Region | Title | System | Version | Edition | Languages | Serial | Status |
| Spinnaker Chara Colle: Hagane no Renkinjutsushi Vol. 2: CD/DVD Label Spinnaker キャラコレ 鋼の錬金術師 Vol.2 CD/DVD ラベル | PC | | Original | | | |
| Spinnaker Chara Colle Series: Hagane no Renkinjutsushi Vol. 1: Name Seal Spinnaker キャラコレシリーズ 鋼の錬金術師 Vol.1 ネームシール | PC | | Original | | | |
| Spinnaker Chara Colle Calendar: Hagane no Renkinjutsushi Spinnaker キャラコレカレンダー 鋼の錬金術師 | PC | | Original | | | |
| Spine Sense: The Interactive Back Protection Program | CDI | | Original | | | |
| SpinDrive Ping Pong | PS2 | 1.01 | Original | | SLES-52867 | |
| Spin Tail スピン・テイル | PSX | | Original | | SLPS 01461 | |
| Spin Jam | PSX | | Original | | SLUS-01250 | |
| Spin Jam | PSX | | Original | | SLES-02790 | |
| Spin Busta | PC | 1.0 | Original | | GS0003 | |
| Spike: The Hedgehog | PC | | Covermount | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Original | | | |
| Spike: The Hedgehog | PC | 1.0.0.1 | Dice | | DCG 012965 | |
| Spike: The Hedgehog | PC | 1.0.0.1 | | | APWCDR1033 | |
| Spielen mit Freundin | PC | | Original | | | |
| Spielekiste 2 | ACD | | Original | | | |
| Spiele für Windows 7, XP & Vista | PC | | Software Pyramide | | | |
| Spielbare Cheats Volume 27 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 26 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 25 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 24 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 23 | PS2 | 1.10 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 22 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 21 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 20 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 19 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 18 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 17 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 16 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spiel des Lebens | PC | | Original | | | |
| Spider: The Video Game | PSX | | Original | | SLUS-00230 | |
| Spider: The Video Game スパイダー | PSX | | Original | | SLPS 00852 | |
| Spider: The Video Game | PSX | | Original | | SLES-00682 | |
| Spider: The Video Game | PSX | | Original | | SLES-00681 | |
| Spider: The Video Game | PSX | | Original | | SLES-00117 | |
| Spider-Man: Web of Shadows (Final Press Kit) | PC | | Press Kit | | | |
| Spider-Man: The Sinister Six | PC | | Original | | 60020-9 | |
| Spider-Man: The Sinister Six Spider-Man: Die Gnadenlosen Sechs | PC | | Original | | | |
| Spider-Man: Kampen om Evigt Liv | PC | | Book Bundle | | CDJ 8002 | |
| Spider-Man: Angriff der Super-Schurken | VFLASH | | Original | | 093064(GER) | |
| Spider-Man Databank | PC | | Original | | | |
| Spider-Man Course-Poursuite à Manhattan | VFLASH | | Original | | 093065(FR) | |
| Spider-Man 2: The Game | PC | 1.0 | Original | | 32581.101.US | |
| Spider-Man 2: The Game | PC | | Covermount | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.IT | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.GM | |
| Spider-Man 2: The Game | PC | | Original | | 32581.101.UK | |
| Spider-Man 2: La Revanche d'Electro | PSX | | Platinum | | SLES-03624 … | |
| Spider-Man 2: Enter: Electro | PSX | Rev 1 | Original, Greatest Hits | | SLUS-01378 … | |
| Spider-Man 2: Enter: Electro | PSX | | Original | | SLUS-01378 | |
| Spider-Man 2: Enter: Electro スパイダーマン2 ~エンター:エレクトロ~ | PSX | | Original | | SLPM 87073 | |
| Spider-Man 2: Enter: Electro | PSX | | Original, Platinum | | SLES-03625 | |
| Spider-Man 2: Enter: Electro | PSX | Rev 1 | Original, Platinum, Promo | | SLES-03623 … | |
| Spider-Man 2: Enter: Electro | PSX | | Original | | SLES-03623 | |
| Spider-Man 2 | PC | | Demo | | | |
| Spider-Man 2 Человек-паук 2 | PC | | 1C: Kollekciya igrushek | | | |
| Spider-Man | MAC | | Original | | | |
| Spider-Man (Disc 2) | PC | 1.0 | Original | | 32249.102.US | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.US | |
| Spider-Man (Disc 1) | PC | 1.0 | Original | | 32249.101.US | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.US | |
| Spider-Man | DC | 1.000 | Original | | T-13008N | |
| Spider-Man | HS | 1.0 (USE1) | Original | | K6593-9609 | |
| Spider-Man | PC | | Original | | 31131.101.US | |
| Spider-Man | PSX | | Original, Greatest Hits | | SLUS-00875 … | |
| Spider-Man | PC | | Demo | | | |
| Spider-Man | PSX | | Platinum | | SLES-02890 … | |
| Spider-Man スパイダーマン | PSX | | Original, SuperLite 1500 | | SLPM 86739 … | |
| Spider-Man | PSX | | Platinum | | SLES-02889 … | |
| Spider-Man | PSX | | Original | | SLES-02888 … | |
| Spider-Man | PSX | | Platinum | | SLES-02887 … | |
| Spider-Man (Disc 2) | PC | | Original | | 32249.102.UK | |
| Spider-Man (Disc 1) | PC | | Original | | 32249.101.UK | |
| Spider-Man | DC | 1.000 | Original | | T-13011D-50 | |
| Spider-Man | PSX | | Original, Platinum | | SLES-02886 … | |
| Spider-Man | PC | | Original | | 31131.101.UK | |
| Spice World | PSX | | Original | | SLUS-00723 | |
| Spice World | PSX | | Original | | SCES-01234 | |
| Spice World | PSX | | Original | | SCES-01233 | |
| Spice World | PSX | | Original | | SCES-01232 | |
| Spice World | PSX | | Original | | SCES-01231 | |
| Spice World | PSX | | Original | | SCES-00883 | |
| Spice World | PSX | | Preview Version | | SCES-00883 | |
| Spice World | PSX | | Review | | | |
| Śpiąca Królewna | PC | | Covermount | | SELL 0161 | |
| Sphinix Gold | PC | | Original | | ROK 04 Art.-Nr. 6623 | |
| Spherical Worlds | ACD | | Original | | | |
| Sphere Racer | PC | | Original | | | |
| Sphere 360° | PSX | | Bundled with ASCII Sphere 360° Controller | | SLED-01711 | |
| Sphera: The Inner Journey | PC | 1.0 | Original | | 27791-CD | |
| The Speris Legacy | CD32 | | Original | | | |
| Spełnij Marzenia: Gra Piłkarska Pepsi | PC | | | | | |
| Spelvin Goolie Private Eyeball Spelvin Goolie Private Eyeball: The World's Greatest Left-Handed Detective | PC | 1.0 | Original | | ROW-10942 | |
| Spelunky | PC | | Fangamer (Collector's Edition) | | | |
| Speltajm: Djungelns kojigaste CD-ROM | PC | | Original | | | |
| Spells of Gold | PC | | Original | | CENEGA 163/2003 | |
| Spelling: 'SATS' Key Stage 2 | PC | 1999.12.1.1 | Original | | | |
| Spelling Home Tutor | PC | | | | | |
| SpellForce: Złota Edycja (Disc 4) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 3) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 2) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Złota Edycja (Disc 1) | PC | | Nowa eXtra Klasyka | | | |
| SpellForce: Zakon Switu (Disc 2) | PC | | | | | |
| SpellForce: The Order of Dawn: Songs of Winter SpellForce: The Order of Dawn: Songs of Winter: The Official Soundtrack to Breath of Winter | PC | | Limited Edition | | ROSPELLFOR0012LABST | |
| SpellForce: The Order of Dawn (Disc 2) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD2 v1.0 E, 28017-SM2 v1.0 F | |
| SpellForce: The Order of Dawn (Disc 1) | PC | 1.05 | Original, Store Manager Copy | | 28017-CD1 v1.0 F, 28017-SM1 v1.0 F | |
| SpellForce: The Order of Dawn (Disc 2) | PC | | Covermount | | ROSPELLFOR0003LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) | PC | | Covermount | | ROSPELLFOR0003LAB1 | |
| SpellForce: The Order of Dawn (Disc 2) (Installa CD) | PC | 1.52.61407 | Original | | ROSPELLFOR0027LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) (Installa/Esegui CD) | PC | 1.52.61407 | Original | | ROSPELLFOR0027LAB1 | |
| SpellForce: The Order of Dawn (Disc 3) (Install CD3) | PC | | Limited Edition | | ROSPELLFOR0012LAB3 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab2 | |
| SpellForce: The Order of Dawn (Disc 2) (Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD2) | PC | | Limited Edition | | ROSPELLFOR0012LAB2 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | 1.52.61407 | Hammerpreis | | ROSPELLFOR0024lab1 | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play) | PC | | Original | | JW002236 | |
| SpellForce: The Order of Dawn (Disc 1) (Install CD1 / Play CD) | PC | | Limited Edition | | ROSPELLFOR0012LAB1 | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Breath of Winter | PC | 1.30 | Original | | ROSPELLFOR0005LAB | |
| SpellForce: Gold Edition (Disc 3) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 2) | PC | 1.53.65731 | Original | | | |
| SpellForce: Gold Edition (Disc 1) | PC | 1.53.65731 | Original | | | |
| Spellcross: L'Ultima Battaglia | PC | | CD-ROM Classic Collection 7 | | | |
| Spellcasting: Party Pak | PC | 1.0 | Original | | | |
| Spell It Deluxe | PC | | Original | | | |
| Het Speelhuis van Muis | PC | | Original | | | |
| Speel Bridge 5 | PC | | Original | | | |
| Speel Bridge 4 | PC | | Original | | | |
| Speedy Zone 2 | PC | | Original | | 100-4045 | |
| Speedy Eggbert II Speedy Eggbert 2 | PC | 1.0 | Original | | | |
| Speedy Eggbert II | PC | 1.0 | Original | | | |
| Speedy Eggbert | PC | 1.1 | Original | | 02-9703-10 | |
| Speedway 2000 | PC | | Original | | | |
| Speedster | PC | | Dice | | DCG 005813, DMM 005837 | |
| Speedster | PC | | Original, Argentum Collection | | | |
| Speedster | PSX | | Original | | SLES-00575 | |
| SpeedRage | PC | 1.10 | 2in1 Pack | | | |
| SpeedRage (Game Disk) | PC | 1.10 | Original | | TFGD2159 | |
| SpeedRage (Slave Disk) | PC | 1.10 | Original | | TFGD2159 | |
| Speedlink Competition Pro USB: Sports Tournament Edition | PC | | Bundle Version Speedlink OEM | | SL-6603-SPORTS-EU | |
| Speedboat GP | PS2 | 1.01 | Original | | SLES-54074 | |
| Speedboat Attack | PC | 0.9.9.0 | Best Buys | | BB 004 | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | 0.9.9.0 | Covermount | | | |
| Speedboat Attack | PC | 0.9.9.0 | Budget | | MMICDR 5097 | |
| Speedboat Attack | PC | | Action-Games | | 80274 | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speedboat Attack | PC | 0.9.9.0 | Original | | | |
| Speedboat Attack | PC | 1.0.3.1 | Original | | | |
| Speedball 2100 | PSX | | Original | | SLUS-01218 | |
| Speedball 2100 | PSX | | Original | | SLES-02782 | |
| Speedball 2 | CD32 | | Original | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Speed Thief | PC | 1.0 | Original | | | |
| Speed Racer | PSX | | Original | | SLUS-00613 | |
| Speed Punks | PSX | | Original | | SCUS-94563 | |
| Speed Punks | PSX | | Demo | | SCUS-94572 | |
| Speed Mania e路狂飆 屏鵝公路篇 體驗版 | PC | | Demo | | | |
| Speed Machines 3 | PS2 | 1.03 | Original | | SLES-53920 | |
| Speed Machines | PSX | | Original | | SLES-03930 | |
| Speed Kings | PS2 | 1.00 | Original | | SLUS 20584 | |
| Speed Kings | PS2 | 1.00 | Original | | SLES-50848 … | |
| Speed King: Neo Kobe 2045 スピードキング | PSX | | Original | | SLPM 86013 | |
| Speed Haste | PC | | Budget | | MMICDR 5078, MMICDR 5114 | |
| Speed Haste | PC | 1.00 | Original | | A5475CXD | |
| Speed Haste | PC | | Rerelease | | | |
| Speed Haste | PC | | Pocket Price Games | | | |
| Speed Freaks (Misc Artwork: PC-CD 2nd July '99) | PC | | Press Kit | | | |
| Speed Freaks | PSX | | Original, Bundled with Multi Tap | | SCES-01763 | |
| Speed Freak | PC | | Covermount | | | |
| Speed Devils: Online Racing | DC | 1.002 | Original | | T-17718N | |
| Speed Devils: Online Racing | DC | 1.003 | Original | | T-17713D-50 | |
| Speed Devils | DC | 1.004 | Original | | T-17702N | |
| Speed Devils スピード・デビル | DC | 1.005 | Original | | T-17702M | |
| Speed Devils | DC | 1.004 | Original | | T-17702D-50 | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Covermount | | | |
| Speed Demons | PC | | Original | | Ref: 65702162 | |
| Speed Challenge: Jacques Villeneuve's Racing Vision | PS2 | 1.01 | Original | | SLES-51022 … | |
| Speed Busters: American Highways | PC | | Original | | | |
| Speed Busters | PC | 1.02 | Demo | | | |
| Speed Busters | PC | | Covermount | | | |
| Speed Busters | PC | 1.01 | Budget | | MMICDR 5706 | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Covermount | | | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Speed Busters | PC | | Ubi Soft Classique | | | |
| Speed Busters BGamer 045 (Disc 1) | PC | 1.01 | Focus Essential, Covermount | | ESS262 | |
| Speed Busters | PC | | Original | | | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 Rev.1 | |
| Speech Trainer V1.0 L10 スピーチ・トレーナー | FMT | | Original | | HMD-224 | |
| Spectrobes: Beyond the Portals (Electronic Press Kit) | PC | | Press Kit | | | |
| Spectre VR Classic | PC | | Original | | MQ 13-004-120 | |
| Spectre VR CD | MAC | | Original | | | |
| Spectre VR | PC | 1.07wp | Ultimate Game Collection | | | |
| Spectre VR | PC | | Megapak 2 | | | |
| Spectre VR | PC | 1.05 | Original | | | |
| Spectral vs. Generation スペクトラル VS ジェネレーション | PS2 | 1.02 | Original | | SLPM 62727 | |
| Spectral vs. Generation | PS2 | 1.00 | Original | | SLES-54687 | |
| Spectral Tower II スペクトラルタワーⅡ | PSX | | Original, Idea Factory Collection | | SLPS 01179 … | |
| Spectral Tower II スペクトラルタワーⅡ | PSX | | Taikenban | | SLPM 80209 | |
| Spectral Tower スペクトラルタワー | PSX | | Original | | SLPS 00476 | |
| Spectral Force: Itoshiki Jaaku スペクトラルフォース ~愛しき邪悪~ | PSX | | Original, Idea Factory Collection | | SLPS 02233 … | |
| Spectral Force: Aira Kourin スペクトラルフォース ~アイラ降臨~ | PC | 1.00 | Original | | ID NO.9666-78-01 | |
| Spectral Force 2 スペクトラルフォース2 | PSX | | Original, Idea Factory Collection | | SLPS 01628 … | |
| Spectral Force スペクトラルフォース | PSX | | Original, Idea Factory Collection | | SLPS 01056 … | |
| Spectral Force スペクトラルフォース | PSX | | Shokai Gentei Box | | SLPS 00969 | |
| Spectral Blade スペクトラルブレイド | PSX | | Original, Idea Factory Collection | | SLPS 02526 … | |
| Specnaz: proekt Volk (Disc 2) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: proekt Volk (Disc 1) Спецназ: проект «Волк» | PC | 1.0.1 | 1C: Kollekciya igrushek | | | |
| Specnaz: Antiterror. Missija na Balkanah (Disc 1) Спецназ: Антитеррор. Миссия на Балканах | PC | | Original | | | |
| Special Secret Data Disc | PC | | PSP Game Bundle | | | |
| Special Permit for Cabela's Big Game Hunter | PC | | Original | | | |
| Special Forces: Nemesis Strike (Disc 3) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 2) | PC | 1.0 | Original | | | |
| Special Forces: Nemesis Strike (Disc 1) (Game Disc) | PC | 1.0 | Original | | | |
| Special Forces | PS2 | 1.00 | Original | | SLES-54591 | |
| Special Forces | PC | 1.00 | Hit Squad: Regenerator | | REGEN020 | |
| Special Edition 4 Pack: Volume One | PC | | Original | | | |
| Special Disc with SegaSaturn Internet 2 SPECIAL DISC with SEGASATURN インターネット2 | SS | 1.020 | Hibaihin | | T-31303G | |
| Special & Delicious! Original CD-ROM | FMT | | Bundled with Book | | TAIYOU-001 | |
| Speccy Classix '98 Speccy Classix 1998 | PC | | | | | |
| Speccy Classix | PC | | Rerelease | | | |
| Spec Ops: Stealth Patrol | PSX | | Original | | SLUS-01131 | |
| Spec Ops: Stealth Patrol | PSX | | Original | | SLES-00844 | |
| Spec Ops: Rangers Lead the Way | PC | 1.0 | Original | | CD-RC008 | |
| Spec Ops: Rangers Lead the Way | PC | | Demo | | CD-RC008 | |
| Spec Ops: Ranger Team Bravo | PC | | Original | | CD-RC010 | |
| Spec Ops: Ranger Gold | PC | 1.0 | Original, Platinum Collection | | CD-RG-004 | |
| Spec Ops: Ranger Elite | PSX | | Original | | SLUS-01299 | |
| Spec Ops: Ranger Elite | PSX | | Original | | SLES-03157 | |
| Spec Ops: Ranger Assault | PC | | Covermount | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | 2.5 | Red Fly | | | |
| Spec Ops: Ranger Assault | PC | | Original | | 76896 428512 | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Extreme | | | |
| Spec Ops: Ranger Assault | PC | | Sold Out Software | | | |
| Spec Ops: Ranger Assault | PC | | Covermount | | CDE30_CDA | |
| Spec Ops: Platinum Collection (Disc 2) | PC | 1.0 | Original | | | |
| Spec Ops: Covert Assault | PSX | | Original | | SLUS-01420 | |
| Spec Ops: Covert Assault | PSX | | Original | | SLES-03515 | |
| Spec Ops: Airborne Commando | PSX | | Original | | SLUS-01447 | |
| Spec Ops: Airborne Commando | PSX | | Original | | SLES-03891 | |
| Spec Ops II: U.S. Army Green Berets | PC | | Budget, BIS Collezione CD-ROM | | 10019 | |
| Spec Ops II: U.S. Army Green Berets | PC | | Original | | | |
| Spec Ops II: Operation Bravo | PC | | Lock 'N' Load | | | |
| Spec Ops II: Omega Squad | DC | 1.008 | Original | | T-41704N | |
| Spec Ops II: Omega Squad | DC | 1.002 | Original | | T-45004D-50 | |
| Spec Ops II: Green Berets | PC | 1.00.000 | Original | | CD-RG-003 | |
| Spearhead | PC | | Covermount | | | |
| Spearhead סימולטור טנקים | PC | 1.0.0.1 | Original | | | |
| Spearhead | PC | | Original | | | |
| Spearhead | PC | | Pocket Price | | | |
| Spearhead | PC | | Original | | | |
| Spear of Destiny: Super CD Pack | PC | | Super CD Pack | | | |
| Spear of Destiny | PC | 1.4 | Original | | | |
| Spear of Destiny | PC | | Ultimate Game Collection | | | |
| Spawn: The Eternal | PSX | | Original | | SCUS-94204 | |
| Spawn: The Eternal | PSX | | Preview Version | | SCUS-94204 | |
| Spawn: The Eternal スポーン ジ・エターナル | PSX | | Original | | SLPS 01400 | |
| Spawn: The Eternal | PSX | | Original, Promo | | SCES-01056 | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-1216N | |
| Spawn: In the Demon's Hand スポーン イン ザ デーモンズ ハンド | DC | 1.003 | Original | | T-1216M | |
| Spawn: In the Demon's Hand | DC | 1.000 | Original | | T-36816D-50 | |
| Spaß am Turnierreiten Equestriad 2001 | PC | | Original | | | |
| Spartan XX スパルタン イグゼクス | PC | | Original | | | |
| Spartan | PC | | Sold Out Software | | | |
| Spartan | PC | | Original | | JFC000784 | |
| Sparrow Garden: Namco Mahjong ナムコマージャン スパローガーデン | PSX | | Original | | SLPS 00074 | |
| Sparkling Feather スパークリング・フェザー | PC-FX | | Original | | FXNHE739 | |
| Spaguetti Party: La Familia Pomodoro | PC | | Covermount | | | |
| Spacetanks | PC | 1.0 | Pepper Games | | | |
| SpaceStationSim | PC | 2.0.1.1 | Original | | | |
| Spaceship Warlock | PC | 1.1.3 "MPC" | Ultimate Game Collection | | | |
| Spaceship Warlock | PC | 1.1.3 | Original | | | |
| Spaceship Warlock | MAC | | Original | | CDRM 403300 | |
| SpaceHaste 2 SpaceHaste | PC | 1.32 | TopWare Just 4Fun | | | |
| SpaceHaste 2 SpaceHaste: The Next Levels | PC | 2.001 | Covermount | | | |
| SpaceHaste 2 | PC | | Original | | | |
| SpaceHaste BGamer 070 (Disc 2) | PC | | Covermount | | | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Spacebound Space Bound | PC | | Original | | | |
| Space-Dude: Der Retter des Universums | PC | | Original | | | |
| Space War Attack | PS2 | 1.01 | Original | | SLES-53915 | |
| Space Tripper Space Defender | PC | 1.4 | Pocketware | | #8 | |
| Space Tripper | PC | | Original | | APWCDR1014 | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Space Station Manager Космоград | PC | 1.2.1 Rus | Original | | | |
| Space Sniper Maya (Disc 2) スペーススナイパー マヤ | PC | | Original | | GOR-0004 2/2 | |
| Space Sniper Maya (Disc 1) スペーススナイパー マヤ | PC | | Original | | GOR-0004 1/2 | |
| Space Sirens | PC | | Original | | SKU: UN017 | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | PC | Rev A | Bundle Version OEM | | RVL 13-004-073 | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | 3DO | | Original | | | |
| Space Shuttle | PC | | Original | | CDRM1109910 | |
| Space Shuttle | MAC | | Original | | CDRM1087300 | |
| Space Shuttle スペースシャトル | PHOTO-CD | 1.1 | Original | | C02H | |
| Space Shot | PSX | | Original | | SLUS-01308 | |
| Space Safari | CDI | 01.08 | Original | | 811 0035 | |
| Space Rogue スペース・ローグ | FMT | | Original | | HMB-180 | |
| Space Rider | PSX | | Original | | SLES-04126 | |
| Space Rebellion | PS2 | 1.01 | Original | | SLES-54593 | |
| Space Rangers | PC | 1.7.2 | Cinemaware Marquee | | 02-1506-12 | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Space Raiders 스페이스 레이더스 VER.2 | PS2 | 1.00 | Original | | SLKA 15002 | |
| Space Raiders スペースレイダース | PS2 | 1.01 | Original | | SLPM 62275 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.052 | Original | | 833114330/S311430 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | | Original | | | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.032 | Original | | S343BBZZ12ZZZ | |
| Space Quest: Collection Series (Disc 2) | PC | | Original | | | |
| Space Quest: Collection Series (Disc 1) | PC | | Original | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SoftKey, SierraOriginals | | CDRM SQU344AE-CD, S4840220012ZZ | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest IV: Roger Wilco and the Time Rippers Space Quest IV | PC | 1.0 | Original | | CDRM SQU344AE-CD | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | CD 7011 SPI | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | SierraOriginals | | | |
| Space Quest IV: Roger Wilco and the Time Rippers | PC | 1.0 | 5 ft. 10 PAK Vol. 2 | | | |
| Space Quest I: Roger Wilco in the Sarien Encounter | PC | | Kixx XL | | | |
| Space Quest Collection | PC | 1.0 | Original, Sierra Classic Collection | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.11 | Original | | | |
| Space Quest 6: Roger Wilco: The Spinal Frontier Space Quest 6: Roger Wilco in The Spinal Frontier | PC | 1.0 | Original | | S329430 | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | Original | | S4330520Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | | | S6460520212ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | MAC | | Original | | S4330250Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | 1.0 | Original | | S4330220Z12ZZ | |
| Space Quest 6: Roger Wilco in the Spinal Frontier | PC | | SierraOriginals | | S6460220Z12ZZ | |
| Space Quest 6: Roger Wilco aux Frontières de l'Espace Intervertébral | PC | 1.11 | SierraOriginals | | S6460120Z12ZZ | |
| Space Pirates | 3DO | | Original | | ALG595001 | |
| Space Ofera Agga Ruter: Kyoufu no Uchuu Majo Space Ofera アッガ・ルター 恐怖の宇宙魔女 | PC | | Original | | | |
| Space Museum スペース・ミュージアム | FMT | | Original | | | |
| Space Marisar スペースマリサー | PC | 1.00 | Original | | | |
| Space Marines: Der Stählerne Kaiser | PC | | All You Can Play: Adventure & Fantasy | | | |
| Space Marines (Disc 2) | PC | | Classic Line | | | |
| Space Marines (Disc 1) | PC | | Classic Line | | | |
| Space Jam | SS | 1.000 | Original | | T-8125H | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam | PSX | | Original | | SLUS-00243 | |
| Space Jam スペース・ジャム | SS | 1.000 | Original | | T-8119G | |
| Space Jam スペースジャム | PSX | | Original | | SLPS 00697 | |
| Space Jam | SS | 1.001 | Original | | T-8125H-50 | |
| Space Jam | PC | 1.00 | Original | | | |
| Space Jam | PSX | | Original | | SLES-00284 | |
| Space Invaders: The Original Game スペースインベーダー | PC | | Original | | | |
| Space Invaders: The Original Game スペース・インベーダー | PCE | | Original | | NAPR-1050 | |
| Space Invaders: The Original Game Space Invaders '95 | PC | | Original | | | |
| Space Invaders: Invasion Day | PS2 | 1.00 | Original | | SLES-51746 | |
| Space Invaders X | PC | 1.0.0 | Sourcenext Selection | | | |
| Space Invaders X スペース・インベーダーX | PSX | | Original | | SLPM 86419 | |
| Space Invaders Anniversary 스페이스 인베이더 애니버서리 | PS2 | 1.01 | Original | | SLKA 15025 | |
| Space Invaders Anniversary スペースインベーダー アニバーサリー | PS2 | 1.02 | Original | | SLPM 62354 | |
| Space Invaders Anniversary | PS2 | 1.01 | Original | | SLES-52313 … | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 EUROPEAN | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Space Invaders 2000 スペースインベーダー2000 | PSX | | Original | | SLPM 86153 | |
| Space Invaders | PC | 1.0 | Original | | 1000916.101.US | |
| Space Invaders | PSX | | Original | | SLUS-00928 | |
| Space Invaders | PSX | | Review | | | |
| Space Invaders スペース・インベーダー | SS | 1.001 | Original, Puzzle Bobble 2X & Space Invaders | | T-1107G, T-1111G | |
| Space Invaders スペースインベーダー | PSX | | Original | | SLPS 00940 | |
| Space Invaders スペースインベーダー | PC | | Yuuyuu 1,480-yen (Publishing Distribution) | | KMK-1210, MKY-055 | |
| Space Invaders | PC | 1.1 | Xplosiv | | XP-1867 EUROPEAN | |
| Space Invaders | PC | | Original | | 1000916.101.UK | |
| Space Invaders | PSX | | Original | | SLES-02144 | |
| Space Invaders | PC | | Covermount | | | |
| Space Invada!! Type Shinai to Tama ga Denai. SPACE INVA打!! / SPACE INVADERS!! タイプしないとタマが出ない。 | PC | | Original | | EF-SIV01 | |
| Space in Motion: Future Trade | PC | 1.01 | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | | Original | | 7373 | |
| Space Hulk: Vengeance of the Blood Angels | PSX | | Original | | SLUS-00205 | |
| Space Hulk: Vengeance of the Blood Angels | SS | 1.000 | Original | | T-5007H-50 | |
| Space Hulk: Vengeance of the Blood Angels | PC | | Original | | E348EDED | |
| Space Hulk: Vengeance of the Blood Angels | PSX | | Original | | SLES-00207 | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | | Original | | | |
| Space Hulk | PC | | Original | | E2105CCD | |
| Space Hack | PC | 1.02 | Original | | | |
| Space Griffon VF-9 | PSX | | Original | | SLUS-00153 | |
| Space Griffon VF-9 スペースグリフォンVF‐9 | PSX | Rev 1 | Original | | SLPS 00012 | |
| Space Griffon VF-9 スペースグリフォンVF‐9 | PSX | | Original, Sample | | SLPS 00012 | |
| Space Fishermen スペースフィッシャーメン | PS2 | 1.00 | Original | | SCPS 11025 | |
| Space Empires V Космическая Империя V | PC | 1.66 | Original | | | |
| Space Empires V | PC | 1.30 | Covermount | | | |
| Space Empires V | PC | 1.20 | Original | | EI-2171 EUROPEAN | |
| Space Dynagon Kai スペース大納言(改 | PC | | Original | | MSCD-0026 | |
| Space Dudes | PC | | Original | | | |
| Space Dogs: Adventure to the Moon Белка и Стрелка. Лунные приключения | PC | 1.0.0 | Original | | | |
| Space Debris | PSX | | Original | | SCES-02433 | |
| Space Debris | PSX | | Original, Promo | | SCES-02432 | |
| Space Debris | PSX | | Review | | SCES-02431 | |
| Space Debris | PSX | | Original | | SCES-02431 | |
| Space Debris | PSX | | Original | | SCES-02430 | |
| Space Debris | PSX | | Original | | SCES-02290 | |
| Space Crusade | PC | | | | | |
| Space Colony | PC | | Original | | | |
| Space Colony | PC | | Interactive Demo | | | |
| Space Colony (Disc 2) (Jugar) | PC | | Original | | | |
| Space Colony (Disc 1) (Instalación) | PC | | Original | | | |
| Space Colony (Install) | PC | | Green Pepper | | | |
| Space Colony (Play) | PC | | Green Pepper | | | |
| Space Colony | PC | | Original | | | |
| Space Clash: The Last Frontier | PC | | Sold Out Software | | | |
| Space Clash | PC | | Original | | M-25324-1999 | |
| Space Clash Space Clash: Das letzte Imperium | PC | | Original | | | |
| Space Channel 5 Theme Music: Mexican Flyer スペース・チャンネル5 | DC | 1.080 | Not for Sale | | | |
| Space Channel 5 Part 2 スペース・チャンネル5 パート2 | DC | 2.000 | Original | | HDR-0190 | |
| Space Channel 5 | DC | 1.000 | Original | | 51051 | |
| Space Channel 5 スペース・チャンネル5 | DC | 1.001 | Original, Dorikore | | HDR-0029, HDR-0140 | |
| Space Channel 5 スペース・チャンネル5 | DC | 0.203 | Taikenban | | 610-7368 | |
| Space Channel 5 | DC | 1.001 | Original | | MK-51051-50 | |
| Space Channel 5 | DC | 1.000 | Sample | | 952-0083-50 | |
| Space Bunnies Must Die! | PC | | Original | | CD-RC004 | |
| Space Bunnies Must Die! | PC | | Demo | | MSDE-37216 | |
| Space Bucks: Spedition Galactica | PC | | Game-Pack 3 | | 80222 | |
| Space Bucks | PC | | Original | | | |
| Space Bucks | PC | | Original | | S4710520Z12ZZ | |
| Space Blaster Swarm | PC | | Original | | | |
| The Space Bar (Disc 3) | PC | 1.0 | Original | | 115-7J | |
| The Space Bar (Disc 3) | PC | | Original | | 115-7C | |
| The Space Bar (Disc 3) | MAC | | Original | | 115-7F | |
| The Space Bar (Disc 2) | PC | 1.0 | Original | | 115-7I | |
| The Space Bar (Disc 2) | PC | | Original | | 115-7B | |
| The Space Bar (Disc 2) | MAC | | Original | | 115-7E | |
| The Space Bar (Disc 1) | PC | 1.0 | Original | | 115-7G | |
| The Space Bar (Disc 1) | MAC | 1.0 | Original | | 115-7H | |
| The Space Bar (Disc 1) | PC | | Original | | 115-7A | |
| The Space Bar (Disc 1) | MAC | | Original | | 115-7D | |
| The Space Bar (Disc 3) | PC | | Original | | | |
| The Space Bar (Disc 2) | PC | | Original | | | |
| The Space Bar (Disc 1) | PC | | Original | | | |
| Space Arcade Collection | PC | 1.0 | Original | | 11-4150-10 | |
| Space Adventure: With Buzz Aldrin & Tom McDonough | MAC | | Original, Bundle Version Apple OEM | | CDRM1239480 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015-50 | |
| Space Adventure Cobra: The Shooting コブラ・ザ・シューティング | PSX | | Original | | SLPS 00312 | |
| Space Adventure Cobra: Kokuryuuou no Densetsu コブラ ~黒竜王の伝説~ | PCE | | Original | | HCD8004 | |
| Space Adventure Cobra II: Densetsu no Otoko コブラⅡ ~伝説の男~ | PCE | | Original | | HCD1014 | |
| Space Ace CD-ROM (PC and Compatibles) Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM (For Macintosh Computers) Don Bluth's Space Ace | MAC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | | Original | | | |
| Space Ace CD-ROM Don Bluth's Space Ace | PC | 2.0 | | | SANSARL-01 | |
| Space Ace | 3DO | RE-1 | Original | | | |
| Space Ace | PC | | Rerelease | | L1SPAACE1B | |
| Space Ace | MCD | | Original | | T-121025 | |
| Space Ace | MCD | | Demo | | | |
| Space Ace | AJCD | | Original | | | |
| Space Ace | 3DO | | Original | | | |
| Space Ace | CDI | | Original, Demonstration Disc | | 310-690-059-2, 310690059-2 | |
| Space Ace | PC | | Jackson Libri | | | |
| Space Ace | PC | 2.1 | All You Can Play: Adventure & Fantasy | | | |
| Space Ace | 3DO | | Bundled with Magazine (Demo) | | | |
| Space Ace | CDI | | Original, For Demonstration Only | | 810 0073, 818 0017 | |
| Soviet Strike | PSX | Rev 1 | Greatest Hits | | SLUS-00061 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H | |
| Soviet Strike | PSX | | Original | | SLUS-00061 | |
| Soviet Strike ソビエト・ストライク | SS | 1.000 | Original | | T-10621G | |
| Soviet Strike ソビエトストライク | PSX | | Original | | SLPS 00735 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-18 | |
| Soviet Strike | PSX | | Original, Platinum | | SLES-00509 | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-09 | |
| Soviet Strike | PSX | | Original, Platinum | | SLES-00508 | |
| Soviet Strike | PSX | EDC | EA Classics: Value Series | | SLES-00507 … | |
| Soviet Strike | SS | 1.000 | Original | | T-5013H-50 | |
| Soviet Strike | PSX | | Original, Platinum, EA Classics | | SLES-00507 … | |
| Souzou Sozai: Umi Vol. 1 創造素材 海 Vol.1 | PHOTO-CD | | Original | | SEVI-1049 | |
| Souzou Sozai: Europe no Mado Vol. 2 創造素材 ヨーロッパの窓 Vol.2 | PHOTO-CD | | Original | | ERV2 | |
| SouthPeak Interactive E3 2000 Electronic Press Kit | PC | | Press Kit | | | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art": Special CD-ROM サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" SPECIAL CD-ROM | PC | | Original | | ORRS-1 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 3) (Theater) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86410 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 2) (Library) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86409 | |
| Southern All Stars: Space MOSA "Space Museum of Southern Art" (Disc 1) (Museum) サザンオールスターズ SPACE MOSA "SPACE MUSEUM OF SOUTHERN ART" | PSX | | Original | | SLPM 86408 | |
| South Park: Chef's Luv Shack | DC | 1.000 | Original | | T-8105N | |
| South Park: Chef's Luv Shack | PSX | | Original | | SLUS-00997 | |
| South Park: Chef's Luv Shack | DC | 1.000 | Original | | T-8105D-50 | |
| South Park: Chef's Luv Shack | PSX | | Original | | SLES-01972 … | |
| South Park: Chef's Luv Shack | PSX | | Demo | | SLED-02576 | |
| South Park: Chef's Luv Shack | PC | | Original | | CD194190.00-EUR | |
| South Park Rally | DC | 1.001 | Original | | T-8116N | |
| South Park Rally | PSX | | Original | | SLUS-00984 | |
| South Park Rally | PSX | | Original | | SLES-02352 | |
| South Park Rally | DC | 1.001 | Original | | T-8112D-50 | |
| South Park Rally | PSX | | Acclaimed Range, Value Series | | SLES-02690 … | |
| South Park Rally | PC | | Original | | CD194197.01-ENG | |
| South Park | PC | | Original | | | |
| South Park | PSX | | Original | | SLUS-00936 | |
| South Park | PC | | Original | | | |
| South Park | PC | | Original | | | |
| South Park | PSX | | Original | | SLES-02158 | |
| Soutenryuu: The Arcade 蒼天龍 THE ARCADE | PS2 | 1.01 | Original | | SLPM 62310 | |
| Souten no Shiroki Kami no Kura: Great Peak 蒼天の白き神の座 -GREAT PEAK- | PSX | | Original | | SCPS 10058 | |
| Soushun: Tsutaetai Koto 想瞬 ーつたえたいことー | PC | | Original | | | |
| Sousei Seiki Devadasy: Repeator Amara 創世聖紀デヴァダシー REPEATOR AMARA | PC | | PC Game Best Series | | | |
| Souryuu 創龍 | PSX | | Original, Renkaban | | SLPS 00642 … | |
| sourirE | PC | 1.00 | Original | | | |
| Soundtrap | CDI | 1.06 | Original | | 811 0032 | |