| Region | Title | System | Version | Edition | Languages | Serial | Status |
|---|
 | SCORE International Baja 1000: The Official Game | WII | | Original |  | RVL-RJCE-USA |  |
| SCORE International Baja 1000: The Official Game | PS3 | 01.00 | Original | | BLUS-30230 | ![2 and more dumps from original media [!]](/images/status/green.png "2 and more dumps from original media [!]") |
 | SCORE International Baja 1000: World Championship Off Road Racing | WII | | Original | | RVL-RJCP-EUR-B0 | |
| SCORE International Baja 1000: World Championship Off Road Racing | PS3 | 01.00 | Original | | BLES-00421 | |
| SCORE International Baja 1000: World Championship Off Road Racing | PS2 | 1.00 | Original | | SLES-55295 | |
| The Scorpion King: Rise of the Akkadian | GC | | Original | | DL-DOL-GSKE-USA | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.03 | Original | | SLUS-20424 | |
| Scratches: Director's Cut | PC | | Rerelease | | | |
| Scribblenauts (Asset Disc) | PC | | Press Kit | | | |
 | Scribblenauts Unlimited | PC | | Original | | 2000079870, 5000145356 | |
| SD Media Launcher for GameCube / Wii | GC | | Unlicensed | | | |
| SD Media Launcher for GameCube / Wii | GC | | Unlicensed | | | |
| Sea Monsters: A Prehistoric Adventure | WII | | Original | | RVL-RC7E-USA | |
| SeaBlade | XBOX | | Original | | VU-023 | |
| Seal of Evil | PC | | Original | | 904066DVD | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZP-EUR | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLES-53804 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | GC | | Original | | DL-DOL-GJZE-USA | |
 | SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | XBOX | | Original | | AV-080 | |
| Second Sight | GC | | Original | | DL-DOL-GISE-USA | |
| Second Sight | PS2 | 1.00 | Original | | SLUS-21033 | |
| Secret Agent Clank | PSP | 1.00 | Demo | | UCUS 98707 | |
| Secret Files: Tunguska | PC | 1.03 | Original, Xplosiv | | ECD008099M 00060722-01, ECD900019D 00060810-01, XP-2221 3026412 | |
| Secret Files: Tunguska | WII | | Original | | RVL-RTUE-USA-B0 | |
| The Secret of the Silver Earring
Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| Secret Service | PS2 | 1.00 | Original | | SLES-55330 | |
| Secret Service | XBOX360 | | Original | | AV-2084 | |
| Secret Service | PC | 1.0 | Original | | 35635.101.UK, 35635.101.US | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51707 | |
| Secret Weapons over Normandy | PS2 | 1.00 | Review Build | | SLUS-20762 | |
 | Section 8: Prejudice | PS3 | 01.00 | Beta | | | |
| The Seed: Warzone | PS2 | 1.00 | Original | | SLES-51715 | |
| Seek & Find Adventures | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek & Find Adventures 5 Pack | PC | | Original | | | |
| Seek and Destroy | PS2 | 1.01 | Original | | SLUS 20606 | |
| Sega Bass Fishing | WII | | Original | | RVL-RBTE-USA, RVL-RBTE-USA-B0 | |
| Sega Bass Fishing 2 | DC | 1.080 | Original | | 51166 | |
 | Sega Classics Collection | PS2 | 1.02 | Original, Promo | | SLES-53461 … | |
| Sega Classics Collection | PS2 | 1.01 | Original | | SLUS 21009 | |
 | Sega Extreme Sports
セガ エクストリーム スポーツ | DC | 1.003 | Original | | HDR-0146 | |
| Sega Genesis Collection | PS2 | 1.01 | Original | | SLUS 21542 | |
| Sega Genesis Collection | PSP | 1.01 | Original, SEGA Fun Pack | | ULUS-10192 | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega GT Online | XBOX | | Original | | SE-033 | |
| Sega Rally Revo | PSP | 1.00 | Original | | ULUS-10311 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSP-EUR | |
| Sega Soccer Slam | XBOX | | Original | | IG-041 | |
| Sega Soccer Slam | PS2 | 1.01 | Original | | SLES-51125 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSE-USA | |
| Sega Soccer Slam | PS2 | 1.00 | Original | | SLUS-20509 | |
| Sega³ Demo | PS2 | 1.10 | | | SCED-50761 | |
| Selector Demo 03
PlayStation 2 Official Demo Disc Retail Edition 3 | PS2 | 1.00 | | | SCED-51146 | |
| Selector Demo 04
PlayStation 2 Official Demo Disc Retail Edition 4 | PS2 | 1.00 | | | SCED-51269 | |
| Selector Demo 05
Selector Demo 05 April 2003: June 2003 | PS2 | 1.00 | | | SCED-51683 | |
| Sengoku Rance
戦国ランス | PC | 1.07 | Limited Edition | | MG-AS-RE-004 | |
| Serious Sam | XBOX | | Original | | TT-004 | |
| Serious Sam 3: BFE | PC | | Original | | MTC000692-D | |
| Serious Sam: Next Encounter | PS2 | 1.01 | Original | | SLUS-20907 | |
| Serious Sam: Next Encounter | GC | Rev 1 | Original | | DL-DOL-G3BE-USA | |
 | Serious Sam: The First Encounter | PC | | | | | |
| Serious Sam: The Second Encounter | PC | | | | | |
 | Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Original | | RVL-SS4U-AUS-B0 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS4E-USA-B0 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Original | | RVL-SS3U-AUS-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | PC | | Original | | | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Learn, Play and Grow Preschool / Sesame Street: Let's Go to Preschool / Sesame Street: First Steps | PC | | Southwestern Kids' Collection | | 05SS3-R01 | |
| Sesame Street: Ready, Set, Grover! The Videogame | WII | | Original | | RVL-SESU-AUS-B0 | |
| Settlers II, The: Veni, Vidi, Vici | PC | 1.51 | Rerelease | | | |
| The Settlers III: Gold Edition (Disc 2) | PC | 1.25.0.125 | Original | | | |
| Seven Kingdoms: Conquest | PC | 1.00 | Original | | DVD580CD | |
| Seventh Cross Evolution | DC | 1.000 | Original | | T-41301N | |
| Shadow Hearts | PS2 | 1.00 | Original | | SLUS 20347 | |
 | Shadow Hearts | PS2 | 1.01 | Original | | SLES-50677 | |
| Shadow Hearts: Covenant (Disc 1) | PS2 | 1.00 | Original | | SLUS 21041 | |
| Shadow Hearts: Covenant (Disc 2) | PS2 | 1.00 | Original | | SLUS 21044 | |
| Shadow Hearts: From the New World | PS2 | 1.02 | Original, Rerelease | | SLES-54711 … | |
| Shadow Hearts: From the New World | PS2 | 1.01 | Original | | SLUS 21326 | |
| Shadow of Destiny | PSP | 1.00 | Original | | ULUS-10459 | |
| Shadow of Destiny | PS2 | 1.10 | Original | | SLUS-20146 | |
| Shadow of Ganymede | PS2 | 1.03 | Original | | SLES-53345 … | |
| Shadow of Rome | PS2 | 1.00 | Demo | | SLUS 29139 | |
| Shadow of Rome | PS2 | 1.03 | Original | | SLUS 20902 | |
| Shadow of the Beast | PCE | | Original | | TGXCD1018 | |
| Shadow of the Colossus | PS2 | 1.00 | Demo | | SCUS 97505 | |
| Shadow of the Colossus | PS2 | 1.00 | Original, Greatest Hits | | SCUS 97472 | |
| Shadow Ops: Red Mercury | XBOX | | Original | | IG-037 | |
| Shadow President
Shadow President: The Simulation of Presidential World Power! | PC | | Gold Medal 12 CD Pack | | MQ 13-004-116 | |
| Shadow Warrior | PC | Final 1.5 | Special Edition | | MTC000875-D | |
| SHADOW Warriors
シャドー・ウォリアー | 3DO | | Original | | FZ-SJ0155 | |
| Shadowgrounds | PC | 1.02 | Original | | UGL0001 | |
| Shadowgrounds | PC | | Linux (LGP) | | | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| Shadowgrounds Survivor | PC | | Linux (LGP) | | | |
| Shadowrun | PC | 1.0 | Original | | 0307 Part No. X13-37202-01 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Shakedown: Hawaii | WII | | Original | | RVL-SEVP-EUR-B0 | |
