| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original |  | | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | Sanyo Pachinko Paradise
三洋パチンコパラダイス | PSX | | Original |  | SLPS 02164 | |
| Sanyo Pachinko Paradise 2: Umi Monogatari Special
三洋パチンコパラダイス２ ～海物語・スペシャル～ | PSX | | Original | | SLPS 02389 |  |
| Sanyo Pachinko Paradise 3: Wan Wan Daikoushin
三洋パチンコパラダイス３ ～わんわん大行進～ | PSX | | Original | | SLPS 02633 | |
| Sanyo Pachinko Paradise 4: Sushiya da Gen-san!!
三洋パチンコパラダイス４ ～寿司屋だ源さん！！～ | PSX | | Original | | SLPS 02988 | |
| Sanyo Pachinko Paradise 5: Uki Uki Tairyoubata
三洋パチンコパラダイス５ ～ウキウキ大漁旗～ | PSX | | Original | | SLPS 03190 | |
| Sanzennen Shokudou: Shoku Culture Simulation Game
三千年食堂 食カルチャーシミュレーションゲーム | MAC | | Original | | G012JAP-M | |
| Saraba Uchuu Senkan Yamato: Ai no Senshitachi (Disc 1)
さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02761 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshitachi (Disc 2)
さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02762 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshitachi (Disc 3)
さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02763 | |
 | Sargon Chess | CDI | | Original | | 310690030-2, 690 030-2, 690 0302, 699 030-2, 812 0024, 814 0042, 815 0018 | |
| Sargon Chess | CDI | | Original, Original: Longbox | | 310690030-2 | |
| Sargon Chess | CDI | | Beta | | 310-690-030-2 | |
| Sargon V: World Class Chess
サルゴンⅤ | FMT | | Original | | HMD-191 | |
| Saru Suberi
サルすべり | PC | | Original | | | |
| Saru! Get You!
サルゲッチュ | PSX | | Tentou-you Taikenban | | PCPX 96166 | |
 | Saru! Get You!
サルゲッチュ | PSX | | Taikenban | | PAPX 90079 … | |
| Saru! Get You!
サルゲッチュ | PSX | | Original | | SCPS 10091 … | |
 | SAS: Anti-Terror Force | PC | | |   | | |
| SAS: Secure Tomorrow | PC | | Covermount |  | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | eXtra Klasyka XK HIT | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | Original | | | |
| Sąsiedzi z Piekła Rodem 1 + 2 | PC | | eXtra Klasyka Next | | | |
 | SAT.1 Superball | PC | | Original | | | |
| SatelliTV / Doki Doki Shutter Chance: Koi no Puzzle o Kumitatete
サテライティービー ／ どきどきシャッター・チャンス ～恋のパズルを組み立てて～ | PSX | | Taikenban | | SLPM 80190 | |
| Satisfashion: Rock the Runway | WII | | Original | | RVL-SS5E-USA-B0 | |
 | SATS Test & Learn English Key Stage 2 (Disc 1) | PC | | Original | | | |
| SATS Test & Learn English Key Stage 2 (Disc 2) | PC | | Original | | | |
| SATS Test & Learn Maths Key Stage 2 (Disc 1) | PC | | Original | | | |
| SATS Test & Learn Maths Key Stage 2 (Disc 2) | PC | | Original | | | |
| SATS Test & Learn Science Key Stage 2 (Disc 1) | PC | | Original | | | |
| SATS Test & Learn Science Key Stage 2 (Disc 2) | PC | | Original | | | |
| Satsui no Shoumei: In the 1st Degree (Disc 1)
殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078A | |
| Satsui no Shoumei: In the 1st Degree (Disc 2)
殺意の証明 イン ザ ファースト ディグリー | MAC | | Original | | IP-078B | |
| Satsui no Shoumei: In the 1st Degree: Making CD-ROM
殺意の証明 イン ザ ファースト ディグリー メイキングＣＤ－ＲＯＭ | PC | | Hibaihin | | IP-081M | |
| Saturday Night Live Goes Political | PC | | Original | | | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Savage Arena | PC | | Dixons | | | |
| Savage: The Battle for Newerth | PC | | Bundle Version ASUS OEM | | V471 | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
 | Savannens hjältar
Hugo: Savannens hjältar | PC | | Rerelease |  | 147-2SWE/D | |
| Save on Software CD-ROM Volume 1: The Ultimate Shareware Collection
$ave on $oftware CD-ROM Volume 1: The Ultimate Shareware Collection | PC | | | | | |
| Sayonara
さよなら | PC | | Taikenban | | | |
| Sayonara no Mukougawa
さよならの向こう側 | FMT | | Original | | CBF-0008 | |
| SBFR the Best 2: Black | PC | | Original | | SSEB-0042 | |
| SBFR the Best 3: Kirby First History | PC | | Original | | SSEB-0054 | |
| SBFR the Best 4: PKMN First History | PC | | Original | | SSEB-0055 | |
| SBK 08: Superbike World Championship | XBOX360 | | Original | | LS-2001 | |
 | SBK 08: Superbike World Championship | PC | | Covermount |   | | |
| SBK 09: Superbike World Championship | XBOX360 | | Original | | LS-2004 | |
| SBK 2011: FIM Superbike World Championship | XBOX360 | | Original | | LS-2021 | |
| SBK Generations | XBOX360 | | Original | | LS-2033 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK X: Superbike World Championship | XBOX360 | | Original | | LS-2007 | |
| SBK X: Superbike World Championship: JP Edition | XBOX360 | | Original | | LS-2007 | |
| SBK: Superbike World Championship | XBOX360 | | Original | | CN-2005 | |
 | Sbornik e'roticheskix igr: Special'naya redakciya (Disc 1)
Сборник эротических игр: Специальная редакция | PSX | | Unlicensed |  | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 2)
Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Scaler | GC | | Original | | DL-DOL-GKUE-USA | |
 | Scaler | XBOX | | Original | | TT-122 | |
 | SCAR: Squadra Corse Alfa Romeo | PC | | Big Bytes | | 50004PCG | |
| SCAR: Squadra Corse Alfa Romeo | XBOX | | Original | | LS-002 | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| SCAR: Squadra Corse Alfa Romeo | PC | | Original | | | |
| SCAR: Squadra Corse Alfa Romeo
SCAR: Спортивная команда Альфа Ромео | PC | | Original | | | |
| Scarab
S.C.A.R.A.B. | PC | | Original | | EAE08801181D | |
| Scarab
S.C.A.R.A.B. | PC | | Original | | 7545 | |
| Scarface: The World Is Yours | XBOX | | Original | | VU-063 | |
| Scarface: The World Is Yours (Scarface EPK) | PC | | Press Kit | | | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCU-AUS-B0 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCP-EUR | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCD-NOE | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCE-USA | |
| Scarface: The World Is Yours | XBOX | | Original | | VU-063 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 300202 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scary Poems for Rotten Kids | MAC | | Original | | CDRM 397200 | |
| Scavenger 4
スカベンジャー４ | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217 | |
| Scavenger 4
スカベンジャー４ | FMT | | Demo-ban | | HME-918 | |
| The Scavenger Hunt Adventure Series: Africa | MAC | | Original | | | |
| SCEA Gamers Day 2002: Press Info | PC | | Press Kit | | | |
 | Le Sceau de l'Empereur | PC | | Gold Master DVD-R | | | |
| SCEE Press Event: Tokyo Game Show 2005: September 2005 | PC | | Press Kit | | | |
| SCEE Press Information: Corporate & Hardware: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 1: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Press Information: Software Disc 2: Autumn 2002 | PC | | Press Kit | | | |
| SCEE Software Brochure + Press Information: E3 2003 | PC | | Press Kit | | | |
| Scenariomania
Scenariomania Vol. 1 | PC | | Original | | | |
| The Scene Archive: 1988-1998 | ACD | | Original | | | |
 | Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2038 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCX-CAN-B0 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCP-UKV-B0 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2039 | |
| Scene It? Bright Lights! Big Screen! | XBOX360 | | Original | | WR-2037 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCE-USA-B0 | |
| Scene It? Ciak! Si Gira!
Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCI-ITA-B0 | |
| Scene It? Ciak! Si Gira!
Scene It? Ciak! Si Gira! Nuovissime domande e curiosità sul mondo del cinema | XBOX360 | | Original | | WR-2044 | |
| Scene It? Cinéma en folie
Scene It? Cinéma en folie: Le jeu sur le cinéma | XBOX360 | | Original | | MS-2098 | |
 | Scene It? Estrellas en la Pantalla Gigante | WII | | Original | | RVL-SSCS-ESP-B0 | |
| Scene It? Estrellas en la Pantalla Gigante | XBOX360 | | Original | | WR-2041 | |
