Region | Title | System | Version | Edition | Languages | Serial | Status |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Original | | GAG744AE-CD | |
| Super Lucky's Tale (Disc 2) | PC | | Original | | | |
| Super Lucky's Tale (Disc 1) | PC | | Original | | | |
| Super Games for Windows: Volume II | PC | | Original | | | |
| Super GameHouse Collection Super Collapse! / Super Glinx! / Super Nisqually | PC | | MacPlay | | | |
| Super Duper Arcade 2 | PC | | Original | | CS99ARC011, Part No. 04-17836CD | |
| Super Duper Arcade 1 | PC | | Original | | Part No. 04-17834CD | |
| Super Collapse! II | PC | 1.33 | Original | | | |
| Super City Create City | PC | 1.0 | Original, Covermount | | | |
| Summoner (Disc 2) | PC | 1.00 | Original | | | |
| Summoner (Disc 1) | PC | 1.00 | Original | | | |
| The Sum of All Fears | PC | 1.0.12.0 | Original | | 650362-CD | |
| Sudden Strike (Additional Missions) | PC | 1.0.0.1 | Original | | 04-22099CD2 | |
| Su-27 Flanker | PC | 1.0 | Original, Awesome 4 Pak | | | |
| Stuart Little: Big City Adventures Stuart Little: Big City Adventures CD-ROM Game | PC | | Original | | Product # 99716 | |
| Stuart Little Learning Adventures: His Adventures in Wordland (Disc 2) | PC | 1.0 | Original | | 381676-CD2 | |
| Stronghold Crusader FireFly Studios' Stronghold Crusader | PC | 1.1 | Rerelease | | | |
| Stronghold Crusader FireFly Studios' Stronghold Crusader | PC | 1.0 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.2 | Original, Maximum Strategy | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.1 | Original | | | |
| Stronghold FireFly Studios' Stronghold | PC | | Stronghold Warchest | | | |
| Strike Commander / Wing Commander: Privateer | PC | | Special CD-ROM Edition | | 1009121 | |
| Streets of SimCity | PC | 1.0 | Original | | 1040207 | |
| Streets of SimCity | PC | 1.0 | CD-ROM Classics, 10 Sims for $20 | | 1127517 | |
| Street Fighter IV | PC | 1.00.3013 | Original, Limited Edition | | | |
| Strategy Challenges Collection 1 | PC | 1.04 | Original, OEM Bundle | | 102771 | |
| Strange Cases: The Tarot Card Mystery / Strange Cases: The Lighthouse Mystery | PC | | The Best of Big Fish Games | | 33364101US | |
| Stories: The Path of Destinies (Installation Disc) | PC | 0.0.18092 | Collector's Edition, GameTrust Collection | | | |
| Stonekeep | PC | 1.0 | Interactive Preview | | CD-ICD-190-0 | |
| The Sting! | PC | v2.0e | Original | | ROTHESTING0004USLAB | |
| Still Life (Disc 2) (Play) | PC | 1.0 | Original | | PCO461CD | |
| Still Life (Disc 1) (Install) | PC | 1.0 | Original | | PCO461CD | |
| Stephen King's F13 Stephen King's F13: Ctrl,Alt, ...Shiver | PC | | Original | | | |
| Stellar Forces Stellar Forces Expansion Pak: Over 50 Add-On Levels for StarCraft | PC | 2.0 | Original | | | |
| Stellar 7 | PC | | | | 836034910 | |
| Steins;Gate | PC | System 1.20 / Script 1.11 | Limited Edition | | | |
| State of Decay: Year-One Survival Edition | PC | | Original | | | |
| Starsiege: Tribes | PC | 1.0 | Original | | | |
| Starship Titanic (Disc 1) Douglas Adams: Starship Titanic | PC | 1.00.42b | Rerelease | | | |
| StarLancer (Disc 2) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67023 | |
| StarLancer (Disc 1) Microsoft StarLancer | PC | 1.0 | Original, Microsoft Action Pack | | 0200 Part Number X05-67021 | |
| Stargunner | PC | 1.0 | Original | | P/N 7235 | |
| StarFlyers: Royal Jewel Rescue | PC | 1.0 | Original | | 381547A-CD | |
| StarFlyers Alien Space Chase | PC | 1.0 | Original | | 380853A-CD | |
| The Starfire Soccer Challenge | PC | | Original | | 109-10-2000 | |
| Stardew Valley | PC | 1.4.5 | Fangamer | | | |
| StarCraft: Brood War (Expansion Set) | PC | 1.15.2 | StarCraft Battle Chest | | | |
| StarCraft: Brood War (Expansion Set) | PC | 1.04 | Original | | S03995 | |
| StarCraft II: Wings of Liberty | PC | | Original | | | |
| StarCraft II: Wings of Liberty | PC | | Original, Collector's Edition | | | |
| StarCraft II: Legacy of the Void (Disc 2) | PC | | Original | | | |
| StarCraft II: Legacy of the Void (Disc 1) | PC | | Original | | | |
| StarCraft | PC | 1.15.2 | StarCraft Battle Chest | | | |
| StarCraft | PC | 1.05b | StarCraft Battle Chest | | S0437070 | |
| StarCraft | PC | 1.05 | StarCraft Battle Chest | | S7154921 | |
| StarCraft | PC | 1.0 | Original | | | |
| Star Wars: Yoda Stories / Star Wars: Behind the Magic: Vehicles Special Edition | PC | 1.0.0.1 | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061834 | |
| Star Wars: Yoda Stories | PC | 1.0 | Original | | 3111830 | |
| Star Wars: Yoda Stories | PC | 1.0 | Original | | 3111830 | |
| Star Wars: X-Wing: Collector's CD-ROM / Star Wars: X-Wing vs. TIE Fighter: Flight School | PC | | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061830 | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.0 | Collector Series | | 8051831 | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 2.0 | Bundle Version Diamond OEM | | 75000203-100 | |
| Star Wars: X-Wing vs. TIE Fighter (Multiplayer Disc) | PC | 1.00 | Original | | 2081831 | |
| Star Wars: X-Wing Alliance (Disc 2) | PC | 2.02a | Original | | 2091831, 2091831R1 | |
| Star Wars: X-Wing Alliance (Disc 1) | PC | 2.02a | Original | | 2091830, 2091830R1 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0A | Collector Series, Rerelease | | 2064130, 8051832 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | 1.0.0.1 | The LucasArts Archives Vol. IV: Star Wars Collection II | | 8061831 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | The LucasArts Archives Vol. II: Star Wars Collection | | 8031832 | |
| Star Wars: TIE Fighter: Collector's CD-ROM | PC | | Original | | 2061830 | |
| Star Wars: The Old Republic (Disc 3) | PC | 1.0.0.0 | Original | | 1957827 | |
| Star Wars: The Old Republic (Disc 2) | PC | 1.0.0.0 | Original | | 1957817 | |
| Star Wars: The Old Republic (Disc 1) | PC | 1.0.0.0 | Original | | 1957807 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 2) | PC | 0.0.0.0 | Original | | 12241-1DDA2 | |
| Star Wars: The Force Unleashed: Ultimate Sith Edition (Disc 1) | PC | 0.0.0.0 | Original | | 12241-1DDA | |
| Star Wars: Starfighter | PC | 1.0 | Original, Rerelease | | 6551830, 6551830R1 | |
| Star Wars: Shadows of the Empire: Battle of Hoth | PC | 1.0 | Bundle Version Diamond OEM | | 75000204-100 | |
| Star Wars: Shadows of the Empire | PC | 1.0 | Original | | 3121830 | |
| Star Wars: Screen Entertainment | PC | | Original, The LucasArts Archives Vol. I | | 633630 | |
| Star Wars: Rogue Squadron 3D | PC | 1.3 | Rerelease, CompUSA Exclusive | | 6521830R2 | |
| Star Wars: Rogue Squadron 3D | PC | 1.3 | Rerelease | | 6521830 | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, 636130 | |
| Star Wars: Rebel Assault: Special Edition | PC | | The LucasArts Archives Vol. I | | 636130 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | 1.0 | Original | | 3091831, CDRM1361640 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 2) | PC | | The LucasArts Archives Vol. II: Star Wars Collection | | 8031836 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PC | 1.0 | Original | | 3091830, CDRM1361630 | |
| Star Wars: Rebel Assault II: The Hidden Empire (Disc 1) | PC | | The LucasArts Archives Vol. II: Star Wars Collection | | 8031834 | |
| Star Wars: Rebel Assault II: Encounter on Dreighton | PC | WD1.09 | Star Wars Masterpieces, Bundle Version OEM | | 644030 | |
| Star Wars: Rebel Assault | PC | 1.72 | The LucasArts Archives Vol. II: Star Wars Collection | | 8031833 | |
| Star Wars: Rebel Assault | PC | 1.02 | Original | | 632630, CDRM1132180 | |
| Star Wars: Pit Droids | PC | | Original | | 3513030 | |
| Star Wars: Math: Jabba's Game Galaxy | PC | | Original, Scholastic | | P/N CDR5077850 | |
| Star Wars: Making Magic | PC | QA1.03 | Star Wars Masterpieces | | 8031835 | |
| Star Wars: Making Magic | PC | QA1.03 | Original, LucasArts Archives Vol. II, The: Star Wars Collection | | 8031835 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 4) | PC | 1.0 | Original | | 3261833, 3261833R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 3) | PC | 1.0 | Original | | 3261832, 3261832R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 2) | PC | 1.0 | Original | | 3261831, 3261831R | |
| Star Wars: Knights of the Old Republic II: The Sith Lords (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3261830 | |
| Star Wars: Knights of the Old Republic II: The Sith Lords | PC | 2.2.0.0 | Star Wars: Knights of the Old Republic Collection (DVD-ROM) | | 9982531 | |
| Star Wars: Knights of the Old Republic | PC | 1.3.1.0 | Star Wars: Knights of the Old Republic Collection (DVD-ROM) | | 9982530 | |
| Star Wars: Jedi Knight: Mysteries of the Sith Star Wars: Jedi Knight: Dark Forces II: Ambush at Altyr 5 | PC | 1.0 | Demo: Bundle Version OEM | | 647030, CD-C95-990-E | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Original | | 7101830 | |
| Star Wars: Jedi Knight: Mysteries of the Sith | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061833 | |
| Star Wars: Jedi Knight: Dark Forces II: Pathways to the Force | PC | | Bundle Version Diamond OEM | | 646230, 75000202-100, CD-C95-829-DIA | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 2) | PC | 1.0 | Original | | 9521831 | |
| Star Wars: Jedi Knight: Dark Forces II (Disc 1) | PC | 1.0 | Original | | 9521830 | |
| Star Wars: Jedi Knight: Dark Forces II | PC | 1.0 | Demo (LucasArts Archives Vol. IV, The: Star Wars Collection II) | | 8061832 | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.02a | Original | | 9541830 | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.02a | Rerelease, CompUSA Exclusive | | 9541830R2, 9541830R3 | |
| Star Wars: Jar Jar's Journey Adventure Book | PC | 1.0 | Original | | #3520530 | |
| Star Wars: Galactic Battlegrounds: Clone Campaigns | PC | 1.0 | Original | | 7111830 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 2) | PC | | Rerelease | | 8531031R, 8531031R1 | |
| Star Wars: Galactic Battlegrounds Saga (Disc 1) | PC | | Rerelease | | 8531030R, 8531030R1 | |
| Star Wars: Galactic Battlegrounds (Disc 2) (Play) | PC | 1.0 | Original | | 8531831, 8531831R1 | |
| Star Wars: Galactic Battlegrounds (Disc 1) (Install) | PC | 1.0 | Original | | 8531830, 8531830R1 | |
| Star Wars: Episode I: The Gungan Frontier | PC | 1.0 | Original | | #3512030 | |
| Star Wars: Episode I: Insider's Guide (Disc 2) | PC | 1.0 | Original | | 3161831 | |
| Star Wars: Episode I: Insider's Guide (Disc 1) | PC | 1.0 | Original | | 3161830 | |
| Star Wars: Empire at War: Gold Pack | PC | 1.05.48824 | Original | | 9999830 | |
| Star Wars: Empire at War: Forces of Corruption (Disc 2) | PC | 1.00.55911 | Original | | 7131831 | |
| Star Wars: Empire at War: Forces of Corruption (Disc 1) | PC | 1.00.55911 | Original | | 7131830 | |
| Star Wars: Empire at War (Disc 2) | PC | 1.00.36493 | Rerelease | | 8541831R | |
| Star Wars: Empire at War (Disc 2) | PC | 1.00.36493 | Original, Collector's Edition | | 8541831 | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Rerelease | | 8541830R | |
| Star Wars: Empire at War (Disc 1) | PC | 1.00.36493 | Original, Collector's Edition | | 8541830 | |
| Star Wars: Empire at War | PC | 1.00.35517 | Demo | | 8330730 | |
| Star Wars: DroidWorks | PC | 1.0 | Original | | | |
| Star Wars: Dark Forces | PC | 1.0L Build 1 | Super Sampler Edition: LucasArts Archives Vol. II, The: Star Wars Collection | | 8031831 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Original | | 635930 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Rerelease, The LucasArts Archives Vol. III | | 8041834 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Rerelease, LucasArts Archives Vol. IV, The: Star Wars Collection II | | 3064130, 8061835 | |
| Star Wars: Dark Forces | PC | 1.0 Build 1 | Original | | 633830 | |
| Star Wars: Battlefront II (Disc 4) | PC | 1.0 | Original | | 3281833 | |
| Star Wars: Battlefront II (Disc 3) | PC | 1.0 | Original | | 3281832 | |
| Star Wars: Battlefront II (Disc 2) | PC | 1.0 | Original | | 3281831 | |
| Star Wars: Battlefront II (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3281830 | |
| Star Wars: Battlefront II | PC | 1.1 | Star Wars: Fan Favorites I (DVD-ROM) | | 9982131 V1.1.0.1 | |
| Star Wars: Battlefront (Disc 3) | PC | 1.0 | Original | | 3241832 | |
| Star Wars: Battlefront (Disc 2) | PC | 1.0 | Original | | 3241831 | |
| Star Wars: Battlefront (Disc 1) (Play Disc) | PC | 1.0 | Original | | 3241830 | |
| Star Wars: Battlefront | PC | 1.2 | Star Wars: Fan Favorites I | | 9982130 V1.01.0.1 | |
| Star Wars: Battle for Naboo | PC | 1.0 | Original | | 6561830, 6561830R1 | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | 1.00 | Collector's Edition | | 3181832 | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | 1.00 | Collector's Edition | | 3181831 | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | 1.00 | Collector's Edition | | 3181830 | |
| Star Trek: Voyager: Elite Force: Expansion Pack | PC | 1.20 | Original | | 31151.101.US | |
| Star Trek: Voyager: Elite Force | PC | 1.10 | Star Trek: Action Pack | | 32257.101.US | |
| Star Trek: Voyager: Elite Force | PC | 1.10 | Rerelease | | 1000912.101.US, 32097.101.US | |
| Star Trek: Voyager: Elite Force | PC | 0.28 | Original, Collector's Edition | | 1000912.101.US | |
| Star Trek: Starship Creator | PC | | Original, Deluxe | | 31509-9 | |
| Star Trek: Starship Creator (Add-On Pack) | PC | | Deluxe | | 0-671-31758-X | |
| Star Trek: Starfleet Command: Orion Pirates | PC | 2.5.0.0 | Original | | CD-C95-1290-0 | |
| Star Trek: Starfleet Command II: Empires at War (Disc 2) | PC | 1.0.0.2 | Original | | CD-C95-1185-1 | |
| Star Trek: Starfleet Command II: Empires at War (Disc 1) | PC | 1.0.0.2 | Original | | CD-C95-1185-0 | |
| Star Trek: Starfleet Command | PC | 1.02.01 | Gold Edition | | CD-W58-1177-0 | |
| Star Trek: Starfleet Academy: Strategic Command (Disc 2) | PC | 1.0 | Original | | CD-C95-1044-1 | |
| Star Trek: Starfleet Academy: Strategic Command (Disc 1) | PC | 1.0 | Original | | CD-C95-1044-0 | |
| Star Trek: Starfleet Academy: Cadet Briefing | PC | 0.99 | Star Trek: Federation Compilation | | CD-C95-893-0 | |
| Star Trek: Starfleet Academy (Disc 5) | PC | 0.99, 1.1 | Original | | CD-H95-069-4, CD-MCR-069-4 | |
| Star Trek: Starfleet Academy (Disc 4) | PC | 0.99, 1.1 | Original | | CD-H95-069-3, CD-MCR-069-3 | |
| Star Trek: Starfleet Academy (Disc 3) | PC | 0.99, 1.1 | Original | | CD-H95-069-2, CD-MCR-069-2 | |
| Star Trek: Starfleet Academy (Disc 2) | PC | 0.99, 1.1 | Original | | CD-H95-069-1, CD-MCR-069-1 | |
| Star Trek: Starfleet Academy (Disc 1) | PC | 0.99 | Original | | CD-H95-069-0 | |
| Star Trek: Legacy | PC | 1.0 | Original | | | |
| Star Trek: Klingon Academy | PC | 1.0 | Interactive Demo | | CD-C95-856-D1 | |
| Star Trek: Klingon (Disc 2) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon (Disc 1) (Installation) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Judgment Rites | PC | | Star Trek: Federation Compilation | | CD-C95-893-1 | |
| Star Trek: Judgment Rites | PC | | Original, Limited CD-ROM Collector's Edition | | CD-ICD-200-0, CD-ICD-728-2 | |
| Star Trek: Judgment Rites (Collector's Disc) | PC | | Limited CD-ROM Collector's Edition | | CD-ICD-200-1 | |
| Star Trek: Deep Space Nine: The Fallen | PC | 1.0 | Original | | 0-671-57663-1, S5293110 | |
| Star Trek: Bridge Commander | PC | 1.0 | Original | | 31127.101.US | |
| Star Trek: Away Team | PC | 1.00 | Original | | 30025.101.US | |
| Star Trek: Armada | PC | 1.2 | Rerelease, Star Trek: Action Pack | | 1000913.101.US, 32257.102.US | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | Star Trek: Federation Compilation | | CD-C95-893-2 | |
| Star Trek Pinball | PC | 1.10 | Rerelease | | CD-C95-675-2 | |
| Star Trek Omnipedia | PC | | Original | | | |
| Star Crusader | PC | | Original | | | |
| Star Control 3 | PC | | Original | | Part #:5000-00419 | |
| Star Command Revolution | PC | 1.0 | Original | | 04-12257CD | |
| Square Enix: Final Fantasy VII Advent Children Trailer | PC | | Press Kit | | | |
| Square Enix E3 2005 Media CD | PC | | Press Kit | | | |
| Spy Masters: Training Mission / JumpStart Music | PC | | Great Clips | | W0000946 | |
| Spy Kids: Mega Mission Zone | PC | 3.6.27 | Original | | H3343 | |
| Spy Kids 3-D: Game Over | PC | | Original | | I6100 | |
| Spy Fox: "Operation Ozone" | PC | | Original | | Part No. 04-22394CD | |
| Spy Fox in "Hold the Mustard" | PC | 1.0 | Original | | Part No. 04-17574CD | |
| Spy Fox in "Dry Cereal" | PC | 2.00 | Original | | Part #04-00000H1407 | |
| Spy Fox in "Dry Cereal" | PC | 1.0 | Original | | 04-70281, Part # 0001407, Part No. 04-00000H1529 | |
| Spy Fox in "Cheese Chase" | PC | 2.00 | Rerelease | | Part No. 04-15244CD | |
| Spy Fox 2: "Some Assembly Required" | PC | 1.0.0.1 | Original | | Part No. 04-17571CD | |
| Sports Illustrated Kids: Soccer | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Basketball | PC | | Wendy's Kids' Meal | | | |
| Sporting Clays: Interactive Shooting Simulation | PC | 1.0 | Original | | P/N 7407 | |
| Spore: Galactic Adventures | PC | 1.0 | Original | | 1535407 | |
| Spore: Creepy & Cute Parts Pack | PC | | Original | | 1907607 | |
| Spore: Creature Creator | PC | | Original | | 1586407 | |
| Spore | PC | 1.00.000 | Original | | 1535207 | |
| Spore | PC | 1.0 | Galactic Edition | | 1908007 | |
| Spore | PC | | Original | | 1535207 | |
| Spintires Spintires: Offroad Truck Simulator | PC | | Original | | | |
| Spider-Man: Web of Shadows | PC | 1.0 | Original | | 33211.101.EF, 33211.101.US | |
| Spider-Man | PC | | Original | | 31131.101.US | |
| SpellForce: The Order of Dawn (Disc 2) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD2 v1.0 E, 28017-SM2 v1.0 F | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
| Spell It Deluxe | PC | | Original | | | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 Rev.1 | |
| Spec Ops: Ranger Gold | PC | 1.0 | Original, Platinum Collection | | CD-RG-004 | |
| Spec Ops: Ranger Assault | PC | | Covermount | | CDE30_CDA | |
| Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| Spaceship Warlock | PC | 1.1.3 "MPC" | Ultimate Game Collection | | | |
| Spacebound Space Bound | PC | | Original | | | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Space Siege | PC | 1.0 | Original | | | |
| Space Quest: Collection Series (Disc 2) | PC | | Original | | | |
| Space Quest: Collection Series (Disc 1) | PC | | Original | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | Original | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.0 | Original | | S329430 | |
| Space Invaders | PC | 1.0 | Original | | 1000916.101.US | |
| Space Invaders | PC | | Covermount | | | |
| Space Colony | PC | | Interactive Demo | | | |
| South Park | PC | | Original | | | |
| Soulbringer (Disc 2) | PC | 1.0.0.1 | Original, Dual Jewel | | CD-C95-1077-1, CD-C95-1306-4 | |
| Soulbringer (Disc 1) | PC | 1.0.0.1 | Dual Jewel, Rerelease | | CD-C95-1306-3 | |
| Sorry! | PC | 1.3 | Original | | 99040 | |
| Sonny's Race for Chocolatey Taste | PC | | General Mills | | A38341 | |
| Sonic's Schoolhouse | PC | 1.1 | Expert Software | | 6806 02 | |
| Sonic's Schoolhouse | PC | 1.0 | Original | | 85047 | |
| Sonic Riders (Disc 3) | PC | 1.0 | Original, Scholastic | | P/N CDR5047633 | |
| Sonic Riders (Disc 2) | PC | 1.0 | Original, Scholastic | | P/N CDR5047633 | |
| Sonic R | PC | | Expert Software | | 682501.101.US | |
| Sonic CD | PC | 1.01 | Bundle Version OEM | | P/N 647107-001 | |
| Sonic CD | PC | 1.01 | Bundle Version Packard Bell OEM | | 170882, P/N 647107-002 | |
| Sonic CD | PC | 1.0 | Bundle Version OEM | | P/N 647107-001 | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.0.0.9 | Original | | 35033.102.US | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.0.0.9 | Original | | 35033.101.US | |
| Sonic & Knuckles Collection | PC | 1.0 | Expert Software, Sonic Action 4 Pack | | 6820 01, T-6820-02 | |
| Sonic & Knuckles Collection | PC | | Original, Jack in the Box | | 85037 | |
| Solitaire Master 2 | PC | 2.1 | Original | | 02-6306-10 | |
| Soldier of Fortune II: Double Helix (Disc 1) | PC | | Original | | 31147.101.US | |
| Soldier of Fortune | PC | 1.07f | Platinum Edition (Rerelease) | | 31761.101.US | |
| Soldier of Fortune | PC | 1.06 | Gold Edition | | 30173.101.US | |
| Soldier of Fortune | PC | 1.04 | Linux | | | |
| Soldier of Fortune | PC | 1.03 | Original | | 1000910.101.US | |
| The Software Toolworks CD Deluxe Pack 4 | PC | | Bundle Version OEM | | 2192610-590001/1034100, CDRM1170920 | |
| Software JukeBox: Home & Entertainment Edition: Vol. 1 No. 1 | PC | | Original | | CDRM1006830 | |
| SODA Off-Road Racing | PC | | All American Sports Series | | | |
| Snowmobile Racing | PC | | Original | | 04-17527CD | |
| Snapshot Adventures: Secret of Bird Island | PC | | Original | | P/N 61191-CD | |
| Smashing Reversi Reversi | PC | | Pocketware | | #11 | |
| Smart Games Puzzle Challenge 3 | PC | 1.0 | Original | | 99254 | |
| Slingo | PC | 1.00 | Original | | 99310 | |
| Slam Tilt Pinball | PC | 1.0 | Expert Software | | 8694 01 | |
| Sins of a Solar Empire | PC | 1.00 | Original | | | |
| SiN Episodes: Emergence | PC | | Original | | 984707 | |
| SiN | PC | 1.00 | Original | | 1000076.101.US | |
| SimTunes | PC | 1.2nre | Kids Classics | | 1128707 | |
| SimTown | PC | 1.00 | Rerelease | | 1126107 | |
| SimTown | PC | 1.0 | Original | | 0037-000-0601-B | |
| SimTower SimTower: The Vertical Empire | PC | 1.0 | Original | | 0051-040-0601-A | |
| SimTheme Park Sim Theme Park | PC | | Gold Edition, Scholastic | | 1403357 | |
| SimTheme Park Sim Theme Park | PC | | Sim Mania 2, The Kids Collection | | 1229827, 1641517 | |
| SimTheme Park Sim Theme Park | PC | | Gold Edition | | 1403337 | |
| SimTheme Park (Bonus Rides and Attractions) Sim Theme Park | PC | | Gold Edition, Sim Mania 2 | | 1229817, 1403347, 1641527 | |
| The Sims: Vacation (Expansion Pack) | PC | | Original | | 1448807 | |
| The Sims: Vacation (Expansion Pack) | PC | | Expansion Collection Volume Three | | 1448807 | |
| The Sims: Unleashed (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459517 | |
| The Sims: Unleashed (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume One | | 1459507 | |
| The Sims: Superstar (Expansion Pack) (Disc 2) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462617 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | 1.0 | Original, Expansion Collection Volume Three | | 1462607 | |
| The Sims: Superstar (Expansion Pack) (Disc 1) | PC | | | | 1462607 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Expansion Collection Volume Two | | 1472017 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 2) | PC | | Original | | 1472017 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | 1.0 | Original | | 1472007 | |
| The Sims: Makin' Magic (Expansion Pack) (Disc 1) | PC | | Expansion Collection Volume Two | | 1472007 | |
| The Sims: Livin' Large (Expansion Pack) | PC | 1.0 | Original | | 1422707 | |
| The Sims: House Party (Expansion Pack) | PC | 1.0 | Original | | 1431307, 1431317 | |
| The Sims: House Party (Expansion Pack) | PC | | Double Deluxe, Expansion Collection Volume One, Mega Deluxe | | 1446107 | |
| The Sims: Hot Date (Expansion Pack) | PC | 1.1 | Original, Expansion Collection Volume Two, Mega Deluxe | | 1439827 | |
| The Sims: Double Deluxe (Bonus CD) | PC | | Double Deluxe, Mega Deluxe | | 1474107 | |
| The Sims: Deluxe Edition (Disc 2) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457657 | |
| The Sims: Deluxe Edition (Disc 1) | PC | 1.0 | Original, Double Deluxe, Mega Deluxe | | 1457647 | |
| The Sims | PC | 1.0 | Original | | 1500807 | |
| The Sims | PC | 1.0 | Original | | 1500827 | |
| The Sims | PC | | Bundle Version Gateway OEM | | 1500827 | |
| The Sims Online (Disc 2) | PC | 1.0 | Original | | 1436717 | |
| The Sims Online (Disc 1) | PC | 1.0 | Original | | 1436707 | |
| The Sims Medieval: Pirates & Nobles | PC | 2.0.109.00001 | Original | | 1962507 | |
| The Sims Medieval | PC | 1.0.286.00001 | Limited Edition | | 1945407 | |
| The Sims Life Stories | PC | 1.0.22.17622 | Original | | 1528207 | |
| The Sims Carnival: SnapCity | PC | 0.029 | SimCity Box | | 1907347 | |
| The Sims 4: Island Living | PC | | Original, Rerelease | | 3765703401, 3765703402 | |
| The Sims 4 (Disc 2) | PC | 1.0 | Limited Edition | | 7303703302, 7303703401 | |
| The Sims 4 (Disc 1) | PC | 1.0 | Limited Edition | | 7303703301, 7303703303 | |
| The Sims 3: World Adventures (Expansion Pack) | PC | 0.2.0.56 | Original, The Sims 3 Expansion Bundle | | 1539307 | |
| The Sims 3: Town Life Stuff | PC | | Original | | 1957907 | |
| The Sims 3: Seasons (Expansion Pack) | PC | | Original, Limited Edition | | 1978303301 | |
| The Sims 3: Pets (Expansion Pack) | PC | | Original, Limited Edition | | 1962207 | |
| The Sims 3: Monte Vista | PC | | Original, The Sims 3: Worlds Bundle | | 7299103401 | |
| The Sims 3: Late Night (Expansion Pack) | PC | 0.2.0.125 | Original, The Sims 3 Starter Pack | | 1915003301 | |
| The Sims 3: Island Paradise (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7301203301 | |
| The Sims 3: Into the Future (Expansion Pack) | PC | 1.0.0.1 | Original, Limited Edition | | 7308903401 | |
| The Sims 3: High-End Loft Stuff | PC | 0.2.0.84 | The Sims 10th Anniversary | | 1941507 | |
| The Sims 3: Hidden Springs | PC | | Original, The Sims 3: Worlds Bundle | | 1979707 | |
| The Sims 3: Generations (Expansion Pack) | PC | 1.0.0.1 | Original, The Sims 3 Expansion Bundle | | 1957307 | |
| The Sims 3: Dragon Valley | PC | | Original | | 7312803402 | |
| The Sims 3 | PC | 1.42.130.019037 | The Sims 3 Starter Pack | | 1539003301 | |
| The Sims 3 | PC | 1.0.631.00001, 0.0.0.11195 | Original, The Sims 3: Deluxe | | 1539007 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.286 | Rerelease | | 1491737 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.286 | Rerelease | | 1491727 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| The Sims 2: Teen Style Stuff | PC | 1.11.0.44 | Original | | 1537007 | |
| The Sims 2: Sneak Preview CD | PC | | Original | | 1472027 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 2) | PC | 1.7.0.145 | Original, Slim Case | | 1562117 | |
| The Sims 2: Seasons (Expansion Pack) (Disc 1) | PC | 1.7.0.145 | Original, Slim Case | | 1562107 | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | Original | | 1526317 | |
| The Sims 2: Pets (Expansion Pack) (Disc 2) | PC | 1.6.0.259 | | | 1526317 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Pets (Expansion Pack) (Disc 1) | PC | 1.6.0.259 | Original | | 1526307 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Open for Business (Expansion Pack) | PC | 1.3.0.249 | Original | | 1515707 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.377 | Rerelease | | 1497037 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 2) | PC | 1.2.0.312 | Original | | 1497017 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.377 | Rerelease | | 1497027 | |
| The Sims 2: Nightlife (Expansion Pack) (Disc 1) | PC | 1.2.0.312 | Original | | 1497007 | |
| The Sims 2: Mansion & Garden Stuff | PC | 1.17.0.66 | Original | | 1918007 | |
| The Sims 2: IKEA Home Stuff | PC | 1.15.0.62 | Original | | 1578207 | |
| The Sims 2: H&M Fashion Stuff | PC | | Original | | 1536607 | |
| The Sims 2: Glamour Life Stuff | PC | 1.5.0.121 | Original | | 1520807 | |
| The Sims 2: Fun with Pets Collection | PC | 2.1 | Original | | 1685607 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 2) | PC | 1.13.0.135 | Original, Slim Case | | 1537117 | |
| The Sims 2: FreeTime (Expansion Pack) (Disc 1) | PC | 1.13.0.135 | Original, Slim Case | | 1537107 | |
| The Sims 2: Family Fun Stuff | PC | | Original | | 1515807 | |
| The Sims 2: Double Deluxe | PC | | Original | | 1597007 | |
| The Sims 2: Double Deluxe (Bonus DVD) | PC | | Original | | 1597027 | |
| The Sims 2: Deluxe | PC | 1.0.0.1068 | | | 1672927 | |
| The Sims 2: Deluxe (Bonus DVD) | PC | | Original | | 1672917 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 2) | PC | 1.10.0.111 | Original, Slim Case | | 1536717 | |
| The Sims 2: Bon Voyage (Expansion Pack) (Disc 1) | PC | 1.10.0.111 | Original, Slim Case | | 1536707 | |
| The Sims 2: Best of Business Collection | PC | 2.0 | Original | | 1685507 | |
| The Sims 2: Apartment Life (Expansion Pack) | PC | 1.16.0.179 | Original, Slim Case | | 1907807 | |
| The Sims 2 (Disc 4) | PC | 1.0.0.1022 | Rerelease | | 1472616, 1472656, 1472696, 1527637 | |
| The Sims 2 (Disc 3) | PC | 1.0.0.1022 | Rerelease | | 1472606, 1472646, 1472686, 1527627 | |
| The Sims 2 (Disc 2) | PC | 1.0.0.1022 | Rerelease | | 1472636, 1472676, 1472697, 1527617 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.932 | Original | | 1472607, 1472610 | |
| The Sims 2 (Disc 1) | PC | 1.0.0.1022 | Rerelease | | 1472626, 1472666, 1472687 | |
| The Sims 2 (Game Disk) | PC | 1.0.0.932 | Special DVD Edition | | 1488307 | |
| The Sims 2 (Bonus Disk) | PC | | Special DVD Edition | | 1488317 | |
| The Simpsons: Hit & Run (Disc 3) | PC | 1.0 | Original | | S7213230 | |
| The Simpsons: Hit & Run (Disc 2) | PC | 1.0 | Original | | S7213220 | |
| The Simpsons: Hit & Run (Disc 1) | PC | 1.0 | Original | | S7213210 | |
| SimPark | PC | 1.1 | Rerelease, Scholastic | | 1126207, 5710372C SP1 | |
| SimLife SimLife: The Genetic Playground | PC | | Scholastic | | 1111707, 7845126C SP1 | |
| SimLife SimLife: The Genetic Playground | PC | | Scholastic Clubs and Fairs | | 1111707, P1 | |
| SimIsle: Missions in the Rainforest | PC | 1.034 | CD-ROM Classics, 10 Sims for $20 | | 1102017 | |
| SimFarm SimFarm: SimCity's Country Cousin | PC | | Rerelease, 10 Sims for $20 | | 11116, 1162207 | |
| SimFarm SimFarm: SimCity's Country Cousin | PC | | Original, Maxis Collector's Series | | 0003-000-0612-A | |
| SimEarth | PC | | Scholastic | | 5675434C, DP19 | |
| SimEarth | PC | | Dual Jewel, 10 Sims for $20 | | 1111507 | |
| SimCopter SimCopter: Fly Missions in the Metropolis | PC | 1.02 | CD-ROM Classics, 10 Sims for $20 | | 1119307, 1119317, 1641567 | |
| SimCopter SimCopter: Fly Missions in the Metropolis | PC | 1.01 | Original | | 0077-000-0601-B | |
| SimCoaster | PC | | Sim Mania 2, The Kids Collection, Rerelease | | 1242617, 1246307 | |
| SimCity Societies Destinations | PC | 1.0 | SimCity Box | | 1907307 | |
| SimCity Societies | PC | 1.0 | Original | | 1574507 | |
| SimCity Classic | PC | 2.0 | Deluxe Edition | | 0002-000-0601B | |
| SimCity Classic | PC | 1.1 (Windows), 1.4 (Mac) | Scholastic | | 0002-000-0612-A | |
| SimCity Classic | PC | | CD-ROM Classics, 10 Sims for $20, Sim Mania Pack | | 1162907 | |
| SimCity 4 Deluxe Edition (Disc 1) | PC | 1.1.610.0 | SimCity Box | | 1907317 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Scholastic | | 1500907 | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| SimCity 3000 Unlimited | PC | | Rerelease | | 1446307, 1641507 | |
| SimCity 3000 | PC | 1.0.557.0 | Rerelease | | 1230007, 1500127 | |
| SimCity 2000: CD Collection | PC | 1.00 | Windows 95 | | 0026-000-0601-A | |
| SimCity 2000 Special Edition | PC | | CD-ROM Classics, Scholastic | | 10365, 1131107, 5710243CSP1, DP10 | |
| SimCity 2000 Special Edition | PC | | Original | | 0126-000-0601-A | |
| SimCity 2000 | PC | 1.2 | Bundle Version Diamond OEM | | 0059-031-0601-A | |
| SimCity 2000 SimCity 2000: The Ultimate City Simulator | PC | | Bundle Version Creative Labs OEM | | | |
| SimCity | PC | 1.0 | Original, Limited Edition | | 1971403401 | |
| SimAnt | PC | 2.0 | Classics, Maxis Collector's Series | | 0014-000-0612-A | |
| Silverload | PC | | | | | |
| Silent Thunder: A-10 Tank Killer II | PC | 1.01 | Rerelease | | | |
| Silent Steel | PC | 1.24.18.121 | Bundle Version Packard Bell OEM: Demo | | 170308 | |
| Silent Hunter III | PC | 1.4 | Encore | | | |
| Silent Hunter | PC | 1.0.324 | Original | | | |
| Sierra Pro Pilot 98 | PC | 1.0 | Original | | | |
| Sid Meier's SimGolf | PC | 1.01 | Rerelease | | 1434917 | |
| Sid Meier's SimGolf | PC | 1.0 | Sim Mania 2 | | 1277387 | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | 1015007 | |
| Sid Meier's Gettysburg! | PC | | CD-ROM Classics | | 1187707 | |
| Sid Meier's Civilization V: Gold Edition | PC | | Original | | 41252-1 | |
| Sid Meier's Civilization V | PC | | Original, Special Edition | | 31817-1 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Beyond the Sword (Disc 2) | PC | 3.0.3.1 (77541) | Rerelease | | 31173-1.2 | |
| Sid Meier's Civilization IV: Beyond the Sword (Disc 1) | PC | 3.0.3.1 (77541) | Rerelease | | 31173-1.1 | |
| Sid Meier's Civilization IV (Disc 2) | PC | 1.61 | Game of the Year Edition | | 77875-1.2REA | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 2) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.7 | |
| Sid Meier's Civilization IV (Disc 1) | PC | 1.61 | Game of the Year Edition | | 77875-1.1REA | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 1) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.6 | |
| Sid Meier's Civilization IV (Disc 3 & Manual) | PC | 1.61 | Game of the Year Edition | | 21712-1.3D | |
| Sid Meier's Civilization III: Conquests | PC | 1.0 | Original, Scholastic | | CDR9704405 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.3 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition | | Part # 24356CD1 | |
| Sid Meier's Civilization III | PC | 1.07f | Small Box Release | | BIPCIV3CDRV1 | |
| Sid Meier's Civilization III (Bonus CD) | PC | | Game of the Year Edition | | Part # 24356CD2 | |
| Sid Meier's Civilization II: Fantastic Worlds | PC | | Original | | 0-529-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Hasbro Rerelease | | Product # 99227 | |
| Sid Meier's Civilization II | PC | 1.0 | Original | | 0-492-47-101 | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | 105907 | |
| Shrak Shrak for Quake | PC | 1.0 | Original | | | |
| Shopmania | PC | | Original | | P/N 61227-CD | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | 1.00 | Original | | 1430717 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| Shogun: Total War (Disc 2) | PC | | Original | | 798717, 1224617 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | 798707 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Dual Jewel | | CD-C95-1298-0 | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original, Rerelease | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Rerelease | | | |
| Shivers | PC | 1.02 | Rerelease | | | |
| Shivers | PC | 1.02 | Original | | | |
| Shift 2: Unleashed | PC | | Limited Edition | | 1948307 | |
| Sherlock Holmes: The Awakened | PC | 3.0 | Original | | Art. Number PF0903/US2 | |
| Sherlock Holmes: Consulting Detective: Vol. I Sherlock Holmes: Consulting Detective: Vol. 1 | PC | | 5 ft. 10 PAK Vol. 2 | | | |
| Sherlock Holmes Chronicles | PC | 1.0 | Original | | DVD732CD | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Collector's Edition | | 33369101US | |
| Shattered Suns | PC | 1.0 | Original | | Part # CCS00003-1 | |
| SharkPort: Code and Save Transfer Kit | PC | 1.10 | Original | | | |
| SharkPort: Code and Save Transfer Kit | PC | 1.04 | Original | | | |
| Shannara | PC | 1.0 | Original | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shamrock Spring '97 Shamrock Spring '97 Demo Disk | PC | | | | | |
| Shadowrun Chronicles: Boston Lockdown | PC | 12.0.10093 | Cosmi | | DVDC6251 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| ShadowCaster | PC | | CD-ROM Classics, Electronic Arts Presents | | 5393 | |
| Shadow Watch | PC | 1.0 | Original | | | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Special Edition | | 04-12884CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-1 | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-0 | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Sesame Street: Let's Make a Word! | PC | | Original, Software for the fun of it | | KES006 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street Toddler: Elmo's Art Workshop (Disc 2) | PC | 3.0 | Rerelease | | STL744AE-CD2 | |
| Serious Sam: The First Encounter | PC | 1.02 | Bundle Version Gainward OEM | | | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.02 | Dual Jewel | | CD-C95-1298-1 | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Original | | CD-W58-1103-0 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Seek & Find Adventures | PC | | Original | | | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Sci-Fi Pinball | PC | | Original | | | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Sanity: Aiken's Artifact | PC | 1.0 | Original, Best Buy | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sam & Max: The Devil's Playhouse Sam & Max: Season Three | PC | 2.0.0.0 | Original | | | |
| Sam & Max: Season Two | PC | 1.5.0.0 | Original | | | |
| Sam & Max: Season One | PC | 1.0 | Original | | | |
| Sacred (Disc 2) | PC | 1.2.0.10 | Original | | 28302-CD2 v1.0 | |
| Sacred (Disc 1) | PC | 1.2.0.10 | Original | | 28302-CD1 v1.0 | |