Region | Title | System | Version | Edition | Languages | Serial | Status |
| Indiana Jones and the Fate of Atlantis | PC | | The LucasArts Archives Vol. I, The LucasArts Archives: Adventure Collection | | 632329 | |
| Indivisible | PC | | Collector's Edition | | | |
| Industry Giant | PC | | Original | | | |
| IndyCar Racing | PC | 1.05 | SierraOriginals | | | |
| IndyCar Racing II | PC | 1.0.1 | Original | | | |
| Infogrames Action Sampler: October 1999 | PC | | | | | |
| Infogrames Holiday 2001 Lineup (Press Disc) | PC | | Press Disc | | | |
| Inherent Evil: The Haunted Hotel | PC | | Original | | 21195.101.US | |
| Inherit the Earth: Quest for the Orb | PC | | Worlds of Sword & Steel | | 2216010-590002 | |
| Initiation: The Sacred Monuments of Giza and the Chambers of the Deep | PC | 1.1 | Original | | AFFS-CD 39243 | |
| Inner Worlds | PC | | | | | |
| Insaniquarium! Deluxe | PC | 1.0 | Original | | | |
| Insaniquarium! Deluxe | PC | 1.1 | Rerelease | | | |
| Insaniquarium! Deluxe | PC | 1.1 | Rerelease | | | |
| Inside Stories: Goldilocks and the Three Bears | PC | 5.0.0.134 | Original | | | |
| Inspector Parker Mystery Bundle | PC | 1.0.2.2624 | Original | | 1030-10292 | |
| Instant Immersion French: Levels 1, 2 & 3 (Software) | PC | 1.1.16 | Family Edition | | 21882-00 | |
| Instant Immersion Latin American Spanish: Levels 1, 2 & 3 (Software) | PC | 1.1.16 | Original | | 21880-00 | |
| Insurrection: Campaigns for StarCraft | PC | | Original | | | |
| Interactive Entertainment Episode 6 Special Edition | PC | | | | 802.767.9144 | |
| The Interactive Haggadah הגדה אינטראקטיבית של פסח | PC | | Original | | | |
| Interactive Math Journey | PC | 1.11 | SoftKey | | IMJ744CE-CD | |
| Interactive Storytime: Goldilocks & the Three Bears (Disc 1) | PC | | Original | | 82-0308-00 | |
| Interactive Storytime: The Boy & the Donkey (Disc 3) | PC | | Original | | 82-0310-00 | |
| Interactive Storytime: The City Mouse & the Country Mouse (Disc 5) | PC | | Original | | 82-0313-00 | |
| Interactive Storytime: The Lion & the Mouse (Disc 6) | PC | | Original | | 82-0311-00 | |
| Interactive Storytime: The Little Red Hen (Disc 2) | PC | | Original | | 82-0309-00 | |
| Interactive Storytime: The Tortoise & the Hare (Disc 4) | PC | | Original | | 82-0312-00 | |
| Intergalatic Exterminator | PC | 1.0 | Original | | 11-5807-10 IEXB | |
| International Rally Championship | PC | | Dual Jewel | | | |
| Internet Coach for Net Safety | PC | 1.2 | Original | | | |
| Interplay All-Nighter: Anthology No. 2 (Disc 1) Cyberia / SimCity Enhanced CD-ROM / Bonus Sampler | PC | | Original | | CD-ICD-355-1 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 2) Frankenstein: Through the Eyes of the Monster / Blackthorne / Bonus Sampler | PC | | Original | | CD-ICD-355-2 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 3) Castles II: Siege & Conquest | PC | | Original | | CD-ICD-355-3 | |
| Interplay All-Nighter: Anthology No. 2 (Disc 4) Battle Chess Collection | PC | | Original | | CD-ICD-355-4 | |
| Interplay Family Favorites (Disc 1) | PC | | CompUSA Exclusive Edition | | CD-ICD-1031-0 | |
| Interplay Family Favorites (Disc 2) | PC | | CompUSA Exclusive Edition | | CD-ICD-1031-1 | |
| Interplay Family Favorites (Disc 3) | PC | | CompUSA Exclusive Edition | | CD-ICD-1031-2 | |
| Interplay: Redefining the Game: E3 2001 Press CD | PC | | Press Kit | | CD-C95-2001-E3 | |
| Interplay's 10 Year Anthology: Classic Collection | PC | | Original | | | |
| Interplay's Select Family Entertainment Pack (Casino Master / Descent / Jigsaw Power / Puzzle Power / Solitaire Deluxe) | PC | | Original | | CD-C95-1130-3 | |
| Interplay's Select Family Entertainment Pack (Virtual Pool) | PC | | Original | | CD-C95-1130-0 | |
| Interstate '76 (Disc 1) (Install CD) | PC | | Gold Edition (The Interstate '76 Arsenal) | | 1000240.101.US | |
| Interstate '76 (Disc 2) (Play CD) | PC | | Gold Edition (The Interstate '76 Arsenal) | | 1000240.102.US | |
| Interstate '76: Nitro Pack Nitro Pack for Interstate '76 | PC | | The Interstate '76 Arsenal | | 1000240.103.US | |
| Interstate '82 | PC | | Original | | 1000386.101.US | |
| Introductory Games in German | PC | | Original | | | |
| Invictus: In the Shadow of Olympus (Disc 1) | PC | | Original | | CD-C95-1074-0 | |
| Invictus: In the Shadow of Olympus (Disc 2) | PC | | Original | | CD-C95-1074-1 | |
| Invisible Inc. (Installation Disc) Tactical Espionage: Invisible, Inc. | PC | Build 183969 | IndieBox | | | |
| Iron Helix | PC | 1.21E | Original | | HLXCD140 | |
| Iron Helix | PC | 1.25E | Original | | HLXCD140 1-126-40-101 | |
| Iron Maiden: Ed Hunter (Game Setup.) | PC | | Original | | C2K 63726/63728 | |
| Iron Maiden: Ed Hunter (Music CD 2: Game Setup) | PC | | Original | | C2K 63726/63728 | |
| Isis | PC | | | | FZ-SP0002 | |
| Island Casino (Disc 1) | PC | | Original | | 04-10309CD | |
| Island Casino (Disc 2) | PC | | Original | | 04-10309CD | |
| The Island of Dr. Brain | PC | 1.0 | SierraOriginals | | S103435 | |
| The Island of Dr. Brain | PC | 1.0 | SierraOriginals | | | |
| Island Peril | PC | 1.5b | Original | | | |
| Isle of the Dead | PC | 1.29 | CD-ROM Ten Pak | | | |
| It's Lizzie's Party Lizzie McGuire Enhanced CD 2 | PC | | McDonald's Happy Meal | | | |
| It's the Big Game, Charlie Brown | PC | | Original | | | |
| I Spy Junior | PC | 2.0.0.5 | Original | | P/N 910863 | |
| I Spy Fantasy | PC | 1.0 | Rerelease, Wendy's Kids Meal | | | |
| I-War (Disc 2) | PC | | Original, Soft Price, Special Edition | | 42031-921WRC, DEFIAPC52G/A2, IWARCDR2GB | |
| I-War (Disc 3) | PC | | Original, Soft Price, Special Edition | | 42031-931WRC, DEFIAPC52G/A3, IWARCDR3GB | |
| Icewind Dale II: Adventure Pack (Bonus Disc) | PC | | Pre-Order, Icewind Dale: Complete Collection, Icewind Dale: The Ultimate Collection | | W8523810 | |
| IL-2 Sturmovik: Forgotten Battles (Disc 2) | PC | | Original, Gold Pack, Rerelease | | 651802-CD2 | |
| Indiana Jones and the Infernal Machine (Disc 1) | PC | 1.0 | Original | | 3000020.101.UK, 6511830 | |
| Indiana Jones and the Infernal Machine (Disc 2) | PC | 1.0 | Original | | 3000020.102.UK, 6511831 | |
| Interplay Sports Baseball Edition 2000 | PC | | Original | | CD-C95-1027-0, CD-W95-1027-E | |
| I Was an Atomic Mutant! アトミックミュータント | PC | | Original | | P/N: 10239 | |
| Istoriya Ukrayiny 1 Історія України 1 | PC | | Original | | | |
| The Independent: Grand Master Sudoku | PC | | | | | |
| Interactive Magic | PC | | Demo | | | |
| Ishido | PC | | Original | | 318-0145 | |
| The Italian Job | PC | | Covermount | | SUN039c | |