Region | Title | System | Version | Edition | Languages | Serial | Status |
| Sakura Taisen 3: Paris wa Moeteiru ka: Desktop Accessories サクラ大戦3 ~巴里は燃えているか~ デスクトップアクセサリーズ | PC | | Tokubetsu Genteiban B | | DWWWC-50121~50123 | |
| Shoujo Yoshitsune-den 少女義経伝 | PS2 | 1.01 | Tokubetsu-ban | | SLPM 65363 | |
| Shoujo Yoshitsune-den Ni: Toki o Koeru Chigiri 少女義経伝弐~刻を超える契り~ | PS2 | 1.02 | Tokubetsu-ban | | SLPM 65988 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.001 | Tokubetsu-ban (Standalone, Bundled with Mogitate SegaSaturn Vol. 2) | | 610-6864 | |
| Starsiege (Disc 1) | PC | | TOP Games Volume 2 | | Art.-Nr.: 4406 | |
| Starsiege (Disc 2) | PC | | TOP Games Volume 2 | | Art.-Nr.: 4406 | |
| Das Schwarze Auge: Die Schicksalsklinge | PC | 3.02 | TopWare | | SPI 030 | |
| Das Schwarze Auge: Sternenschweif (Disc 1) | PC | C1.02 | TopWare | | SPI 031 | |
| Das Schwarze Auge: Sternenschweif (Disc 2) | PC | C1.02 | TopWare | | SPI 031 | |
| SpaceHaste 2 SpaceHaste | PC | 1.32 | TopWare Just 4Fun | | | |
| Super Taxi Driver | PC | | TopWare Just 4Fun | | | |
| SimCity 2000 | PC | | Total Heaven 1 | | | |
| Shogun: Total War: Gold Edition | PC | 1.00 | Total War: Eras | | SYX26218GM1 | |
| Samurai Western | PS2 | 1.00 | Trade Demo | | SLUS-28051 | |
| Silent Hill | PSX | | Trade Demo | | SLUS-80707 | |
| Star Wars: Episode I: The Phantom Menace | PSX | | Trade Demo | | SLUS-80884 | |
| Star Wars: Jedi Starfighter | PS2 | 1.00 | Trade Demo | | SLUS - 280 … | |
| State of Emergency 2 | PS2 | 1.00 | Trade Demo | | SLUS-28056 | |
| Sangokushi 13 Power-Up Kit 三國志13 パワーアップキット | PC | | Treasure Box | | KTGS-00550 | |
| Sengoku Musou 2 & Sengoku Musou 2: Empires Saikyou Data [戦国無双2]&[戦国無双2Empires]最強データ | PS2 | 1.00 | Treasure Box, Sengoku Musou 2 Super Premium Pack | | SLPM 62768 | |
| Suguri スグリ | PC | 2005 8 / 9 | Trial Edition | | | |
| Silent Hill サイレントヒル | PSX | | Trial Version | | SLPM 80363 | |
| Sonic Adventure | DC | 1.000 | Trial Version for E3 | | HDR-0001 | |
| Stray Sheep: The Adventure of Poe & Merry ストレイシープポーとメリーの大冒険 | PSX | Rev 1 | Triple Pleasures, Reprint | | SLPM 86547 … | |
| Shin Megami Tensei III: Nocturne 真・女神転生Ⅲ-NOCTURNE | PS2 | 1.00 | Tsutaya Original Version | | SLPM 65259 | |
| Strike Commander / Wing Commander: Privateer | PC | | Twin Pack | | R8845CXD | |
| Sniper: Ghost Warrior スナイパー ゴーストウォリアー | PS3 | 01.01 | Ubi the Best | | BLJM 60479 | |
| Scrabble Interactive: 2007 Edition | PC | 1.1.0 | Ubisoft eXclusive / Focus Essential | | ESS760 | |
| The Settlers: Heritage of Kings | PC | 1.03.0190 | Ubisoft eXclusive / Focus Essential, The Settlers: Heritage of Kings / CSI: Crime Scene Investigation / Rayman 3: Hoodlum Havoc | | 5003950, ESS626 | |
| Spaceship Warlock | PC | 1.1.3 "MPC" | Ultimate Game Collection | | | |
| Super Game Pak | PALM | | Ultimate Game Collection, Cosmi | | PDA102501, PDA634D1 | |
| Superbike World Championship | PC | 0.1.0.24 | Ultimate Motorcycle Series | | 799607 | |
| Star Ruler | PC | 1.2.1.2 | Ultimate Sci-Fi Collection | | | |
| Starpoint Gemini | PC | 1.012 | Ultimate Sci-Fi Collection | | | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | MKW-031 | |
| Sega Rally Championship PC セガラリー・チャンピオンシップ | PC | | Ultra 2000/Ultra Series | | | |
| Shin Samurai Spirits: Haoumaru Jigokuhen 真サムライ・スピリッツ ~覇王丸地獄変~ | PC | | Ultra 2000/Ultra Series | | MKW-266 | |
| Sky Target: Daredevil Air Force スカイ・ターゲット | PC | 1.0.06.19 us | Ultra 2000/Ultra Series | | MKW-175 | |
| Sonic the Hedgehog CD ソニック・ザ・ヘッジホッグCD | PC | 1.001 | Ultra 2000/Ultra Series | | MKW-160 | |
| Sorcerian Forever ソーサリアン・フォーエバー | PC | | Ultra 2000/Ultra Series | | MKW-274 | |
| Sudden Strike Forever サドン・ストライク ~フォーエバー~ | PC | 1.0.0.1 | Ultra 2000/Ultra Series | | MKW-307 | |
| Sunsoft Classic Games 1 サンソフト クラシック ゲームズ1 | PC | | Ultra 2000/Ultra Series | | MKW-190 | |
| Sunsoft Classic Games 2 サンソフト クラシック ゲームズ2 | PC | | Ultra 2000/Ultra Series | | MKW-191 | |
| Super Air Combat スーパーエアーコンバット 蒼空の覇者 | PC | | Ultra 2000/Ultra Series | | MKW-158 | |
| Satazius Next サタゼウスネクスト | DC | 1.000 | Unlicensed | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 1) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| Sbornik e'roticheskix igr: Special'naya redakciya (Disc 2) Сборник эротических игр: Специальная редакция | PSX | | Unlicensed | | | |
| SD Media Launcher for GameCube / Wii SDメディアランチャー Wii用/GC用 | GC | | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.2 | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.23 | Unlicensed | | | |
| SharkPort: Code and Save Transfer Kit | PS2 | 2.21 | Unlicensed | | | |
| Shiawase Usagi II: Toraware Usagi Sailor Z しあわせうさぎⅡ とらわれうさぎセーラーZ | PCE | | Unlicensed | | | |
| Shiawase Usagi: Nureta Bishoujo: Hajimete Nanoni... しあわせうさぎ ~濡れた美少女‐初めてなのに…~ | PCE | | Unlicensed | | | |
| Sonic MegaMix | MCD | | Unlicensed | | | |
| Space Ranger | CDI | | Unlicensed | | OGCDI-1180 | |
| Spielbare Cheats Volume 16 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 17 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 18 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 19 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 20 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 21 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 22 | PS2 | 1.00 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 23 | PS2 | 1.10 (European) | Unlicensed | | | |
| Spielbare Cheats Volume 24 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 25 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 26 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Spielbare Cheats Volume 27 | PS2 | 1.00 beta (European) | Unlicensed | | | |
| Star Strike | MCD | | Unlicensed | | | |
| StationMaster 2/2001 Xploder Playnation Xploder Blaze | PSX | | Unlicensed | | | |
| StationMaster 4/2001 Xploder | PSX | | Unlicensed | | | |
| Striptiz-klub Golodnaya Koshka predstavlyaet Okean Strastej...: Miss Osen' Стриптиз-клуб Голодная Кошка представляет Океан Страстей...: Мисс Осень | PSX | | Unlicensed | | | |
| Super Game Converter | DC | 1.000 | Unlicensed | | | |
| Super Strike Trilogy | MCD | | Unlicensed | | | |
| Swap Magic | PS2 | 1.12 | Unlicensed | | | |
| Swap Magic 3 | PS2 | 3.10 (American) | Unlicensed | | | |
| Swap Magic 3 Plus | PS2 | 1.00 | Unlicensed | | | |
| Swap Magic 3 Plus | PS2 | 1.12 | Unlicensed | | | |
| Saucer Wars | AJCD | | Unlicensed (CD-R) | | | |
| Super Golden Brain 超級金頭腦 | PSX | | Unlicensed (Demo) | | | |
| Sturmwind | DC | 1.0 | Unlicensed (Rerelease) | | | |
| Shibai Michi しばいみち | PS2 | 1.00 | USB Mic Doukonban | | SCPS 11029 | |
| Sangokushi Eiketsuden 三國志英傑伝 | PC | 1.0 | Value Set Series | | KN10-82105 | |
| Sangokushi Koumeiden 三國志孔明伝 | PC | 1.0 | Value Set Series | | KN11-15101 | |
| Stronghold: Emperor no Yousai ストロングホールド ~皇帝の要塞~ | FMT | | Ving Marty Taiou Vol. 8 | | HMF-133 | |
| Splatterhouse スプラッターハウス | FMT | | Ving Vol. 13 | | HMD-146 | |
| Shiji Diguo III (Disc 1) (Anzhuang Guangdie) 世紀帝國Ⅲ | PC | 1.12 | Wanquanban | | 0812 Part No. X18-45747-01 | |
| Shadow Man | PC | | Wanted Games | | CD194141.00-EUR | |
| Sports Illustrated Kids: Baseball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Basketball | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Skateboarding | PC | | Wendy's Kids' Meal | | | |
| Sports Illustrated Kids: Soccer | PC | | Wendy's Kids' Meal | | | |
| Sid Meier's Civilization III 文明帝國Ⅲ | PC | 1.07f | Wenming Diguo III Jingdian Quanji | | | |
| Sid Meier's Civilization III: Conquests 文明帝國Ⅲ:一統天下 | PC | 1.00 | Wenming Diguo III Jingdian Quanji | | | |
| SimCity Enhanced CD-ROM | PC | | White Label | | | |
| Star Wars: Rebel Assault | PC | 1.7 | White Label, Rerelease | | 632630, CDRM1151470, CDRS1151470 | |
| Star Trek: 25th Anniversary Enhanced CD-ROM Star Trek: 25th Anniversary | PC | | White Label, White Label: Doubles, Star Trek: Federation Compilation | | CD-ICD-301-0 | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| SimCity 2000: CD Collection | PC | 1.00 | Windows 95 | | 0026-000-0601-A | |
| SOCOM: Confrontation ソーコム:コンフロンテーション | PS3 | 01.00 | Wireless Headset Bundle | | BCJS 30024 | |
| Sangokushi II 三國志Ⅱ | FMT | | with Soundware | | HMB-159 | |
| Sangokushi III 三國志Ⅲ | FMT | | with Soundware | | HMD-131 | |
| Sangokushi IV 三國志Ⅳ | FMT | | with Soundware | | HMF-139 | |
| Suikoden: Tenmei no Chikai 水滸伝・天命の誓い | FMT | | with Soundware | | HMB-108 | |
| Szalony Kurczak i Tajemniczy Zamek | PC | | wkiosku | | | |
| Szalony Kurczak w Dżungli | PC | | wkiosku | | | |
| SkyMaze X3D SkyMaze | PC | | X3D | | | |
| Speed Thief X3D Speed Thief | PC | | X3D | | | |
| Street Fighter IV: The Ties That Bind (Bonus Disc) | XBOX360 | | Xbox 360 Game Bundle | | CC-2033 | |
| Shanghai: Second Dynasty | PC | | Xplosiv | | EI-1588 ENGLISH | |
| Sheep | PC | 1.0.0.1 | Xplosiv | | EI-1381 | |
| Skateboard Park Tycoon World Tour 2003 | PC | 1.0.0.1 | Xplosiv | | XP-2118 EUROPEAN | |
| Sonic & Knuckles Collection | PC | | Xplosiv | | XP-1859 EUROPEAN, XP-1891, XP-1891 EUROPEAN | |
| Sonic 3D: Flickies' Island | PC | | Xplosiv | | XP-1304 | |
| Sonic 3D: Flickies' Island | PC | | Xplosiv | | XP-1304 | |
| Sonic R | PC | | Xplosiv | | XP-1263 | |
| Sonic R | PC | | Xplosiv | | EI-1530 EUROPEAN | |
| Space Invaders | PC | 1.1 | Xplosiv | | XP-1867 EUROPEAN | |
| Space Invaders Anniversary | PC | | Xplosiv | | XP-1879 | |
| Supercar Street Challenge | PC | | Xplosiv | | EI-1477 EUROPEAN | |
| SiN | PC | | Xplosiv (Covermount) | | | |
| Secret Game: Killer Queen: Portable シークレットゲーム -KILLER QUEEN- PORTABLE | PSP | 1.01 | Yeti Best | | ULJM 05953 | |
| Soul Eater: Battle Resonance: Tamashii Kyoumei Disc ソウルイーター バトルレゾナンス 魂共鳴ディスク | PC | | Yoyaku Tokuten | | | |
| Suzumiya Haruhi no Tomadoi: Uchuu-hatsu! Full CG: Odoru SOS-dan (Chou Eizou-ban) 涼宮ハルヒの戸惑 宇宙初!フルCG 「踊るSOS団」 | PS2 | 1.01 | Yoyaku Tokuten Disc | | SLPM 68020 | |
| Sheep シープ | PC | 1.0.0.1 | Yuu Yuu 1980yen | | MKY-040 | |
| Sudden Strike Forever サドンストライク ~フォーエバー~ | PC | | Yuu Yuu 1980yen | | MKY-045 | |
| Space Invaders スペースインベーダー | PC | | Yuuyuu 1,480-yen (Publishing Distribution) | | KMK-1210, MKY-055 | |
| Sekai Saikyou Ginsei Igo 2 世界最強銀星囲碁2 | PC | 3.0 | Yuuyuu 1,980-yen | | | |
| Super Shanghai: Dragon's Eye スーパー上海 ドラゴンズアイ | PC | 1.00 | Yuuyuu 1,980-yen, Ultra 2000/Ultra Series | | MKW-118, MKY-004 | |
| Shanggu Juanzhou III: Chenfeng (Disc A) 上古卷轴Ⅲ:晨风 | PC | 1.0.0417 | Zhima Kai Men | | | |
| Shanggu Juanzhou III: Chenfeng (Disc B) 上古卷轴Ⅲ:晨风 | PC | | Zhima Kai Men | | | |
| Sanguozhi IV 三國志Ⅳ | SS | 1.003 | Zhongwenban | | T-7601H-11, T-7601H-16 | |
| Sanguozhi V 三國志Ⅴ | PSX | | Zhongwenban | | SCPS 45128 | |
| Sanguozhi V 三國志Ⅴ | SS | 1.000 | Zhongwenban | | T-7606H-11, T-7606H-16 | |
| Sanguozhi Yingjiezhuan 三國志英傑伝 | SS | 1.000 | Zhongwenban | | T-7603H-11, T-7603H-16 | |
| Strike Commander | PC | | Zielona Seria | | R9615CD | |
| Sangokushi Battlefield 三國志 Battlefield | PC | | βversion | | β-17292 | |