Region | Title | System | Version | Edition | Languages | Serial | Status |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | | |
| The San Diego Zoo Presents... The Animals! | PC | Version 2 PB | Original | | 170121 | |
| The San Diego Zoo Presents... The Animals! | MAC | Version 1 | Bundle Version OEM | | | |
| SWIV 3D (Playable Demo) | PC | v5.25 | | | | |
| The Sting! | PC | v2.0e | Original | | ROTHESTING0004USLAB | |
| Sophie's World | PC | UK Version 1.0 | Original | | | |
| Syberia | PC | SSV1.0 | Demo | | DEM379CD | |
| Susume! Taisen Puzzle-dama 進め!対戦ぱずるだま | KSGV | Rev A | Original | | GV027-J1 | |
| Space Shuttle The Software Toolworks Presents... Space Shuttle | PC | Rev A | Bundle Version OEM | | RVL 13-004-073 | |
| Shougaku Ongaku (5·6-nensei-you) 小学音楽(5·6年生用) | FMT | Rev A | Original | | HMB-512A | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPX-SCN-B2 | |
| Skylanders: Spyro's Adventure | WII | Rev 3 | Starter Pack | | RVL-SSPP-EUR-B2 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPX-SCN-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 2 | Starter Pack | | RVL-SSPP-EUR-B1 | |
| Super Paper Mario スーパーペーパーマリオ | WII | Rev 1 | Original | | RVL-R8PJ-JPN | |
| SRS: Street Racing Syndicate | GC | Rev 1 | Original | | DL-DOL-GCSP-EUR | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8E-USA-B1 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8I-EUZ-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8P-EUR-B0 | |
| Skylanders: Trap Team | WII | Rev 1 | Starter Pack | | RVL-SK8D-FAH-B0 | |
| Skylanders: Swap Force | WII | Rev 1 | Starter Pack | | RVL-SVXE-USA-B1 | |
| Skylanders: Swap Force | WII | Rev 1 | Starter Pack | | RVL-SVXP-EUR-B0 | |
| Skylanders: Swap Force | WII | Rev 1 | Starter Pack | | RVL-SVXI-EUZ-B0 | |
| Skylanders: Swap Force | WII | Rev 1 | Starter Pack | | RVL-SVXF-FAH-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPE-USA-B1 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPX-SCN-B0 | |
| Skylanders: Spyro's Adventure | WII | Rev 1 | Starter Pack | | RVL-SSPP-EUR-B0 | |
| Sewer Shark | MCD | Rev 1 | Original | | T-6201 | |
| Serious Sam: Next Encounter | GC | Rev 1 | Original | | DL-DOL-G3BE-USA | |
| Scooby-Doo! Ancient Adventure | VFLASH | Rev 1 | Original | | 093080(US) | |
| Sid Meier's Alpha Centauri | MAC | RELEASE 4.0 | Original | | | |
| Socket Low Power SDIO WLAN | PPC | Release 142 D | Original | | P/N 6210-00142 D | |
| SocketScan | PALM | Release 108K | Original | | P/N 6210-00108 K | |
| Super Street Fighter II Turbo | 3DO | RE2 | Original | | FZ-SM3851 | |
| Sol-Feace | MCD | RE2 | Bundled with Sega CD | | 4130 | |
| Sol-Feace | MCD | RE | Bundled with Sega CD | | 4130 | |
| Salvat Enciclopedia Interactiva: Nueva Versión '98 | CDI | L.01.01 | Original | | | |
| The Soft Rock Software Collection | ARCH | Edition 1 | Original | | | |
| Shin-ou Densetsu Crystania DX 神王伝説クリスタニアDX | PC-98 | CDX-V1.00 | Original | | 001J291TA | |
| Starship Tycoon | PC | Build 2.24 | Original | | | |
| Space Hulk: Vengeance of the Blood Angels | 3DO | Beta 8 | Beta (CD-R) | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 3) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 2) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Star Wars Galaxies: An Empire Divided (Disc 1) | PC | Beta 3 | Beta | | | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | Beta | | | | |
| Super DubluClic Galactic: NTSF: Joc de Cultura Generala Matematica Super DubluClic Galactic: NTSF: Joc de Cultură Generală Matematică | PC | 9.0.0.383 | Original | | RNPC S5002396 5552 | |
| Sinkha 1: Hyleyn | PC | 8.5.0.321 | Original | | | |
| Sinkha 1: Hyleyn | PC | 8.5.0.321 | Original | | | |
| Sega Network Taisen Mahjong MJ4 セガネットワーク対戦麻雀MJ4 | LINDBERGH | 8.003 | Lindbergh Red EX | | DVP-0049G | |
| Sega Network Taisen Mahjong MJ4 セガネットワーク対戦麻雀MJ4 | LINDBERGH | 7.000 | Lindbergh Red EX | | DVP-0049F | |
| The Sims 3: Outdoor Living Stuff | PC | 7.0.55.010001 | Original | | MXX09207588D | |
| The Sims 3: Late Night (Expansion Pack) | PC | 6.0.81.009001 | Original | | MXX09207582D | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 5.1 | 5 ft. 10 PAK Vol. 2 | | CD 7012 SPI | |
| StarHorse 2: Final Destination | LINDBERGH | 5.000 | Lindbergh StarHorse 2 | | DVP-0086D | |
| Sega Network Taisen Mahjong MJ3 セガ・ネットワーク対戦麻雀MJ3 | CHIHIRO | 5.000 | Original | | GDX-0017D | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 5.000 | Original | | GDX-0006D | |
| Sid Meier's Civilization | PC | 474.03 | Rerelease | | MP 190128D01R | |
| Sega Network Taisen Mahjong MJ2 セガ・ネットワーク対戦麻雀MJ2 | CHIHIRO | 4.000 | Original | | GDX-0006C | |
| StormC 4 | ACD | 4 | Original | | | |
| Sherlock Holmes: Consulting Detective: Vol. III | PC | 4 | Original | | CDRM1061930 | |
| StepMania | PC | 3.9 rc2a | Dance Pad Bundle | | | |
| SispriGauntlet シスプリガントレット | PC | 3.5.2.10 | Original | | SPG-C7200 | |
| Sid Meier's Colonization Sid Meier's Colonization: Create a New Nation | PC | 3.141592 | Rerelease | | P/N 70119 | |
| Swap Magic 3 | PS2 | 3.10 (American) | Unlicensed | | | |
| Sesame Street: Elmo's Preschool (Disc 2) (Search & Learn Adventures) | PC | 3.1 | Original | | P/N 379663-CD2 | |
| Sesame Street: Elmo's Preschool (Disc 1) (Elmo's Preschool) | PC | 3.1 | Original | | P/N 379663-CD1 | |
| Self Selling Disc | CDI | 3.1 | | | 310-690-049-2 | |
| Self Selling Disc | CDI | 3.1 | | | | |
| Sentimental Graffiti 2: Third Window センチメンタルグラフティ2 サードウィンドウ | DC | 3.000 | Hibaihin | | 610-7749 | |
| Storybook Weaver Deluxe 2004 | PC | 3.0 | Original | | 483050-CD | |
| Sid Meier's Alpha Centauri: Planetary Pack | PC | 3.0 | Original | | | |
| Shisenfuu Gekikara Mahjong 四川風激辛麻雀 | PC | 3.0 | Original | | | |
| Sherlock Holmes: Consulting Detective: Vol. III | MAC | 3.0 | | | CDRM 835400 | |
| Sesame Street Toddler: Elmo's Art Workshop (Disc 2) | PC | 3.0 | Rerelease | | STL744AE-CD2 | |
| Scooby-Doo 2: Monsters Unleashed | PC | 3.0 | Original | | | |
| Sammy's Science House | PC | 3.0 | Southwestern Kids' Collection | | R2522/8612a.7.01 | |
| Shengui Yuyan: Shiluo Zhi Zhang (Disc 4) 神鬼寓言:失落之章 | PC | 25.7.13.149 | Original | | 0905 Part No. X11-42718 | |
| Shengui Yuyan: Shiluo Zhi Zhang (Disc 3) 神鬼寓言:失落之章 | PC | 25.7.13.149 | Original | | 0905 Part No. X11-42716 | |
| Shengui Yuyan: Shiluo Zhi Zhang (Disc 2) 神鬼寓言:失落之章 | PC | 25.7.13.149 | Original | | 0905 Part No. X11-42714 | |
| Shengui Yuyan: Shiluo Zhi Zhang (Disc 1) 神鬼寓言:失落之章 | PC | 25.7.13.149 | Original | | 0905 Part No. X11-42711 | |
| Suguri スグリ | PC | 2005 8 / 9 | Trial Edition | | | |
| Stars! | PC | 2.7a | Original | | EI-1036 | |
| Sid Meier's Civilization II Scenarios: Conflicts in Civilization | PC | 2.62 | Original | | 0-520-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Infogrames Rerelease | | | |
| Sid Meier's Civilization II | PC | 2.42a | Rerelease | | 0-492-47-101 | |
| Sid Meier's Civilization II | PC | 2.42a | Top 10 Games | | CD-C95-963-BS-E | |
| Sid Meier's Civilization II | PC | 2.42 | Rerelease | | 0-492-47-101 | |
| The Settlers IV: Trojanie i Eliksir Mocy | PC | 2.4.1090.0 | Original | | | |
| SDevTC: Version 2.4 | PC | 2.4 | Original | | DTL-S2200 | |
| The Secret of Monkey Island | PC | 2.3 | Original | | 2147010-590001 / I 042 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Bundle Version Creative Labs OEM | | 1713310341 | |
| Shogo: Mobile Armor Division | PC | 2.2 | Covermount | | | |
| Sekai Saikyou Ginsei Igo 世界最強銀星囲碁 | PC | 2.2 | Great Series | | MKW-161 | |
| Sword of the New World: Granado Espada | PC | 2.1.18 | | | | |
| Storybook Weaver Deluxe | PC | 2.1 | Rerelease | | SBW744EE-CD | |
| Serious Sam II | PC | 2.068.00 : 62787 | Covermount | | | |
| Serious Sam II | PC | 2.068.00 : 62787 | | | Y03G0017 | |
| The Settlers IV ザ・セトラーズ4 | PC | 2.04.1090 | | | | |
| Shining Force III: Scenario 1: Outo no Kyoshin シャイニング・フォースⅢ シナリオ1 ~王都の巨神~ | SS | 2.005 | Original | | GS-9175 | |
| Super Shanghai 2005 スーパー上海2005 | NAOMI | 2.001 | Original | | GDL-0031A | |
| SpaceHaste 2 SpaceHaste: The Next Levels | PC | 2.001 | Covermount | | | |
| Space Channel 5 Part 2 スペース・チャンネル5 パート2 | DC | 2.000 | Original | | HDR-0190 | |
| Shining Force III: Scenario 2: Nerawareta Miko シャイニング・フォースⅢ シナリオ2 ~狙われた神子~ | SS | 2.000 | Original | | GS-9188 | |
| Sega Screams Volume 2 | SS | 2.000 | Not for Resale | | 81077 | |
| Sega Saturn Choice Cuts | SS | 2.000 | Bundled with Sega Saturn | | 81600 | |
| Sega Network Taisen Mahjong MJ3 Evolution セガ・ネットワーク対戦麻雀MJ3 EVOLUTION | CHIHIRO | 2.000 | Original | | GDX-0021A | |
| Super Bender Boot Disc | PS2 | 2.00 | | | | |
| Summer Days サマーデイズ | PC | 2.00 | Hibaihin | | | |
| Spy Fox in "Dry Cereal" | PC | 2.00 | Original | | Part #04-00000H1407 | |
| SpellForce 2: Gold Edition | PC | 2.00 | SpellForce Universe | | JOW 009PC LAB2 | |
| SingStar '80s | PS2 | 2.00 | Bundled with Microphones | | SCES-53604 … | |
| SimCity Classic | PC | 2.00 | Original | | | |
| Shanghai: Great Moments | PC | 2.00 | Bundle Version Canon OEM | | | |
| SimCity 3000 Unlimited | PC | 2.0.949.0 | Original | | 1500907 | |
| Sega Rally 2 (Install Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Sega Rally 2 (Play Disc) Sega Rally 2: Sega Rally Championship | PC | 2.0.0.2 | Original | | MK-85078-40 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 2.0.0 | Original | | | |
| Systemax Ultimate Software Collection (Disc 22) (Richard Scarry's: Busy Town) | PC | 2.0 | Original | | | |
| SWAT 3: Close Quarters Battle (Disc 2) (Tactics Disc) | PC | 2.0 | Tactical Game of the Year Edition: SWAT 4 | | | |
| SWAT 3: Close Quarters Battle (Disc 1) (Play Disc) | PC | 2.0 | Tactical Game of the Year Edition: SWAT 4 | | | |
| Su Doku Classic 2 | PC | 2.0 | Covermount | | | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | 10049 | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | SBW744DE-CD | |
| Storybook Weaver Deluxe | PC | 2.0 | Rerelease | | #SBW744BE-CD | |
| Stellar Forces Stellar Forces Expansion Pak: Over 50 Add-On Levels for StarCraft | PC | 2.0 | Original | | | |
| Stella Gets a New Brain! | PC | 2.0 | Original | | AR-4602 | |
| Star Wars: X-Wing vs. TIE Fighter: The Academy | PC | 2.0 | Bundle Version Diamond OEM | | 75000203-100 | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 2.0 | Original | | | |
| Star Trek: The Next Generation: Interactive Technical Manual | PC | 2.0 | Original | | | |
| Sport Image: World Cup 1994 | PC | 2.0 | SoftKey | | WCF344AE-CD | |
| Sophie's World ソフィーの世界 | PC | 2.0 | Original | | | |
| Solitaire: 50 Complete Games! | PC | 2.0 | Rerelease | | 10-0990-10 | |
| SN Systems Installation Disc v2.0 | PC | 2.0 | Original | | | |
| SimCity Classic | PC | 2.0 | Deluxe Edition | | 0002-000-0601B | |
| Il Signore di Atlantide: Poseidon | PC | 2.0 | Original | | S0027713 | |
| Shrak Shrak for Quake | PC | 2.0 | Rerelease | | | |
| Sesame Street: Toddlers Deluxe (Disc 3) (Numbers) | PC | 2.0 | Original | | STO844AE-CD-3 | |
| Sesame Street: Toddlers Deluxe (Disc 2) (Letters) | PC | 2.0 | Original | | STO844AE-CD-2 | |
| Sesame Street: Toddlers Deluxe (Disc 1) (Art Workshop) | PC | 2.0 | Original | | STO844AE-CD-1 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 2) (Search & Learn Adventures) | PC | 2.0 | | | SPC844AE-CD-2 | |
| Sesame Street: Elmo's Preschool Deluxe (Disc 1) (Elmo's Preschool) | PC | 2.0 | | | SPC844AE-CD-1 | |
| Sesame Street Reading is Fun! Toddler (Disc 2) (The Three Grouchketeers) | PC | 2.0 | Original | | SRF844AE-CD-2 | |
| Sesame Street Reading is Fun! Toddler (Disc 1) (Grover's Travels) | PC | 2.0 | Original | | SRF844AE-CD-1 | |
| Scrabble Complete | PC | 2.0 | Rerelease | | Part # 26022CDA | |
| Scrabble | PC | 2.0 | Rerelease | | 99182, Product# 99182 | |
| SonicFury: Software and Documentation | PC | 2 | | | 8/00 11K39 | |
| Sherlock Holmes: Consulting Detective: Vol. I | PC | 2 | Original | | CDRM 770000 | |
| SDevTC: Version 2 | PC | 2 | Original | | | |
| The Sims 3: University Life (Expansion Pack) | PC | 18.0.126.021001 | Original | | MXX09209713D | |
| Surface Tension | PC | 14.7.96 | Original | | | |
| Subwar 2050 | CD32 | 13.11.94 | Original | | | |
| Star Trek: Deep Space Nine: The Fallen | PC | 11-2000-a | Demo | | | |
| SpaceChem | PC | 1012 | Limited Edition | | | |
| SpaceChem | PC | 1011 | Original | | | |
| Silent Steel | PC | 1.82.42.100 | DVD-ROM | | | |
| Squad Assault: Second Wave | PC | 1.80 | Original | | | |
| Sacred (Disc 2) | PC | 1.8 | Rerelease | | 10153-CD2 | |
| Sacred (Disc 1) | PC | 1.8 | Rerelease | | 10153-CD1 | |
| Star Wars: Rebel Assault | PC | 1.7 | White Label, Rerelease | | 632630, CDRM1151470, CDRS1151470 | |
| Sid Meier's Civilization IV | PC | 1.61 | Sid Meier's Civilization Chronicles | | 51989/DVD1 | |
| Sid Meier's Civilization IV | PC | 1.61 | Bundle Version Gigabyte OEM | | 12DD1-2KCIV4-10R | |
| Sports Car GT | PC | 1.52m | Bundle Version OEM | | | |
| The Settlers II: Nowe Misje | PC | 1.51 | Strefa Niskich Cen | | | |
| The Settlers II | PC | 1.51 | Strefa Niskich Cen | | | |
| S.T.A.L.K.E.R.: Clear Sky BGamer 168 | PC | 1.5.10 | Covermount | | | |
| Super Street Fighter II Turbo | PC | 1.5 | | | | |
| Su-27 Flanker Су-27 Фланкер | PC | 1.5 | Original | | | |
| State of War: Warmonger | PC | 1.5 | Original | | | |
| Star Wars: X-Wing: Collector's CD-ROM | PC | 1.5 | Original | | | |
| SpellForce: Platinum Edition | PC | 1.5 | SpellForce Universe | | JOW 009PC LAB1 | |
| Silent Hunter 4: Wolves of the Pacific Silent Hunter 4: Wolves of the Pacific: U-Boat Missions | PC | 1.5 | Gold Edition | | 684589-DVD1 | |
| Skoki Narciarskie 2002: Polskie Złoto | PC | 1.44 | Covermount | | | |
| SWAT 3: Close Quarters Battle | PC | 1.400 | Elite Edition: Covermount | | | |
| Surfroid: Densetsu no Surfer サーフロイド ~伝説のサーファー~ | PS2 | 1.40 | Taikenban | | SLPM 60118 | |
| Sentient | PC | 1.4.0.124 | Original | | | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, 636130 | |
| Star Wars: Rebel Assault: Super Sampler | PC | 1.4 | | | 636030, CDRM1221330 | |
| Star Wars: Rebel Assault | PC | 1.4 | Original | | 632630, CDRM1151470, DRS1151470 | |
| Star Wars: Rebel Assault | PC | 1.4 | Original | | | |
| Skunny Kart | PC | 1.4 | Original | | Art. Nr. 11 10810 | |
| S.V.I.N. (Disc 2) С.В.И.Н. | PC | 1.4 | | | | |
| S.V.I.N. (Disc 1) С.В.И.Н. | PC | 1.4 | | | | |
| STCC: Swedish Touring Car Championship | PC | 1.32 | Covermount | | | |
| Space Empires V | PC | 1.30 | Covermount | | | |
| Świat Gier Komputerowych 2/03 (Disc 2) | PC | 1.3 | | | | |
| Stronghold FireFly Studios' Stronghold | PC | 1.3 | Interactive Demo | | | |
| Star Wars: Rogue Squadron 3D | PC | 1.3 | Rerelease | | 6521830 | |
| Sorry! | PC | 1.3 | Original | | 99040 | |
| Sanguozhi Shu-Han Yingxiongzhuan 三國志 蜀漢英雄傳 | PC | 1.3 | Original | | | |
| Samanta Svift. Tajna Atlantidy' Саманта Свифт. Тайна Атлантиды | PC | 1.3 | Original | | | |
| SimTunes | PC | 1.2nre | Kids Classics | | 1128707 | |
| SimCity 2000: CD Collection | PC | 1.2cj | Windows | | 0026-000-0601-A | |
| Sid Meier's Civilization III | PC | 1.29f | Game of the Year Edition (Bundle Version Packard Bell OEM) | | 70040800ZZ | |
| The Settlers III: Złota Edycja (Disc 2) | PC | 1.25.0.125 | | | | |
| The Settlers III: Złota Edycja (Disc 1) | PC | 1.25.0.125 | | | | |
| The Settlers III: Nowe Misje (Disc 2) | PC | 1.25.0.125 | Original | | | |
| The Settlers III: Nowe Misje (Disc 1) | PC | 1.25.0.125 | | | | |
| The Settlers III: Misja Amazonek | PC | 1.25.0.125 | Original | | | |
| Silent Steel | PC | 1.24.18.121 | Bundle Version Packard Bell OEM: Demo | | 170308 | |
| SharkPort: Code and Save Transfer Kit | PS2 | 1.23 | Unlicensed | | | |
| Shan Yu E: Shenshoudao 善與惡:神獸島 | PC | 1.23 | Quanzhongwen Wanzhengban | | | |
| The Settlers III (Disc 1) 工人物語III | PC | 1.23 | Original | | | |
| Sega Worldwide Soccer 2000 | DC | 1.200 | Sample | | 952-0007-50 | |
| Starball | PC | 1.20 | Original | | | |
| Software & Document: Master CD for Video Family | PC | 1.20 | Bundle Version Jaton OEM | | | |
| Silent Hill 2 | PS2 | 1.20 | Beta | | | |
| Świat Gier Komputerowych 5/02 (Disc 1) Master of Orion II: Battle at Antares | PC | 1.2 | | | | |
| Super Solvers: Spellbound! | PC | 1.2 | Bonus CD | | SRS744AE-CD | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.2 | Rerelease | | 381427-CD3 | |
| Strife | PC | 1.2 | Original | | | |
| Strategy Games of the World | PC | 1.2 | Bundle Version IBM OEM | | P/N 75H9348 | |
| Storybook Weaver Deluxe | PC | 1.2 | Rerelease | | HCD642-CD | |
| Stonekeep | PC | 1.2 | Covermount | | CD-ICD-045-EME | |
| Stonekeep | PC | 1.2 | Rerelease | | CD-ICD-045-1 | |
| StationMaster 2/2002 AR2v2 | PS2 | 1.2 | Unlicensed | | | |
| Star Wars: Rebel Assault | PC | 1.2 | Original | | 632630, CDRM1142600 | |
| Ski-Doo X-Team Racing | PC | 1.2 | Rerelease | | SKI844AB-CD | |
| Singles: Flirt Up Your Life! | PC | 1.2 | | | | |
| SimCity 2000: CD Collection | PC | 1.2 | Windows | | 0026-000-0601-A | |
| SimCity 2000 | PC | 1.2 | Bundle Version Diamond OEM | | 0059-031-0601-A | |
| Shadow Company: Left for Dead | PC | 1.2 | Covermount | | | |
| Sanguozhi Fengyun Zaiqi 三國志·風雲再起 | PC | 1.2 | Original | | | |
| Samanta Svift. Tajna Zolotogo Prikosnoveniya Саманта Свифт. Тайна Золотого Прикосновения | PC | 1.2 | Original | | | |
| Safari Kongo | PC | 1.2 | Original | | | |
| Shtorm Шторм | PC | 1.16.19r | Original | | | |
| System Shock 2 | PC | 1.15 | Original | | LGE08902537D | |
| Star Trek: Starfleet Academy | PC | 1.15 | Bundle Version OEM (DVD-ROM) | | CD-DVD-069-GQE | |
| Sonic CD | MCD | 1.15 | Beta | | | |
| Sub Culture 海底文明 | PC | 1.14 | Original | | | |
| Stealth Combat BGamer 063 (Disc 1) | PC | 1.13 | Covermount | | | |
| Swap Magic | PS2 | 1.12 | Unlicensed | | | |
| Super Solvers: Spellbound! | PC | 1.12 | Rerelease | | SBO744CE-CD | |
| Super Solvers: OutNumbered! | PC | 1.12 | Rerelease | | CSO744BE-CD | |
| Super Solvers: Midnight Rescue! | PC | 1.12 | Rerelease | | CSM744BE-CD | |
| Shattered Steel | PC | 1.12 | Rerelease | | CD-ICD-732-0 | |
| Super Solvers: Spellbound! | PC | 1.11 | Rerelease | | SBO744BE-CD | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.11 | Rerelease | | GAG744BE-CD | |
| SpellForce: The Order of Dawn (Disc 2) (Install CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| SpellForce: The Order of Dawn (Disc 1) (Install/Play CD) | PC | 1.11 | Bundle Version Gigabyte OEM | | | |
| Sonic CD | MCD | 1.11 | Beta | | | |
| The Settlers IV: Misje Dodatkowe | PC | 1.10.908 | | | | |
| Spielbare Cheats Volume 23 | PS2 | 1.10 (European) | Unlicensed | | | |
| Star Wars: X-Wing vs. TIE Fighter: Balance of Power | PC | 1.10 | Original | | | |
| Star Trek Pinball | PC | 1.10 | Rerelease | | CD-C95-675-2 | |
| Selector Demo 01 | PS2 | 1.10 | | | SCED-50811 | |
| SimCity 4 Deluxe Edition (Disc 2) | PC | 1.1.610.0 | Original | | 1474017 | |
| Spaceship Warlock | PC | 1.1.3 "MPC" | Ultimate Game Collection | | | |
| Siege of Avalon Anthology | PC | 1.1.2001.913 | Original | | | |
| The Sum of All Fears | PC | 1.1.1.0 | Best Games | | | |
| The Sims 2: University (Expansion Pack) (Disc 2) | PC | 1.1.0.230 | Original | | 1491717 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | | | 1491707 | |
| The Sims 2: University (Expansion Pack) (Disc 1) | PC | 1.1.0.230 | Original | | 1491707 | |
| Scholastic's The Magic School Bus Explores the Human Body | PC | 1.1.0.2 | Original | | 0396 Part No. 90612, Disc Assy. 299-056-002 | |
| The Suffering | PC | 1.1.0.1 | Covermount | | | |
| Shenhai Zhengba 深海争霸 | PC | 1.1.0 | Original | | | |
| SimCity Classic | PC | 1.1 (Windows), 1.4 (Mac) | Scholastic | | 0002-000-0612-A | |
| Super Solvers: Spellbound! | PC | 1.1 | Rerelease | | SBO744AE-CD | |
| Super Solvers: Spellbound! | PC | 1.1 | Rerelease | | | |
| Super Solvers: Spellbound! | PC | 1.1 | Covermount, Softkey | | SLB844AB-CD | |
| Super Solvers: OutNumbered! | PC | 1.1 | Rerelease | | CSO744AE-CD | |
| Super Solvers: Midnight Rescue! | PC | 1.1 | Rerelease | | CSM744AE-CD | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.1 | Original | | GAG744AE-CD | |
| Suguri スグリ | PC | 1.1 | Original | | | |
| Su-27 Flanker | PC | 1.1 | | | CD090269 | |
| Stronghold | PC | 1.1 | Original | | | |
| Storybook Weaver Deluxe | PC | 1.1 | Original | | Product #HCD642 | |
| Steel Panthers | PC | 1.1 | Awesome 4 Pak | | | |
| StationMaster 3/2002 AR2v2 | PS2 | 1.1 | Unlicensed | | | |
| Star Crusader | PC | 1.1 | Bundle Version OEM | | 0061-0085-01 | |
| Space Station Simulator | PC | 1.1 | Original | | | |
| Space Invaders | PC | 1.1 | Xplosiv | | XP-1867 EUROPEAN | |
| Sonic CD | PC | 1.1 | Expert Software | | 6805 02 | |
| Sing-Along Kids | PC | 1.1 | Original | | | |
| SimPark | PC | 1.1 | Rerelease, Scholastic | | 1126207, 5710372C SP1 | |
| Sihai Xiongdi (Disc 3) 四海兄弟 | PC | 1.1 | Original | | | |
| Sihai Xiongdi (Disc 2) 四海兄弟 | PC | 1.1 | Original | | | |
| Sihai Xiongdi (Disc 1) 四海兄弟 | PC | 1.1 | Original | | | |
| Shinji Sougeki Carnival 神事双劇カーニバル | PC | 1.1 | Original | | TTCA-0902 | |
| The Shadow of the Third Moon | ACD | 1.1 | Original | | | |
| Secrets of Great Art | PC | 1.1 | Original | | P/N 61218-CD | |
| Sammy's Science House | PC | 1.1 | Original | | | |
| S²: Silent Storm (Disc 2) | PC | 1.1 | | | | |
| S²: Silent Storm (Disc 1) | PC | 1.1 | | | | |
| Star Crusader | PC | 1.0n | Bundle Version OEM | | 0061-0085-00 | |
| Sid Meier's Alpha Centauri | PC | 1.0I | CD-ROM Classics | | | |
| Sid Meier's Alpha Centauri | PC | 1.0I | Original | | ORE08901524D | |
| Sid Meier's Alpha Centauri 半人马座 | PC | 1.0I | Original | | | |
| Sonic CD | MCD | 1.09 | Beta | | | |
| Silver (Disc 2) | PC | 1.08C | | | | |
| Silver (Disc 1) | PC | 1.08C | | | | |
| Space Channel 5 Theme Music: Mexican Flyer スペース・チャンネル5 | DC | 1.080 | Not for Sale | | | |
| Shattered Steel | PC | 1.08 | | | CD-ICD-201-M9 | |
| Spectre VR | PC | 1.07wp | Ultimate Game Collection | | | |
| Soldier of Fortune | PC | 1.07f | Platinum Edition (Xplosiv) (Covermount) | | | |
| Sanguo Qunyingzhuan III (Disc 2) (Youxipan) 三国群英传Ⅲ | PC | 1.06C | Original | | | |
| Sanguo Qunyingzhuan III (Disc 1) (Anzhuangpan) 三国群英传Ⅲ | PC | 1.06C | Original | | | |
| Sea Dogs: Piraci | PC | 1.06 | Original | | | |
| StarCraft | PC | 1.05b | StarCraft Battle Chest | | S0437070 | |
| Samidare 五月雨 | PC | 1.051 | Original | | PNB-001 | |
| Stonekeep | PC | 1.05 | Original | | CD-ICD-045-0 | |
| Stonekeep | PC | 1.05 | Covermount | | | |
| Stonekeep | PC | 1.05 | Original, Covermount | | CD-ICD-045-UK | |
| StarCraft | PC | 1.05 | StarCraft Battle Chest, Rerelease | | S7154910 | |
| StarCraft | PC | 1.05 | StarCraft Battle Chest | | S0437070 | |
| StarCraft | PC | 1.05 | TEEN | | S0437070 | |
| StarCraft | PC | 1.05 | TEEN | | LGS-TG-037 | |
| Spectre VR | PC | 1.05 | Original | | | |
| Sonic the Hedgehog CD | MCD | 1.05 | Beta | | | |
| Sky Surfer | PS2 | 1.05 | Preview Build | | SLPS-20012 | |
| Sins of a Solar Empire | PC | 1.05 | Covermount | | | |
| Samidare 五月雨 | PC | 1.05 | Original | | PNB-001 | |
| Super Robot Taisen MX Portable スーパーロボット大戦 MX ポータブル | PSP | 1.04 | Original | | ULJS-00041 | |
| Strategy Challenges Collection 1 | PC | 1.04 | Original, OEM Bundle | | 102771 | |
| Stanley's Sticker Stories | PC | 1.04 | Original | | 381428-CD4/I083ha | |
| Split/Second スプリットセカンド | PSP | 1.04 | Original | | ULJM 05812 | |
| Shaqiu Mobao: Huangquan Zhengba (Disc 4) (Ordos Jiazu) 沙丘魔堡:皇權爭霸 | PC | 1.04 | Original | | | |
| Shaqiu Mobao: Huangquan Zhengba (Disc 3) (Harkonnen Jiazu) 沙丘魔堡:皇權爭霸 | PC | 1.04 | Original | | | |
| Shaqiu Mobao: Huangquan Zhengba (Disc 2) (Atreides Jiazu) 沙丘魔堡:皇權爭霸 | PC | 1.04 | Original | | | |
| Shaqiu Mobao: Huangquan Zhengba (Disc 1) (Anzhuang Guangdie) 沙丘魔堡:皇權爭霸 | PC | 1.04 | Original | | | |
| Sail 2000 | PC | 1.04 | Original | | | |
| Skoki Narciarskie 2001: Polski Zwycięzca | PC | 1.03e | Covermount | | | |
| Supreme Snowboarding | PC | 1.033 | Pringles | | VG-1012 | |
| Space Quest: Collector's Edition Space Quest: 15th Anniversary Collector's Edition | PC | 1.032 | Original | | S343BBZZ12ZZZ | |
| The Suffering | PS2 | 1.03 | Demo | | SLED-52488 | |
| Stickybear Preschool | CDI | 1.03 | Beta | | 690 2572 | |
| Star Wars: Jedi Knight II: Jedi Outcast | PC | 1.03 | Rerelease | | 9541830R1 | |
| Solid State Pinball: Crystal Caliburn Crystal Caliburn | PC | 1.03 | Game-Pack | | 80110 | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | 1000910.101.US | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| Soldier of Fortune | PC | 1.03 | Bundle Version ASUS OEM | | | |
| Simple 2500 Series Portable!! Vol. 10: The IQ Cube: Moyatto Atama o Puzzle de Sukkiri! SIMPLE2500シリーズポータブル!! Vol.10 THE IQ CUBE ~モヤっと頭をパズルでスッキリ!~ | PSP | 1.03 | Original | | ULJS 00108 | |
| Sangokushi VII 三國志Ⅶ | PSP | 1.03 | Original | | ULJM 05083 | |
| Special Disc with SegaSaturn Internet 2 SPECIAL DISC with SEGASATURN インターネット2 | SS | 1.020 | Hibaihin | | T-31303G | |
| The Settlers IV | PC | 1.02.764 | | | | |
| Star Trek: Starfleet Command: Gold Edition | PC | 1.02.01 | Covermount | | CD-W581177-DSE | |
| SpellForce 2: Shadow Wars | PC | 1.02 Build #111632 | Bundle Version Leadtek OEM | | Y03G0009 | |
| Syphon Filter: The Omega Strain | PS2 | 1.02 | Beta | | SCUS 97397 | |
| Świat Gier Komputerowych 5/01 (Disc 1) Sid Meier's Civilization II | PC | 1.02 | | | | |
| Świat Gier Komputerowych 11/02 (Disc 2) Original War | PC | 1.02 | | | | |
| Świat Gier Komputerowych 11/02 (Disc 1) Original War | PC | 1.02 | | | | |
| Suzumiya Haruhi-chan no Mahjong 涼宮ハルヒちゃんの麻雀 | PSP | 1.02 | Original | | ULJM 05751 | |
| The Suffering | PS2 | 1.02 | Original | | SLES-51693 | |
| Starsiege | PC | 1.02 | Original | | | |
| Star Wars: The Clone Wars | PS2 | 1.02 | Original | | SLES-50828 | |
| Speed Busters | PC | 1.02 | Demo | | | |
| Space Invaders Evolution | PSP | 1.02 | Original | | ULES-00348 | |
| SNK Arcade Classics Vol. 1 SNK 아케이드 클래식 Vol.1 | PSP | 1.02 | Original | | ULKS 46179 | |
| SingStar Party | PS2 | 1.02 | Demo | | SCED-52935 | |
| Sierra Pro Pilot (Disc 1) (Scenario USA) | PC | 1.02 | Covermount | | S0013015 | |
| Sierra Pro Pilot (Disc 1) (Scenario Europa) | PC | 1.02 | Covermount | | S0013016 | |
| Sidewinder Max サイドワインダーマックス | PS2 | 1.02 | Taikenban | | SLPM 60128 | |
| Shougi ga Tsuyokunaru: Gekisashi: Jouseki Doujou 将棋が強くなる 激指 定跡道場 | PSP | 1.02 | Original | | ULJM 05263 | |
| Shinkyoku Soukai Polyphonica: 0~4 wa Full Pack 神曲奏界ポリフォニカ 0~4話フルパック | PSP | 1.02 | Original | | ULJM-05347 | |
| Shadow of Memories | PSP | 1.02 | Original | | ULJM-05512 | |
| Shadow Hearts シャドウ ハーツ | PS2 | 1.02 | Taikenban | | SLPM 60145 | |
| Serious Sam: The First Encounter | PC | 1.02 | Bundle Version Gainward OEM | | | |
| Sengoku Efuda Yuugi: Hototogisu Tairan 戦国絵札遊戯 不如帰 大乱 | PSP | 1.02 | Original | | ULJS 00326 | |
| Sega Rally 2006 セガラリー2006 | PS2 | 1.02 | Taikenban | | SLPM 61137 | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.02 | | | 380849B-CD | |
| SBK 09: Superbike World Championship | PSP | 1.02 | Original | | ULES-01247 | |
| Strikers 1945 | SS | 1.01J | Sample | | ST-14407G | |
| Süpercan | PC | 1.01b | Original | | | |
| Star Trek: The Next Generation: A Final Unity | PC | 1.01a | Rerelease | | 1-124-40-101 | |
| Spartan | PC | 1.013 | Covermount | | | |
| Sega Internet-Selain | SS | 1.012 | Bundled with Net Link Internet Modem | | 80124 | |
| Shenmue: Ichishou Yokosuka (Shenmue Passport) シェンムー 一章 横須賀(シェンムーパスポート) | DC | 1.010 | Genteiban | | HDR-0031 | |
| Syphon Filter: Dark Mirror | PSP | 1.01 | Demo | | UCED-00413 … | |
| SWAT: Target Liberty | PSP | 1.01 | Original | | ULUS-10314 | |
| Suzumiya Haruhi no Tomadoi: Uchuu-hatsu! Full CG: Odoru SOS-dan (Chou Eizou-ban) 涼宮ハルヒの戸惑 宇宙初!フルCG 「踊るSOS団」 | PS2 | 1.01 | Yoyaku Tokuten Disc | | SLPM 68020 | |
| Surveillance: Kanshisha サーヴィランス 監視者 | PS2 | 1.01 | Taikenban | | PAPX 90220 | |
| SuperTest | CDI | 1.01 | Beta | | 810 0168 | |
| Super Solvers: Gizmos & Gadgets! | PC | 1.01 | Rerelease | | | |
| Super Solvers Mission: T.H.I.N.K. | PC | 1.01 | Original | | MEM744CE-CD | |
| Super Solvers Mission: T.H.I.N.K. | PC | 1.01 | Original | | MEM744BE-CD | |
| Summoner 2 | PS2 | 1.01 | Demo | | SLED-51091 | |
| Stolen | PS2 | 1.01 | Demo | | SLED-53137 | |
| Steamboy スチームボーイ | PS2 | 1.01 | Taikenban | | SLPM 60265 | |
| Starsky & Hutch | PS2 | 1.01 | Demo | | SLED-51651 | |
| Star Wars: Super Bombad Racing | PS2 | 1.01 | Original | | SLES-50205 | |
| Star Wars: Lethal Alliance | PSP | 1.01 | Original | | ULES-00599 | |
| Star Wars: Battlefront II | PS2 | 1.01 | Beta | | SLUS-29164 | |
| Star Wars: Battlefront II | PS2 | 1.01 | Beta | | SLUS-21240 | |
| Star Wars: Battlefront | PS2 | 1.01 | Review Final | | SLES-52545 | |
| SSX 3 | PS2 | 1.01 | Cheheompan | | SLKA 90502 | |
| Sphinx and the Shadow of Set Sphinx and the Cursed Mummy | PS2 | 1.01 | Demo | | SLUS 29057 | |
| SpeSaru Disc 2003 スペサルディスク2003 | PS2 | 1.01 | Hibaihin | | SCPM 85303 | |
| Speed Racer Speed Racer: The Videogame | PS2 | 1.01 | Original | | SLES-55075 | |
| Speed Busters | PC | 1.01 | Covermount | | | |
| Space Station Simulator | PC | 1.01 | Original | | | |
| Soulcalibur III ファミ通PS2 12月9日号増刊 ファミ通Playable ソウルキャリバーⅢ | PS2 | 1.01 | Taikenban Special Disk | | SLPM 61133 | |
| Sora no Kiseki: Material Collection Portable Mini 空の軌跡 マテリアルコレクション ポータブルmini | PSP | 1.01 | Taikenban | | ULJM 91016 | |
| Sony Computer Science Kenkyuusho Mogi Kenichirou Hakushi Kanshuu: Nou ni Kaikan Minna de Aha Taiken ソニーコンピュータサイエンス研究所 茂木健一郎博士監修 脳に快感 みんなでアハ体験! | PSP | 1.01 | Original | | ULJM-05189 | |
| Sonic CD | PC | 1.01 | Bundle Version OEM | | P/N 647107-001 | |
| Sonic CD | PC | 1.01 | Bundle Version Packard Bell OEM | | 170882, P/N 647107-002 | |
| SOCOM: U.S. Navy SEALs: Fireteam Bravo 3 | PSP | 1.01 | Original | | UCUS-98716 | |
| Slam Dunk Typing All-Star Typing: Ages 9-12: Slam Dunk Typing | PC | 1.01 | Rerelease | | TYN744BE-CD | |
| SkyGunner スカイガンナー | PS2 | 1.01 | Tentou-you Taikenban | | PCPX 96321 | |
| SkyGunner スカイガンナー | PS2 | 1.01 | Taikenban | | PAPX 90218 | |
| SingStar '80s | PS2 | 1.01 | Original | | SCES-53603 | |
| Sin SiN | PC | 1.01 | Original | | 1000076.101.US | |
| Sin SiN | PC | 1.01 | Rerelease | | 6236-01 | |
| Sin (Patch v1.01) SiN | PC | 1.01 | Original | | 1000076.102.UK | |
| Simple 2500 Series Portable!! Vol. 11: The Puzzle Quest: Agaria no Kishi SIMPLE2500シリーズポータブル!! Vol.11 THE パズルクエスト ~アガリアの騎士~ | PSP | 1.01 | Original | | ULJS-00114 | |
| The Silver Case | PC | 1.01 | Limited Run Games Limited Edition | | | |
| Si Balla! | CDI | 1.01 | Beta | | 815 0066 | |
| Shinigami to Shoujo 死神と少女 | PSP | 1.01 | Original | | ULJS 00403 | |
| Shindou Shippuu Monogatari Mousou Gaiden: Mahou Shoujo Magical Iorin: Second Magic: "Watashi Stalking Hajimemashita!" 神動疾風物語妄想外伝 魔法少女マジカルいおりん ~Second Magic゛私ストーキングはじめました!゛~ | PC | 1.01 | | | | |
| Shin Seiki Evangelion: Koutetsu no Girlfriend 2nd Portable 新世紀エヴァンゲリオン 鋼鉄のガールフレンド2nd ポータブル | PSP | 1.01 | Original | | ULJM 05477 | |
| Shin Seiki Evangelion 2: Tsukurareshi Sekai: Another Cases 新世紀エヴァンゲリオン2 造られしセカイ -another cases- | PSP | 1.01 | Original | | ULJS 00064 | |
| Shin Seiki Evangelion 2: Tsukurareshi Sekai: Another Cases 新世紀エヴァンゲリオン2 造られしセカイ -another cases- | PSP | 1.01 | 10-shuunen Kinen Memorial Box | | ULJS 00061 | |
| Shin Sangoku Musou: Multi Raid 2 真・三國無双 MULTI RAID 2 | PSP | 1.01 | Special Taikenban | | ULJM 91020 | |
| Shin Sangoku Musou: Multi Raid 真・三國無双 MULTI RAID | PSP | 1.01 | Taikenban | | ULJM 91017 | |
| Shin Megami Tensei: Digital Devil Saga 2 | PS2 | 1.01 | Original | | SLES-54555 | |
| Shin Master of Monsters Final EX: Mukunaru Nageki, Tenmei no Saika 真・マスターオブモンスターズ Final EX ~無垢なる嘆き、天冥の災禍~ | PSP | 1.01 | Original | | ULJS 00282 | |
| Shin Combat Choro Q 新コンバットチョロQ | PS2 | 1.01 | Taikenban | | SLPM 61029 | |
| Shattered Steel | PC | 1.01 | Original | | CD-ICD-201-M9 | |
| Shangdi Ye Fengkuang 上帝也疯狂 | PC | 1.01 | Original | | | |
| Shadow Hearts: From the New World シャドウ ハーツ フロム・ザ・ニュー・ワールド | PS2 | 1.01 | Taikenban | | SLPM 60264 | |
| Shadow Hearts II シャドウ ハーツⅡ | PS2 | 1.01 | Taikenban | | SLPM 60214 … | |
| Shadow Hearts II シャドウ ハーツⅡ | PS2 | 1.01 | Furokuban | | SLPM 60219 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Sherlock Holmes: Consulting Detective / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Classics Arcade Collection | MCD | 1.01 | Bundled with Sega CD (Ecco the Dolphin / Sega Classics Arcade Collection Bundle) | | 4126 | |
| Sega Ages 2500 Taikenban SEGA AGES 2500 体験版 | PS2 | 1.01 | Taikenban | | SLPM 61077 | |
| Secret Mission | CDI | 1.01 | Beta | | 810 0272 | |
| Secret Agent Clank | PSP | 1.01 | Original | | UCAS-40218 | |
| Scooby-Doo! Jinx at the Sphinx | PC | 1.01 | Original | | 380849A-CD | |
| Saru! Get You! 2: Ukki Ukki Disc サルゲッチュ2 ウッキーウッキーディスク | PS2 | 1.01 | Hibaihin | | PAPX 90330 | |
| Sanitarium (Disc 2) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) | PC | 1.01 | Original | | | |
| Sanitarium (Disc 1) Шизариум | PC | 1.01 | Original | | | |
| Sangokushi Tai Sen: Dairyuusei 三国志戴閃-大流星- | PC | 1.01 | Original | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00I | Covermount | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00I | Covermount | | | |
| Septerra Core: Legacy of the Creator | PC | 1.00I | Original | | | |
| Sid Meier's Civil War Collection | PC | 1.00f | | | 1225507 | |
| Serious Sam: The First Encounter | PC | 1.00a | Covermount | | | |
| Sakura Taisen (Disc 2) サクラ大戦 | DC | 1.009 | Genteiban | | HDR-0089 | |
| Sakura Taisen (Disc 1) サクラ大戦 | DC | 1.009 | Genteiban | | HDR-0089 | |
| Sonic Adventure 2 | DC | 1.008 | Original | | 51117 | |
| Scorcher | SS | 1.008 | Original | | 81214 | |
| Sakura Taisen Online: Teito no Nagai Hibi サクラ大戦オンライン ~帝都の長い日々~ | DC | 1.007 | Original | | HDR-0184 | |
| Sakura Taisen Dream Passport 3 サクラ大戦 ドリームパスポート 3 | DC | 1.007 | Original | | 610-7996 | |
| Star Wars: Episode I: Racer | DC | 1.005 | Original | | T-13006D-50 | |
| Sports Jam スポーツ・ジャム | NAOMI | 1.005 | Original | | GDS-0003 | |
| The Shinri Game ザ・心理ゲーム | DC | 1.004 | Original | | T-43403M | |
| Sega Flash Vol. 3 | SS | 1.004 | Bundled with Magazine | | 610-6288C | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Disc 3) サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.004 | Original | | GS-9198 | |
| Super Runabout スーパーランナバウト | DC | 1.003 | Original | | T-22101M | |
| Street Fighter III: 3rd Strike: Fight for the Future ストリート・ファイターⅢ サードストライク ~ファイト・フォー・ザ・フューチャー~ | DC | 1.003 | Original | | T-1209M | |
| Sega GT | DC | 1.003 | Original | | MK-51053 | |
| Sega Flash Vol. 4 | SS | 1.003 | Bundled with Magazine | | 610-6288D | |
| Sanguozhi IV 三國志Ⅳ | SS | 1.003 | Zhongwenban | | T-7601H-11, T-7601H-16 | |
| Saka Tsuku Tokudai-gou: J.League Pro Soccer Club o Tsukurou! サカつく特大号 J.LEAGUE プロサッカークラブをつくろう! | DC | 1.003 | Original | | HDR-0126 | |
| Super Runabout スーパーランナバウト | DC | 1.002 | Taikenban | | 610-7803 | |
| Super Prologue 21 Games Vol. 1 スーパー・プロローグ21 ゲームス Vol.1 | SP21 | 1.002 | Original | | SKT-3500 | |
| Street Fighter Zero 3: Saikyo-ryu Dojo for Matching Service ストリートファイターZERO3 サイキョー流道場 フォー マッチング サービス | DC | 1.002 | Original | | T-1230M | |
| Sonic Adventure 2 ソニックアドベンチャー2 | DC | 1.002 | Taikenban | | 610-8057 | |
| Sonic Adventure 2 | DC | 1.002 | Beta | | MK-5111750 | |
| Silent Scope サイレント スコープ | DC | 1.002 | Original | | T-9513M | |
| Shutokou Battle 首都高バトル | DC | 1.002 | Taikenban | | 610-7134 | |
| Shin Seiki Evangelion: Ayanami Ikusei Keikaku 新世紀エヴァンゲリオン 綾波育成計画 | DC | 1.002 | Original | | T-46303M | |
| Sengoku Blade: Sengoku Ace Episode II 戦国ブレード | SS | 1.002 | Mihonhin | | ST-14410G | |
| Seireiki Rayblade 聖霊機ライブレード | DC | 1.002 | Demo | | 610-7747 | |
| SegaKara for Dreamcast セガカラ for ドリームキャスト | DC | 1.002 | Bundled with Dreamcast Karaoke | | 610-7762 | |
| Sega-Race TV セガ-レースTV | LINDBERGH | 1.002 | Lindbergh Yellow | | DVP-0044 | |
| Sega Saturn Bootleg II: On the Road Sega Screams Volume 1 | SS | 1.002 | Not for Resale | | 81068, 81075 | |
| Sega Flash Vol. 5 | SS | 1.002 | Bundled with Magazine, Bundled with Sega Saturn | | 610-6288E | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare (Disc 2) サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.002 | Shokai Tokutenban | | GS-9169 | |
| Super Shanghai 2005 スーパー上海2005 | NAOMI | 1.001 | Original | | GDL-0031 | |
| Super Magnetic Neo | DC | 1.001 | Demo | | T-40206ND | |
| Street Fighter Zero 3: Saikyo-ryu Dojo ストリート・ファイターZERO3 ~サイキョー流道場~ | DC | 1.001 | Tentou Taikenban | | 610-7161 | |
| Street Fighter Zero 3 Upper | NAOMI | 1.001 | Original | | GDL-0002 | |
| Spirit of Speed 1937 | DC | 1.001 | Original | | T-8118N | |
| Space Channel 5 | DC | 1.001 | Original | | MK-51051-50 | |
| Sonic R ソニックR | SS | 1.001 | Taikenban (Otanoshimi 3Shiro! Disc) | | 610-6815 | |
| Sonic Adventure 2: The Trial | DC | 1.001 | Demo | | 610-7994-50 | |
| Solo Crisis ソロ・クライシス | SS | 1.001 | Taiken Sample-ban | | 610-6802 | |
| Slave Zero | DC | 1.001 | Original | | T-15106N | |
| Silhouette Mirage シルエット・ミラージュ | SS | 1.001 | Taikan CD-ROM | | 610-6679 | |
| Senko no Ronde 旋光の輪舞 | NAOMI | 1.001 | Original | | GDL-0030 | |
| Seitai Heiki Expendable 生体兵器 エクスペンダブル | DC | 1.001 | Original | | T-15003M | |
| Sega Worldwide Soccer '97 | SS | 1.001 | Original | | 81112 | |
| Sega Network Taisen Mahjong MJ4 Evolution セガネットワーク対戦麻雀MJ4 Evolution | LINDBERGH | 1.001 | Lindbergh Red EX | | DVP-0081 | |
| Sega Flash Vol. 3 | SS | 1.001 | Bundled with Magazine | | 610-6288C | |
| Sega Flash Vol. 1 | SS | 1.001 | Bundled with Sega Saturn | | MK610-6288A | |
| Seaman Esa Disc: Kimos Shu no Youchuu Hojuu Kit シーマン えさ ディスク <キモス種の幼虫補充キット> | DC | 1.001 | Bundled with Seaman Ikusei Shien Kit | | 610-7804 | |
| SeaBass Fishing シーバス・フィッシング | SS | 1.001 | Original | | T-6005G | |
| Saturn Super Vol. 3 サターン・スーパー Vol.3 | SS | 1.001 | | | 610-6020-03 | |
| Saturn Super Vol. 3 サターン・スーパー Vol.3 | SS | 1.001 | | | 610-6020-03 | |
| Saturn Super Vol. 3 サターン・スーパー Vol.3 | SS | 1.001 | | | 610-6020-03 | |
| SatMag Sono CD サタマガ・ソノCD | SS | 1.001 | Bundled with Magazine (SegaSaturn Taikenban CD-ROM) | | 610-6833 | |
| San Francisco Rush 2049 | DC | 1.001 | Original | | T-9707N | |
| Samurai Spirits: Amakusa Kourin サムライ・スピリッツ ~天草降臨~ | SS | 1.001 | Hibaihin | | 610-6730 | |
| Sakura Taisen 2: Kimi, Shinitamou Koto Nakare サクラ大戦2 ~君、死にたもうことなかれ~ | SS | 1.001 | Tokubetsu-ban (Standalone, Bundled with Mogitate SegaSaturn Vol. 2) | | 610-6864 | |
| Sakura Taisen (Omake Disc) サクラ大戦 | DC | 1.001 | Genteiban | | HDR-0089 | |
| System-Disc (KD02) JVC | SS | 1.000 | Original | | 610-5732-03 | |