | | 25766CD2 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition (Rerelease) | | | |
| Sid Meier's Civilization III | PC | 1.29f | Scholastic | | P/N CDR9640733 | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Risk: Gold Edition | | Product # 99227 | |
| Sid Meier's Civilization II | PC | 2.42a | Infogrames Rerelease | | | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42 | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization Chronicles (Disc 2) | PC | | Original | | 31074-1.2 | |
| Sid Meier's Civilization Chronicles (Disc 1) | PC | | Original | | 31074-1.1 | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Shrine Circus Tycoon | PC | | | | 31933.101.US | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek 2: Team Action | PC | 1.0 | Original | | 32789.101.US | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shrek 2 (Final Press Kit) | PC | | Press Kit | | | |
| Shrek 2 | PC | | | | 32585.101.US | |
| Shrak Shrak for Quake | PC | 2.0 | Rerelease | | | |
| Shogun: Total War: The Mongol Invasion Shōgun: Total War: The Mongol Invasion | PC | 1.00 | Original | | 1430907 | |
| Shogun: Total War: Gold Edition | PC | 1.00 | Total War: Eras | | SYX26218GM1 | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | 798727 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Bundle Version Creative Labs OEM | | 1713310341 | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.00 | | | | |
| Shivers Two: Harvest of Souls | PC | 1.0 | Demo | | | |
| Shivers | PC | | Demo | | | |
| The Ship | PC | | Original | | | |
| Shining Soul II + Shining Force Assets Shining Soul 2 + Shining Force Assets | PC | | Press Kit | | | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| Sherlock Holmes: Nemesis (Disc 2) | PC | 1.00.0777 | Original | | PCO589CD2, SNY 1.0 | |
| Sherlock Holmes: Nemesis (Disc 1) | PC | 1.00.0777 | Original | | PCO589CD1, SNY 1.0 | |
| Sherlock Holmes: Consulting Detective: Vol. III | PC | 4 | Original | | CDRM1061930 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 5.1 | 5 ft. 10 PAK Vol. 2 | | CD 7012 SPI | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Rerelease | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Shenmue III | PC | | Backer Exclusive Edition | | | |
| ShellShock: Nam '67 | PC | 1.00 | Original | | MSHOCPUS01 | |
| ShellShock 2: Blood Trails | PC | 1.0 | Original | | 5000026211 | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Shattered Steel | PC | 1.03 | Original | | CD-ICD-201-2 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | | Interactive Preview | | CD-ICD-308-0 | |
| Sharks! An Interactive Journey An Interactive Journey With... Sharks! | PC | | Original | | | |
| Shape Shifter | PC | | Original | | | |
| Shannara | PC | 1.0 | Rerelease | | 7-81055-33802-6 | |
| Shannara | PC | 1.0.0 | Original | | | |
| Shanghai: Great Moments | PC | 2.00 | Bundle Version Canon OEM | | | |
| Shanghai II: Dragon's Eye | PC | 1.05 | 2 for 1 | | CDD-3044-101-U3 | |
| Shanghai Double Pack | PC | | Original | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock's Fall '96 Demo CD | PC | | | | | |
| Shakii the Wolf | PC | | Original | | | |
| Shadows of Cairn | PC | 1.0.022 | Rerelease | | ROM-53337 | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shadowlands | PC | | Megapak 2 | | | |
| Shadowgrounds (Disc 2) | PC | 1.01 | Original | | 000046-CD2 | |
| Shadowgrounds (Disc 1) | PC | 1.01 | Original | | 000046-CD1 | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| Shadow Wolf Mysteries: Curse of the Full Moon / Bane of the Family | PC | | | | 33425010US | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadow Man | PC | | Original | | | |
| Shadow Man | PC | | Demo | | | |
| Shadow Force: Razor Unit | PC | | Special Forces Pack | | SFRU-0414 | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shadow Company: Left for Dead (Digital Press Kit) | PC | | Press Kit | | 5051895 | |
| Shadoan | PC | | Interactive Preview | | | |
| Shade: Wrath of Angels (Press Disc) | PC | | Press Kit | | | |
| Seven Kingdoms: The Fryhtan Wars / Shadow Company: Left for Dead | PC | | Demo | | 5051859 | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.0.4140.0 | Scholastic | | P/N DVD5107350 | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original | | | |
| The Settlers: Heritage of Kings | PC | 1.01.0163 | Original | | 682011-DVD | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers III: Quest of the Amazons | PC | | Original | | | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Reading Basics | PC | | Encore | | 10200 | |
| Sesame Street: Numbers | PC | | Original | | | |
| Sesame Street: My Baby & Me (Disc 2) (Sesame Street Greatest Hits Sampler) | PC | 1.0 | Original | | SSY744AE-CD2 | |
| Sesame Street: My Baby & Me (Disc 1) (Baby & Me) | PC | 1.0 | Original | | SSY744AE-CD1 | |
| Sesame Street: Letters | PC | | | | 9367A | |
| Sesame Street: Letters | PC | | Original | | | |
| Sesame Street: Let's Make a Word! | PC | | Bundle Version Creative Labs OEM | | 1713310119-1 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: First Steps | PC | | Original | | 05SSRTLXT-01 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 2) (Reading Adventure) | PC | | Original | | EPK-744AE-CD2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street: Elmo's Preschool (Disc 2) (Search & Learn Adventures) | PC | 3.1 | Original | | P/N 379663-CD2 | |
| Sesame Street: Elmo's Preschool (Disc 1) (Elmo's Preschool) | PC | 3.1 | Original | | P/N 379663-CD1 | |
| Sesame Street: Elmo's Preschool | PC | | | | 11040CD | |
| Sesame Street: Elmo's Art Workshop | PC | | Original | | EAW844AE-CD | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Create & Draw in Elmo's World | PC | | Original | | 24139-0919 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Art Workshop | PC | | Original | | 9369 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam Gold (Disc 2) | PC | 1.05 | Original | | | |
| Serious Sam Gold (Disc 1) | PC | 1.05 | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Rerelease | | CD-W58-1103-1 | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentient | PC | | Original | | | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Senha N. 1 | PC | | | | | |
| Sengoku Rance 戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Screenshots 2000 Sega E3 2000 | PC | | Press Kit | | | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Rally Championship Sega Racing: Sega Rally Championship | PC | | Demo | | 85051 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega Family Fun Pak | PC | | Original | | | |
| Sega Entertainment's Arcade Sampler | PC | | | | | |
| Sega E3 Press Kit 2005 2005 E3 Press Kit | PC | | Press Kit | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PC | 2.0 | Original | | | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PC | 2.0 | Original | | | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PC | 2.0 | Original | | | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PC | 2.0 | Original | | | |
| The Secret of Googol 2: Reshaping Googol: Castle / Ocean | PC | 2.0 | Original | | | |
| The Secret Island of Dr. Quandary | PC | 1.0 | SoftKey | | PDQ944AE-CD | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| SEC: Southeastern Conference Educational Software | PC | | Original | | | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search & Rescue 3 | PC | 1.0.0.0 | Original | | | |
| Seal of Evil | PC | | Original | | 904066DVD | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| The Scroll | PC | | | | | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
| Screamer | PC | | White Label | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | | |
| ScottForesman Wide World of Mathematics | PC | | Original | | 45678910 ET 030201009998 | |
| Score International Baja 1000: The Official Game | PC | | Original | | 35619./101.US | |
| Score 4 | PC | | Original | | | |
| Scorched Planet | PC | | Original | | | |
| Scorched Planet | PC | | Bundle Version Matrox OEM | | /MYST-CD/GA1/01 | |
| Scooter's Magic Castle / Eagle Eye Mysteries in London | PC | | Original | | 1213330151 | |
| Scooby-Doo! Phantom of the Knight | PC | 1.0 | Original | | 380325-CD | |
| Scooby-Doo! Mystery of the Fun Park Phantom | PC | | Original | | | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Scooby-Doo! Jinx at the Sphinx | PC | | Scholastic | | 380849-CD | |
| Scissors 'n' Stones | PC | | Original | | | |
| Science Fiction: The Ultimate Collection (Disc 1) | PC | | | | 11014 | |
| Science Blaster Jr. | PC | | Rerelease | | | |
| Science Blaster Jr. | PC | | Original | | | |
| Science Arcade | PC | | Original | | Part No.: MAR476 | |
| The Sci-Fi Collection | PC | | Original | | | |
| SCI Games E3 2005 Press Kit | PC | | Press Kit | | | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 2) (Learning Adventures) | PC | | Original | | SRT744AE-CD2 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744BE-CD1 | |
| Schoolhouse Rock! Thinking Games Deluxe (Disc 1) (Thinking Games) | PC | | Original | | SRT744AE-CD1 | |
| Schoolhouse Rock! Thinking Games | PC | | Original | | BBT844AE-CD | |
| Schoolhouse Rock! Math Rock | PC | 1.0 | Scholastic | | P/N CDR9835976 | |
| Schoolhouse Rock! Math Rock | PC | | Smart Saver | | SHR744AE-CD | |
| Schoolhouse Rock! Grammar Rock | PC | 1.0 | Scholastic | | P/N CDR9835984 | |
| Schoolhouse Rock! Grammar Rock | PC | | Original | | 9227 | |
| Schoolhouse Rock! Grammar Rock | PC | | SmartSaver | | SGR744AE-CD | |
| Schoolhouse Rock! America Rock | PC | | Original | | 21080CD | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade Essentials (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 2) (4th Grade) | PC | | Original | | SGD744AE-CD2 | |
| Schoolhouse Rock! 3rd & 4th Grade (Disc 1) (3rd Grade) | PC | | Original | | SGD744AE-CD1 | |
| Schoolhouse Rock! 1st & 2nd Grade Essentials (Disc 1) | PC | | Original | | 21330CD-1 | |
| School Zone Transition Math: Grades K-1 | PC | .5 | Original | | 08034 | |
| School Zone Phonics: Grades 2-3 | PC | v.5 | Original | | 08064 | |
| School Zone Math: Grade 2 | PC | v.5 | Original | | 08032 | |
| School Zone Math: First & Second Grade | PC | | Original | | 08020 | |
| School Zone Flash Action Software: Multiplication/Division | PC | | Original | | 08021 | |
| School Tycoon | PC | | Scholastic | | P/N: CDR 21661-1R | |
| School Tycoon | PC | | Original | | | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Scholastic's The Magic School Bus Lands on Mars: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0400 Part No. X05-64212 | |
| Scholastic's The Magic School Bus in Concert: Activity Center | PC | 1.0.0.2 | Original | | 0400 Part No. X05-64231 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0010 | Bundle Version OEM | | 0296 Disc Assy. 000-30505 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.0 | Original | | 0396 Part No. 90618, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original | | Disc Assy. 451-052-012 0396 Part No. 90626 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.0 | Original | | 0894 Part No. 59104, Disc Assy 299-052-002 | |