Region | Title | System | Version | Edition | Languages | Serial | Status |
| Scrabble | PC | | General Mills | | | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PSX | | Original | | SLUS-00903 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Original | | 99002 | |
| Scrabble | PSP | 1.00 | Original | | ULUS-10412 | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble Complete | PC | | Cosmi | | CDRZ652D1, SJ122005 | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble: Champion Edition | PC | | Rerelease | | 04562 | |
| Scrabble: Champion Edition | PC | | Original | | 11191A-CD v1.0 S | |
| Scrabble: Champion Edition | PC | 1.0S | Rerelease | | 11191B-CD | |
| Scrabble: Crossword Game | PALM | | Original | | 358-0901-10 | |
| Scrabble: Crossword Game | PALM | | Original | | 358-1001-10 | |
| Scrabble: Crossword Game | MAC | 1.0.0.52 | Original | | P/N 10328-5 | |
| Scramble Cobra | 3DO | | Original | | FZ-SM0404 | |
| Scratches | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Original | | | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Screamer | PC | | White Label | | | |
| Screamer | PC | | White Label | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Scribblenauts Unlimited | PC | | Original | | 5000145356 | |
| The Scroll | PC | | | | | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| SD Gundam Force: Showdown! | PS2 | 1.01 | Original | | SLUS 20698 | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.0 | Original | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| Sea Monsters: A Prehistoric Adventure | PS2 | 1.01 | Original | | SLUS-21741 | |
| Sea-Doo Hydro Cross | PSX | | Original | | SLUS-01149 | |
| SeaBlade | XBOX | | Original | | VU-023 | |
| Seal of Evil | PC | | Original | | 904066DVD | |
| Seal of the Pharaoh | 3DO | | Original | | FZ-SM1751 | |
| Seaman | DC | 1.001 | Original | | 51048 | |
| Search & Rescue 3 | PC | 1.0.0.0 | Original | | | |
| Search and Rescue Search and Rescue Helicopter Flight Sim | PC | | Original | | | |
| Search for the Golden Dolphin Search for the Golden Dolphin: An Interactive 3-D Adventure | PC | | | | | |
| Season Ticket Baseball 2003 | PC | 1.0 | Original | | 04-23416CDSL | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZE-USA | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLUS 21289 | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Second Sight | PS2 | 1.00 | Original | | SLUS-21033 | |
| Secret Agent Barbie | PC | 1.0c | Original | | S7127810 | |
| Secret Agent Clank | PS2 | 1.00 | Original | | SCUS 97623 | |
| Secret Agent Clank | PSP | 1.01 | Original, Greatest Hits, Secret Agent Clank + Daxter UMD Dual Pack | | UCUS 98697 … | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Margrave Manor | PC | | Original | | | |
| The Secret of Monkey Island | MCD | | Limited Run Games | | | |
| The Secret of Monkey Island | MCD | | Original | | T-60035 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| The Secret of Monkey Island | PC | 2.3 | Original, Bundle Version OEM | | 2147010-590001 / I 042 | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| The Secret of the Silver Earring (Disc 1) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD1 | |
| The Secret of the Silver Earring (Disc 2) Sherlock Holmes: The Secret of the Silver Earring | PC | | Original | | 652106-CD2 | |
| The Secret Saturdays: Beasts of the 5th Sun | WII | | Original | | RVL-R85E-USA-B0 | |
| The Secret Saturdays: Beasts of the 5th Sun | PSP | 1.00 | Original | | ULUS-10443 | |
| The Secret Saturdays: Beasts of the 5th Sun | PS2 | 1.01 | Original | | SLUS-21896 | |
| Secret Service | PS2 | 1.01 | Original | | SLUS 21836 | |
| Secret Service: Security Breach | PC | 1.1 | Original | | 31035.101.US | |
| Secret Weapons of the Luftwaffe | PC | | Original | | 2156010-590001/I042, CDRM1003790 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLUS 20762 | |
| Secret Weapons over Normandy (Disc 1) | PC | 1.0 | Original | | 2101830 | |
| Secret Weapons over Normandy (Disc 2) | PC | 1.0 | Original | | 2101831 | |
| Secret Weapons over Normandy (Disc 3) | PC | 1.0 | Original | | 2101832 | |
| Secret Weapons over Normandy (Disc 4) (Play Disc) | PC | 1.0 | Original | | 2101833 | |
| The Secrets of Alamût (Disc 1) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Alamût (Disc 2) The Secrets of Alamût: The Legend 2 | PC | | | | | |
| The Secrets of Atlantis (Disc 1) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 2) | PC | | Original | | PC0549CD SNY 2.0 | |
| The Secrets of Atlantis (Disc 3) | PC | | Original | | PC0549CD SNY 2.0 | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| The Secrets of Hosea Freeman | VIS | | Original | | 25-6144 | |
| Secrets of the Ark: A Broken Sword Game (Disc 1) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 2) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the Ark: A Broken Sword Game (Disc 3) | PC | 1.0 | Original | | PCO535CD | |
| Secrets of the East | PC | | Scholastic | | P/N CDR9909538 | |
| Secrets of the Luxor (Disc 1) | PC | | Original | | | |
| Secrets of the Luxor (Disc 2) | PC | | Original | | | |
| Section 8 | PC | | Original | | 50027-LBL | |
| Section Z Capcom Classics: Section Z | PC | 1.0 | PDA | | | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 2: 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Mysteries 2 | PC | | Original | | | |
| Seek and Destroy Seek & Destroy | PC | | Original | | EPSAD01 | |
| Seek and Destroy Seek & Destroy | PC | 1.0 | Original | | J230D | |
| Seek and Destroy | PS2 | 1.01 | Original | | SLUS 20606 | |
| Sega Ages Volume 1 | SS | 1.001 | Original | | T-12707H | |
| Sega Bass Fishing | WII | | Original | | RVL-RBTE-USA | |
| Sega Bass Fishing | DC | 1.000 | Original, Sega All Stars | | 51006 | |
| Sega Bass Fishing 2 | DC | 1.080 | Original | | 51166 | |
| Sega Bass Fishing Duel Bass Fishing Duel: Sega Sports | PS2 | 1.02 | Original | | SLUS 20339 | |
| Sega Classics Arcade Collection | MCD | 1.00 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Collection | PS2 | 1.01 | Original | | SLUS 21009 | |
| Sega Genesis Classic Collection: Gold Edition | PC | 1.0.019 | Original | | | |
| Sega Genesis Collection | PS2 | 1.01 | Original | | SLUS 21542 | |
| Sega Genesis Collection | PSP | 1.01 | Original, SEGA Fun Pack | | ULUS-10192 | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega GT 2002 | XBOX | | Original | | SE-003 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega Marine Fishing | DC | 1.001 | Original | | 51096 | |
| Sega Puzzle Pack | PC | | Expert Software | | 682701.101.US | |
| Sega Puzzle Pack | PC | | Rerelease | | 85091 / FS22923 | |
| Sega Puzzle Pack | PC | | Original | | 85091 | |
| Sega Rally 2 Sega Rally 2: Sega Rally Championship | DC | 1.003 | Original | | 51019 | |
| Sega Rally 2 (Disc 1) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0919 | |
| Sega Rally 2 (Disc 2) Sega Rally 2: Sega Rally Championship | PC | | Original | | 40924-0819 | |
| Sega Rally Championship | PC | 1.0 | Original | | 85048 | |
| Sega Rally Championship | SS | 1.006 | Original, Sega Saturn NetLink Bundle | | 80012, 81207 | |
| Sega Rally Championship Plus Netlink Edition | SS | 1.001 | Net Link Game Pack | | 81215, 81608 | |
| Sega Rally Revo | PS3 | 01.00 | Original | | BLUS-30068 | |
| Sega Rally Revo | PSP | 1.00 | Original | | ULUS-10311 | |
| Sega Smash Pack | PC | | Original | | 85087 | |
| Sega Smash Pack | PC | 1.0 | Expert Software | | 682601.101.US | |
| Sega Smash Pack 2 | PC | | Original, Sonic Action 4 Pack | | 30107.101.US | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Smash Pack: Volume 1 | DC | 1.002 | Original, Bundled with DC | | 51146 | |
| Sega Soccer Slam | XBOX | | Original | | SE-020 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSE-USA | |
| Sega Soccer Slam | PS2 | 1.00 | Original | | SLUS-20509 | |
| Sega Sports Tennis | PS2 | 1.01 | Original | | SLUS 20480 | |
| Sega Superstars | PS2 | 1.00 | Original | | SLUS 20999 | |
| Sega Superstars Tennis | WII | | Original | | RVL-RT5E-USA | |
| Sega Superstars Tennis | PS3 | 01.01 | Original | | BLUS-30123 | |
| Sega Superstars Tennis | PS2 | 1.01 | Original | | SLUS 21733 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | 85067 | |
| Sega Touring Car Championship | SS | 1.001 | Original, Sample | | 81216 | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3E-USA-B0 | |
| Sengoku Rance 戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Sensei 2 | PC | | Original | | GC-007 | |
| Sentient | PSX | | Original | | SCUS-94110 | |
| Sentient | PC | | Original | | | |
| Sentinel Returns | PSX | | Original | | SLUS-00604 | |
| Sentinel Returns | PC | 1.0 | Original | | CDAC-148200 | |
| Sentinel: Descendants in Time (Disc 1) | PC | | Original | | | |
| Sentinel: Descendants in Time (Disc 2) | PC | | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Rerelease | | CD-W58-1103-1 | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Original | | CD-W58-1103-0 | |
| Septerra Core: Legacy of the Creator | PC | 1.02 | Dual Jewel | | CD-C95-1298-1 | |
| Serious Sam | XBOX | | Original | | TT-004 | |
| The Serious Sam Collection | XBOX360 | | Original | | VQ-2010 | |
| Serious Sam Gold (Disc 1) | PC | 1.05 | Original | | | |
| Serious Sam Gold (Disc 2) | PC | 1.05 | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 1) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam: Next Encounter | PS2 | 1.01 | Original | | SLUS-20907 | |
| Serious Sam: Next Encounter | GC | Rev 1 | Original | | DL-DOL-G3BE-USA | |
| Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam: The First Encounter | PALM | | Original | | | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| Serious Sam: The First Encounter | PC | 1.02 | Bundle Version Gainward OEM | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original | | | |
| The Serpent of Isis: The First 2 Chapters The Serpent of Isis / The Serpent of Isis: Your Journey Continues | PC | | Original | | 33393010US | |
| Serpent of Isis: Your Journey Continues | PC | | Big Fish Games Backup CD | | | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street Sports | PSX | | Original | | SLUS-01180 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS4E-USA-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original, Twin Pack | | SLUS-00621 … | |
| Sesame Street: Elmo's Musical Monsterpiece: The Videogame | WII | | Original | | RVL-SSSE-USA-B0 | |
| Sesame Street: Elmo's Number Journey | PSX | | Original, Twin Pack | | SLUS-00622 … | |
| Sesame Street: Ready, Set, Grover! with Elmo: The Videogame | WII | | Original | | RVL-SESE-USA-B0 | |
| Settlers II, The: Veni, Vidi, Vici | MAC | 1.0.0 | Original | | | |
| The Settlers IV The Settlers: Fourth Edition | PC | | Original | | 610335-CD | |
| The Settlers: Heritage of Kings | PC | 1.01.0163 | Original | | 682011-DVD | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original | | | |
| The Settlers: Rise of an Empire | PC | 1.0.4140.0 | Scholastic | | P/N DVD5107350 | |
| Seven Games of the Soul (Disc 1) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 2) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 3) Faust | PC | | Original | | | |
| Seven Games of the Soul (Disc 4) Faust | PC | | Original | | | |
| Seven Kingdoms | PC | 1.1 | Colección 'Juega y Aprende' | | | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Seven Samurai 20XX | PS2 | 1.00 | Original | | SLUS 20621 | |
| Seventh Cross Evolution | DC | 1.000 | Original | | T-41301N | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Original | | T-6201 | |
| Sewer Shark | MCD | Rev 1 | Original | | T-6201 | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-0 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-1 | |
| Shadow Company: Left for Dead | PC | 1.0 | Original | | 5051802 | |
| Shadow Force: Razor Unit | PC | | Original | | 30851.101.US | |
| Shadow Force: Razor Unit | PC | | Special Forces Pack | | SFRU-0414 | |
| Shadow Hearts | PS2 | 1.00 | Original | | SLUS 20347 | |
| Shadow Hearts: Covenant (Disc 1) | PS2 | 1.00 | Original | | SLUS 21041 | |
| Shadow Hearts: Covenant (Disc 2) | PS2 | 1.00 | Original | | SLUS 21044 | |
| Shadow Hearts: From the New World | PS2 | 1.01 | Original | | SLUS 21326 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SLUS-00468 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SLUS-00718 | |
| Shadow Man | PC | | Original | | | |
| Shadow Man | PSX | | Original | | SLUS-00895 | |
| Shadow Man | DC | 1.001 | Original | | T-8106N | |
| Shadow Man | DC | 1.010 | Original | | T-8106N | |
| Shadow Man: 2econd Coming | PS2 | 1.03 | Original | | SLUS-20413 | |
| Shadow Master | PSX | | Original | | SLUS-00545 | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Shadow of Destiny | PSP | 1.00 | Original | | ULUS-10459 | |
| Shadow of Destiny | PS2 | 1.10 | Original | | SLUS-20146 | |
| Shadow of Rome | PS2 | 1.03 | Original | | SLUS 20902 | |
| Shadow of the Beast | PCE | | Original | | TGXCD1018 | |
| Shadow of the Beast II | MCD | | Original | | T-113045 | |
| Shadow of the Colossus | PS2 | 1.00 | Original, Greatest Hits | | SCUS 97472 | |
| Shadow Ops: Red Mercury | XBOX | | Original | | IG-037 | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Rerelease | | | |
| Shadow President Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadow the Hedgehog | XBOX | | Original | | SE-134 | |
| Shadow the Hedgehog | GC | | Original | | DL-DOL-GUPE-USA | |
| Shadow the Hedgehog | PS2 | 1.02 | Original, Greatest Hits | | SLUS 21261 … | |
| Shadow Tower | PSX | | Original | | SLUS-00863 | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Special Edition | | 04-12884CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow Watch | PC | 1.0 | Original | | | |
| Shadow Wolf Mysteries: Curse of the Full Moon / Bane of the Family | PC | | | | 33425010US | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| Shadowbane | PC | 1.0 | Original | | 650478-CD | |
| Shadowbane: The Rise of Chaos | PC | | Original | | 651727-CD | |
| ShadowCaster | PC | | CD-ROM Classics, Electronic Arts Presents | | 5393 | |
| ShadowCaster | PC | | Top Ten Pak II | | 5454 | |
| ShadowGate Classic | PPC | 1.0.0.4 | Original | | 5053626 | |
| Shadowgrounds (Disc 1) | PC | 1.01 | Original | | 000046-CD1 | |
| Shadowgrounds (Disc 2) | PC | 1.01 | Original | | 000046-CD2 | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| Shadowlands | PC | | Megapak 2 | | | |
| Shadowrun | XBOX360 | | Original | | MS-2006 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Shadowrun Chronicles: Boston Lockdown | PC | 12.0.10093 | Cosmi | | DVDC6251 | |
| Shadowrun Returns (Game Disc) | PC | | Original | | | |
| Shadows of Cairn | PC | | Rerelease | | | |
| Shadows of Cairn | PC | 1.0.022 | Rerelease | | ROM-53337 | |
| Shakedown: Hawaii | PS3 | 01.01 | Original | | BLUS-31622 | |
| Shakii the Wolf | PC | | Original | | | |
| Shanghai Double Pack | PC | | Original | | | |
| Shanghai II: Dragon's Eye | PC | 1.05 | 2 for 1 | | CDD-3044-101-U3 | |
| Shanghai: Double Pack | MAC | | Original | | 1000029-102-U3 | |
| Shanghai: Great Moments | PC | 2.00 | Bundle Version Canon OEM | | | |
| Shanghai: Triple-Threat | 3DO | | Original | | | |
| Shanghai: Triple-Threat | 3DO | | 3DO Action Pak | | | |
| Shanghai: Triple-Threat | SS | 1.002 | Original | | T-13001H | |
| Shanghai: True Valor | PSX | | Original | | SLUS-00795 | |
| Shannara | PC | 1.0.0 | Original | | | |
| Shannara | PC | 1.0 | Original | | | |
| Shannara | PC | 1.0 | Rerelease | | 7-81055-33802-6 | |
| Shape Shifter | PCE | | Original | | TGXCD1021 | |
| Shape Shifter | PC | | Original | | | |
| Shattered Steel | PC | 1.0 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.00 | Original | | CD-ICD-201-0 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-1 | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Shattered Suns | PC | 1.0 | Original | | Part # CCS00003-1 | |
| Shattered Union | XBOX | | Original | | TT-131 | |
| Shaun Palmer's Pro Snowboarder | PS2 | 1.00 | Original | | SLUS-20199 | |
| Shaun White Skateboarding | XBOX360 | | Original | | US-2095 | |
| Shaun White Skateboarding | WII | | Original | | RVL-SHNE-USA-B0 | |
| Shaun White Skateboarding | PS3 | 01.02 | Original | | BLUS-30303 | |
| Shaun White Snowboarding | XBOX360 | | Target Limited Edition | | US-2078 | |
| Shaun White Snowboarding | PS3 | 01.01 | Target Limited Edition | | BLUS-30233 | |
| Shaun White Snowboarding | PS3 | 01.01 | Original | | BLUS-30223 | |
| Shaun White Snowboarding | PS2 | 1.01 | Original | | SLUS 21853 | |
| Shaun White Snowboarding | PSP | 1.01 | Original | | ULUS 10399 | |
| Shaun White Snowboarding: Road Trip | WII | | Target Limited Edition | | RVL-RW7E-USA | |
| Shaun White Snowboarding: Road Trip | WII | | Original | | RVL-RDFE-USA | |
| Shaun White Snowboarding: World Stage | WII | | Original | | RVL-R6NE-USA-B0 | |
| Shawn Johnson Gymnastics | WII | | Original | | RVL-SJVE-USA-B0 | |
| Sheep | PSX | | Original | | SLUS-01298 | |
| Sheep | PC | 1.00.000 | Original | | | |
| Shellshock | PSX | | Original | | SLUS-00031 | |
| Shellshock | SS | 1.000 | Original | | T-7901H | |
| ShellShock 2: Blood Trails | PS3 | 01.01 | Original | | BLUS-30225 | |
| ShellShock 2: Blood Trails | PC | 1.0 | Original | | 5000026211 | |
| ShellShock: Nam '67 | PC | 1.00 | Original | | MSHOCPUS01 | |
| ShellShock: Nam '67 | PS2 | 2.00 | Original | | SLUS-20828 | |
| Shenmue (Disc 1) | DC | 1.003 | Original, Limited Edition | | 51059, 51131 | |
| Shenmue (Disc 2) | DC | 1.003 | Original | | 51059 | |
| Shenmue (Disc 3) | DC | 1.003 | Original | | 51059 | |
| Shenmue II | XBOX | | Original | | MS-050 | |
| Shepherd's Crossing | PS2 | 1.00 | Original | | SLUS 21798 | |
| Shepherd's Crossing | PSP | 1.00 | Original | | ULUS-10499 | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Collector's Edition | | 33369101US | |
| Sherlock Holmes Chronicles | PC | 1.0 | Original | | DVD732CD | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | PC | | Original | | | |
| Sherlock Holmes Versus Jack the Ripper Sherlock Holmes vs. Jack the Ripper | XBOX360 | | Original | | JW-2003 | |
| Sherlock Holmes: Consulting Detective | PCE | | Original | | TGXCD1011 | |
| Sherlock Holmes: Consulting Detective | MCD | | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | T-4501 | |
| Sherlock Holmes: Consulting Detective: Vol. I | VIS | | Original | | 25-6183 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Rerelease | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. I Sherlock Holmes: Consulting Detective: Vol. 1 | PC | | 5 ft. 10 PAK Vol. 2 | | | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | | Original | | CDRM1011460 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 5.1 | 5 ft. 10 PAK Vol. 2 | | CD 7012 SPI | |
| Sherlock Holmes: Consulting Detective: Vol. II | VIS | | Original | | 25-6184 | |
| Sherlock Holmes: Consulting Detective: Vol. II | PCE | | Original | | TGXCD1039 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 2) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. III | MAC | 3.0 | | | CDRM 835400 | |
| Sherlock Holmes: Consulting Detective: Vol. III | PC | 4 | Original | | CDRM1061930 | |
| Sherlock Holmes: Crimes & Punishments | XBOX360 | | Original | | FE-2015 | |
| Sherlock Holmes: Crimes & Punishments | PS3 | 01.01 | Original | | BLUS-31412 | |
| Sherlock Holmes: Nemesis (Disc 1) | PC | 1.00.0777 | Original | | PCO589CD1, SNY 1.0 | |
| Sherlock Holmes: Nemesis (Disc 2) | PC | 1.00.0777 | Original | | PCO589CD2, SNY 1.0 | |
| Sherlock Holmes: The Awakened | PC | 3.0 | Original | | Art. Number PF0903/US2 | |
| The Shield: The Game | PC | 1.0.0.0 | | | 11451-1DDA | |
| The Shield: The Game | PS2 | 1.01 | Original | | SLUS 21040 | |
| Shift 2: Unleashed | PC | | Limited Edition | | 1948307 | |
| Shift 2: Unleashed | PS3 | 01.00 | Limited Edition | | BLUS-30580 … | |
| Shifters | PS2 | 1.02 | Original | | SLUS 20271 | |
| Shimano Xtreme Fishing | WII | | Original | | RVL-R39E-USA-B0 | |
| Shin Megami Tensei: Devil Summoner 2: Raidou Kuzunoha vs. King Abaddon | PS2 | 1.00 | Original, Raiho Special Edition | | SLUS 21845 … | |
| Shin Megami Tensei: Devil Summoner: Raidou Kuzunoha vs. the Soulless Army | PS2 | 1.00 | Original | | SLUS-21431 | |
| Shin Megami Tensei: Digital Devil Saga | PS2 | 1.00 | Original | | SLUS 20974 | |
| Shin Megami Tensei: Digital Devil Saga 2 | PS2 | 1.00 | Original | | SLUS 21152 | |
| Shin Megami Tensei: Nocturne | PS2 | 1.01 | Original | | SLUS 20911 | |
| Shin Megami Tensei: Persona | PSP | 1.00 | Original | | ULUS-10432 | |
| Shin Megami Tensei: Persona 2: Innocent Sin | PSP | 1.00 | Original | | ULUS-10584 | |
| Shin Megami Tensei: Persona 3 | PS2 | 1.00 | Original | | SLUS 21569 | |
| Shin Megami Tensei: Persona 3 FES | PS2 | 1.00 | Original | | SLUS 21621 | |
| Shin Megami Tensei: Persona 3 Portable | PSP | 1.00 | Original | | ULUS-10512 | |
| Shin Megami Tensei: Persona 4 | PS2 | 1.00 | Original | | SLUS 21782 … | |
| Shining Force CD | MCD | | Original | | 4656 | |
| Shining Force CD | MCD | | Original | | 4656 | |
| Shining Force EXA | PS2 | 1.00 | Original | | SLUS-21567 | |
| Shining Force III | SS | 1.001 | Original | | 81383 | |
| Shining Force Neo | PS2 | 1.00 | Original | | SLUS-21206 | |
| Shining Tears | PS2 | 1.00 | Original | | SLUS-21063 | |
| Shining the Holy Ark | SS | 1.003 | Original | | 81306 | |
| Shining Wisdom | SS | 1.000 | Original, Sample | | T-12702H | |
| Shinobi | PS2 | 1.00 | Original | | SLUS 20459 | |
| Shinobi Legions | SS | 1.000 | Original | | T-2301H | |
| The Ship | PC | | Original | | | |
| Shipwreckers! | PSX | | Original | | SLUS-00558 | |
| Shiren the Wanderer | WII | | Original | | RVL-RFSE-USA-B0 | |
| Shivers | PC | 1.02 | Rerelease | | | |
| Shivers | PC | 1.02 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.0.0.2 | Rerelease | | | |
| Shivers Two: Harvest of Souls (Disc 1) | PC | 1.00 | | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | | Original | | 831744330/S174150 | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original, Rerelease | | | |
| Shivers Two: Harvest of Souls (Disc 2) | PC | 1.0.0.2 | Original | | | |
| Shock Wave | 3DO | RE1 | Original, Demo Disc (3DO Demo Disc Program) | | 7222 | |
| Shock Wave | 3DO | RE2 | Original, Not for Resale | | | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Shockwave Assault | SS | 1.000 | Original | | T-5005H | |
| Shockwave Assault (Disc 1) (Shockwave: Invasion Earth) | PSX | | Original | | SLUS-00028 | |
| Shockwave Assault (Disc 2) (Shockwave: Operation Jumpgate) | PSX | | Original | | SLUS-00137 | |
| Shogo: Mobile Armor Division 昇剛 | PC | 1.0 | Original | | | |
| Shogo: Mobile Armor Division | PC | 2.2 | Bundle Version Creative Labs OEM | | 1713310341 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Dual Jewel | | CD-C95-1298-0 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Interplay Rerelease | | CD-C95-1141-0 | |
| Shogun: Total War (Disc 1) | PC | | Rerelease | | 798727 | |
| Shogun: Total War (Disc 1) | PC | 1.0 | Original | | 798707 | |
| Shogun: Total War (Disc 2) | PC | | Original | | 798717, 1224617 | |
| Shogun: Total War: Gold Edition | PC | 1.00 | Total War: Eras | | SYX26218GM1 | |
| Shogun: Total War: Warlord Edition (Disc 1) | PC | 1.00 | Original | | 1430707 | |
| Shogun: Total War: Warlord Edition (Disc 2) | PC | 1.00 | Original | | 1430717 | |
| Shonen Jump One Piece: Unlimited Adventure | WII | | Original | | RVL-RIPE-USA | |
| Shonen Jump's One Piece: Grand Adventure | GC | | Original | | DL-DOL-GOQE-USA | |
| Shonen Jump's One Piece: Grand Adventure | PS2 | 1.01 | Original | | SLUS 21435 | |
| Shonen Jump's One Piece: Grand Battle | GC | | Original | | DL-DOL-GOPE-USA | |
| Shonen Jump's One Piece: Grand Battle | PS2 | 1.00 | Original | | SLUS 20975 | |
| Shonen Jump's One Piece: Pirates' Carnival | GC | | Original | | DL-DOL-GIPE-USA | |
| Shonen Jump's One Piece: Pirates' Carnival | PS2 | 1.00 | Original | | SLUS-21364 | |
| Shonen Jump's Shaman King: Power of Spirit | PS2 | 1.00 | Original | | SLUS-20953 | |
| The Shoot | PS3 | 01.00 | Original | | BCUS-98222 | |
| Shooting Gallery | PALM | | Original | | | |
| Shopmania | PC | | Original | | P/N 61227-CD | |
| Short Track Racing: Trading Paint | PS2 | 1.00 | Original | | SLUS 21857 | |
| Showdown: Legends of Wrestling | XBOX | | Original | | AC-029 | |
| Showdown: Legends of Wrestling | PS2 | 1.01 | Original | | SLUS-21017 | |
| Showtime Championship Boxing | WII | | Original | | RVL-RSYE-USA | |
| Shox | PS2 | 1.00 | Original | | SLUS-20533 | |
| Shrek | XBOX | | Original | | TM-001 | |
| Shrek 2 | MAC | | Original | | 10700-1CDA | |
| Shrek 2 | PC | | Original | | 32585.101.US | |
| Shrek 2 | PC | | | | 32585.101.US | |
| Shrek 2 | GC | | Original, Player's Choice | | DL-DOL-G3RE-USA, DL-DOL-G3RE-USA-02 | |
| Shrek 2 | PS2 | 1.02 | Original, Greatest Hits | | SLUS 20745 … | |
| Shrek 2: Team Action | PC | 1.0 | Original | | 32789.101.US | |
| Shrek Extra Large | GC | | Original | | DL-DOL-GS9E-USA | |
| Shrek Game Land Activity Center | PC | | Original | | 32053.101.US | |
| Shrek Super Party | XBOX | | Original | | TM-004 | |
| Shrek Super Party | GC | | Original | | DL-DOL-GSYE-USA | |
| Shrek Super Party | PS2 | 1.00 | Original | | SLUS 20516 | |
| Shrek the Third: The Search for Arthur | VFLASH | | Original | | 093140(US) | |
| Shrek Treasure Hunt | PSX | | Original | | SLUS-01463 | |
| Shrine Circus Tycoon | PC | | | | 31933.101.US | |
| Shutter Island: The Adventure Game | PC | 1.0.0 | Original | | | |
| Sid Meier's Alien Crossfire | PC | | Original | | 1405807 | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | 105907 | |
| Sid Meier's Alpha Centauri | PC | 1.0I | CD-ROM Classics | | | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | | Linux | | | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Sid Meier's Civilization Chronicles (Disc 1) | PC | | Original | | 31074-1.1 | |
| Sid Meier's Civilization Chronicles (Disc 2) | PC | | Original | | 31074-1.2 | |
| Sid Meier's Civilization II | MAC | 1.0 | Original | | P/N 7327A | |
| Sid Meier's Civilization II | PC | 1.0 | Original | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42 | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Risk: Gold Edition | | Product # 99227 | |
| Sid Meier's Civilization II | PC | 2.42a | Infogrames Rerelease | | | |
| Sid Meier's Civilization II | PC | 2.42a | Hasbro Rerelease | | Product # 99227 | |
| Sid Meier's Civilization III | PC | 1.07f | Small Box Release | | BIPCIV3CDRV1 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition | | Part # 24356CD1 | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition (Rerelease) | | | |
| Sid Meier's Civilization III | PC | 1.29f | Scholastic | | P/N CDR9640733 | |
| Sid Meier's Civilization III Complete | MAC | 1.22 | Original | | 11180-1DDA | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.3 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Original | | 25766CD1 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | Original | | 25766CD2 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | Original | | 25766CD3 | |
| Sid Meier's Civilization IV | MAC | 1.61 | Original | | 11250-1DDA | |
| Sid Meier's Civilization IV (Disc 3 & Manual) | PC | 1.61 | Game of the Year Edition | | 21712-1.3D | |
| Sid Meier's Civilization IV (Disc 1) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.6 | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 1) | PC | 1.61 | Game of the Year Edition | | 77875-1.1REA | |
| Sid Meier's Civilization IV (Disc 2) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.7 | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 2) | PC | 1.61 | Game of the Year Edition | | 77875-1.2REA | |
| Sid Meier's Civilization IV: Beyond the Sword | MAC | | Original | | 12090-1DDA | |
| Sid Meier's Civilization IV: Colonization | PC | | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Colonization | PC | 1.0.0.0 (109295) | Original | | 31491-1 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 1) | PC | 1.7.4.0 | Original | | 31183-1.1 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 2) | PC | 1.7.4.0 | Original | | 31183-1.2 | |
| Sid Meier's Civilization IV: Gold Edition (Disc 3) | PC | 1.7.4.0 | Original | | 31183-1.3 | |
| Sid Meier's Civilization IV: The Complete Edition | PC | 1.0.0.0 (109295) FINAL RELEASE | Original | | 31571-1 | |
| Sid Meier's Civilization Revolution | XBOX360 | | Original | | TT-2021 | |
| Sid Meier's Civilization Revolution | PS3 | 01.01 | Original | | BLUS-30130 | |
| Sid Meier's Civilization V | PC | | Original, Special Edition | | 31817-1 | |
| Sid Meier's Civilization V | MAC | | Original | | 12350-1DDA | |
| Sid Meier's Civilization V: Gold Edition | PC | | Original | | 41252-1 | |
| Sid Meier's Civilization VI | PC | | Original | | 41829-1 | |
| Sid Meier's Civilization: Beyond Earth | PC | | Original | | 41403-1 | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Sid Meier's Gettysburg! | PC | | CD-ROM Classics | | 1187707 | |
| Sid Meier's Gettysburg! | PC | 1.0 | Original | | 1015007 | |
| Sid Meier's Pirates! | WII | | Original | | RVL-SIDE-USA-B0 | |
| Sid Meier's Pirates! | PSP | 1.02 | Original | | ULUS-10224 | |
| Sid Meier's Pirates! (Disc 1) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 1) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD1 | |
| Sid Meier's Pirates! (Disc 2) | PC | | Rerelease | | | |
| Sid Meier's Pirates! (Disc 2) | PC | 1.0.0.0 (16296) | Original | | Part # 24810CD2 | |
| Sid Meier's Railroad Tycoon | PC | 455.03 | RomZōn! | | 0-447-40-101 | |
| Sid Meier's SimGolf | PC | 1.01 | EA Classics | | CD 796 | |
| Sid Meier's SimGolf | PC | | Rerelease | | 1641547 | |
| Sid Meier's SimGolf | PC | 1.0 | Sim Mania 2 | | 1277387 | |
| Sid Meier's SimGolf | PC | 1.01 | Rerelease | | 1434917 | |
| Siege | PC | 1.2 | | | | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| Siege of Avalon Anthology | PC | 1.7.1.0913 | Rerelease | | | |
| Sierra Pro Pilot (Disc 1) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot (Disc 2) | PC | 1.0 | Original | | | |
| Sierra Pro Pilot 98 | PC | 1.0 | Original | | | |
| Silent Bomber | PSX | | Original | | SLUS-00902 | |
| Silent Heroes: Elite Troops of WWII | PC | 1.0.29.0 | Original | | | |
| Silent Hill | PSX | | Original, Greatest Hits | | SLUS-00707 … | |
| Silent Hill 2 | PS2 | 1.20 | Original | | SLUS 20228 | |
| Silent Hill 2 | PS2 | 2.01 | Greatest Hits | | SLUS 20228 … | |
| Silent Hill 2 (Disc 1) | PC | 1.0 | Original | | Part Number 23429/23435-1 | |
| Silent Hill 2 (Disc 2) | PC | 1.0 | Original | | Part Number 23429/23435-2 | |
| Silent Hill 2 (Disc 3) | PC | 1.0 | Original | | Part Number 23429/23435-3 | |
| Silent Hill 2: Restless Dreams | XBOX | | Platinum Hits | | KN-004 | |
| Silent Hill 3 | PS2 | 1.02 | Original | | SLUS 20622 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | S2344310 | |
| Silent Hill 3 (Disc 1) | PC | 1.0.0.1 | Original | | | |
| Silent Hill 3 (Disc 2) | PC | 1.0.0.1 | Original | | S2344320 | |
| Silent Hill 3 (Disc 3) | PC | 1.0.0.1 | Original | | S2344330 | |
| Silent Hill 3 (Disc 4) | PC | 1.0.0.1 | Original | | S2344340 | |
| Silent Hill 3 (Disc 5) | PC | 1.0.0.1 | Original | | S2344350 | |
| Silent Hill 4: The Room | XBOX | | Original | | KN-031 | |