Region | Title | System | Version | Edition | Languages | Serial | Status |
| Shaman King: Funbari Spirits シャーマンキング ~ふんばりスピリッツ~ | PS2 | 1.04 | Original | | SLPS 25359 | |
| Shallie no Atelier: Tasogare no Umi no Renkinjutsushi シャリーのアトリエ ~黄昏の海の錬金術士~ | PS3 | 01.01 | Original | | BLJM 61192 | |
| Shakugan no Shana 灼眼のシャナ | PS2 | 1.01 | Original, Dengeki SP | | SLPS 25599 … | |
| Shakedown: Hawaii | PS3 | 01.01 | Original | | BLUS-31622 | |
| Shake Kids シェイクキッズ | PSX | | Original | | SLPS 01472 | |
| Shadows of the Damned | XBOX360 | | Original | | EA-2346 | |
| Shadows of the Damned | PS3 | 01.00 | Original | | BLAS 50346 … | |
| Shadows of the Damned シャドウ オブ ザ ダムド | PS3 | 01.00 | Original, EA Best Hits | | BLJM 60358 … | |
| Shadows of the Damned | PS3 | 01.00 | Original | | BLES-01276 | |
| Shadowrun Chronicles: Boston Lockdown | PC | 12.0.10093 | Cosmi | | DVDC6251 | |
| Shadowrun | PC | 1.1.1.0 | Original | | 0307 Part No. X13-37194-01 | |
| Shadowlands | PC | | Original, 10 Pack CD-ROM Series, Action CD-ROM 5 Pak | | | |
| Shadowgrounds Survivor | PC | 1.0 | Original | | 000152 DVD | |
| ShadowCaster | PC | | Original | | | |
| ShadowCaster | PC | | CD-ROM Classics, Electronic Arts Presents | | 5393 | |
| A Shadow's Tale | WII | | Original | | RVL-SDWP-EUR-B0 | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| Shadow Watch | PC | 1.0 | Original | | | |
| SHADOW Warriors シャドー・ウォリアー | 3DO | | Original | | FZ-SJ0155 | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original | | | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Special Edition | | 04-12884CD | |
| Shadow Warrior Lo Wang is Shadow Warrior | PC | 1.2 | Original, East Meets West | | 04-12539CD | |
| Shadow Tower Abyss シャドウタワー アビス | PS2 | 1.10 | Original | | SLPS 25217 | |
| Shadow Tower | PSX | | Original | | SLPS 01420 | |
| Shadow the Hedgehog | PS2 | 1.02 | Original, Greatest Hits | | SLUS 21261 … | |
| Shadow the Hedgehog | XBOX | | Original | | SE-134 | |
| Shadow the Hedgehog | GC | | Original | | DL-DOL-GUPE-USA | |
| Shadow the Hedgehog | PS2 | 1.01 | Original, Platinum | | SLES-53542 … | |
| Shadow of the Colossus + Ico | PS2 | 1.00 | Demo | | SCED-53990 | |
| Shadow of the Colossus | PS2 | 1.00 | Demo | | SCUS 97505 | |
| Shadow of the Colossus | PS2 | 1.00 | Original, Greatest Hits | | SCUS 97472 | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | FMT | | Original | | HMC-157 | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | PCE | | Original | | JCCD2008 | |
| Shadow of the Beast II: Juushin no Jubaku シャドー・オブ・ザ・ビーストⅡ ~獣神の呪縛~ | MCD | | Original | | T-60034 | |
| Shadow of the Beast II: Juushin no Jubaku シャドー・オブ・ザ・ビーストⅡ ~獣神の呪縛~ | FMT | | Original | | HMD-184 | |
| Shadow of Rome | PS2 | 1.03 | Original | | SLUS 20902 | |
| Shadow of Rome シャドウ・オブ・ローマ | PS2 | 1.01 | Original, CapKore | | SLPM 65883 … | |
| Shadow of Rome シャドウ・オブ・ローマ | PS2 | 1.00 | Taikenban | | SLPM 61109 | |
| Shadow of Memories シャドウ オブ メモリーズ | PS2 | 1.20 | Original | | SLPM 65013 | |
| Shadow of Memories | PC | | Original | | | |
| Shadow of Destiny | PC | 1.0 | Original | | Part Number 23420 | |
| Shadow Man: 2econd Coming | PS2 | 1.04 | Original | | SLES-50446 | |
| Shadow Man | PC | | Covermount | | | |
| Shadow Man | PC | | Original | | CD194141.00-EUR | |
| Shadow Madness | PSX | | Demo | | SLUS-90031 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12099 | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02099 | |
| Shadow Hearts: From the New World | PS2 | 1.01 | Original | | SLUS 21326 | |
| Shadow Hearts: From the New World シャドウ ハーツ フロム・ザ・ニュー・ワールド | PS2 | 1.01 | Taikenban | | SLPM 60264 | |
| Shadow Hearts: From the New World シャドウ ハーツ フロム・ザ・ニュー・ワールド | PS2 | 1.01 | Original, Starter Pack | | SLPM 66071 | |
| Shadow Hearts: Covenant (Disc 2) | PS2 | 1.00 | Original | | SLUS 21044 | |
| Shadow Hearts: Covenant (Disc 1) | PS2 | 1.00 | Original | | SLUS 21041 | |
| Shadow Hearts II (Disc 2) シャドウ ハーツⅡ | PS2 | 1.02 | Gentei DX Pack | | SLPS 25318 | |
| Shadow Hearts II (Disc 2) シャドウ ハーツⅡ | PS2 | 1.02 | Original | | SLPS 25335 | |
| Shadow Hearts II (Disc 1) シャドウ ハーツⅡ | PS2 | 1.02 | Gentei DX Pack | | SLPS 25317 | |
| Shadow Hearts II (Disc 1) シャドウ ハーツⅡ | PS2 | 1.02 | Original | | SLPS 25334 | |
| Shadow Hearts II シャドウ ハーツⅡ | PS2 | 1.01 | Taikenban | | SLPM 60214 … | |
| Shadow Hearts II (Disc 2) Shadow Hearts: Covenant | PS2 | 1.02 | Original | | SLES-82031 … | |
| Shadow Hearts II (Disc 1) Shadow Hearts: Covenant | PS2 | 1.02 | Original | | SLES-82030 … | |
| Shadow Hearts | PS2 | 1.00 | Original | | SLUS 20347 | |
| Shadow Hearts シャドウ ハーツ | PS2 | 1.02 | Taikenban | | SLPM 60145 | |
| Shadow Hearts シャドウ ハーツ | PS2 | 1.02 | Original | | SLPS 25041 | |
| Shadow Fighter | CD32 | | Original | | | |
| Shadow Company: Left for Dead | PC | | Original | | | |
| Shadow and Shadow シャドウ アンド シャドウ | PSX | | Original | | SLPM 87027 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-1 | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-0 | |
| Shadoan Kingdom II: Shadoan | CDI | 1.03 | Original | | 810 0280 | |
| Shade: L'Ira degli Angeli | PC | 1.2 | EXA Games Premium, Covermount | | | |
| Shachou Eiyuuden 射鵰英雄傳 | PSX | | Original | | SCPS 10139 | |
| SGGG: Segagaga セガガガ | DC | 1.022 | First Print Limited Edition, Tsuujou-ban | | HDR-0083, HDR-0151 | |
| Sexy Parodius セクシー・パロディウス | SS | 1.040 | Original | | T-9514G | |
| Sexy Parodius セクシーパロディウス | PSX | | Original | | SLPM 86009 | |
| Sexy Idol Mahjong: Yakyuuken no Uta セクシー・アイドル麻雀 ~野球拳の詩~ | PCE | | Original | | NBCD4007 | |
| Sexy Idol Mahjong: Fashion Monogatari セクシー・アイドルま~じゃん ~ファッション物語~ | PCE | | Original | | NBCD4006 | |
| Sex | 3DO | | Original | | | |
| Sewer Shark | 3DO | | Original | | | |
| Sewer Shark | MCD | Rev 1 | Original | | T-6201 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Severance: Blade of Darkness | PC | 1.00 | Original | | PSEVCDGE00 | |
| The Seventh Seal: The Resurrection of the Dark Lord (Disc 2) 第七封印 魔神苏醒第七封印:魔神甦醒 | PC | 2.0.0.0 | Original, Limited Edition | | | |
| Seven Kingdoms: Artwork | MAC | | Art Assets | | | |
| Seven Kingdoms: Ancient Adversaries | PC | 2.00 | Original, 2in1 Pack | | | |
| Seven Kingdoms | PC | 1.0 | Original | | 04033 CD | |
| Seven Kingdoms | PC | | Play the Games Vol. 1 | | | |
| Setup Utility for DTL-H1500 (Version 1.1) | PSX | | Original | | | |
| The Settlers: Rise of an Empire: The Eastern Realm | PC | 1.4.4273 | Original | | 300011555, 300011767 | |
| The Settlers: Rise of an Empire | PC | 1.6.4287 | Covermount, Rerelease | | 300007676 | |
| The Settlers: Rise of an Empire | PC | 1.0.4140 | Original, Bundle Version LG OEM | | 300007676 | |
| The Settlers: Heritage of Kings | PC | 1.03.0190 | Ubisoft eXclusive / Focus Essential, The Settlers: Heritage of Kings / CSI: Crime Scene Investigation / Rayman 3: Hoodlum Havoc | | 5003950, ESS626 | |
| The Settlers IV: Złota Edycja | PC | 2.50.1516.0 | eXtra Klasyka Next | | | |
| The Settlers III (Disc 2) | PC | 0.0.0.91 | Original | | | |
| The Settlers II: 10th Anniversary | PC | | Original | | 5004880 | |
| The Settlers 7: Paths to a Kingdom | PC | | Original, Ubisoft Exclusive Think | | 300028951 | |
| Sesame Street: Once Upon a Monster | XBOX360 | | Original | | WR-2060 | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | 3DO | | Original | | | |
| Sesame Street: Let's Make a Word! | PC | | Original, Software for the fun of it | | KES006 | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Elmo's Number Journey | PSX | | Original, Twin Pack | | SLUS-00622 … | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original, Twin Pack | | SLUS-00621 … | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS4E-USA-B0 | |
| Sesame Street Toddler: Elmo's Art Workshop (Disc 2) | PC | 3.0 | Rerelease | | STL744AE-CD2 | |
| Sesame Street Sports | PSX | | Original | | SLUS-01180 | |
| Serious Sam: The Second Encounter Крутой Сэм: Второе пришествие | PC | 1.05 | 1C: Kollekciya igrushek | | | |
| Serious Sam: The Second Encounter | PC | 1.07 | Gold Edition, Covermount | | | |
| Serious Sam: The Second Encounter | PC | 1.05 | Original, TakeAdvantage | | | |
| Serious Sam: The First Encounter | PC | 1.02 | Bundle Version Gainward OEM | | | |
| Serious Sam: The First Encounter | PC | 1.00 | Original | | | |
| Serious Sam: The First Encounter Крутой Сэм: Первая Кровь | PC | 1.00b | 1C: Kollekciya igrushek | | | |
| Serious Sam: The First Encounter | PC | 1.05 | Gold Edition | | | |
| Serious Sam: The First Encounter 英雄萨姆 | PC | 1.00 | Original, Zhima Kai Men | | | |
| Serious Sam: Next Encounter | PS2 | 1.02 | Original | | SLES-52450 | |
| Serious Sam II | XBOX | | Original | | TT-013 | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II | PC | | Original | | | |
| Serial Experiments Lain (Disc 2) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01604 | |
| Serial Experiments Lain (Disc 1) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01603 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 2) シークエンス・パラディウム3 ~泡沫の天地~ | PC | | Original | | KGD-04061 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 1) シークエンス・パラディウム3 ~泡沫の天地~ | PC | | Original | | KGD-04060 | |
| Sequence Palladium 2: Yami no Shousei シークエンス・パラディウム2 ~闇の笑声~ | PC | 1.0 Build 1049 | Original | | KGD-9990 | |
| Sequence Palladium シークエンス パラディウム | PC | 1.0.0.1 | Original | | WIC-5952 | |
| Sequence Palladium シークエンス パラディウム | PC | | DigiCube, Media Kite Great Series | | DWRPM-00089, MKW-182 | |
| Septerra Core: Legacy of the Creator | PC | 1.02 | Dual Jewel | | CD-C95-1298-1 | |
| Septerra Core: Legacy of the Creator | PC | 1.00 | Original | | CD-W58-1103-0 | |
| Septerra Core: Legacy of the Creator | PC | | Original | | 1CSP OR03 0020 IR | |
| Septerra Core: Legacy of the Creator | PC | 1.02 | Gold Strategy Games, Rerelease | | TWI011 | |
| Separate Hearts 散碎的原色 | PC | | Original | | CV022 | |
| Sentou Kokka: Air Land Battle 戦闘国家 AIR LAND BATTLE | PSX | Rev 1 | Original, PlayStation the Best | | SCPS 10015 … | |
| Sentou Kokka Kai: Improved 戦闘国家-改- IMPROVED | PSX | | Original, PlayStation the Best | | SCPS 10034 … | |
| Sento Monogatari: Sono I 「占都物語」 そのⅠ | 3DO | | Original | | FZ-SJ4054 | |
| Sentinel Returns | PSX | | Original | | SLES-01051 | |
| Sentimental Graffiti 2: Third Window センチメンタルグラフティ2 サードウィンドウ | DC | 3.000 | Hibaihin | | 610-7749 | |
| Sentimental Graffiti (Disc 2) (Second Window) センチメンタル・グラフティ | SS | 1.000 | Original | | T-20106G | |
| Sentimental Graffiti (Disc 1) (Game Disc) センチメンタル・グラフティ | SS | 1.003 | Original | | T-20106G | |
| Sentient: Explore the Infinite | PSX | | Original, Limited Edition | | SLES-00106 | |
| Sensual Angels センシャル・エンジェル | FMT | | DCCS (FM Towns Release), PC-9821 Release | | DWDC3813 | |
| Sensible Soccer 2006 | PS2 | 1.01 | Original, Promo | | SLES-53810 | |
| Sensible Soccer | MCD | | Bundled with Magazine (Playable Demo - Mega Power Disc 5, Demo) | | | |
| Senryaku Shougi 戦略将棋 | SS | 1.000 | Original | | T-10604G | |
| El Señor de los Anillos: Las Dos Torres | PS2 | 1.00 | Original | | SLES-51256 | |
| El Señor de los Anillos: El Retorno del Rey | PS2 | 1.00 | Original, Original (Bundled with Sony PlayStation 2 Console) | | SLES-52020 | |
| Senkutsu Katsuryu Taisen: Chaos Seed (Disc 2) (Omake Disc) 仙窟活龍大戦 カオス・シード | SS | 1.003 | Original | | T-30902G | |
| Senkutsu Katsuryu Taisen: Chaos Seed (Disc 1) (Game Disc) 仙窟活龍大戦 カオス・シード | SS | 2.000 | Satakore | | T-30904G | |
| Senkou no Ronde Rev.X 旋光の輪舞 リビジョンエックス | XBOX360 | | Original, Platinum Collection | | GR-2001 | |
| Senjou no Valkyria 3: Unrecorded Chronicles 戦場のヴァルキュリア3 ~UNRECORDED ◆ CHRONICLES~ | PSP | 1.01 | Original | | ULJM 05781 | |
| Senjou no Valkyria 2: Gallia Ouritsu Shikan Gakkou 戦場のヴァルキュリア2 ガリア王立士官学校 | PSP | 1.01 | Original | | ULJM 05560 | |
| Senjou no Valkyria 戦場のヴァルキュリア | PS3 | 01.01 | Original | | BLJM 60063 | |
| Senjou no Valkyria 戦場のヴァルキュリア | PS3 | 01.00 | PlayStation 3 the Best | | BLJM 55008 | |
| Sengoku-hime: Senran ni Mau Otome-tachi 戦極姫 ~戦乱に舞う乙女達~ | PS2 | 1.01 | Original, Genteiban | | SLPM 55218 … | |
| Sengoku-hime 4: Souhahyakkei, Hana Mamoru Chikai 戦極姫4 ~争覇百計、花守る誓い~ | PS3 | 01.01 | Original, Gouka Genteiban | | BLJM 61103 … | |
| Sengoku-hime 3: Tenka o Kirisaku Hikari to Kage 戦極姫3 ~天下を切り裂く光と影~ | PS3 | 01.01 | Original, Gouka Genteiban, SystemSoft Selection | | BLJM 60555 … | |
| Sengoku Rance 戦国ランス | PC | 1.00 | Original | | ALS-0061 | |
| Sengoku Musou: Moushouden 戦国無双 ~猛将伝~ | PS2 | 1.03 | Original, PlayStation 2 the Best, PlayStation 2 the Best Reprint | | SLPM 65718 … | |
| Sengoku Musou 4 戦国無双4 | PS3 | 01.02 | Original, PlayStation 3 the Best | | BLJM 55086 … | |
| Sengoku Musou 3: Empires 戦国無双3 Empires | PS3 | 01.01 | Original | | BLAS 50364 … | |
| Sengoku Musou 3 Z 戦国無双3 Z | PS3 | 01.02 | Original | | BLJM 60313 | |
| Sengoku Musou 3 戦国無双3 | WII | Rev 1 | Original | | RVL-S59J-JPN-E0 | |
| Sengoku Musou 2: Moushouden 戦国無双2 猛将伝 | PS2 | 2.00 | Original, Treasure Box, Sengoku Musou 2 Super Premium Pack | | SLPM 67014 | |
| Sengoku Musou 2: Empires 戦国無双2 Empires | PS2 | 1.01 | Original, PlayStation 2 the Best, Sengoku Musou 2 & 2 Empires Premium Box, Sengoku Musou 2 Super Premium Pack, PlayStation 2 the Best Reprint | | SLPM 66542 … | |
| Sengoku Musou 2 & Sengoku Musou 2: Empires Saikyou Data [戦国無双2]&[戦国無双2Empires]最強データ | PS2 | 1.00 | Treasure Box, Sengoku Musou 2 Super Premium Pack | | SLPM 62768 | |
| Sengoku Musou 2 戰國無雙2、戦国無双2 | PS2 | 1.02 | Original, PlayStation 2 the Best, Sengoku Musou 2 & 2 Empires Premium Box, Sengoku Musou 2 Super Premium Pack, Sengoku Musou 2 Treasure Box | | SLAJ 25077 … | |
| Sengoku Musou 戰國無雙、戦国無双 | PS2 | 1.08 | Original, PlayStation 2 the Best, PlayStation 2 the Best Reprint, Sengoku Kouryaku Box | | SLAJ 25035 … | |
| Sengoku Kantou Sangokushi 戦国関東三国志 | PCE | | Original | | IGCD1002 | |
| Sengoku Denshou ~ Sengoku 戦国伝承 | NGCD | | Original | | NGCD-017 | |
| Sengoku Denshou 戦国伝承 | MCD | | Original | | T-24034 | |
| Sengoku Cyber: Fujimaru Jigokuhen 戦国サイバー 藤丸地獄変 | PSX | | Original | | SCPS 10011 | |
| Sengoku Cannon: Sengoku Ace Episode III 戦国キャノン SENGOKU ACE EPISODE III | PSP | 1.03 | Original, Sample | | UCAS-40019 … | |
| Sengoku Blade: Sengoku Ace Episode II (Disc 2) (Sengoku Kawaraban: Digital Edition) 戦国ブレード | SS | 1.002 | Original | | T-14410G | |
| Sengoku Basara: Samurai Heroes | PS3 | 01.00 | Original | | BLES-00832 … | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3E-USA-B0 | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3P-EUR-B0 | |
| Sengoku Basara: Chronicle Heroes 戦国BASARA クロニクルヒーローズ | PSP | 1.01 | Original | | ULJM 05903 … | |
| Sengoku Basara: Battle Heroes 戦国BASARA ~バトル・ヒーローズ~ | PSP | 1.01 | Original, PSP the Best | | ULJM 05436 … | |
| Sengoku Basara X 戦国BASARA X(クロス) | PS2 | 1.01 | Original, Genteiban | | SLKA 25435 … | |
| Sengoku Basara HD Collection 戦国BASARA HDコレクション | PS3 | 01.00 | Original | | BLJM 60488 | |
| Sengoku Basara 4: Sumeragi 戦国BASARA4 皇 | PS3 | 01.00 | Original | | BLJM 61248 | |
| Sengoku Basara 4 戦国BASARA4 | PS3 | 01.00 | Original | | BLAS 50675 … | |
| Sengoku Basara 3: Utage 戦国BASARA3 宴 | PS3 | 01.01 | Original, PlayStation 3 the Best | | BLJM 55049 … | |
| Sengoku Basara 3 戦国BASARA3 | PS3 | 01.00 | Original, PlayStation 3 the Best | | BLAS 50220 … | |
| Sengoku Basara 2: Heroes 戦国BASARA2 ~英雄外伝~ | PS2 | 1.02 | Original, PlayStation 2 the Best, PlayStation 2 the Best Reprint | | SLPM 66848 … | |
| Sengoku Basara 2 戦国BASARA2 | PS2 | 1.01 | Original, Best Price, CapKore | | SLPM 66447 … | |
| Sengoku Basara 戦国BASARA | PS2 | 1.03 | Original, Best Price, CapKore | | SLPM 66058 … | |
| Sekigahara 関ヶ原 | FMT | | Original | | HMD-128 | |
| Seiya Monogatari: Anearth Fantasy Stories 聖夜物語 | PCE | | Bundled with Book (Dengeki PC Engine Special Edition - Taikenban) | | HMD-0004 | |
| Seiryuu Densetsu: Monbit 聖竜伝説モンビット | PCE | Rev 1 | Original | | HCD1018 | |
| Seireki 1999: Pharaoh no Fukkatsu 西暦1999 ~ファラオの復活~ | PSX | | Original | | SLPS 00599 | |
| Seirei Shinseiki: Fhey Area 精霊神世紀 ~フェイエリア~ | MCD | | Original | | T-32034 | |
| Seirei Senshi Spriggan 精霊戦士スプリガン | PCE | | Original | | NXCD1004 | |
| Seima Densetsu 3x3 Eyes 聖魔伝説 3×3EYES | MCD | | Original | | G-6007, GD0004JG | |
| Seikon no Joka: Hikari to Yami no Seioujo 聖痕のジョカ ~光と闇の聖王女~ | PSX | | Original | | SLPS 00483 | |
| Seiken Densetsu: Legend of Mana 聖剣伝説 レジェンド オブ マナ | PSX | | Original, Square Millennium Collection, PSone Books, Ultimate Hits, Sample (Asia) | | SCPS 45416 … | |
| Seiken Densetsu 4 聖剣伝説4 | PS2 | 1.02 | Original | | SCKA 20101 … | |
| Le Seigneur des Anneaux: Les Deux Tours | GC | | Original | | DL-DOL-GLOF-FRA | |
| Seifuku Densetsu: Pretty Fighter X 制服伝説 プリティ・ファイターX | SS | 1.002 | Original | | T-15001G | |
| Segata Sanshirou: Shinken Yuugi せがた 三四郎 ~真剣遊戯~ | SS | 1.001 | Original | | GS-9204 | |
| Segata Sanshirou: Choujin Densetsu せがた三四郎 超人伝説 | PC | | Original | | HCJ-0346 | |
| SegaSaturn Photo CD Operator セガサターン フォトCDオペレーター | SS | 1.010 | Original | | HSS-0121 | |
| SegaSaturn Internet Vol. 1 SEGASATURN インターネット Vol.1 | SS | 1.000 | Bundled with SegaSaturn Modem | | T-31301G | |
| Segare Ijiri せがれいじり | PSX | | Otameshi Disc | | SLPM 80426 | |
| Segare Ijiri せがれいじり | PSX | | Original | | SLPM 86230 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Sega Worldwide Soccer PC セガワールドワイドサッカーPC | PC | 1.09J | PCHome | | 506-9781 | |
| Sega Worldwide Soccer PC | PC | | Original | | MK 85056-50 | |
| Sega Worldwide Soccer 97 | SS | 1.000 | Original | | MK81112-50 | |
| Sega Worldwide Soccer 97 | SS | 1.000 | Original | | MK81112-50 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.004 | Original | | MK81123-50 | |
| Sega Worldwide Soccer '98: Club Edition | SS | 1.002 | Original | | MK81123-50 | |
| Sega Worldwide Soccer '98 セガ・ワールドワイド・サッカー’98 | SS | 1.002 | Original | | GS-9187 | |
| Sega Touring Car Championship | SS | 1.001 | Original, Sample | | 81216 | |
| Sega Touring Car Championship セガ・ツーリングカー・チャンピオンシップ | SS | 1.003 | Original | | GS-9164 | |
| Sega Touring Car Championship | PC | 1.0 | Original | | MK 85067-50 | |
| Sega Superstars Tennis | XBOX360 | | Original, Bundled with Xbox 360: Sega Superstars Tennis + Xbox Live Arcade Compilation Disc | | SE-2037 | |
| Sega Superstars Tennis | PS2 | 1.01 | Original | | SLUS 21733 | |
| Sega Superstars Tennis | PS2 | 1.01 | Original | | SLES-54946 … | |
| Sega Superstars | PS2 | 1.00 | Original, Bundled with EyeToy | | SLES-52834 | |
| Sega Sports Tennis | PS2 | 1.01 | Original | | SLUS 20480 | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSE-USA | |
| Sega Smash Pack: Volume 1 | DC | 1.002 | Original, Bundled with DC | | 51146 | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Smash Pack 2 | PC | | Original | | 673-01986 | |
| Sega Saturn de Hakken!! Tamagotchi Park セガサターンで発見!! たまごっちパーク | SS | 1.002 | Original | | T-13325G | |
| Sega Saturn Choice Cuts | SS | 2.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Saturn Choice Cuts | SS | 1.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Saturn Bootleg II: On the Road Sega Screams Volume 1 | SS | 1.002 | Not for Resale | | 81068, 81075 | |
| Sega Rally Revo Sega Rally | XBOX360 | | Original | | SE-2022 | |
| Sega Rally Championship Plus セガラリー・チャンピオンシップ・プラス | SS | 1.000 | Original, Satakore | | GS-9116, GS-9149 | |
| Sega Rally Championship PC | PC | 2.11 | Fair Game, Grabit | | FG-1282, GDL016 | |
| Sega Rally Championship PC | PC | 1.0 | Original | | MK 85048-50 | |
| Sega Rally Championship | SS | 1.006 | Original, Sega Saturn NetLink Bundle | | 80012, 81207 | |
| Sega Rally Championship 세가 랠리 | SS | 1.000 | Original | | GS-9506J | |
| Sega Rally Championship セガラリー・チャンピオンシップ | SS | 1.000 | Original | | GS-9047 | |
| Sega Rally Championship | SS | 1.000 | Original | | MK81207-50 | |
| Sega Rally Championship | SS | 1.000 | Original | | MK81207-50 | |
| Sega Rally 2006 セガラリー2006 | PS2 | 1.02 | Taikenban | | SLPM 61137 | |
| Sega Rally 2006 | PS2 | 1.00 | Original | | SLPM 66212 | |
| Sega Rally 2 セガ・ラリー2 | DC | 1.04 | Original | | HDR-0010 | |
| Sega Rally 2 (Install Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Play Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally | PC | 3.2.0.3 | Original, TopSeller | | | |
| Sega Rally (Uaktualnienie Wersji Polskiej) | PC | | Original, TopSeller | | | |
| Sega Rally | PSP | 2.00 | Original, PSP Essentials | | ULES-00910 … | |
| Sega Rally | PSP | 1.00 | Original | | ULES-00910 | |
| Sega Puzzle Pack | PC | | Original | | 673-01815 | |
| Sega PC Special Trydisc Vol. 1 Sega PC すべしゃる トライディスク Vol.1 | PC | | PC Game Bundle | | 670-9986 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11970 | |
| Sega PC Greatest Hits Series Vol. 2 | PC | | Taikenban, PC Game Bundle | | 670-10528 | |
| Sega PC Collection Vol. 2 | PC | | PC Game Bundle | | 673-04572 | |
| Sega Network Taisen Mahjong MJ4 Evolution セガネットワーク対戦麻雀MJ4 Evolution | LINDBERGH | 1.001 | Lindbergh Red EX | | DVP-0081 | |
| Sega Mega Drive Ultimate Collection | PS3 | 01.00 | Original | | BLES-00475 … | |
| Sega Mega Drive Ultimate Collection | XBOX360 | | Original, Classics | | SE-2085 | |
| Sega Mega Drive Collection | PS2 | 1.01 | Original | | SLES-54333 … | |
| Sega Mega Drive Classic Collection Volume 2 | PC | | Original | | SEGA-PC119 | |
| Sega Mega Drive Classic Collection Volume 1 | PC | | Original | | SEGA-PC118 | |
| Sega International Victory Goal セガ インターナショナル ビクトリー・ゴール | SS | 1.000 | Original | | GS-9044 | |
| Sega GT: Homologation Special セガGT ホモロゲーションスペシャル | DC | 1.006 | Original | | HDR-0054 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original, Xplosiv | | EI-1266-1, EI-1266-1 ENGLISH | |
| Sega GT | DC | 1.001 | Original, Sample | | 950-0103-50, MK-51053-50 | |
| Sega Genesis Collection | PS2 | 1.01 | Original | | SLUS 21542 | |
| Sega Flash Vol. 7 | SS | 1.000 | Bundled with Magazine | | MK610-6288G | |
| Sega Flash Vol. 6 | SS | 1.000 | Bundled with Magazine | | 610-6288F | |
| Sega Flash Vol. 5 | SS | 1.002 | Bundled with Magazine, Bundled with Sega Saturn | | 610-6288E | |
| Sega Flash Vol. 4 | SS | 1.003 | Bundled with Magazine | | 610-6288D | |
| Sega Flash Vol. 3 | SS | 1.004 | Bundled with Magazine | | 610-6288C | |
| Sega Flash Vol. 3 | SS | 1.001 | Bundled with Magazine | | 610-6288C | |
| Sega Flash Vol. 2 | SS | 1.000 | Bundled with Magazine, Bundled with Audio CD | | 610-6288B | |
| Sega Flash Vol. 1 | SS | 1.001 | Bundled with Sega Saturn | | MK610-6288A | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega Classics Collection | PS2 | 1.01 | Original | | SLUS 21009 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classic Arcade Collection: Limited Edition セガクラシック | MCD | | Original | | G-6012 | |
| Sega Bass Fishing Duel | PS2 | 1.01 | Original, Promo | | SLES-51388 | |
| Sega Bass Fishing | WII | | Original | | RVL-RBTP-EUR | |
| Sega Ages: Space Harrier セガエイジス スペース・ハリアー | SS | 1.002 | Original, Gentei Special Set | | GS-9108, GS-9111 | |
| Sega Ages: Power Drift セガエイジス パワー・ドリフト | SS | 1.001 | Original | | GS-9181 | |
| Sega Ages: Phantasy Star Collection セガ・エイジス ファンタシー・スター・コレクション | SS | 1.003 | Original | | GS-9186 | |
| Sega Ages: OutRun セガエイジス アウトラン | SS | 1.102 | Original | | GS-9110 | |
| Sega Ages: OutRun セガエイジス アウトラン | SS | 1.005 | Original | | GS-9110 | |
| Sega Ages: I Love Mickey Mouse: Fushigi no Oshiro Daibouken & I Love Donald Duck: Georgia Ou no Hihou セガエイジス アイ・ラブ・ミッキー・マウス ~ふしぎのお城 大冒険~ / アイ・ラブ・ドナルド・ダック ~グルジア王の秘宝~ | SS | 1.000 | Original | | GS-9179 | |
| Sega Ages: Galaxy Force II セガ・エイジス ギャラクシー・フォースⅡ | SS | 1.004 | Original | | GS-9197 | |
| Sega Ages: Fantasy Zone セガエイジス ファンタジー・ゾーン | SS | 1.001 | Original | | GS-9136 | |
| Sega Ages: Columns Arcade Collection セガエイジス コラムス・アーケード・コレクション | SS | 1.008 | Original | | GS-9161 | |
| Sega Ages: After Burner II セガエイジス アフターバーナーⅡ | SS | 1.001 | Original | | GS-9109 | |
| Sega Ages Volume 1 | SS | 1.003 | Original | | MK81604-50 | |
| Sega Ages 2500 Series Vol. 7: Columns セガエイジス2500シリーズ Vol.7 コラムス | PS2 | 1.01 | Original, Renkaban | | SLPM 62425 … | |
| Sega Ages 2500 Series Vol. 5: Golden Axe セガ・エイジス2500シリーズ Vol.5 ゴールデンアックス | PS2 | 1.02 | Original | | SLPM 62385 | |
| Sega Ages 2500 Series Vol. 4: Space Harrier セガ・エイジス2500シリーズVol.4 ~スペース・ハリアー~ | PS2 | 1.02 | Original, Renkaban | | SLPM 62384 … | |
| Sega Ages 2500 Series Vol. 32: Phantasy Star Complete Collection SEGA AGES 2500 シリーズ Vol.32 ファンタシースター コンプリートコレクション | PS2 | 1.00 | Original | | SLPM 62775 | |
| Sega Ages 2500 Series Vol. 3: Fantasy Zone セガ エイジス2500シリーズ Vol.3 ファンタジーゾーン | PS2 | 1.03 | Original | | SLPM 62366 | |
| Sega Ages 2500 Series Vol. 29: Monster World Complete Collection SEGA AGES 2500 シリーズ Vol.29 モンスターワールド コンプリートコレクション | PS2 | 1.01 | Original | | SLPM 62760 | |
| Sega Ages 2500 Series Vol. 28: Tetris Collection セガエイジス2500シリーズ Vol.28 テトリスコレクション | PS2 | 1.00 | Original | | SLPM 62746 | |
| Sega Ages 2500 Series Vol. 18: Dragon Force セガエイジス2500シリーズVol.18ドラゴンフォース | PS2 | 1.03 | Original | | SLPM 65778 | |
| Sega Ages 2500 Series Vol. 17: Phantasy Star Generation:2 セガエイジス2500シリーズ Vol.17 ファンタシースターgeneration:2 | PS2 | 1.00 | Original | | SLPM 62553 | |
| Sega Ages 2500 Series Vol. 15: DecAthlete Collection セガ・エイジス2500シリーズVol.15 デカスリート・コレクション | PS2 | 1.01 | Original, Renkaban | | SLPM 62444 … | |
| Sega Ages 2500 Series Vol. 13: OutRun セガ・エイジス2500シリーズVol.13 ~アウトラン~ | PS2 | 1.02 | Original, Renkaban | | SLPM 62447 … | |
| Sega Ages 2500 Series Vol. 12: Puyo Puyo Tsuu: Perfect Set セガ・エイジス2500シリーズVol.12 ぷよぷよ通 Perfect Set | PS2 | 1.01 | Original, Renkaban | | SLPM 62400 … | |
| Sega Ages 2500 Series Vol. 11: Hokuto no Ken セガ・エイジス2500シリーズVol.11 ~北斗の拳~ | PS2 | 1.02 | Original, Renkaban | | SLPM 62432 … | |
| Sega Ages 2500 Series Vol. 10: After Burner II セガエイジス2500シリーズVol. 10 アフターバーナーII | PS2 | 1.02 | Original | | SLPM 62446 | |
| Sega Ages 2500 Series Vol. 1: Phantasy Star Generation:1 セガエイジス2500シリーズ Vol.1 ファンタシースターgeneration:1 | PS2 | 1.02 | Genteiban | | SLPM 62362 | |
| Seek and Destroy | PS2 | 1.01 | Original | | SLUS 20606 | |
| Seek and Destroy | PS2 | 1.01 | Original | | SLES-51603 … | |
| Seek & Find Adventures | PC | | Original | | | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Secrets of Tatjana | CDI | | Original | | 810 0046 | |
| The Secrets of Da Vinci: The Forbidden Manuscript (Disc 2) | PC | 1.02 | Original | | | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLUS 20762 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | PS2 | 1.01 | Original | | SLES-51707 | |
| Secret Service: Wydanie Specjalne Alone in the Dark | PC | | | | | |
| Secret Service | PC | 1.0 | Original | | 35635.101.UK, 35635.101.US | |
| Secret Service | XBOX360 | | Original | | AV-2084 | |
| Secret Service | PS2 | 1.01 | Original | | SLUS 21836 | |
| The Secret Saturdays: Beasts of the 5th Sun | PS2 | 1.03 | Original | | SLES-55546 | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge The Monkey Island Bounty Pack: The Secret of Monkey Island & Monkey Island 2: LeChuck's Revenge | PC | 1.0 | LucasArts Classics: The Monkey Island Bounty Pack | | 3000012.101.UK | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PSX | | Original | | LSP-020780 … | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PSX | | Original | | LSP-020650 … | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PSX | | Original | | LSP-020570 … | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PSX | | Original | | LSP-020450 … | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PSX | | Original | | LSP-020280 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PSX | | Original | | LSP-020260 … | |
| The Secret of Googol 2b: Reshaping Googol: Under the Ocean | PSX | | Original | | LSP-020170 … | |
| The Secret of Googol 2a: Reshaping Googol: The Castle | PSX | | Original | | LSP-020180 … | |
| The Secret of Googol 1b: Reshaping Googol: The Tower | PSX | | Original | | LSP-020150 … | |
| The Secret of Googol 1a: Reshaping Googol: The Submarine | PSX | | Original | | LSP-020160 … | |
| Secret of Evangelion シークレット オブ エヴァンゲリオン | PS2 | 1.01 | Original, Best Hit Selection, Genteiban: Asuka Version, Genteiban: Ayanami Version | | SLPM 55084 … | |
| Secret Files: Tunguska (Disc 4) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 3) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 2) | PC | 1.0 | Original | | | |
| Secret Files: Tunguska (Disc 1) (Play Disc) | PC | 1.0 | Original | | | |
| Secret Agent Clank | PS2 | 1.00 | Original | | SCUS 97623 | |
| Secret Agent Clank | PSP | 1.00 | Demo | | UCUS 98707 | |
| Secre Volume 2: Mai Oikawa SECRE VOLUME ② 「及川 麻衣」 | FMT | | Original | | HME-180 | |
| Second Sight | XBOX | | Original | | CM-071 | |
| Second Sight | GC | | Original | | DL-DOL-GISP-EUR | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | XBOX | | Original | | AV-080 | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | PS2 | 1.00 | Original | | SLUS 21289 | |
| SeaWorld Adventure Parks Tycoon 2 SeaWorld Adventure Parks Tycoon 3D | PC | 1.0 | Original | | 35077.101.US | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| Seaman 2: Pekin Genjin Ikusei Kit シーマン2 ~北京原人育成キット~ | PS2 | 1.01 | Original, Sea-Mic Controller Doukonban | | SLPM 66685 | |
| Seaman 2: Pekin Genjin Ikusei Kit シーマン2 ~北京原人育成キット~ | PS2 | 1.00 | Taikenban | | SLPM 61163 | |
| SeaMail: Baby Gillman-hen: Ningen Kankei Shuufuku Hozen Pet シーメール 〈ベビーギルマン編〉 人間関係修復保全ペット | PC | 1.0 | Original | | VPC-0100 | |
| SeaBass Fishing 2 シーバス・フィッシング 2 | SS | 1.003 | Original, Satakore | | T-6011G, T-9114G | |
| SeaBass Fishing 2 シーバス・フィッシング 2 | PSX | | Original | | SLPS 00992 | |
| Sea Dogs: An Epic Adventure at Sea | PC | 1.06 | Original | | | |
| Sea Bass Fishing | SS | 1.002 | Original | | T-6009H-50 | |
| SD Gundam: Over Galaxian SDガンダム オーバーギャラクシアン | PSX | | Original | | SLPS 00385 | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Original | | SLPS 02915 | |
| SD Gundam: GGeneration-F (Disc 3) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02902 … | |
| SD Gundam: GGeneration-F (Disc 2) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02901 … | |
| SD Gundam: GGeneration-F (Disc 1) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02900 … | |
| SD Gundam: GGeneration-0 (Disc 2) SDガンダム ジージェネレーション・ゼロ | PSX | | Original | | SLPS 02201 | |
| SD Gundam: GGeneration-0 (Disc 1) SDガンダム ジージェネレーション・ゼロ | PSX | | Original | | SLPS 02200 | |
| SD Gundam: GGeneration World SDガンダム ジージェネレーション ワールド | PSP | 1.02 | Original, BigHits | | ULJS 00363 … | |
| SD Gundam: GGeneration Spirits: G-Spirits SDガンダム ジージェネレーション スピリッツ | PS2 | 1.02 | Original | | SLKA 25413 … | |
| SD Gundam: GGeneration Seed SDガンダムジージェネレーションSEED | PS2 | 1.02 | Original, Gundam the Best | | SLPS 25492 … | |
| SD Gundam: GGeneration Portable SDガンダム ジージェネレーション・ポータブル | PSP | 1.02 | Original, PSP the Best | | ULJS 00065 … | |
| SD Gundam: GGeneration Neo SDガンダム ジージェネレーション・ネオ | PS2 | 1.03 | Original, Gundam the Best | | SLPS 25170 … | |
| SD Gundam: GGeneration (Premium Disc) SDガンダム ジージェネレーション プレミアムディスク | PSX | | Original | | SLPS 01561 | |
| SD Gundam: GGeneration SDガンダム ジージェネレーション | PSX | Rev 1 | Original, PlayStation the Best | | SLPS 01560 … | |
| SD Gundam: GGeneration SDガンダム ジージェネレーション | PSX | | Original | | SLPS 01560 | |
| SD Gundam: GCentury S SDガンダム・ジー・センチュリーS | SS | 1.001 | Original | | T-13324G | |
| SD Gundam: GCentury SDガンダム ジーセンチュリー | PSX | | Original | | SCPS 45034 … | |
| SD Gundam: GCentury SDガンダム ジーセンチュリー | PSX | Rev 1 | PlayStation the Best | | SLPS 91065 | |
| SD Gundam: Daizukan SDガンダム ~大図鑑~ | QIS | | Original | | BAPD-03 | |
| SD Gundam Force: Showdown! | PS2 | 1.01 | Original | | SLUS 20698 | |
| SD Gundam Eiyuuden: Daikessen!! Kishi vs. Musha SDガンダム英雄伝 大決戦!! 騎士 VS 武者 | PSX | | Original | | SLPS 03145 | |
| Scud: The Disposable Assassin | SS | 1.015 | Original | | 14003 | |
| Screen Club: Pocket Monsters スクリーンクラブ ポケットモンスター | PC | | Original | | | |
| ScreamRide | XBOX360 | | Original | | MS-2726 | |
| Screamer Rally | PC | sov 2.1 | Sold Out Software | | sov. 2.1 | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | Screamer Injection | | | |
| Scrabble Interactive: 2005 Edition | PC | 1.0 | Covermount: Special Edition | | | |
| Scrabble Interactive | PS2 | 1.03 | Original | | SLES-51150 … | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PSX | | Original | | SLUS-00903 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| The Scorpion King: Rise of the Akkadian | PS2 | 1.01 | Original | | SLES-50987 | |
| Score International Baja 1000: World Championship Off Road Racing Score International Baja 1000: The Official Game | XBOX360 | | Original | | AV-2083 | |
| Scorcher | SS | 2.000 | Original | | 81214 | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Scorcher | PC | | Original | | | |
| Scooby-Doo! Unmasked | XBOX | | Original | | TQ-247 | |
| Scooby-Doo! Showdown in Ghost Town | PC | 1.0.1.8 | SoftKey | | SGW854BB, SGW854BB-CD | |
| Scooby-Doo! Priklyucheniya v gorode prizrakov Скуби-Ду! Приключения в городе призраков | PC | | 1C: Igroteka | | | |
| Scooby-Doo! Night of 100 Frights | PS2 | 1.01 | Original, Greatest Hits | | SLUS 20349 … | |
| Scooby-Doo! Night of 100 Frights | PS2 | 1.01 | Original | | SLES-51017 | |
| Scooby-Doo! Mystery Mayhem | XBOX | | Original | | TQ-014 | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3E-USA | |
| Scooby-Doo! Mystery Mayhem | PS2 | 1.01 | Original, Platinum: The Best of PlayStation 2 | | SLES-51883 … | |
| Scooby-Doo! First Frights | WII | | Original | | RVL-RQNP-EUR-B0, RVL-RQNP-EUR-B1 | |
| Scooby-Doo! Case File #1: The Glowing Bug Man | PC | 1.0 | Original, Scholastic | | 381681-CD, 381681-CD SP1 | |
| Scooby-Doo! and the Spooky Swamp | PS2 | 1.01 | Original | | SLUS 21928 | |
| Scooby-Doo! and the Spooky Swamp | WII | | Original | | RVL-SJ2P-EUR-B0 | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! | IXL | 2.0.0 | Original | | R9709 | |
| Sci-Fi Saturday Arcade | PC | 1.0 | Covermount | | TS055 | |
| Sci-Fi Pinball | PC | | Original | | | |
| Das Schwarze Auge: Schatten über Riva | PC | 1.00 | Original | | SPI 032 | |
| Das Schwarze Auge: Drakensang: Phileassons Geheimnis | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Das Schwarze Auge: Drakensang | PC | 1.11 | Software Pyramide | | | |
| Das Schwarze Auge: Drakensang | PC | | Original, Limited Collector's Edition | | | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| School Rumble: Neru Musume wa Sodatsu. スクール・ランブル ~ねる娘は育つ。~ | PS2 | 1.01 | Original, Best Collection | | SLPS 25540 … | |
| School Love! Koi to Kibou no Metronome すくぅ~る・らぶっ! ~恋と希望のメトロノーム~ | PS2 | 1.01 | Shokai Genteiban | | SLPM 66612 | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Scholastic's The Magic School Bus Explores the Solar System | PC | 1.00.0000 | Original | | 0396 Part No. 90618, 1001 Part No. X08-51174, Disc Assy. 296-052-002 | |
| Scholastic's The Magic School Bus Explores the Ocean | PC | 1.0 | Original, The Magic School Bus: Bonus Pack | | 0396 Part No. 90626, Disc Assy. 451-052-012 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| Scholastic's The Magic School Bus Explores Bugs | PC | 1.0.0.1 | Original, The Magic School Bus: Bonus Pack | | 0100 Part No. X05-52861, 1001 Part No. X08-51053 | |
| Schoenbrunn | PHOTO-CD | | Original | | | |
| Schmidt Interaktivspaß: Solitaire | PC | 1.0.0.0 | Original | | S0023093 | |
| Schmidt Interaktivspass: Doppelkopf | PC | 1.0.0.0 | Original | | S0022421 | |
| Schleichfahrt | PC | | Original, Classics | | | |
| Schlag den Raab: Das 3. Spiel | WII | | Original | | RVL-SUYD-GER-B0 | |
| Schizm: Mysterious Journey (Disc 5) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 4) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 3) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 2) | PC | 1.0.0.744 | Original | | | |
| Schizm: Mysterious Journey (Disc 1) | PC | 1.0.0.744 | Original | | | |
| Scene It? Twilight | WII | | Original | | RVL-SCNP-EUR-B0 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCP-UKV-B0 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| SCEE Hits Demo | PS2 | 1.02 | | | SCED-52970 | |
| SCEE Catalogue Video 3+ | PS2 | 1.00 | Demo | | SCED-51278 | |
| SCEE Catalogue Video | PS2 | 1.01 | | | SCED-51187 | |
| Scavenger 4 スカベンジャー4 | FMT | Rev B | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217B | |
| Scavenger 4 スカベンジャー4 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217 | |
| Scarface: The World Is Yours | XBOX | | Original | | VU-063 | |
| Scarface: The World Is Yours | PS2 | 1.00 | Original, Collector's Edition | | SLUS 21111 … | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCD-NOE | |
| Scarface: The World Is Yours | PS2 | 1.01 | Original, Platinum: The Best of PlayStation 2 | | SLES-54182 | |
| Scarface: The World Is Yours | PS2 | 1.00 | Original | | SLES-54271 | |
| Scarface: Money. Power. Respect. | PSP | 1.02 | Original | | ULES-00546 | |
| Scared Rider Xechs スカーレッドライダーゼクス | PS2 | 1.01 | Original, Genteiban | | SLPM 55265 … | |
| SCAR: Squadra Corse Alfa Romeo | PS2 | 1.01 | Original, Promo | | SLES-53320 | |
| Scandal スキャンダル | PS2 | 1.00 | Original | | SCPS 15001 | |
| Scaler | XBOX | | Original | | TT-122 | |
| Scaler | PS2 | 1.01 | Original | | SLES-52917 | |
| SBK: Superbike World Championship | PS2 | 1.01 | Original | | SLUS 21817 | |
| SBK-07: Superbike World Championship | PS2 | 1.01 | Original, Promo | | SLES-54705 … | |
| SBK 2011: FIM Superbike World Championship | PS3 | 01.00 | Original | | BLES-01226 | |
| SBK 08: Superbike World Championship | PC | | Covermount | | | |
| Saw II: Flesh & Blood | XBOX360 | | Original | | KN-2082 | |
| Saw II: Flesh & Blood | PS3 | 01.00 | Original | | BLES-01050 | |
| Savage: The Battle for Newerth (Game Disc) | PC | 2.00c | Original | | | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Savage: The Battle for Newerth | PC | | Bundle Version ASUS OEM | | V471 | |
| Savage Skies | PS2 | 1.02 | Original | | SLUS 20430 | |
| Savage Skies | PS2 | 1.03 | Original | | SLES-51292 | |
| Saturn Super Vol. 9 Furoku CD-ROM サターン・スーパー Vol.9 付録CD‐ROM | SS | 1.000 | | | 610-6020-10 | |
| Saturn Super Vol. 5 サターン・スーパー Vol.5 | SS | 1.000 | | | 610-6020-006 | |
| Saturn Super Vol. 10 Furoku CD-ROM サターン・スーパー Vol.10 付録CD‐ROM | SS | 1.000 | | | 610-6020-11 | |
| Saturn Super Vol. 1 サターン・スーパー Vol.1 | SS | 1.000 | | | 610-6020-01 | |
| Saturn Super Henshuubu Hen: Taikenban Saturn Soft Taizen サターン・スーパー 編集部 編 体験版サターンソフト大全 | SS | 1.000 | | | 610-6020-04 | |
| Saturn Music School 2 サターンミュージックスクール2 | SS | 1.003 | Original | | T-32803G | |
| Saturn Music School サターンミュージックスクール | SS | 1.004 | Original, Bundled with Keyboard | | T-32801G | |
| Saturn CG Selection Vol. 1 サターンCGセレクション Vol.1 | SS | 1.001 | Bundled with Book | | 610-6113 | |
| Saturn Bomberman | SS | 1.003 | Original | | 81070 | |
| Saturn Bomberman サターン・ボンバーマン | SS | 1.001 | SegaNet Sen'you | | T-14305G | |
| Saturn Bomberman | SS | 1.000 | Original | | MK81070-50 | |
| Satomi no Nazo 里見の謎 | PSX | | Original | | SLPS 00613 | |
| Satazius Next サタゼウスネクスト | DC | 1.000 | Unlicensed | | | |
| Saru! Get You! SaruSaru Daisakusen サルゲッチュ サルサル大作戦 | PSP | 1.00 | Original, PSP the Best | | UCJS 10060 … | |
| Saru! Get You! Piposaru Racer サルゲッチュ ピポサルレーサー | PSP | 1.00 | Original, PSP the Best | | UCAS 40134 … | |
| Saru! Get You! P! サルゲッチュP! | PSP | 2.00 | PSP the Best, PSP Natsutoku-matsuri | | UCAS 40090 … | |
| Saru! Get You! Million Monkeys サルゲッチュ ミリオンモンキーズ | PS2 | 1.02 | Original | | SCPS 15115 | |
| Saru! Get You! Million Monkeys サルゲッチュ ミリオンモンキーズ | PS2 | 1.00 | Taikenban | | PCPX 98041 | |
| Saru! Get You! 3 サルゲッチュ3 | PS2 | 1.04 | Original, PlayStation 2 the Best, PlayStation 2 the Best Reprint | | SCAJ 20138 … | |
| Saru! Get You! 2 サルゲッチュ2 | PS2 | 1.02 | Original, PlayStation 2 the Best, PlayStation 2 the Best Reprint | | SCPS 15025 … | |
| Saru! Get You! サルゲッチュ | PSX | | Taikenban | | PAPX 90079 … | |
| Saru! Get You! サルゲッチュ | PSX | Rev 1 | PlayStation the Best for Family | | SCPS 91196 | |
| Saru! Get You! サルゲッチュ | PSX | | Original | | SCPS 10091 | |
| Saru Get You P! サルゲッチュP! | PSP | 1.06 | Original | | UCJS 10004 | |
| Sargon Chess | CDI | | Original, Original: Longbox | | 310690030-2 | |
| Sargon Chess | CDI | | Original | | 310690030-2, 690 030-2, 690 0302, 699 030-2, 812 0024, 814 0042 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshi-tachi (Disc 3) さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02763 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshi-tachi (Disc 2) さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02762 | |