Region | Title | System | Version | Edition | Languages | Serial | Status |
| S.C.A.R.S. | PSX | | Demo | | SLED-01415 | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl (Bonus DVD) | PC | | Radiation Edition | | 4005209088800 / 4005209089029, 4005209089036 / 4005209089006, 4005209089180, 4005209089340 / 4005209089012 | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | | Original, Radiation Edition | | | |
| S.T.A.L.K.E.R.: Shadow of Chernobyl | PC | | Original | | 4005209055413 / 4005209089180 | |
| S.T.O.R.M. (Disc 1) | PC | | Original | | A541W3GD[1] | |
| S.T.O.R.M. (Disc 2) | PC | | Original, Dice | | A541W3GD[2], DMM 031730 | |
| S.T.O.R.M. (Disc 3) | PC | | Original, Dice | | A541W3GD[3], DMM 031730 | |
| S³: Silent Storm: Sentinels | PC | | Gold Edition | | ROSILENTST0004lab, ROSILENTST0006lab3 | |
| Saban's Isnogud | PC | | Original | | CD 1356420/A | |
| Saban's Power Rangers: Lightspeed Rescue | PSX | | Original | | SLES-03286 … | |
| Saban's Power Rangers: Time Force | PC | | PC Fun Club, THQ Double Pack (Focus Essential) | | ESS589, PFC024/D | |
| Saber Marionette J: Battle Sabers セイバーマリオネットJ バトルセイバーズ | PSX | | Shokai Genteiban | | SLPS 00738 | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| The Saboteur | XBOX360 | | Original | | EA-2191 | |
| Sabrina the Teenage Witch: A Twitch in Time! | PSX | | Original | | SLUS-01208 | |
| Sacred 2: Fallen Angel (Disc 2) Sacred 2: Падший ангел | PC | | Original | | | |
| Sacred 2: Fallen Angel | XBOX360 | | Original | | KM-2001 | |
| Sacred 3 | XBOX360 | | Original | | KM-2023 | |
| Sacrifice | PC | | Bundle Version ASUS OEM | | CD-C951041-AS2E | |
| Safecracker | PC | | Action-Games | | 80271 | |
| Safecracker | PC | | Original, Gamez Classic / PC Zone Benelux Klassieker | | | |
| Saga Baldur's Gate | PC | | eXtra Klasyka GOLD | | | |
| SaGa Frontier サガフロンティア | PSX | | Original, PSone Books, Ultimate Hits | | SCPS 45102 … | |
| SaGa Frontier II サガフロンティアII | PSX | | Original, Square Millennium Collection, PSone Books | | SCPS 45400 … | |
| Saga The Settlers I-IV (The Settlers I + II) | PC | | eXtra Klasyka XK Gold | | | |
| Sage: Rage of Kings | PC | | Covermount | | | |
| Saikyou Toudai Shougi 最強 東大将棋 | PSX | | Original, Mycom Best | | SLPS 01679 … | |
| Saikyou Toudai Shougi 2 最強 東大将棋2 | PSX | | Original, Mycom Best | | SLPS 02397 … | |
| Sailing | CDI | | Original, Demonstration Disc | | 310-690-101-2, 310690101-2 | |
| Saint Diary: Kiyoka-chan no Nikki せいんと・だいありぃ ~聖ちゃんの日記~ | PC-98 | | Original | | EXC-004 | |
| Saint Seiya: Typing Ryuuseiken 聖闘士星矢 タイピング流星拳 | PC | | Original | | | |
| Saints Row | XBOX360 | | Original, Classics | | TQ-2029 | |
| Saints Row | XBOX360 | | Demo | | IM-2022 | |
| Saints Row 세인츠 로우 | XBOX360 | | Original, Classics, Platinum Hits, Saints Row Double Pack | | TQ-2001 | |
| Saints Row 2 | XBOX360 | | Original, Classics, Platinum Hits, Promo, Saints Row Double Pack | | TQ-2044 | |
| Saints Row IV | XBOX360 | | Original, Commander in Chief Edition | | KM-2038 | |
| Saints Row IV | PC | | Original, Commander in Chief Edition | | 1720120 | |
| Saints Row IV: National Treasure Edition (Disc 1) (Installation Disc) Saints Row IV: Game of the Century Edition | XBOX360 | | Original | | KM-2038 | |
| Saints Row IV: National Treasure Edition (Disc 2) Saints Row IV: Game of the Century Edition | XBOX360 | | Original | | KM-2038 | |
| Saints Row: Gat out of Hell | XBOX360 | | Original | | KM-2048 | |
| Saints Row: The Third (Disc 1) | PC | | Original | | P_40065_06A_PL | |
| Saints Row: The Third (Disc 2) | PC | | Original | | P_40065_06A_PL | |
| Saints Row: The Third | XBOX360 | | Original, The Full Package (Disc 2) | | TQ-2213 | |
| Saints Row: The Third | XBOX360 | | Original, The Full Package | | TQ-2157 | |
| Saints Row: The Third | XBOX360 | | Original, The Full Package (Disc 2) | | TQ-2157 | |
| Saints Row: The Third: The Full Package (Disc 2) (Install Disc) | XBOX360 | | Original | | TQ-2157 | |
| Saints Row: The Third: The Full Package (Disc 1) (DLC Installer) | XBOX360 | | Original | | TQ-2157 | |
| Saishuu Densha 最終電車 | PSX | | Original, Renkaban | | SLPS 01257 … | |
| Saishuu Densha 最終電車 | PSX | | Taikenban | | SLPM 80215 | |
| Sakuma-shiki Jinsei Game さくま式人生ゲーム | PSX | | Original | | SLPS 01740 | |
| Sakura Taisen (Disc 1) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00190, 673-01919 | |
| Sakura Taisen (Disc 2) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00191, 673-01920 | |
| Sakura Taisen (Disc 3) サクラ大戦 | PC | | Shokai Genteiban, Fukyuuban | | 673-00192, 673-01921 | |
| Sakura Taisen: Teigeki Secret File サクラ大戦 ~帝劇シークレット・ファイル~ | PHOTO-CD | | Magazine Bundle | | SSMP-00001 | |
| Sakura Wars (Disc 1) (Igrovoj) Войны Сакуры | PC | | Original | | | |
| Sakura Wars (Disc 2) Войны Сакуры | PC | | Original | | | |
| Salamander Deluxe Pack Plus 沙羅曼蛇 DELUXE PACK PLUS | PSX | | Original | | SLPM 86037 | |
| Salaryman Champ: Tatakau Salaryman サラリーマン・チャンプ ~たたかうサラリーマン~ | PSX | | Original | | SLPM 86820 | |
| Salaryman Kintarou: Dai-3-kan Touhoku Dotou-hen サラリーマン金太郎:第3巻東北怒涛篇 | PC | | Original | | | |
| Salzburg no Majo ザルツブルグの魔女 | PC | | Original | | | |
| Sam & Max Hit the Road | PC | | Softgold, Rerelease | | | |
| Sam & Max Hit the Road | PC | | Collezione CD-Rom by C.T.O. | | | |
| Samba de Amigo | WII | | Original | | RVL-R3BP-EUR | |
| Samurai Shodown サムライ・ショーダウン | 3DO | | Original | | FZ-SJ3155 | |
| Samurai Shodown | 3DO | | Original | | | |
| Samurai Spirits ~ Samurai Shodown サムライ・スピリッツ | NGCD | | Original | | NGCD-045 | |
| Samurai Spirits Sen サムライスピリッツ閃 | XBOX360 | | Original | | SN-2005 | |
| Samurai Spirits: Amakusa Kourin ~ Samurai Shodown IV: Amakusa's Revenge サムライ・スピリッツ ~天草降臨~ | NGCD | | Original | | NGCD-222, NGCD-222E | |
| Samurai Spirits: Amakusa Kourin Special サムライスピリッツ 天草降臨スペシャル | PSX | | Original, PSone Books (SNK Best Collection) | | SLPS 01171 … | |
| Samurai Spirits: Kenkaku Shinan Pack サムライスピリッツ 剣客指南パック | PSX | | Original, Sample | | SCPS 45209 … | |
| Samurai Spirits: Zankurou Musouken サムライスピリッツ 斬紅郎無双剣 | PSX | | Original, PSone Books (SNK Best Collection) | | SLPS 00350 … | |
| Samurai Spirits: Zankurou Musouken ~ Samurai Shodown III サムライ・スピリッツ 斬紅郎無双剣 | NGCD | | Original | | NGCD-087, NGCD-087E | |
| Samurai Warriors 2 | PC | | Original | | 04929UK | |
| Samurai Warriors 2 | XBOX360 | | Original | | KO-2005 | |
| The San Diego Zoo Presents... The Animals! | 3DO | | Original | | | |
| San Francisco Rush: Extreme Racing | PSX | | Original | | SLES-01208 | |
| Sandy's Circus Adventure | CDI | | Original, Demonstration Disc | | 310-690-022-2, 310690022-2, 699 022-2 | |
| Sangoku Musou 三國無双 | PSX | | Tentou Taikenban CD-ROM | | SLPM 80085 | |
| Sangoku Musou 三國無双 | PSX | | Original | | SLPS 00731 | |
| Sangokushi Gekiten 三國志撃天 | PC | | Original | | | |
| Sangokushi III 三國志Ⅲ | FMT | | with Soundware | | HMD-131 | |
| Sangokushi III 三國志Ⅲ | PCE | | Original | | KOCD3003 | |
| Sangokushi IV 三國志Ⅳ | FMT | | with Soundware | | HMF-139 | |
| Sangokushi Koumeiden 三國志孔明伝 | PSX | | Original, Koei the Best | | SLPM 86205 … | |
| Sangokushi V 三國志Ⅴ | PC-98 | | Original | | KN11-00103 | |
| Sangokushi V 三國志Ⅴ | PC-98 | | Original | | KN11-00103 | |
| Sangokushi V 三國志Ⅴ | PSX | | Original | | SLPS 00703 | |
| Sangokushi VI 三國志Ⅵ | PSX | | Original, PlayStation the Best | | SCPS 45327 … | |
| Sangokushi VI with Power-Up Kit 三國志Ⅵ with パワーアップキット | PSX | | Original | | SLPM 86312 | |
| Sangokushi VII 三國志Ⅶ | PSX | | Original | | SLPM 86728 | |
| Sangokushi: Eiketsu Tenka ni Nozomu 三国志 ~英傑天下に臨む~ | PCE | | Original | | NXCD0002 | |
| Sanitarium (Disc 2) | PC | | Original | | | |
| Sanitarium (Disc 3) | PC | | Original | | | |
| Sanitary Podzemelij Санитары Подземелий | PC | | Original, 1C: Kollekciya igrushek | | | |
| Sankyo Fever: Jikki Simulation SANKYO FEVER 実機シミュレーション | PSX | | Original | | SLPS 00264 | |
| Sankyo Fever: Jikki Simulation Vol. 2 SANKYO FEVER 実機シミュレーション Vol.2 | PSX | | Original | | SLPS 01176 | |
| Sanmi Ittai 三位一体 | PSX | | Taikenban | | SLPM 80065 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Dice | | DMM 011143 | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 1) | PC | | Original | | | |
| Santa Fe Mysteries: The Elk Moon Murder (Disc 2) | PC | | Original | | | |
| Sanyo Pachinko Paradise 三洋パチンコパラダイス | PSX | | Original | | SLPS 02164 | |
| Sanyo Pachinko Paradise 3: Wan Wan Daikoushin 三洋パチンコパラダイス3 ~わんわん大行進~ | PSX | | Original | | SLPS 02633 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshi-tachi (Disc 1) さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02761 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshi-tachi (Disc 2) さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02762 | |
| Saraba Uchuu Senkan Yamato: Ai no Senshi-tachi (Disc 3) さらば宇宙戦艦ヤマト 愛の戦士たち | PSX | | Original, Sample | | SLPS 02763 | |
| Sargon Chess | CDI | | Original | | 310690030-2, 690 030-2, 690 0302, 699 030-2, 812 0024, 814 0042 | |
| Sargon Chess | CDI | | Original, Original: Longbox | | 310690030-2 | |
| Saru! Get You! サルゲッチュ | PSX | | Original | | SCPS 10091 | |
| Saru! Get You! サルゲッチュ | PSX | | Taikenban | | PAPX 90079 … | |
| Satomi no Nazo 里見の謎 | PSX | | Original | | SLPS 00613 | |
| Savage: The Battle for Newerth | PC | | Bundle Version ASUS OEM | | V471 | |
| Savage: The Battle for Newerth (Bonus Disc) | PC | | Original | | | |
| Saw II: Flesh & Blood | XBOX360 | | Original | | KN-2082 | |
| SBK 08: Superbike World Championship | PC | | Covermount | | | |
| Scaler | XBOX | | Original | | TT-122 | |
| Scarface: The World Is Yours | WII | | Original | | RVL-RSCD-NOE | |
| Scarface: The World Is Yours | XBOX | | Original | | VU-063 | |
| Scavenger 4 スカベンジャー4 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 39 | | HME-217 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| Scene It? Box Office Smash! | XBOX360 | | Original | | MS-2144 | |
| Scene It? Bright Lights! Big Screen! | WII | | Original | | RVL-SSCP-UKV-B0 | |
| Scene It? Twilight | WII | | Original | | RVL-SCNP-EUR-B0 | |
| Schlag den Raab: Das 3. Spiel | WII | | Original | | RVL-SUYD-GER-B0 | |
| Schleichfahrt | PC | | Original, Classics | | | |
| Schoenbrunn | PHOTO-CD | | Original | | | |
| Scholastic's The Magic School Bus: Whales & Dolphins: Activity Center | PC | | The Magic School Bus: Bonus Pack Volume 3, The Magic School Bus: Bonus Pack | | 0201 Part No. X06-15571 | |
| Schoolhouse Rock! 1st & 2nd Grade (Disc 2) (2nd Grade) | PC | | Original | | 21330CD-2, SGE744AE-CD2 | |
| Schoolhouse Rock! Math Rock | PC | | Original | | 21010CD | |
| Das Schwarze Auge: Drakensang | PC | | Original, Limited Collector's Edition | | | |
| Das Schwarze Auge: Drakensang: Am Fluss der Zeit | PC | | Original | | | |
| Das Schwarze Auge: Drakensang: Phileassons Geheimnis | PC | | Original | | | |
| Sci-Fi Pinball | PC | | Original | | | |
| Scooby-Doo! Ancient Adventure | VFLASH | | Original | | 093080(US) | |
| Scooby-Doo! and the Spooky Swamp | WII | | Original | | RVL-SJ2P-EUR-B0 | |
| Scooby-Doo! First Frights | WII | | Original | | RVL-RQNP-EUR-B0, RVL-RQNP-EUR-B1 | |
| Scooby-Doo! Mystery Mayhem | GC | | Original | | DL-DOL-GC3E-USA | |
| Scooby-Doo! Mystery Mayhem | XBOX | | Original | | TQ-014 | |
| Scooby-Doo! Priklyucheniya v gorode prizrakov Скуби-Ду! Приключения в городе призраков | PC | | 1C: Igroteka | | | |
| Scooby-Doo! Unmasked | XBOX | | Original | | TQ-247 | |
| Scorcher | PC | | Original | | | |
| Scorcher | PC | | Original | | 04-11264CD | |
| Score International Baja 1000: World Championship Off Road Racing Score International Baja 1000: The Official Game | XBOX360 | | Original | | AV-2083 | |
| Scrabble | PC | | General Mills | | AM0703R72 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Scholastic, Classic Value Series | | 99002 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002 | |
| Scrabble | PSX | | Original | | SLUS-00903 | |
| Scrabble Scrabble: CD-ROM Crossword Game | PC | | Rerelease | | 99002, 99002● | |
| Scrabble Complete | PC | | Original, Bundle Version Microgistix OEM | | 11290-CD, Part # 23970CD | |
| Screamer | PC | | Original | | | |
| Screamer | PC | | Screamer Injection | | | |
| Screamer 2 | PC | | Megapak 8 | | | |
| Screamer 2 Screamer 2: Sheer Speed Road Racing | PC | | Original | | D83011 | |
| Screamer Rally | PC | | Original, Screamer Injection | | | |
| ScreamRide | XBOX360 | | Original | | MS-2726 | |
| Screen Club: Pocket Monsters スクリーンクラブ ポケットモンスター | PC | | Original | | | |
| SD Gundam Eiyuuden: Daikessen!! Kishi vs. Musha SDガンダム英雄伝 大決戦!! 騎士 VS 武者 | PSX | | Original | | SLPS 03145 | |
| SD Gundam: Daizukan SDガンダム ~大図鑑~ | QIS | | Original | | BAPD-03 | |
| SD Gundam: GCentury SDガンダム ジーセンチュリー | PSX | | Original | | SCPS 45034 … | |
| SD Gundam: GGeneration SDガンダム ジージェネレーション | PSX | | Original | | SLPS 01560 | |
| SD Gundam: GGeneration (Premium Disc) SDガンダム ジージェネレーション プレミアムディスク | PSX | | Original | | SLPS 01561 | |
| SD Gundam: GGeneration-0 (Disc 1) SDガンダム ジージェネレーション・ゼロ | PSX | | Original | | SLPS 02200 | |
| SD Gundam: GGeneration-0 (Disc 2) SDガンダム ジージェネレーション・ゼロ | PSX | | Original | | SLPS 02201 | |
| SD Gundam: GGeneration-F (Disc 1) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02900 … | |
| SD Gundam: GGeneration-F (Disc 2) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02901 … | |
| SD Gundam: GGeneration-F (Disc 3) SDガンダム ジージェネレーション・エフ | PSX | | Original, Limited Edition | | SLPS 02902 … | |
| SD Gundam: GGeneration-F (Disc 4) (Premium Disc) SDガンダム ジージェネレーション・エフ | PSX | | Original | | SLPS 02915 | |
| SD Gundam: Over Galaxian SDガンダム オーバーギャラクシアン | PSX | | Original | | SLPS 00385 | |
| SeaBass Fishing 2 シーバス・フィッシング 2 | PSX | | Original | | SLPS 00992 | |
| SeaWorld Adventure Parks Tycoon | PC | | Original | | 31711.101.US | |
| SeaWorld Adventure Parks: Shamu's Deep Sea Adventures | XBOX | | Original | | AV-080 | |
| Second Sight | GC | | Original | | DL-DOL-GISP-EUR | |
| Second Sight | XBOX | | Original | | CM-071 | |
| Secre Volume 2: Mai Oikawa SECRE VOLUME ② 「及川 麻衣」 | FMT | | Original | | HME-180 | |
| The Secret of Googol 1a: Reshaping Googol: The Submarine | PSX | | Original | | LSP-020160 … | |
| The Secret of Googol 1b: Reshaping Googol: The Tower | PSX | | Original | | LSP-020150 … | |
| The Secret of Googol 2a: Reshaping Googol: The Castle | PSX | | Original | | LSP-020180 … | |
| The Secret of Googol 2b: Reshaping Googol: Under the Ocean | PSX | | Original | | LSP-020170 … | |
| The Secret of Googol 3: The Googol Counting Fair: Midways | PSX | | Original | | LSP-020260 … | |
| The Secret of Googol 4: The Googol Counting Fair: Corral / Fun House | PSX | | Original | | LSP-020280 … | |
| The Secret of Googol 5: Googolfest: Party Isle / Toy Isle | PSX | | Original | | LSP-020450 … | |
| The Secret of Googol 6: Googolfest: Arcade Isle / Moon Feast Isle | PSX | | Original | | LSP-020570 … | |
| The Secret of Googol 7: Eggs All Around: Egg Trek / Balloon Picnic | PSX | | Original | | LSP-020650 … | |
| The Secret of Googol 8: Googol Gulch: General Store / Math Arcade | PSX | | Original | | LSP-020780 … | |
| The Secret of the Silver Earring Sherlock Holmes: The Secret of the Silver Earring | PC | | Rerelease (DVD-ROM) | | DVD590CD | |
| Secret Service | XBOX360 | | Original | | AV-2084 | |
| Secret Service: Wydanie Specjalne Alone in the Dark | PC | | | | | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| Secret Weapons over Normandy | XBOX | | Original | | LA-006 | |
| The Secrets of Atlantis: The Sacred Legacy | PC | | Original | | | |
| Secrets of Tatjana | CDI | | Original | | 810 0046 | |
| Section 8 | XBOX360 | | Original | | GP-2004 | |
| Seek & Find Adventures | PC | | Original | | | |
| Sega Bass Fishing | WII | | Original | | RVL-RBTP-EUR | |
| Sega Classic Arcade Collection: Limited Edition セガクラシック | MCD | | Original | | G-6012 | |
| Sega Classics Arcade Collection: Limited Edition | MCD | | Original | | 4127 | |
| Sega Dreamcast Wired by AT&T WorldNet Service | PC | | Promo | | | |
| Sega GT (Disc 1) (Installation Disc) | PC | | Original, Xplosiv | | EI-1266-1, EI-1266-1 ENGLISH | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega GT 2002 + JSRF: Jet Set Radio Future | XBOX | | Bundled with Xbox | | MS-061 | |
| Sega Mega Drive Classic Collection Volume 1 | PC | | Original | | SEGA-PC118 | |
| Sega Mega Drive Classic Collection Volume 2 | PC | | Original | | SEGA-PC119 | |
| Sega Mega Drive Ultimate Collection | XBOX360 | | Original, Classics | | SE-2085 | |
| Sega PC Collection Vol. 2 | PC | | PC Game Bundle | | 673-04572 | |
| Sega PC Greatest Hits Series Vol. 2 | PC | | Taikenban, PC Game Bundle | | 670-10528 | |
| Sega PC Greatest Hits Series Vol. 3 | PC | | Demo | | 670-11970 | |
| Sega PC Special Trydisc Vol. 1 Sega PC すべしゃる トライディスク Vol.1 | PC | | PC Game Bundle | | 670-9986 | |
| Sega Puzzle Pack | PC | | Original | | 673-01815 | |
| Sega Rally (Uaktualnienie Wersji Polskiej) | PC | | Original, TopSeller | | | |
| Sega Rally Revo Sega Rally | XBOX360 | | Original | | SE-2022 | |
| Sega Smash Pack 2 | PC | | Original | | 673-01986 | |
| Sega Smash Pack Twin Pack | PC | | Original | | 30884.101.US | |
| Sega Soccer Slam | GC | | Original | | DL-DOL-GSSE-USA | |
| Sega Superstars Tennis | XBOX360 | | Original, Bundled with Xbox 360: Sega Superstars Tennis + Xbox Live Arcade Compilation Disc | | SE-2037 | |
| Sega Worldwide Soccer PC | PC | | Original | | MK 85056-50 | |
| Sega's Trident Sampler Disc | PC | | PC Hardware Bundle | | | |
| Segare Ijiri せがれいじり | PSX | | Otameshi Disc | | SLPM 80426 | |
| Segare Ijiri せがれいじり | PSX | | Original | | SLPM 86230 | |
| Segata Sanshirou: Choujin Densetsu せがた三四郎 超人伝説 | PC | | Original | | HCJ-0346 | |
| Le Seigneur des Anneaux: Les Deux Tours | GC | | Original | | DL-DOL-GLOF-FRA | |
| Seiken Densetsu: Legend of Mana 聖剣伝説 レジェンド オブ マナ | PSX | | Original, Square Millennium Collection, PSone Books, Ultimate Hits, Sample (Asia) | | SCPS 45416 … | |
| Seikon no Joka: Hikari to Yami no Seioujo 聖痕のジョカ ~光と闇の聖王女~ | PSX | | Original | | SLPS 00483 | |
| Seima Densetsu 3x3 Eyes 聖魔伝説 3×3EYES | MCD | | Original | | G-6007, GD0004JG | |
| Seirei Senshi Spriggan 精霊戦士スプリガン | PCE | | Original | | NXCD1004 | |
| Seirei Shinseiki: Fhey Area 精霊神世紀 ~フェイエリア~ | MCD | | Original | | T-32034 | |
| Seireki 1999: Pharaoh no Fukkatsu 西暦1999 ~ファラオの復活~ | PSX | | Original | | SLPS 00599 | |
| Seiya Monogatari: Anearth Fantasy Stories 聖夜物語 | PCE | | Bundled with Book (Dengeki PC Engine Special Edition - Taikenban) | | HMD-0004 | |
| Sekigahara 関ヶ原 | FMT | | Original | | HMD-128 | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3P-EUR-B0 | |
| Sengoku Basara: Samurai Heroes | WII | | Original | | RVL-SB3E-USA-B0 | |
| Sengoku Cyber: Fujimaru Jigokuhen 戦国サイバー 藤丸地獄変 | PSX | | Original | | SCPS 10011 | |
| Sengoku Denshou 戦国伝承 | MCD | | Original | | T-24034 | |
| Sengoku Denshou ~ Sengoku 戦国伝承 | NGCD | | Original | | NGCD-017 | |
| Sengoku Kantou Sangokushi 戦国関東三国志 | PCE | | Original | | IGCD1002 | |
| Senkou no Ronde Rev.X 旋光の輪舞 リビジョンエックス | XBOX360 | | Original, Platinum Collection | | GR-2001 | |
| Sensible Soccer | MCD | | Bundled with Magazine (Playable Demo - Mega Power Disc 5, Demo) | | | |
| Sensual Angels センシャル・エンジェル | FMT | | DCCS (FM Towns Release), PC-9821 Release | | DWDC3813 | |
| Sentient: Explore the Infinite | PSX | | Original, Limited Edition | | SLES-00106 | |
| Sentinel Returns | PSX | | Original | | SLES-01051 | |
| Sento Monogatari: Sono I 「占都物語」 そのⅠ | 3DO | | Original | | FZ-SJ4054 | |
| Sentou Kokka Kai: Improved 戦闘国家-改- IMPROVED | PSX | | Original, PlayStation the Best | | SCPS 10034 … | |
| Separate Hearts 散碎的原色 | PC | | Original | | CV022 | |
| Septerra Core: Legacy of the Creator | PC | | Original | | 1CSP OR03 0020 IR | |
| Sequence Palladium シークエンス パラディウム | PC | | DigiCube, Media Kite Great Series | | DWRPM-00089, MKW-182 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 1) シークエンス・パラディウム3 ~泡沫の天地~ | PC | | Original | | KGD-04060 | |
| Sequence Palladium 3: Utakata no Ametsuchi (Disc 2) シークエンス・パラディウム3 ~泡沫の天地~ | PC | | Original | | KGD-04061 | |
| Serial Experiments Lain (Disc 1) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01603 | |
| Serial Experiments Lain (Disc 2) シリアル・エクスペリメンツ・レイン | PSX | | Original | | SLPS 01604 | |
| Serious Sam II | PC | | Original | | | |
| Serious Sam II (Disc 2) | PC | | Original | | | |
| Serious Sam II (Disc 3) | PC | | Original | | | |
| Serious Sam II (Disc 4) (Play) | PC | | Original | | | |
| Serious Sam II | XBOX | | Original | | TT-013 | |
| Sesame Street Sports | PSX | | Original | | SLUS-01180 | |
| Sesame Street: Cookie's Counting Carnival: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS4E-USA-B0 | |
| Sesame Street: Elmo's A-to-Zoo Adventure: The Videogame | WII | | Bundled with Wii Remote Cover | | RVL-SS3E-USA-B0 | |
| Sesame Street: Elmo's Letter Adventure | PSX | | Original, Twin Pack | | SLUS-00621 … | |
| Sesame Street: Elmo's Number Journey | PSX | | Original, Twin Pack | | SLUS-00622 … | |
| Sesame Street: Elmo's Reading: Preschool and Kindergarten (Disc 1) (Reading Basics) | PC | | Original | | EPK-744AE-CD1 | |
| Sesame Street: Let's Make a Word! | PC | | Original, Software for the fun of it | | KES006 | |
| Sesame Street: Numbers | MAC | | Original | | 691-0759-A, 743807A | |
| Sesame Street: Numbers | 3DO | | Original | | | |
| Sesame Street: Once Upon a Monster | XBOX360 | | Original | | WR-2060 | |
| The Settlers 7: Paths to a Kingdom | PC | | Original, Ubisoft Exclusive Think | | 300028951 | |
| The Settlers II: 10th Anniversary | PC | | Original | | 5004880 | |
| Setup Utility for DTL-H1500 (Version 1.1) | PSX | | Original | | | |
| Seven Kingdoms | PC | | Play the Games Vol. 1 | | | |
| Seven Kingdoms: Artwork | MAC | | Art Assets | | | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | MCD | | Bundled with Sega CD | | 4101 | |
| Sewer Shark | 3DO | | Original | | | |
| Sex | 3DO | | Original | | | |
| Sexy Idol Mahjong: Fashion Monogatari セクシー・アイドルま~じゃん ~ファッション物語~ | PCE | | Original | | NBCD4006 | |
| Sexy Idol Mahjong: Yakyuuken no Uta セクシー・アイドル麻雀 ~野球拳の詩~ | PCE | | Original | | NBCD4007 | |
| Sexy Parodius セクシーパロディウス | PSX | | Original | | SLPM 86009 | |
| Shachou Eiyuuden 射鵰英雄傳 | PSX | | Original | | SCPS 10139 | |
| Shadoan (Disc 1) | PC | | Original | | CD-ICD-228-0 | |
| Shadoan (Disc 2) | PC | | Original | | CD-ICD-228-1 | |
| Shadow and Shadow シャドウ アンド シャドウ | PSX | | Original | | SLPM 87027 | |
| Shadow Company: Left for Dead | PC | | Original | | | |
| Shadow Fighter | CD32 | | Original | | | |
| Shadow Madness (Disc 1) | PSX | | Original | | SCES-02099 | |
| Shadow Madness (Disc 2) | PSX | | Original | | SCES-12099 | |
| Shadow Madness | PSX | | Demo | | SLUS-90031 | |
| Shadow Man | PC | | Original | | CD194141.00-EUR | |
| Shadow Man | PC | | Covermount | | | |
| Shadow of Memories | PC | | Original | | | |
| Shadow of the Beast II: Juushin no Jubaku シャドー・オブ・ザ・ビーストⅡ ~獣神の呪縛~ | MCD | | Original | | T-60034 | |
| Shadow of the Beast II: Juushin no Jubaku シャドー・オブ・ザ・ビーストⅡ ~獣神の呪縛~ | FMT | | Original | | HMD-184 | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | FMT | | Original | | HMC-157 | |
| Shadow of the Beast: Mashou no Okite シャドー・オブ・ザ・ビースト ~魔性の掟~ | PCE | | Original | | JCCD2008 | |
| Shadow the Hedgehog | XBOX | | Original | | SE-134 | |
| Shadow the Hedgehog | GC | | Original | | DL-DOL-GUPE-USA | |
| Shadow Tower | PSX | | Original | | SLPS 01420 | |
| SHADOW Warriors シャドー・ウォリアー | 3DO | | Original | | FZ-SJ0155 | |
| SHADOW: War of Succession | 3DO | | Original | | | |
| A Shadow's Tale | WII | | Original | | RVL-SDWP-EUR-B0 | |
| ShadowCaster | PC | | CD-ROM Classics, Electronic Arts Presents | | 5393 | |
| ShadowCaster | PC | | Original | | | |
| Shadowlands | PC | | Original, 10 Pack CD-ROM Series, Action CD-ROM 5 Pak | | | |
| Shadows of the Damned | XBOX360 | | Original | | EA-2346 | |
| Shake Kids シェイクキッズ | PSX | | Original | | SLPS 01472 | |
| Shaman King: Spirit of Shamans シャーマンキング スピリットオブシャーマンズ | PSX | | Original | | SLPS 03432 | |
| Shamhat: The Holy Circlet シャムハト -The Holy Circlet- | FMT | | FM-Towns Sen'you, FM-Towns Marty Sen'you | | DWFS3010, DWFT 3012 | |
| Shamrock Spring '97 Shamrock Spring '97 Demo Disk | PC | | | | | |
| Shamrock's Fall '97 CD-ROM | PC | | | | | |
| Shanghai II 上海Ⅱ | PCE | | Original | | HCD0010 | |
| Shanghai: Große Momente | PC | | Original | | CDD-3109-04-2 | |
| Shanghai: Shouryuu Sairin 上海~昇龍再臨~ | PSX | | Original | | SLPM 86836 | |
| Shaun White Skateboarding | WII | | Original | | RVL-SHNP-EUR-B0 | |
| Shaun White Snowboarding: Road Trip | WII | | Original | | RVL-RDFP-EUR, RVL-RDFP-EUR-B1 | |
| Shaun White Snowboarding: Road Trip | WII | | Target Limited Edition | | RVL-RW7E-USA | |
| Shaun White Snowboarding: Road Trip | WII | | Original | | RVL-RDFE-USA | |
| Shaun White Snowboarding: World Stage | WII | | Original | | RVL-R6NY-EUR-B0 | |
| Sheep | PC | | Covermount, Absolute Gaming | | EI-1246 | |
| Sheep, Dog 'n' Wolf | PSX | | Original | | SLES-02895 | |
| Sheep, Dog 'n' Wolf | PC | | Kellogg's | | | |
| Sheer Delight | CD32 | | Original | | | |
| Shelley Duvall's It's a Bird's Life | 3DO | | Original | | | |
| Shellshock | PSX | | Original | | SLUS-00031 | |
| ShellShock 2: Blood Trails | XBOX360 | | Original | | SC-2021 | |
| ShellShock: Nam '67 | XBOX | | Original | | ES-019 | |
| Sheng-Hua Weiji 2 Baijinban (Leon Jingguan) 生化危机2 白金版 | PC | | Original, Sheng-Hua Weiji Xilie Daheji | | | |
| Sheng-Hua Weiji 2 Baijinban (Claire) 生化危机2 白金版 | PC | | Original, Sheng-Hua Weiji Xilie Daheji | | | |
| Sheng-Hua Weiji 3: Fuchou Nüshen 生化危机3:复仇女神 | PC | | Original, Sheng-Hua Weiji Xilie Daheji | | | |
| Shenmidao III: Fangzhu (Youxi Zhizuo Neimu) 神秘岛Ⅲ:放逐 | PC | | Original | | | |
| Shenmue II | XBOX | | Original | | MS-050 | |
| Shenmue II | XBOX | | Original | | MS-050 | |
| Shenying Tujidui 神鹰突击队 | PC | | Original | | GD94-18 | |
| Sherlock Holmes and the Hound of the Baskervilles | PC | | Collector's Edition | | 33369101US | |
| Sherlock Holmes: Consulting Detective シャーロック・ホームズの探偵講座 | FMT | | FM Towns Soft Collection Kaigai-hen Vol. 13 | | HMC-127 | |
| Sherlock Holmes: Consulting Detective | FMT | | Demonstration-ban | | HMC-901 | |
| Sherlock Holmes: Consulting Detective シャーロック・ホームズの探偵講座 | PCE | | Original | | JCCD1004 | |
| Sherlock Holmes: Consulting Detective | PCE | | Original | | TGXCD1011 | |
| Sherlock Holmes: Consulting Detective | MCD | | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | T-4501 | |
| Sherlock Holmes: Consulting Detective: Vol. I Sherlock Holmes: Consulting Detective: Vol. 1 | PC | | 5 ft. 10 PAK Vol. 2 | | | |
| Sherlock Holmes: Consulting Detective: Vol. II シャーロック・ホームズの探偵講座Ⅱ | PCE | | Original | | JCCD3012 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 1) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Consulting Detective: Vol. II (Disc 2) | MCD | | Original | | 4653 | |
| Sherlock Holmes: Das Geheimnis des silbernen Ohrrings | PC | | Software Pyramide | | | |
| Sherlock Holmes: The Mystery of the Mummy | PC | | Original, Reload / White Label | | 1564A | |
| Sherlock Holmes: The Silver Earring | WII | | Original | | RVL-SSHP-EUR-B0 | |
| Shift 2: Unleashed | PC | | Limited Edition | | 1948307 | |
| Shift 2: Unleashed | XBOX360 | | Original, Limited Edition | | EA-2356 | |
| Shikigami no Shiro 式神の城 | XBOX | | Original, Shokai Genteiban | | MP-002 | |
| Shikigami no Shiro Evolution 式神の城 EVOLUTION | XBOX | | Blue Version, Red Version | | KI-001 | |
| Shikigami no Shiro Evolution (Tokuten Data CD-ROM: Confidential) 式神の城 EVOLUTION | PC | | Ai | | Q68-00003 KI001E02 | |
| Shikyokusei (Game-Disk) 指極星 | PC | | | | KGD-0380 | |
| Shin DX Okuman Chouja Game: Tsukutte! Utte! Oomouke! 新DX億万長者ゲーム 作って! 売って! 大儲け! | PSX | | Original | | SLPM 87251 | |
| Shin Fortune Quest: Shokutaku no Kishi-tachi 新フォーチュン・クエスト ~食卓の騎士たち~ | PSX | | Gentei Special-ban | | SLPS 00381 | |
| Shin Megami Tensei 真・女神転生 | PSX | | Original | | SLPS 03170 | |
| Shin Megami Tensei If... 真・女神転生if… | PSX | | Original | | SLPM 87154 | |
| Shin Megami Tensei II 真・女神転生Ⅱ | PSX | | Original | | SLPM 86924 | |
| Shin Nihon Pro Wrestling: '94 Battlefield in Tokyo Dome 新日本プロレスリング ’94バトルフィールド in 闘強導夢 | PCE | | Original | | FCCD4001 | |
| Shin Nihon Pro Wrestling: Toukon Retsuden 新日本プロレスリング 闘魂烈伝 | PSX | | Original, PlayStation the Best | | SLPS 00084 … | |
| Shin Nihon Pro Wrestling: Toukon Retsuden 2 新日本プロレスリング 闘魂烈伝2 | PSX | | Original | | SLPS 00637 | |
| Shin Nihon Pro Wrestling: Toukon Retsuden 3 新日本プロレスリング 闘魂烈伝3 | PSX | | Original | | SLPS 01366 | |
| Shin Nihon Pro Wrestling: Toukon Retsuden 3 新日本プロレスリング 闘魂烈伝3 | PSX | | Antonio Inoki Intai Kinen Genteiban | | SLPS 01314 | |
| Shin Samurai Spirits: Haoumaru Jigokuhen ~ Samurai Shodown II 真サムライ・スピリッツ ~覇王丸地獄変~ | NGCD | | Original | | NGCD-063, NGCD-063E | |
| Shin Sangoku Musou 2 真・三國無双2 | XBOX | | Original | | KO-003 | |
| Shin Sangoku Musou 3 真・三國無双3 | XBOX | | Original | | KO-004 | |
| Shin Sangoku Musou 4 Special 真‧三國無雙4 Special | XBOX360 | | Original | | KO-2001 | |
| Shin Sangoku Musou 4 Special 真・三國無双4 Special | XBOX360 | | Original | | KO-2001 | |
| Shin Sangoku Musou 5 真‧三國無雙5 | XBOX360 | | Original | | KO-2020 | |
| Shin Sangoku Musou 5 真・三國無双5 | XBOX360 | | Original | | KO-2010 | |
| Shin Sangoku Musou 7 真‧三國無雙7 | XBOX360 | | Original | | KV-2022 | |
| Shin Sangoku Musou: Multi Raid Special 真・三國無双 MULTI RAID Special | XBOX360 | | Original | | KO-2033 | |
| Shin Sangoku Musou: Multi Raid Special 真・三國無双 MULTI RAID Special | XBOX360 | | Original | | KO-2028 | |
| Shin SD Sengokuden: Kidou Musha Taisen 新SD戦国伝 機動武者大戦 | PSX | | Genteiban | | SLPS 00576 | |
| Shin Sedai Robot Senki: Brave Saga 新世代ロボット戦記 BRAVE SAGA | PSX | | Brave Charge Box | | SLPS 01755 | |
| Shin Sedai Robot Senki: Brave Saga: Yuusha Gentei Koushiki Data Disc: Yuusha no Akashi 新世代ロボット戦記 「BRAVE SAGA」 勇者限定公式データディスク 勇者の証 | PSX | | Campaign-you Disc | | SLPM 80275 | |
| Shin Seiki Evangelion: Character Box 新世紀エヴァンゲリオン キャラクターBOX | PC | | PCHome | | 506-7036 | |
| Shin Seiki Evangelion: Eva to Yukai na Nakama-tachi 新世紀エヴァンゲリオン エヴァと愉快な仲間たち | PSX | | Original | | SLPS 01485 | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc 1) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PSX | | Original | | SLPS 01377 | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend (Disc 2) 新世紀エヴァンゲリオン 鋼鉄のガールフレンド | PSX | | Original | | SLPS 01378 | |
| Shin Shikoutei: The First Emperor 秦始皇帝 | PSX | | Original | | SCPS 45069 … | |
| Shin Super Robot Taisen 新スーパーロボット大戦 | PSX | | Original | | SLPS 00550 | |
| Shin Super Robot Taisen: Special Disc 新スーパーロボット大戦 スペシャルディスク | PSX | | Original | | SLPS 00787 | |
| Shin Theme Park 新テーマパーク | PSX | | Original | | SLPS 00810 | |
| Shining Force CD シャイニング・フォースCD | MCD | | Original | | G-6036 | |
| Shining Force CD | MCD | | Original | | 4656 | |
| Shinjuku Labyrinth 新宿ラビリンス | FMT | | Original | | FMSC0030 | |
| Shinouken ~ Ragnagard 神凰拳 | NGCD | | Original | | NGCD-218 | |
| Shinpi no Sekai El-Hazard: El-Hazard: The Magnificent World 神秘の世界エルハザード | PC-98 | | Original | | 21D-2077 | |
| The Shinri Game 2 ザ・心理ゲーム2 | PSX | | Original, Renkaban | | SLPS 00851 … | |
| The Shinri Game 3 ザ・心理ゲーム3 | PSX | | Original, Renkaban | | SLPS 01104 … | |
| The Shinri Game 7 ザ・心理ゲーム7 | PSX | | Original | | SLPS 02809 | |
| The Shinri Game 8 ザ・心理ゲーム8 | PSX | | Original | | SLPS 02946 | |
| The Shinri Game IV: Itsu mo Kokoro ni Hoshizora o ザ・心理ゲームⅣ いつも心に星空を | PSX | | Original, Renkaban | | SLPS 01670 … | |
| Shinsetsu Samurai Spirits: Bushidou Retsuden 真説サムライ・スピリッツ ~武士道烈伝~ | PSX | | Original, PlayStation the Best | | SLPM 86109 … | |
| Shinsetsu Samurai Spirits: Bushidou Retsuden 真説サムライ・スピリッツ ~武士道烈伝~ | NGCD | | Original | | NGCD-0850 | |
| Shinshuku Taisen: It's a Nony! 伸縮対戦 It’s a のに~! | PSX | | Original, Best Price | | SLPS 01114 … | |
| Shinshuku Taisen: It's a Nony! 伸縮対戦 It’s a のに~! | PSX | | Taikenban | | SLPM 80156 | |
| The Ship: Mörder Ahoi | PC | | Original | | | |
| Shiritsu Justice Gakuen: Legion of Heroes (Disc 1) (Evolution Disc) 私立ジャスティス学園 リージョン オブ ヒーローズ | PSX | | Original | | SLPS 01240 | |
| Shiritsu Justice Gakuen: Legion of Heroes (Disc 2) (Arcade Disc) 私立ジャスティス学園 リージョン オブ ヒーローズ | PSX | | Original | | SLPS 01241 | |
| Shiritsu Justice Gakuen: Nekketsu Seishun Nikki 2 私立ジャスティス学園 ~熱血青春日記2~ | PSX | | Original, CapKore | | SLPM 86750 … | |
| Shisan Zhiju 十三支局 | PC | | Original | | 917311 | |
| Shivers / Torin's Passage | PC | | | | | |
| Shock Price 500 Game Series: Black-Jack SHOCK PRICE 500 GAME SERIES ブラックジャック | PC | | Original | | SSRX 3008 | |
| Shock Price 500 Game Series: Black-Jack SHOCK PRICE 500 GAME SERIES ブラックジャック | PC | | Original | | SSRX 3008 | |
| Shock Price 500 Game Series: Chu-Chu Tataki SHOCK PRICE 500 GAME SERIES チュウチュウたたき | PC | | Original | | SSRX 3016 | |
| Shock Price 500 Game Series: Foose Ball SHOCK PRICE 500 GAME SERIES フーズボール | PC | | Original | | SRRW 52 | |
| Shock Price 500 Game Series: Golf: Challenge at Mauna Lani Resort SHOCK PRICE 500 GAME SERIES ゴルフ チャレンジ アット マウナラニリゾート | PC | | Original | | SSRX 3072 | |
| Shock Price 500 Game Series: Hanafuda SHOCK PRICE 500 GAME SERIES 花札 | PC | | Original | | SSRX 3002 | |
| Shock Price 500 Game Series: Hanafuda II SHOCK PRICE 500 GAME SERIES 花札Ⅱ | PC | | Original | | SSRX 3081 | |
| Shock Price 500 Game Series: Hit the Block SHOCK PRICE 500 GAME SERIES ヒット・ザ・ブロック | PC | | Original | | SSRX 3018 | |
| Shock Price 500 Game Series: Igo SHOCK PRICE 500 GAME SERIES 囲碁 | PC | | Original | | SSRX 3038 | |
| Shock Price 500 Game Series: Mahjong SHOCK PRICE 500 GAME SERIES 麻雀 | PC | | Original | | SSRX 3001 | |
| Shock Price 500 Game Series: Reversi SHOCK PRICE 500 GAME SERIES リバーシ | PC | | Rerelease | | SSRX 3004 | |
| Shock Price 500 Game Series: Typing Trip SHOCK PRICE 500 GAME SERIES タイピング・トリップ | PC | | | | SSRX 3051 | |
| Shock Wave | 3DO | | Original | | | |
| Shock Wave ショック・ウェーブ | 3DO | | Samples | | FZ-SD1657 | |
| Shock Wave ショックウェーブ | PSX | | Original | | SLPS 00419 | |
| Shock Wave: Operation JumpGate | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 1) | 3DO | | Original | | | |
| Shockwave 2: Beyond the Gate (Disc 2) | 3DO | | Original | | | |
| Shockwave Assault (Disc 1) (Shockwave: Invasion Earth) | PSX | | Original | | SLES-00071 | |
| Shockwave Assault (Disc 2) (Shockwave: Operation Jumpgate) | PSX | | Original | | SLES-10071 | |
| Shockwave Assault (Disc 1) (Shockwave: Invasion Earth) | PSX | | Original | | SLUS-00028 | |
| Shockwave Assault (Disc 2) (Shockwave: Operation Jumpgate) | PSX | | Original | | SLUS-00137 | |
| Shogun: Total War | PC | | Demo | | EAX08901965DD1 | |
| Shogun: Total War (Disc 2) | PC | | Original | | 798717, 1224617 | |
| Shogun: Total War: Gold Edition | PC | | Green Pepper, Total War: Eras | | DIS-TWESHOG, SEGA-PC097-R | |
| Shonen Jump's One Piece: Grand Battle | PSX | | Original | | SLES-03807 … | |
| Shoot 7 Shoot Games | PSX | | Original | | SLES-04176 … | |
| Shopmania | PC | | Original | | P/N 61227-CD | |
| Short Warp: Warp's Short Game Collection ショート・ワープ | 3DO | | Original | | FZ-SJ2357 | |
| Shougi no Tatsujin: Master of Syougi 将棋の達人 | NGCD | | Original | | ADCD-010 | |
| Shouhuzhe Zhi Jian (Disc 1) 守护者之剑 | PC | | Original | | | |
| Shouhuzhe Zhi Jian (Disc 2) 守护者之剑 | PC | | Original | | | |
| The Show | PC | | Original | | | |
| Showcase 2000/01 Codemasters PC Demo: New Titles: November 2000 | PC | | Demo | | CLED 0003, MBETCD2200 | |
| Showdown: Legends of Wrestling | XBOX | | Original | | AC-029 | |
| Showtime Championship Boxing | WII | | Original | | RVL-RSYP-EUR | |
| Shpionskie igry (Disc 1) Шпионские игры | PC | | Original | | | |
| Shpionskie igry (Disc 2) Шпионские игры | PC | | Original | | | |
| Shrek 2 | PC | | Original | | 32585.101.UK | |
| Shrek 2 | GC | | Original, Player's Choice | | DL-DOL-G3RF-FRA | |
| Shrek 2 | GC | | Original, Player's Choice | | DL-DOL-G3RD-NOE | |
| Shrek 2 Шрек 2 | PC | | 1C: Kollekciya igrushek | | | |
| Shrek 2 | GC | | Original, Player's Choice | | DL-DOL-G3RE-USA, DL-DOL-G3RE-USA-02 | |
| Shrek 2 シュレック 2 | XBOX | | Original, World Collection | | AV-055 | |
| Shrek 2 Activity Centre: Twisted Fairy Tale Fun | PC | | Original | | 31917.101.AU | |
| Shrek 2: CD-ROM Multimedialny | PC | | | | | |
| Shrek the Third: The Search for Arthur | VFLASH | | Original | | 093140(US) | |
| Shrek Treasure Hunt | PSX | | Original | | SLUS-01463 | |
| Shuangxing Wuyu 双星物语 | PC | | Original | | | |
| Shutokou Battle Gaiden: Super Technic Challenge: Drift King e no Michi 首都高バトル外伝 スーパーテクニックチャレンジ ~ドリフトキングへの道~ | PSX | | Original | | SLPS 00573 | |
| Shutokou Battle R 首都高バトルR | PSX | | Highlight-ban | | SLPM 80088 | |
| Shutokou Battle R 首都高バトルR | PSX | | Original, PlayStation the Best, PSone Books | | SLPS 00828 … | |
| Shuukan Pro Wres Kanshuu: Pro Wres Sengokuden 週刊プロレス監修 プロレス戦国伝 | PSX | | Original | | SLPS 00881 | |
| Sibir': Zolotoe izdanie Сибирь: Золотое издание | PC | | Original | | | |
| Sid Meier's Alpha Centauri | PC | | Original | | ORG08901524D | |
| Sid Meier's C.P.U. Bach | 3DO | | Original | | | |
| Sid Meier's Civilization II: Fantastic Worlds | PC | | Original | | 0-529-47-101 | |
| Sid Meier's Civilization III (Bonus CD) | PC | | Game of the Year Edition | | Part # 24356CD2 | |
| Sid Meier's Civilization III Complete (Disc 2) | PC | | Sid Meier's Civilization Chronicles, Green Pepper | | 51989/CD4 | |
| Sid Meier's Civilization III Complete (Disc 3) | PC | | Sid Meier's Civilization Chronicles, Green Pepper | | 51989/CD5 | |
| Sid Meier's Civilization III Complete (Disc 1) (Install/Play) | PC | | Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.3 | |
| Sid Meier's Civilization III Complete (Disc 2) (Play the World) | PC | | PC Gamer Presents, Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.4 | |
| Sid Meier's Civilization III Complete (Disc 3) (Conquests) | PC | | PC Gamer Presents, Rerelease, Sid Meier's Civilization Chronicles | | 31074-1.5 | |
| Sid Meier's Civilization III: Fan Kit | PC | | Deluxe Edition | | 1011794, CIV3CEPCFGDI/A2 | |
| Sid Meier's Civilization IV | PC | | Original | | | |
| Sid Meier's Civilization IV | PC | | 1C: Kollekciya igrushek | | | |
| Sid Meier's Civilization IV (Disc 1) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.6 | |
| Sid Meier's Civilization IV (Disc 1) (Install) | PC | | Original | | | |
| Sid Meier's Civilization IV (Disc 2) | PC | | Original, Sid Meier's Civilization Chronicles | | 31074-1.7 | |
| Sid Meier's Civilization IV (Disc 2) (Play) | PC | | Original | | | |
| Sid Meier's Civilization IV: Complete | PC | | Original | | | |
| Sid Meier's Civilization IV: Ultimate (Disc 1) | PC | | Original, Collectors Edition | | 5052955/DVD | |
| Sid Meier's Civilization Revolution | XBOX360 | | Original | | TT-2021 | |
| Sid Meier's Civilization V | PC | | Original | | 5055802/DVD | |
| Sid Meier's Civilization V | PC | | Original, Special Edition | | 31817-1 | |
| Sid Meier's Civilization V | MAC | | Original | | 12350-1DDA | |
| Sid Meier's Civilization V: Brave New World Sid Meier's Civilization V: Дивный новый мир | PC | | Original | | 5061834/DVD | |
| Sid Meier's Civilization V: Gold Edition | PC | | Original | | 41252-1 | |
| Sid Meier's Civilization: Shin Sekai Shichidai Bunmei シヴィライゼーション ~新・世界七大文明~ | PSX | | Original | | SLPS 00336 | |
| Sid Meier's Gettysburg! | PC | | CD-ROM Classics | | 1187707 | |
| Sid Meier's Pirates! | XBOX | | Original | | TT-143 | |
| Sid Meier's Pirates! Bonus DVD | PC | | PC Game Bundle | | PIRATES GB/F/D/E/I | |
| Side by Side Special サイドバイサイドスペシャル | PSX | | Original | | SLPS 01175 | |
| Side by Side Special サイドバイサイドスペシャル | PSX | | Taikenban | | SLPM 80145 | |
| Side Pocket 3 サイド・ポケット3 | PSX | | Original | | SLPS 01079 | |
| Sidewinder サイドワインダー | PSX | | Original | | SLPS 00156 | |
| Sidewinder 2: Let's Dance in the Sky サイドワインダー2 | PSX | | Original, PlayStation the Best | | SLPS 00954 … | |
| Sidewinder USA サイドワインダーUSA | PSX | | PlayStation the Best | | SLPS 91010 | |
| Die Siedler III (Disc 1) | PC | | Purple Hills | | | |
| Die Siedler III (Disc 2) | PC | | Purple Hills | | | |
| Die Siedler IV | PC | | Green Pepper, Software Pyramide | | | |
| Die Siedler: Platin Editon I • II • III • IV (Disc 2) | PC | | Platin Edition | | | |
| Sierra Pro Pilot (Disc 2) (Lezioni a Terra) | PC | | Covermount | | S0013017 | |
| Sign of the Sun | PC | | | | | |
| Silent Bomber | PSX | | Original | | SLUS-00902 | |
| Silent Hill | PSX | | Demo | | SLED-01735 | |
| Silent Hill | PSX | | Original, Platinum | | SLES-01514 … | |
| Silent Hill | PSX | | Demo | | SLED-01774 | |
| Silent Hill サイレントヒル | PSX | | Original | | SLPM 86192 | |
| Silent Hill サイレントヒル | PSX | | Trial Version | | SLPM 80363 | |
| Silent Hill | PSX | | Trade Demo | | SLUS-80707 | |
| Silent Hill | PSX | | Demo | | SLUS-90050 | |