| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Shutokou Battle Gaiden: Super Technic Challenge: Drift King e no Michi
首都高バトル外伝 スーパーテクニックチャレンジ ~ドリフトキングへの道~ | PSX | | Original |  | SLPS 00573 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
| Simple 1500 Jitsuyou Series Vol. 18: Kanji Quiz: Kanji Kentei ni Challenge
ＳＩＭＰＬＥ１５００実用シリーズ Ｖｏｌ．１８ 漢字・クイズ ～漢字検定にチャレンジ～ | PSX | | Original | | SLPM 87072 |  |
 | Suzuki Alstare Challenge | PSX | | Original |  | SLES-02221 | |
 | Sven-Göran Eriksson's World Challenge | PSX | | Original |  | SLES-03867 | |
| Simple 2000 Series Vol. 46: The Kanji Quiz: Challenge! Kanji Kentei
ＳＩＭＰＬＥ２０００シリーズ Ｖｏｌ．４６ ＴＨＥ 漢字クイズ チャレンジ！ 漢字検定 | PS2 | 1.02 | Original | | SLPM 62474 | |
| Soccer Life! We are Challengers to Europe
サッカー選手育成シミュレーション サッカーライフ！ Ｗｅ ａｒｅ ｃｈａｌｌｅｎｇｅｒｓ ｔｏ ＥＵＲＯＰＥ | PS2 | 1.02 | Original | | SLPS 20350 | |
| Speed Challenge: Jacques Villeneuve's Racing Vision | PS2 | 1.01 | Original | | SLES-51022 … | |
| Sprint Car Challenge
Sprint Car Challenge: The Power & the Glory | PS2 | 1.03 | Original |     | SLES-52774 | |
| Supercar Street Challenge | PS2 | 1.01 | Original | | SLES-50419 | |
| Supercar Street Challenge | PS2 | 1.00 | Original | | SLES-50420 | |
 | Supercar Street Challenge | PS2 | 1.00 | Original | | SLES-50421 | |
| Supercar Street Challenge
スーパーカー ストリートチャレンジ | PS2 | 1.20 | Original | | SLPM 62239 | |
 | Supercar Street Challenge | PS2 | 1.00 | Original | | SLUS-20012 | |
| Sven-Göran Eriksson's World Challenge | PS2 | 1.01 | Original | | SLES-50852 | |
| Soccer Life 2: We are Challengers to Europe
サッカーライフ２ Ｗｅ ａｒｅ ｃｈａｌｌｅｎｇｅｒｓ ｔｏ ＥＵＲＯＰＥ | PS2 | 1.02 | Original | | SLPS 25521 | |
| Summer Athletics: The Ultimate Challenge | PS2 | 1.00 | Original | | SLUS 21786 | |
| Super-Bikes Riding Challenge | PS2 | 1.01 | Original | | SLES-54222 | |
| Suzuki Super-Bikes II: Riding Challenge | PS2 | 1.00 | Original | | SLUS 21500 … | |
| Ski-Doo Snowmobile Challenge | PS3 | 01.06 | Original | | BLES-01486 | |
| Ski-Doo Snowmobile Challenge | PS3 | 01.04 | Original | | BLUS-30272 | |
| Summer Challenge: Athletics Tournament | PS3 | 01.01 | Original | | BLES-01011 … | |
| Supercar Challenge | PS3 | 01.05 | Original | | BLES-00581 | |
| Superstars V8: Next Challenge | PS3 | 01.01 | Original | | BLES-00771 | |
| Simple 2500 Series Portable!! Vol. 7: The Doko Demo Kanji Quiz: Challenge! Kanji Kentei 2006
ＳＩＭＰＬＥ２５００シリーズポータブル！！ Ｖｏｌ．７ ＴＨＥ どこでも漢字クイズ ～チャレンジ！漢字検定２００６～ | PSP | 1.00 | Original | | ULJS 00077 | |
| Spelling Challenges and More! | PSP | 1.00 | Original | | ULUS 10255 | |
| Speed Challenge: Jacques Villeneuve's Racing Vision | GC | | Original | | DL-DOL-GSZP-EUR | |
| Ski-Doo Snowmobile Challenge | WII | | Beta | | | |
| Ski-Doo Snowmobile Challenge | WII | | Original | | RVL-R87E-USA-B0 | |
| Smiley World: Island Challenge | WII | | Original | | RVL-RIDP-EUR | |
| Smiley World: Island Challenge | WII | | Original | | RVL-RIDE-USA-B0 | |
| Summer Athletics: The Ultimate Challenge | WII | | Original | | RVL-RU3E-USA, RVL-RU3E-USA-B0 | |
| Summer Challenge: Athletics Tournament | WII | | Original | | RVL-RE6P-EUR-B0 | |
 | Safari Hunter: Safari Hunt Challenge | PC | 1.00 | Microforum | | | |
 | SD Qlympics
Olympic Challenge | PC | | Grabit | | GDL031 | |
| Shock Price 500 Game Series: Golf: Challenge at Mauna Lani Resort
ＳＨＯＣＫ ＰＲＩＣＥ ５００ ＧＡＭＥ ＳＥＲＩＥＳ ゴルフ チャレンジ アット マウナラニリゾート | PC | | Rerelease | | SSRX 3072 | |
| Shock Price 500 Game Series: Golf: Challenge at Mauna Lani Resort
ＳＨＯＣＫ ＰＲＩＣＥ ５００ ＧＡＭＥ ＳＥＲＩＥＳ ゴルフ チャレンジ アット マウナラニリゾート | PC | | Original | | SSRX 3072 | |
| Smart Games Puzzle Challenge 3 | PC | 1.0 | Original | | 99254 | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
| Smart Games: Challenge 1 | PC | | Original | | P/N:DSGC1CD0001 | |
| Smart Games: Challenge 1 | PC | | Rerelease | | 99168 | |
 | Sports Challenge Pack 2 | PC | | Encyclopedia Games 2009-10 Deluxe Edition | | | |
| Star Wars: Yoda's Challenge | PC | | Original | | 3520030 | |
| Star Wars: Yoda's Challenge Activity Center | PC | | Demo | | #3529030 | |
| The Starfire Soccer Challenge | PC | | Original | | 109-10-2000 | |
| Strategy Challenges Collection 1 | PC | 1.04 | Original, OEM Bundle | | 102771 | |
 | The Sudoku Challenge | PC | | Sold Out Software | | 08099PCG | |
| The Sudoku Challenge! Collection | PC | | Original | | | |
| Die Sudoku Challenge! | PC | | Software Pyramide | | EI-1956 EUROPEAN | |
| The Sudoku Challenge! | PC | 10.1 | Sold Out Software | | | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
| Summer & Winter Olympic Challenge | PC | | Original | | ROM-53360 | |
 | Superbike Challenge | PC | | Covermount | | | |
| Superbike Challenge | PC | | Racing 1500 Series | | RC-100744 | |
 | Supercar Street Challenge | PC | | Xplosiv | | EI-1477 EUROPEAN | |
| Survival: The Ultimate Challenge | PC | 1.0 | Original | | 31209.101.US | |
| Super-Bikes Riding Challenge | PC | 1.0 | Revival | | REV130 | |
| Ski-Doo Snowmobile Challenge | XBOX360 | | Original | | VG-2001 | |
| Summer Athletics: The Ultimate Challenge | XBOX360 | | Original | | CV-2004 | |
| Summer Challenge: Athletics Tournament | XBOX360 | | Original | | RL-2014 | |
| Superstars V8: Next Challenge | XBOX360 | | Original | | LS-2008 | |
| Super Street Fighter II X: Grand Master Challenge
スーパー・ストリート・ファイターⅡＸ | 3DO | | Original, Power-Up Campaign | | FZ-SJ3851 | |
 | Super Street Fighter II X: Grand Master Challenge
スーパー・ストリート・ファイターⅡＸ | 3DO | | Demonstration-ban, Bundled with Magazine (4 Character Demo Disc) | | FZ-JJ9DSX-4I | |
| Super Street Fighter II: The New Challengers
スーパー・ストリート・ファイターⅡ | FMT | | Sample | | | |
| Super Street Fighter II: The New Challengers
スーパー・ストリート・ファイターⅡ | FMT | 941011 | CD-ROM-ban (Shokai Gentei: 6-button Pad-tsuki) | | HMF-162 | |
| Sail to Win! A Rules and Tactics Challenge | CDI | | Original | | 819 0042 | |
| SmartKids Challenge One | VIS | | Original | | 25-6176 | |
