Region | Title | System | Version | Edition | Languages | Serial | Status |
| Drome Racers | GC | | Original | | DL-DOL-GD9E-USA | |
| Driven | GC | | Original | | DL-DOL-GDVP-EUR | |
| DreamWorks Shrek: SuperSlam | GC | | Original | | DL-DOL-G3YX-EUR | |
| DreamWorks Shark Tale | GC | | Original | | DL-DOL-G9TP-UKV | |
| DreamWorks Over the Hedge | GC | | Original | | DL-DOL-GH5E-USA | |
| DreamWorks Madagascar | GC | Rev 1 | Original | | DL-DOL-GGZE-USA, DL-DOL-GGZE-USA-01 | |
| DreamWorks Madagascar | GC | | Original | | DL-DOL-GGZS-ESP | |
| DreamWorks Grosse Haie: Kleine Fische | GC | | Original | | DL-DOL-G9TD-NOE | |
| DreamWorks Ab durch die Hecke | GC | | Original | | DL-DOL-GH5D-NOE | |
| DreamWorks & Aardman Flushed Away | GC | | Original | | DL-DOL-GLHE-USA | |
| Dragon's Lair 3D: Special Edition | GC | | Original | | DL-DOL-GDGP-EUR, DL-DOL-GDGP-NOE | |
| Dragon Ball Z: Sagas | GC | | Original | | DL-DOL-GZEE-USA | |
| Dragon Ball Z: Budokai 2 | GC | | Original | | DL-DOL-GZ3E-USA | |
| Dragon Ball Z: Budokai 2 | GC | | Original | | DL-DOL-GZ3P-EUR | |
| Dragon Ball Z: Budokai | GC | | Original, Player's Choice | | DL-DOL-GD7E-USA, DL-DOL-GD7E-USA-01 | |
| Dr. Muto | GC | | Original | | DL-DOL-GMUE-USA | |
| Doubutsu no Mori e+ どうぶつの森e+ | GC | | Original, e-Reader+ Bundle | | DL-DOL-GAEJ-JPN | |
| Doubutsu no Mori + どうぶつの森+ | GC | Rev 1 | Original | | DL-DOL-GAFJ-JPN | |
| Doubutsu no Mori + どうぶつの森+ | GC | | Original | | DL-DOL-GAFJ-JPN | |
| Doshin the Giant | GC | | Original | | DL-DOL-GKDP-EUR | |
| Donkey Konga 3: Tabehoudai! Haru Mogitate 50-kyoku ドンキーコンガ3 食べ放題!春もぎたて50曲 | GC | | Original | | DL-DOL-GY3J-JPN | |
| Donkey Konga 2: Hit Song Parade ドンキーコンガ2 ヒットソングパレード | GC | | Original | | DL-DOL-GY2J-JPN | |
| Donkey Konga 2 | GC | | Original | | DL-DOL-GY2E-USA | |
| Donkey Konga 2 | GC | | Original | | DL-DOL-GY2P-EUR | |
| Donkey Konga | GC | | Original, DK Bongos Controller Bundle | | DL-DOL-GKGE-USA | |
| Donkey Konga ドンキーコンガ | GC | | Bundled with Taru Konga Controller | | DL-DOL-GKGJ-JPN | |
| Donkey Konga | GC | | Original | | DL-DOL-GKGP-EUR | |
| Donkey Kong Jungle Beat | GC | | Original | | DL-DOL-GYBE-USA | |
| Donkey Kong Jungle Beat ドンキーコング ジャングルビート | GC | | Original | | DL-DOL-GYBJ-JPN | |
| Donkey Kong Jungle Beat | GC | | Original, Bundled with DK Bongos | | DL-DOL-GYBP-EUR | |
| Disney/Pixar The Incredibles: Rise of the Underminer | GC | | Original | | DL-DOL-GIQE-USA | |
| Disney/Pixar The Incredibles: Rise of the Underminer | GC | | Original | | DL-DOL-GIQX-EUU | |
| Disney/Pixar The Incredibles | GC | | Original, Player's Choice | | DL-DOL-GICP-ESP, DL-DOL-GICP-EUR, DL-DOL-GICP-UKV | |
| Disney/Pixar Ratatouille | GC | | Original | | DL-DOL-GLLE-USA | |
| Disney/Pixar Ratatouille | GC | | Original | | DL-DOL-GLLF-FRA | |
| Disney/Pixar Les Indestructibles | GC | | Original | | DL-DOL-GICF-FRA | |
| Disney/Pixar Le Monde de Nemo | GC | | Original | | DL-DOL-GNEF-FRA | |
| Disney/Pixar Finding Nemo | GC | | Original, Player's Choice | | DL-DOL-GNEP-UKV | |
| Disney/Pixar Findet Nemo Disney/Pixar Finding Nemo | GC | | Original | | DL-DOL-GNED-NOE | |
| Disney/Pixar Cars | GC | | Original | | DL-DOL-GKJE-USA | |
| Disney/Pixar Cars | GC | | Original | | DL-DOL-GKJP-EUR | |
| Disney/Pixar Buscando a Nemo Disney/Pixar Finding Nemo | GC | | Original | | DL-DOL-GNES-ESP | |
| Disney's Winnie the Pooh's Rumbly Tumbly Adventure | GC | | Original | | DL-DOL-GWHP-EUR | |
| Disney's The Haunted Mansion | GC | | Original | | DL-DOL-GHYE-USA | |
| Disney's Piglet's Big Game | GC | | Original | | DL-DOL-GPLP-UKV | |
| Disney's Mickey Mouse no Fushigi na Kagami ディズニーのミッキーマウスの不思議な鏡 | GC | Rev 1 | Original | | DL-DOL-GDMJ-JPN | |
| Disney's Magical Mirror Starring Mickey Mouse | GC | | Original | | DL-DOL-GDMP-EUR | |
| Disney's Hide & Sneak | GC | | Original | | DL-DOL-GHVP-EUR, DL-DOL-GHVP-NOE | |
| Disney's Extreme Skate Adventure | GC | | Original | | DL-DOL-GEXE-USA | |
| Disney's Donald Duck: Quack Attack | GC | | Original | | DL-DOL-GDDP-EUR | |
| Disney's Donald Duck PK Disney's Donald Duck: Phantomias: Platyrhynchos Kineticus | GC | | Original | | DL-DOL-GDOP-EUR | |
| Disney's Chicken Little | GC | | Original | | DL-DOL-GHCP-UKV | |
| Disney Sports: Soccer ディズニースポーツ:サッカー | GC | | Original | | DL-DOL-GDKJ-JPN | |
| Disney Sports: Football | GC | | Original | | DL-DOL-GDKP-EUR | |
| Digimon Rumble Arena 2 | GC | | Original | | DL-DOL-GD6P-EUR | |
| Die Hard: Vendetta | GC | | Original | | DL-DOL-GDIE-USA | |
| Die Hard: Vendetta | GC | | Original | | DL-DOL-GDIY-EUU | |
| Die Hard: Vendetta | GC | | Original | | DL-DOL-GDIP-EUR | |
| Densetsu no Quiz-ou Kettei-sen 伝説のクイズ王決定戦 | GC | | Original | | DL-DOL-GQZJ-JPN | |
| Defender | GC | | Original | | DL-DOL-GDFE-USA | |
| Def Jam: Vendetta | GC | | Original | | DL-DOL-GDTP-NOE, DL-DOL-GDTP-UKV | |
| Def Jam: Fight for NY | GC | | Original | | DL-DOL-GNWP-EUR, DL-DOL-GNWP-NOE | |
| Dave Mirra Freestyle BMX 2 | GC | | Original, Player's Choice | | DL-DOL-GBXE-USA | |
| Dave Mirra Freestyle BMX 2 | GC | | Original | | DL-DOL-GBXP-EUR | |
| Darkened Skye | GC | | Original | | DL-DOL-GDQP-EUR-01 | |
| Dark Summit | GC | | Original | | DL-DOL-GDSE-USA | |
| Dark Summit | GC | | Original | | DL-DOL-GDSP-EUR | |
| Dancing Stage Mario Mix | GC | | Bundled with Dance Pad | | DL-DOL-GWZP-EUR | |
| Dance Dance Revolution: Mario Mix | GC | Rev 1 | Bundled with Dance Pad | | DL-DOL-GWZE-USA | |
| Dance Dance Revolution with Mario ダンスダンスレボリューション ウィズ マリオ | GC | | Original | | DL-DOL-GWZJ-JPN | |
| Dairantou Smash Brothers DX 大乱闘スマッシュブラザーズDX | GC | | Original | | DL-DOL-GALJ-JPN | |
| Duel Masters: Nettou! Battle Arena デュエル・マスターズ 熱闘!バトルアリーナ | GC | | Original | | DL-DOL-GDUJ-JPN | |
| Drome Racers | GC | | Original | | DL-DOL-GD9P-NOE | |
| Driven | GC | | Beta | | | |
| Driven | GC | | Original | | DL-DOL-GDVE-USA | |
| DreamWorks Shrek: SuperSlam | GC | | Original | | DL-DOL-G2RE-USA | |
| DreamWorks Shrek: SuperSlam | GC | | Original | | DL-DOL-G3YY-EUU | |
| DreamWorks Shrek: SuperSlam | GC | | Original | | DL-DOL-G3YP-UKV | |
| DreamWorks Shrek: Smash n' Crash Racing | GC | | Original | | DL-DOL-G4IE-USA | |
| DreamWorks Shrek: Smash n' Crash Racing | GC | | Original | | DL-DOL-G4IP-EUR | |
| DreamWorks Shark Tale | GC | | Original | | DL-DOL-G9TE-USA | |
| DreamWorks Shark Tale DreamWorks シャーク・テイル | GC | | Original | | DL-DOL-G9TJ-JPN | |
| DreamWorks Shark Tale | GC | | Original | | DL-DOL-G9TI-ITA | |
| DreamWorks Over the Hedge | GC | | Original | | DL-DOL-GH5P-UKV | |
| DreamWorks Nos Voisins, les Hommes | GC | | Original | | DL-DOL-GH5F-FRA | |
| DreamWorks Madagascar | GC | | Original | | DL-DOL-GGZP-UKV | |
| DreamWorks Madagascar | GC | | Original | | DL-DOL-GGZH-HOL | |
| DreamWorks Madagascar マダガスカル | GC | | Original | | DL-DOL-GGZJ-JPN | |
| DreamWorks Madagascar | GC | | Original | | DL-DOL-GGZI-ITA | |
| DreamWorks Madagascar | GC | | Original | | DL-DOL-GGZX-NOE | |
| DreamWorks Gang de Requins | GC | | Original | | DL-DOL-G9TF-FRA | |
| DreamWorks & Aardman Flushed Away | GC | | Original | | DL-DOL-GLHP-EUR | |
| Dream Mix TV: World Fighters ドリームミックスTV ワールドファイターズ | GC | | Original | | DL-DOL-GKWJ-JPN | |
| Dragon's Lair 3D: Return to the Lair | GC | | Original | | DL-DOL-GDGE-USA | |
| Dragon Drive: D-Masters Shot ドラゴンドライブ ディマスターズショット | GC | | Original | | DL-DOL-GD5J-JPN | |
| Dragon Drive: D-Masters Shot (Anime Disc) ドラゴンドライブ ディマスターズショット | GC | | Original | | DL-DOL-PD5J-JPN | |
| Dragon Ball Z: Budokai | GC | | Player's Choice | | DL-DOL-GD7P-EUR | |
| Dragon Ball Z ドラゴンボールZ | GC | | Original | | DL-DOL-GZBJ-JPN | |
| Doubutsu no Mori e+ どうぶつの森e+ | GC | Rev 1 | Original | | DL-DOL-GAEJ-JPN | |
| Doubutsu Banchou 動物番長 (ドーブツ バンチョー) | GC | | Original | | DL-DOL-GDBJ-JPN | |
| Doraemon: Minna de Asobou! Miniland ドラえもん みんなで遊ぼう!ミニドランド | GC | | Original | | DL-DOL-GDAJ-JPN | |
| Dokapon DX: Wataru Sekai wa Oni Darake ドカポンDX わたる世界はオニだらけ | GC | | Original | | DL-DOL-GDNJ-JPN | |
| Disneys Himmel und Huhn | GC | | Original | | DL-DOL-GHCD-NOE | |
| Disneys Ferkels grosses Abenteuer-Spiel | GC | | Original | | DL-DOL-GPLD-NOE | |
| Disney/Pixar The Incredibles: Rise of the Underminer | GC | | Original | | DL-DOL-GIQY-EUR | |
| Disney/Pixar The Incredibles | GC | | Original | | DL-DOL-GICE-USA | |
| Disney/Pixar The Incredibles | GC | | Original | | DL-DOL-GICH-HOL | |
| Disney/Pixar Nemo-reul Chajaseo 니모를 찾아서 | GC | | Original | | DL-DOL-GNEK-KOR | |
| Disney/Pixar Mr. Incredible: Kyouteki Underminer Toujou Mr.インクレディブル 強敵アンダーマイナー登場 | GC | | Original | | DL-DOL-GIQJ-JPN | |
| Disney/Pixar Mr. Incredible Mr.インクレディブル | GC | | Original | | DL-DOL-GICJ-JPN | |
| Disney/Pixar Monsters, Inc.: Scream Arena | GC | | Original | | DL-DOL-GMNE-USA | |
| Disney/Pixar Monsters, Inc.: Scream Arena | GC | | Original | | DL-DOL-GMNP-EUR | |
| Disney/Pixar Finding Nemo | GC | Rev 1 | Original | | DL-DOL-GNEE-USA | |
| Disney/Pixar Finding Nemo | GC | | Original | | DL-DOL-GNEE-USA | |
| Disney/Pixar Finding Nemo ファインディング・ニモ | GC | | Original | | DL-DOL-GFNJ-JPN | |
| Disney/Pixar Die Unglaublichen | GC | | Original | | DL-DOL-GICD-NOE | |
| Disney/Pixar Cars | GC | | Original | | DL-DOL-GKJS-ESP | |
| Disney/Pixar Cars | GC | | Original | | DL-DOL-GKJH-HOL | |
| Disney/Pixar Cars カーズ | GC | | Original | | DL-DOL-GKJJ-JPN | |
| Disney/Pixar Cars | GC | | Original | | DL-DOL-GKJD-NOE | |
| Disney/Pixar Cars Disney/Pixar Cars Quatre Roues | GC | | Original | | DL-DOL-GKJF-FRA | |
| Disney's Winnie the Pooh's Rumbly Tumbly Adventure | GC | | Original | | DL-DOL-GWHE-USA | |
| Disney's Tarzan: Untamed | GC | | Original | | DL-DOL-GTZE-USA | |
| Disney's Tarzan: Freeride | GC | | Original | | DL-DOL-GTZP-EUR | |
| Disney's PK: Out of the Shadows | GC | | Original | | DL-DOL-GPKE-USA | |
| Disney's Piglet's Big Game | GC | | Original | | DL-DOL-GPLE-USA | |
| Disney's Party | GC | | Original | | DL-DOL-GMTE-USA | |
| Disney's Party | GC | | Original | | DL-DOL-GMTP-NOE | |
| Disney's Mickey to Minnie Trick & Chase ディズニーのミッキー&ミニー トリック&チェイス | GC | | Original | | DL-DOL-GAAJ-JPN | |
| Disney's Magical Park ディズニーのマジカルパーク | GC | | Original | | DL-DOL-GMTJ-JPN | |
| Disney's Magical Park ディズニーのマジカルパーク | GC | | Jitsuen-you Sample | | DL-DOL-DMTJ-DIS | |
| Disney's Magical Mirror Starring Mickey Mouse | GC | | Original | | DL-DOL-GDME-USA | |
| Disney's Hide & Sneak | GC | Rev 1 | Original | | DL-DOL-GHVE-USA | |
| Disney's Extreme Skate Adventure | GC | | Original | | DL-DOL-GEXY-EUR | |
| Disney's Extreme Skate Adventure | GC | | Original | | DL-DOL-GEXX-EUR | |
| Disney's Extreme Skate Adventure | GC | | Original | | DL-DOL-GEXP-UKV | |
| Disney's Donald Duck: Goin' Quackers | GC | | Original | | DL-DOL-GDDE-USA | |
| Disney's Chicken Little | GC | | Original | | DL-DOL-GHCE-USA | |
| Disney's Chicken Little チキン·リトル | GC | | Original | | DL-DOL-GHCJ-JPN | |
| Disney Sports: Soccer | GC | | Original | | DL-DOL-GDKE-USA | |
| Disney Sports: Skateboarding | GC | | Original | | DL-DOL-GDXE-USA | |
| Disney Sports: Skateboarding ディズニースポーツ:スケートボーディング | GC | | Original | | DL-DOL-GDXJ-JPN | |
| Disney Sports: Skateboarding | GC | | Original | | DL-DOL-GDXP-EUR | |
| Disney Sports: Football | GC | | Original | | DL-DOL-GDWE-USA | |
| Disney Sports: Basketball | GC | | Original | | DL-DOL-GDLE-USA | |
| Disney Sports: Basketball ディズニー スポーツ: バスケットボール | GC | | Original | | DL-DOL-GDLJ-JPN | |
| Disney Sports: Basketball | GC | | Original | | DL-DOL-GDLP-EUR | |
| Disney Sports: American Football ディズニー スポーツ: アメリカン フットボール | GC | | Original | | DL-DOL-GDWJ-JPN | |
| Disney Les Aventures de Porcinet | GC | | Original | | DL-DOL-GPLF-FRA | |
| Disney Chicken Little | GC | | Original | | DL-DOL-GHCF-FRA | |
| Dinotopia: The Sunstone Odyssey | GC | | Original | | DL-DOL-GD4E-USA | |
| Digimon World X デジモン ワールド X | GC | | Original | | DL-DOL-GDJJ-JPN | |
| Digimon World 4 | GC | | Original | | DL-DOL-GDJE-USA | |
| Digimon Rumble Arena 2 | GC | | Original | | DL-DOL-GD6E-USA | |
| Digimon Battle Chronicle デジモンバトルクロニクル | GC | | Original | | DL-DOL-G2DJ-JPN | |
| Die Hard: Vendetta | GC | | Original | | DL-DOL-GDIX-EUB | |
| Les Désastreuses Aventures des Orphelins Baudelaire: D'Apres Lemony Snicket | GC | | Original | | DL-DOL-GLCF-FRA | |
| Defender: For All Mankind | GC | | Original | | DL-DOL-GDFP-EUR | |
| Def Jam: Vendetta | GC | | Original | | DL-DOL-GDTE-USA | |
| Def Jam: Fight for NY | GC | | Original | | DL-DOL-GNWE-USA | |
| Dead to Rights | GC | | Original | | DL-DOL-GDRE-USA | |
| Dead to Rights | GC | | Original | | DL-DOL-GDRP-EUR | |
| Darkened Skye | GC | | Original | | DL-DOL-GDQE-USA | |
| Dakar 2: The World's Ultimate Rally | GC | | Original | | DL-DOL-GPDE-USA | |
| Dakar 2 | GC | | Original | | DL-DOL-GPDP-EUR | |
| Dairantou Smash Brothers DX 大乱闘スマッシュブラザーズDX | GC | Rev 2 | Original | | DL-DOL-GALJ-JPN | |
| Dairantou Smash Brothers DX 大乱闘スマッシュブラザーズDX | GC | Rev 1 | Original | | DL-DOL-GALJ-JPN | |
| Dairantou Smash Brothers DX 大乱闘スマッシュブラザーズDX | GC | | Taikenban | | DL-DOL-DALJ-DIS | |
| Dabi Tsuku 3: Derby-ba o Tsukurou! ダビつく3 ダービー馬をつくろう! | GC | | Original | | DL-DOL-G3TJ-JPN | |