Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original | | SLES-02510 | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original, Twin Pack | | SLUS-00621 … | |
| Simple 1500 Series Vol. 81: The Ren'ai Adventure: Okaeri! SIMPLE1500シリーズ Vol.81 THE 恋愛アドベンチャー おかえりっ! | PSX | | Original | | SLPM 86972 | |
| Space Adventure Cobra: The Shooting コブラ・ザ・シューティング | PSX | | Original | | SLPS 00312 | |
| Startling Adventures: Kuusou 3x Daibouken スタートリング・アドベンチャーズ~空想3×大冒険~ | PSX | | Original | | SLPM 86809 | |
| Stray Sheep: The Adventure of Poe & Merry ストレイシープポーとメリーの大冒険 | PSX | | Original | | SLPS 02035 | |
| Stray Sheep: The Adventure of Poe & Merry ストレイシープポーとメリーの大冒険 | PSX | Rev 1 | Triple Pleasures, Reprint | | SLPM 86547 … | |
| Suchie-Pai Adventure: Doki Doki Nightmare (Disc 1) スーチーパイ・アドベンチャー ~ドキドキナイトメア~ | PSX | | Original | | SLPS 01264 | |
| Suchie-Pai Adventure: Doki Doki Nightmare (Disc 2) スーチーパイ・アドベンチャー ~ドキドキナイトメア~ | PSX | | Original | | SLPS 01265 | |
| Super Adventure Rockman (Disc 1) (Episode 1 "Tsuki no Shinden") スーパーアドベンチャーロックマン | PSX | | Original | | SLPS 01051 | |
| Super Adventure Rockman (Disc 2) (Episode 2 "Shitou! Wily Numbers") スーパーアドベンチャーロックマン | PSX | | Original | | SLPS 01052 | |
| Super Adventure Rockman (Disc 3) (Episode 3 "Saigo no Tatakai!!") スーパーアドベンチャーロックマン | PSX | | Original | | SLPS 01053 | |
| SuperLite 1500 Series: Märchen Adventure: Cotton 100% SuperLite 1500 シリーズ コットン100% | PSX | | Original | | SLPM 87211 | |
| Sea Monsters: A Prehistoric Adventure National Geographic: Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLES-55046 | |
| Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLUS-21741 | |
| Simple 2000 Series Vol. 13: Onna no Ko no Tame no: The Ren'ai Adventure: Garasu no Mori SIMPLE2000シリーズ Vol.13 女の子のための THE 恋愛アドベンチャー ~硝子の森~ | PS2 | 1.01 | Original | | SLPM 62234 | |
| Simple 2000 Series Vol. 34: The Ren'ai Horror Adventure: Hyouryuu Shoujo SIMPLE2000シリーズ Vol.34 THE 恋愛ホラーアドベンチャー 漂流少女 | PS2 | 1.02 | Original | | SLPM 62343 | |
| Simple 2000 Series Vol. 9: The Ren'ai Adventure: Bittersweet Fools SIMPLE2000シリーズ Vol.9 THE 恋愛アドベンチャー BITTERSWEET FOOLS | PS2 | 1.01 | Original | | SLPM 62207 | |
| Super Monkey Ball Adventure | PS2 | 1.01 | Original | | SLES-53701 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLES-53804 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLUS 21289 | |
| Shonen Jump's One Piece: Grand Adventure | PS2 | 1.01 | Original | | SLES-54165 | |
| Shonen Jump's One Piece: Grand Adventure | PS2 | 1.01 | Original | | SLUS 21435 | |
| Simple 2000 Series Vol. 38: Otoko no Tame no Bible: The Yuujou Adventure: Hotaru Soul SIMPLE2000シリーズ Vol.38 漢のためのバイブル THE 友情アドベンチャー ~炎多留・魂~ | PS2 | 1.02 | Original | | SLPM 65393 | |
| Simple 2000 Series Vol. 71: The Fantasy Ren'ai Adventure: Kanojo no Densetsu, Boku no Sekiban SIMPLE2000シリーズ Vol.71 THE ファンタジー恋愛アドベンチャー ~彼女の伝説、僕の石版~ | PS2 | 1.00 | Original | | SLPM 65874 | |
| Sinbad Adventure wa Enomoto Kanako de Dou desu ka シンドバッドアドベンチャーは榎本加奈子でどうですか | PS2 | 1.02 | Original | | SLPS 25420 | |
| Springdale Springdale Riding Adventures | PS2 | 1.01 | Original | | SLES-55610 | |
| Stuart Little 3: Big Photo Adventure | PS2 | 1.02 | Original | | SCES-53422 … | |
| Stuart Little 3: Big Photo Adventure 스튜어트 리틀 3: 빅 포토 어드벤처 | PS2 | 1.00 | Original | | SCKA 20067 | |
| Stuart Little 3: Big Photo Adventure | PS2 | 1.01 | Original | | SLUS 21341 | |
| Super Monkey Ball Adventure | PS2 | 1.01 | Original | | SLUS 21272 | |
| Skylanders: Spyro's Adventure | PS3 | 01.00 | Starter Pack | | BLES-01751 | |
| Skylanders: Spyro's Adventure | PS3 | 01.01 | Starter Pack | | BLES-01272 | |
| Skylanders: Spyro's Adventure スカイランダーズ スパイロの大冒険 | PS3 | 01.00 | Starter Pack | | BLJM 61044 | |
| Skylanders: Spyro's Adventure | PS3 | 01.00 | Starter Pack | | BLUS-30779 | |
| Sonic World Adventure ソニック ワールドアドベンチャー | PS3 | 01.00 | Original | | BLJM 60112 | |
| Super Monkey Ball Adventure | PSP | 1.01 | Original, PSP Essentials | | ULES-00364 | |
| Super Monkey Ball Adventure | PSP | 1.02 | Original | | ULUS-10132 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015-50 | |
| The Space Adventure: Cobra: The Legendary Bandit | MCD | | Original | | T-143015 | |
| Suchie-Pai Adventure: Doki Doki Nightmare (Disc 1) スーチーパイ・アドベンチャー ~ドキドキ・ナイトメア~ | SS | 1.003 | Original, Special Package-ban | | T-5713G, T-5715G | |
| Suchie-Pai Adventure: Doki Doki Nightmare (Disc 2) スーチーパイ・アドベンチャー ~ドキドキナイトメア~ | SS | 1.003 | Original, Special Package-ban | | T-5713G, T-5715G | |
| Super Adventure Rockman (Disc 1) (Episode 1: Tsuki no Shinden) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Original | | T-1225G | |
| Super Adventure Rockman (Disc 1) (Episode 1: Tsuki no Shinden) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Rerelease | | T-1241G | |
| Super Adventure Rockman (Disc 2) (Episode 2: Shitou! Wily Numbers) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Original | | T-1225G | |
| Super Adventure Rockman (Disc 2) (Episode 2: Shitou! Wily Numbers) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Rerelease | | T-1241G | |
| Super Adventure Rockman (Disc 3) (Episode 3: Saigo no Tatakai!!) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Original | | T-1225G | |
| Super Adventure Rockman (Disc 3) (Episode 3: Saigo no Tatakai!!) スーパー・アドベンチャー・ロックマン | SS | 1.000 | Rerelease | | T-1241G | |
| Simple 2000 Series DC Vol. 01: Bittersweet Fools: The Ren'ai Adventure SIMPLE2000シリーズDC Vol.01 BITTERSWEET FOOLS THE 恋愛アドベンチャー | DC | 1.002 | Original | | T-47401M | |
| Simple 2000 Series DC Vol. 04: Okaeri! The Ren'ai Adventure SIMPLE2000シリーズDC Vol.04 おかえりっ! THE 恋愛アドベンチャー | DC | 1.003 | Original | | T-47403M | |
| Sonic Adventure | DC | 1.003 | Original | | MK-51000-50 | |
| Sonic Adventure ソニックアドベンチャー | DC | 1.007 | Original, Sample | | HDR-0001 | |
| Sonic Adventure | DC | 1.000 | Trial Version for E3 | | HDR-0001 | |
| Sonic Adventure | DC | 1.004 | Original | | 51000 | |
| Sonic Adventure | DC | 1.005 | Original, Sega All Stars | | 51000 | |
| Sonic Adventure 2 | DC | 1.002 | Beta | | MK-5111750 | |
| Sonic Adventure 2 | DC | 1.008 | Original | | MK-51117-50 | |
| Sonic Adventure 2 ソニックアドベンチャー2 | DC | 1.002 | Taikenban | | 610-8057 | |
| Sonic Adventure 2 ソニックアドベンチャー2 | DC | 1.008 | 10th Anniversary Birthday Pack | | HDR-0165 | |
| Sonic Adventure 2 | DC | 1.008 | Original | | 51117 | |
| Sonic Adventure 2: The Trial | DC | 1.001 | Demo | | 610-7994-50 | |
| Sonic Adventure 2: The Trial ソニックアドベンチャー2 体験版 | DC | 1.000 | Demo | | 51100, HDR-0129 | |
| Sonic Adventure International ソニックアドベンチャー・インターナショナル | DC | 1.003 | Original | | HDR-0043 | |
| Sonic Adventure: Limited Edition | DC | 1.002 | Limited Edition, Hollywood Video Rental | | SDC-51014 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZE-USA | |
| Shonen Jump's One Piece: Grand Adventure | GC | | Original | | DL-DOL-GOQE-USA | |
| Sonic Adventure 2: Battle | GC | | Original, Player's Choice | | DL-DOL-GSNP-EUR, DL-DOL-GSNP-EUR-01 | |
| Sonic Adventure 2: Battle ソニックアドベンチャー2 バトル | GC | | Original | | DL-DOL-GSBJ-JPN | |
| Sonic Adventure 2: Battle | GC | | Original, Player's Choice | | DL-DOL-GSNE-USA | |
| Sonic Adventure DX ソニック アドベンチャー DX デラックス | GC | | Original | | DL-DOL-GASJ-JPN | |
| Sonic Adventure DX: Director's Cut | GC | Rev 1 | Original, Player's Choice | | DL-DOL-GXSP-EUR | |
| Sonic Adventure DX: Director's Cut | GC | | Original, Player's Choice | | DL-DOL-GXSE-USA | |
| Star Fox Adventures | GC | | Original | | DL-DOL-GSAP-EUR | |
| Star Fox Adventures | GC | Rev 1 | Original, Player's Choice | | DL-DOL-GSAP-EUR, DL-DOL-GSAP-EUR-01 | |
| Star Fox Adventures スターフォックスアドベンチャー | GC | | Original | | DL-DOL-GSAJ-JPN | |
| Star Fox Adventures スターフォックスアドベンチャー | GC | Rev 1 | Original | | DL-DOL-GSAJ-JPN | |
| Star Fox Adventures | GC | | Original | | DL-DOL-GSAE-USA | |
| Star Fox Adventures | GC | Rev 1 | Player's Choice | | DL-DOL-GSAE-USA | |
| Super Monkey Ball Adventure | GC | | Original | | DL-DOL-G3LP-EUR | |
| Super Monkey Ball Adventure | GC | | Original | | DL-DOL-G3LE-USA | |
| Safari Adventures: Africa | WII | | Original | | RVL-RFWP-EUR | |
| Safari Adventures: Africa | WII | | Original | | RVL-RFWE-USA-B0 | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7P-EUR | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Original | | RVL-SS3U-AUS-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Beta | | | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Original | | RVL-RIPE-USA | |
| Skylanders: Spyro's Adventure | WII | | Starter Pack | | RVL-SSPY-BRA-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPP-EUR-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPP-EUR-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPP-EUR-B2 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPX-SCN-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPX-SCN-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPX-SCN-B2 | |
| Skylanders: Spyro's Adventure | WII | | Starter Pack | | RVL-SSPE-USA-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPE-USA-B1 | |
| Smart Series Presents: Jaja's Adventure | WII | | Original | | RVL-R67E-USA-B0 | |
| Sonic World Adventure ソニック ワールドアドベンチャー | WII | | Original | | RVL-RSVJ-JPN | |
| Story Hour: Adventures | WII | | Original | | RVL-R3AP-EUR | |
| Story Hour: Adventures | WII | | Original | | RVL-R3AE-USA | |
| Super Mario Wii 2: Galaxy Adventure Together 슈퍼 마리오 Wii 2 갤럭시 어드벤처 투게더 | WII | | Original | | RVL-SB4K-KOR-B0 | |
| Super Mario Wii: Galaxy Adventure 슈퍼 마리오 Wii 갤럭시 어드벤처 | WII | | Original, Nintendo Selects | | RVL-RMGK-KOR, RVL-RMGK-KOR-B0 | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.0 | Original | | PCO519CD | |
| Safecracker: The Ultimate Puzzle Adventure | PC | 1.01 | Original | | PCO519CD | |
| Scholastic's The Magic School Bus: Volcano Adventure: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3 | | 0401 Part No. X08-06054 | |
| Sea Adventures | PC | | Microforum | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Sold Out Software | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Plane Adventures Sea Plane Adventures for FS2002/2004 | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Sesame Street Search & Learn Adventures | PC | | Original, Software for the fun of it | | EOA844AE-CD, KES005 | |
| Shutter Island Shutter Island: The Adventure Game | PC | | Original | | | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Silent Steel (Disc 1) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 2) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 3) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Silent Steel (Disc 4) Silent Steel: A Cinematic Strategy Adventure | PC | | Original | | | |
| Simon the Sorcerer's Game Pack featuring Swampy Adventures | PC | | Original | | | |
| Skylanders: Spyro's Adventure | PC | | Press Kit | | | |
| Slots Adventure: War for Olympus | PC | 1.0 | Original | | | |
| Snapshot Adventures: Secret of Bird Island | PC | | Original | | P/N 61191-CD | |
| Softgold Presents: LucasArts Top Adventures CD-ROM Edition | PC | | Original | | | |
| Sonic Adventure DX (Disc 1) ソニック アドベンチャー DX デラックス | PC | 1.0.0.9 | Bundle Version MSI OEM | | 610-8428, 673-04094 | |
| Sonic Adventure DX (Disc 2) ソニック アドベンチャー DX デラックス | PC | 1.0.0.9 | Bundle Version MSI OEM | | 610-8428, 673-04095 | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | | Original | | SEGA-PC002-EU | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | | Sold Out Software | | SOC000849 | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.0.0.9 | Original | | SEGA-PC002-EU/1 | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | | Original | | SEGA-PC002-EU | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | | Sold Out Software | | SOC000849-1 | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.0.0.9 | Original | | SEGA-PC002-EU/2 | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.009 | Sonic PC Collection | | SEGA-PC002-EU, SEGA-PC002/1-EU | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.009 | Sonic PC Collection | | SEGA-PC002-EU, SEGA-PC002/2-EU | |
| Sonic Adventure DX: Director's Cut (Disc 1) | PC | 1.0.0.9 | Original | | 35033.101.US | |
| Sonic Adventure DX: Director's Cut (Disc 2) | PC | 1.0.0.9 | Original | | 35033.102.US | |
| Sorting Adventures: Interactive Activities | PC | | Original | | AAP899, PP463 | |
| Space Dogs: Adventure to the Moon Белка и Стрелка. Лунные приключения | PC | 1.0.0 | Original | | | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 | |
| Speed / Space Adventure / Undersea Adventure | PC | | Bundle Version Packard Bell OEM | | 170159 Rev.1 | |
| Spy Kids Learning Adventures: The Candy Conspiracy | PC | | Original | | 03962 | |
| Spy Kids Learning Adventures: The Nightmare Machine | PC | | Original | | 03963 | |
| Star Fox Adventures: Game Preview CD | PC | | Promo | | | |
| Star Trek: Klingon (Disc 1) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | 1.0 | Original | | | |
| Star Trek: Klingon (Disc 2) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | 1.0 | Original | | | |
| Star Trek: Klingon (Disc 1) (Installation) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon (Disc 2) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | | Original | | | |
| Star Trek: Klingon (Disc 3) Star Trek: Klingon: The Ultimate Interactive Adventure | PC | 1.0 | Original | | | |
| Star Wars: Jar Jar's Journey Adventure Book | PC | 1.0 | Original | | #3520530 | |
| Strange Adventures in Infinite Space | PC | | Cheapass Games | | | |
| Stuart Little Learning Adventures: His Adventures in Wordland (Disc 2) | PC | 1.0 | Original | | 381676-CD2 | |
| Stuart Little: Big City Adventures Stuart Little: Big City Adventures CD-ROM Game | PC | | Original | | Product # 99716 | |
| Stuart Little: Big City Adventures | PC | | Replay Kids | | 1008166 | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| The Sims 2: World Adventure (Expansion Pack) The Sims 2: Bon Voyage (Expansion Pack) | PC | 1.10.0.111 | Original | | MXX07705691D | |
| Spore: Galactic Adventures | PC | | Original | | MXX09206599D | |
| Spore: Galactic Adventures | PC | 1.0 | Original | | MXX09206599D | |
| Spore: Galactic Adventures | PC | 1.0 | Original | | 1535407 | |
| Star Wars Galaxies: The Complete Online Adventures (Bonus DVD) | PC | | Original | | 41149.102.00 | |
| Star Wars Galaxies: The Complete Online Adventures (Disc 1) | PC | | Original | | 41149.101.00 | |
| Star Wars Galaxies: The Complete Online Adventures (Disc 1) | PC | | Original | | 8131830 | |
| The Sims 3: World Adventures The Sims 3: Мир Приключений | PC | | Original | | MXX09207028D | |
| The Sims 3: World Adventures (Expansion Pack) | PC | 0.2.0.56 | Original, The Sims 3 Expansion Bundle | | 1539307 | |
| Skylanders: Spyro's Adventure | PC | | | | 33366101EU | |
| Skylanders: Spyro's Adventure | PC | 1.0 | Starter Pack | | 33366010US | |
| Space Adventure Cobra II: Densetsu no Otoko コブラⅡ ~伝説の男~ | PCE | | Original | | HCD1014 | |
| Space Adventure Cobra: Kokuryuuou no Densetsu コブラ ~黒竜王の伝説~ | PCE | | Original | | HCD8004 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | XBOX | | Original | | AV-080 | |
| Skylanders: Spyro's Adventure | XBOX360 | | Not for Resale | | AV-2219 | |
| Skylanders: Spyro's Adventure | XBOX360 | | Starter Pack | | AV-2219 | |
| Snoopy's Grand Adventure | XBOX360 | | Original | | AV-2338 | |
| Sonic World Adventure ソニック ワールドアドベンチャー | XBOX360 | | Original | | SE-2066 | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| Space Adventure: With Buzz Aldrin & Tom McDonough | MAC | | Original, Bundle Version Apple OEM | | CDRM1239480 | |
| Sandy's Circus Adventure | CDI | | Original | | 690 0222 | |
| Sandy's Circus Adventure | CDI | | Original, Demonstration Disc | | 310-690-022-2, 310690022-2, 699 022-2 | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093083(UK) | |